Raymond J. MacDonald - Publications, H-index & Citations

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Raymond J. MacDonald

Lancaster University

63H-index

193Paper Count

3.6WCitation Count

Published Papers 44

Publication Date

Experimental synthesis of ThSiO4 by fluid-induced alteration of chevkinite-(Ce): Evidence for element mobility and variable crystal structure

CHEMICAL GEOLOGY

IF3.6

2024-12-01

PREAI

Stachowicz, M.; Baginski, B.; Harlov, D. E.; Jokubauskas, P.; Matyszczak, W.; Kotowski, J.; Macdonald, R.

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NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

NATURE COMMUNICATIONS

IF15.7

2023-06-23

OAAI

Cobo, Isidoro; Paliwal, Sumit; Bodas, Cristina; Felipe, Irene; Melia-Aloma, Julia; Torres, Ariadna; Martinez-Villarreal, Jaime; Malumbres, Marina; Garcia, Fernando; Millan, Irene; del Pozo, Natalia; Park, Joo-Cheol; MacDonald, Ray J.; Munoz, Javier; Mendez, Raul; Real, Francisco X.

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An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2)

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

162

OAAI

Swift, GH; Liu, Y; Rose, SD; Bischof, LJ; Steelman, S; Buchberg, AM; Wright, CVE; MacDonald, RJ

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PTF1 is an organ-specific and notch-independent basic helix-loop-helix complex containing the mammalian suppressor of hairless (RBP-J) or its paralogue, RBP-L

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

220

OAAI

Beres, TM; Masui, T; Swift, GH; Shi, L; Henke, RM; MacDonald, RJ

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Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

100

OAAI

Masui, Toshihiko; Swift, Galvin H.; Hale, Michael A.; Meredith, David M.; Johnson, Jane E.; MacDonald, Raymond J.

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Program Specificity for Ptf1a in Pancreas versus Neural Tube Development Correlates with Distinct Collaborating Cofactors and Chromatin Accessibility

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Meredith, David M.; Borromeo, Mark D.; Deering, Tye G.; Casey, Bradford H.; Savage, Trisha K.; Mayer, Paul R.; Hoang, Chinh; Tung, Kuang-Chi; Kumar, Manonmani; Shen, Chengcheng; Swift, Galvin H.; MacDonald, Raymond J.; Johnson, Jane E.

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Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Hoang, Chinh Q.; Hale, Michael A.; Azevedo-Pouly, Ana C.; Elsaesser, Hans P.; Deering, Tye G.; Willet, Spencer G.; Pan, Fong C.; Magnuson, Mark A.; Wright, Christopher V. E.; Swift, Galvin H.; MacDonald, Raymond J.

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MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Jiang, Mei; Azevedo-Pouly, Ana C.; Deering, Tye G.; Hoang, Chinh Q.; DiRenzo, Daniel; Hess, David A.; Konieczny, Stephen F.; Swift, Galvin H.; MacDonald, Raymond J.

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MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Hess, David A.; Strelau, Katherine M.; Karki, Anju; Jiang, Mei; Azevedo-Pouly, Ana C.; Lee, Ann-Hwee; Deering, Tye G.; Hoang, Chinh Q.; MacDonald, Raymond J.; Konieczny, Stephen F.

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Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

SCIENTIFIC REPORTS

IF3.9

2020-11-26

OAAI

Layeghi-Ghalehsoukhteh, Somayeh; Pal Choudhuri, Shreoshi; Ocal, Ozhan; Zolghadri, Yalda; Pashkov, Victor; Niederstrasser, Hanspeter; Posner, Bruce A.; Kantheti, Havish S.; Azevedo-Pouly, Ana C.; Huang, Huocong; Girard, Luc; MacDonald, Raymond J.; Brekken, Rolf A.; Wilkie, Thomas M.

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Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

DEVELOPMENTAL CELL

IF8.7

2019-09-01

OAAI

Krah, Nathan M.; Narayanan, Shuba M.; Yugawa, Deanne E.; Straley, Julie A.; Wright, Christopher V. E.; MacDonald, Raymond J.; Murtaugh, L. Charles

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Investigation of oncogenic G-protein coupled receptor signaling pathways in Kras dependent pancreatic cancer cell lines

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Ocal, Ozhan; MacDonald, Raymond; Brekken, Rolf A.; Wilkie, Thomas

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An inflammatory transcriptional switch

NATURE

IF48.5

2018-02-14

OAAI

Murtaugh, L. Charles; Macdonald, Raymond J.

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Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation

DIABETES

IF7.5

2016-06-09

OAAI

Houghton, Jayne A. L.; Swift, Galvin H.; Shaw-Smith, Charles; Flanagan, Sarah E.; de Franco, Elisa; Caswell, Richard; Hussain, Khalid; Mohamed, Sarar; Abdulrasoul, Majedah; Hattersley, Andrew T.; MacDonald, Raymond J.; Ellard, Sian

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The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

ELIFE

IF0

2015-07-07

147

OAAI

Krah, Nathan M.; De La O, Jean-Paul; Swift, Galvin H.; Hoang, Chinh Q.; Willet, Spencer G.; Pan, Fong Chen; Cash, Gabriela M.; Bronner, Mary P.; Wright, Christopher V. E.; MacDonald, Raymond J.; Murtaugh, L. Charles

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Dominant and context-specific control of endodermal organ allocation by Ptf1a

DEVELOPMENT

IF3.6

2014-11-15

OAAI

Willet, Spencer G.; Hale, Michael A.; Grapin-Botton, Anne; Magnuson, Mark A.; MacDonald, Raymond J.; Wright, Christopher V. E.

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The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

DEVELOPMENT

IF3.6

2014-08-15

OAAI

Hale, Michael A.; Swift, Galvin H.; Hoang, Chinh Q.; Deering, Tye G.; Masui, Toshi; Lee, Youn-Kyoung; Xue, Jumin; MacDonald, Raymond J.

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Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism (vol 139, pg 33, 2012)

DEVELOPMENT

IF3.6

2012-12-01

OAAI

Ahnfelt-Ronne, Jonas; Jorgensen, Mette C.; Klinck, Rasmus; Jensen, Jan N.; Fuechtbauer, Ernst-Martin; Deering, Tye; MacDonald, Raymond J.; Wright, Chris V. E.; Madsen, Ole D.; Serup, Palle

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Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2012-10-01

148

OAAI

Xuan, Shouhong; Borok, Matthew J.; Decker, Kimberly J.; Battle, Michele A.; Duncan, Stephen A.; Hale, Michael A.; Macdonald, Raymond J.; Sussel, Lori

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Induced Mist1 Expression Promotes Remodeling of Mouse Pancreatic Acinar Cells

GASTROENTEROLOGY

IF25.1

2012-08-01

OAAI

Direnzo, Daniel; Hess, David A.; Damsz, Barbara; Hallett, Judy E.; Marshall, Brett; Goswami, Chirayu; Liu, Yunlong; Deering, Tye; Macdonald, Raymond J.; Konieczny, Stephen F.

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Research Directions