Not logged in AquIRE reveals the mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs Zhang, Zijian; Kotopanova, Zornitsa Vasileva; Dang, Kexin; Kong, Xiangxu; Simms, Nicole; Yuen, Tin wai; Lam, Lan; Beadle, Lauren Forbes; Hilton, Emma; Qureshi, Taqdees; Coppola, Marianna; Holmes, Callum David; Kan, Kwan Ting; Ashe, Mark; Gallois, Patrick; Ashe, Hilary; Braun, Michael; Saunders, Mark; Sutton, Paul; Thornton, David J.; Knight, John R. P. Share Save
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Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil Chatterjee, Susanta; Naeli, Parisa; Onar, Okan; Simms, Nicole; Garzia, Aitor; Hackett, Angela; Coyle, Kelsey; Harris Snell, Patric; McGirr, Tom; Sawant, Tanvi Nitin; Dang, Kexin; Stoichkova, Zornitsa Vasileva; Azam, Yumna; Saunders, Mark P.; Braun, Michael; Alain, Tommy; Tuschl, Thomas; McDade, Simon S.; Longley, Daniel B.; Gkogkas, Christos G.; Adrain, Colin; Knight, John R. P.; Jafarnejad, Seyed Mehdi Share Save
Clinical Trial Data Review of the Combination FTD/TPI plus Bevacizumab in the Treatment Landscape of Unresectable Metastatic Colorectal Cancer Andre, Thierry; Van Cutsem, Eric; Taieb, Julien; Fakih, Marwan; Prager, Gerald W.; Ciardiello, Fortunato; Falcone, Alfredo; Saunders, Mark; Amellal, Nadia; Roby, Lucas; Tabernero, Josep; Pfeiffer, Per Share Save
Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer Nowak, Marta; Jabbar, Faiz; Rodewald, Ann-Katrin; Gneo, Luciana; Tomasevic, Tijana; Harkin, Andrea; Iveson, Tim; Saunders, Mark; Kerr, Rachel; Oein, Karin; Maka, Noori; Hay, Jennifer; Edwards, Joanne; Tomlinson, Ian; Sansom, Owen; Kelly, Caroline; Pezzella, Francesco; Kerr, David; Easton, Alistair; Domingo, Enric; Koelzer, Viktor H.; Church, David N. Share Save
Hyperthermic intraoperative peritoneal chemotherapy and cytoreductive surgery for people with peritoneal metastases: a systematic review and cost-effectiveness analysis Gurusamy, Kurinchi; Leung, Jeffrey; Vale, Claire; Roberts, Danielle; Linden, Audrey; Tan, Xiao Wei; Taribagil, Priyal; Patel, Sonam; Pizzo, Elena; Davidson, Brian; Mould, Tim; Saunders, Mark; Aziz, Omer; O'Dwye, Sarah Share Save
Pre-treatment magnetic resonance imaging in anal cancer: large-scale evaluation of mrT, mrN and novel staging parameters Sekhar, Hema; Kochhar, Rohit; Carrington, Bernadette; Kaye, Thomas; Tolan, Damian; Malcomson, Lee; Saunders, Mark P.; Sperrin, Matthew; Sebag-Montefiore, David; van Herk, Marcel; Renehan, Andrew G. Share Save
Time From Colorectal Cancer Surgery to Adjuvant Chemotherapy Post Hoc Analysis of the SCOT Randomized Clinical Trial Gogenur, Mikail; Rosen, Andreas Weinberger; Iveson, Timothy; Kerr, Rachel S.; Saunders, Mark P.; Cassidy, Jim; Tabernero, Josep; Haydon, Andrew; Glimelius, Bengt; Harkin, Andrea; Allan, Karen; Pearson, Sarah; Boyd, Kathleen A.; Briggs, Andrew H.; Waterston, Ashita; Medley, Louise; Ellis, Richard; Dhadda, Amandeep S.; Harrison, Mark; Falk, Stephen; Rees, Charlotte; Olesen, Rene K.; Propper, David; Bridgewater, John; Azzabi, Ashraf; Cunningham, David; Hickish, Tamas; Gollins, Simon; Wasan, Harpreet S.; Kelly, Caroline; Goegenur, Ismail; Hollaender, Niels Henrik Share Save
Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in genetically selected microsatellite stable colorectal cancer patients Cook, N.; Bridgewater, J. A.; Saunders, M. P.; Kopetz, S.; Garcia-Carbonero, R.; Beom, S-H.; O'Neil, B. H.; Wilson, R. H.; Graham, J.; Maurel, J.; Kim, T. W.; Chau, I.; Saleha, S.; Goodwin, L.; Wilson, D.; Robertson, J.; Timmis, H.; Asken, E.; Woodcock, S. A.; Morris, V. Share Save
Exploring discrepancies in perception: A study of patients' and health professionals' understanding of cancer care Christodoulis, E.; Ntellas, P.; Dadouli, K.; Simpson, L.; Lim, K. H. J.; Shanthappa, A.; Connell, J.; Williams, J.; Anderson, D.; Hasan, J.; Mullamitha, S.; Braun, M.; Marti, K.; Adamou, M.; Saunders, M. P.; Barriuso, J.; Kamposioras, K. V. Share Save
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors Pennel, Kathryn A. F.; Hatthakarnkul, Phimmada; Wood, Colin S.; Lian, Guang-Yu; Al-Badran, Sara S. F.; Quinn, Jean A.; Legrini, Assya; Inthagard, Jitwadee; Alexander, Peter G.; van Wyk, Hester; Kurniawan, Ahmad; Hashmi, Umar; Gillespie, Michael A.; Mills, Megan; Ammar, Aula; Hay, Jennifer; Andersen, Ditte; Nixon, Colin; Rebus, Selma; Chang, David K.; Kelly, Caroline; Harkin, Andrea; Graham, Janet; Church, David; Tomlinson, Ian; Saunders, Mark; Iveson, Tim; Lannagan, Tamsin R. M.; Jackstadt, Rene; Maka, Noori; Horgan, Paul G.; Roxburgh, Campbell S. D.; Sansom, Owen J.; McMillan, Donald C.; Steele, Colin W.; Jamieson, Nigel B.; Park, James H.; Roseweir, Antonia K.; Edwards, Joanne Share Save
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation Dillon, Magnus T.; Guevara, Jeane; Mohammed, Kabir; Patin, Emmanuel C.; Smith, Simon A.; Dean, Emma; Jones, Gemma N.; Willis, Sophie E.; Petrone, Marcella; Silva, Carlos; Thway, Khin; Bunce, Catey; Roxanis, Ioannis; Nenclares, Pablo; Wilkins, Anna; Mclaughlin, Martin; Jayme-Laiche, Adoracion; Benafif, Sarah; Nintos, Georgios; Kwatra, Vineet; Grove, Lorna; Mansfield, David; Proszek, Paula; Martin, Philip; Moore, Luiza; Swales, Karen E.; Banerji, Udai; Saunders, Mark P.; Spicer, James; Forster, Martin D.; Harrington, Kevin J. Share Save
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Genetic and immune landscape evolution in MMR-deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Fong, Caroline; Barber, Louise J.; Anandappa, Gayathri; Crux, Richard; Assiotis, Ioannis; Fenwick, Kerry; Begum, Ruwaida; Begum, Dipa; Lund, Tom; Sivamanoharan, Nanna; Sansano, Harold B.; Domingo-Arada, Melissa; Tran, Amina; Pandha, Hardev; Church, David; Eccles, Bryony; Ellis, Richard; Falk, Stephen; Hill, Mark; Krell, Daniel; Murugaesu, Nirupa; Nolan, Luke; Potter, Vanessa; Saunders, Mark; Shiu, Kai-Keen; Guettler, Sebastian; Alexander, James L.; Lazare-Iglesias, Hector; Kinross, James; Murphy, Jamie; von Loga, Katharina; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Multiparameter immunoprofiling reveals independent prognostic value of intraepithelial CD8 and intrastromal FoxP3 infiltrate in stage II/III colorectal cancer: Analysis of 3,409 cases from the SCOT and QUASAR2 trials Church, D. N.; Frei, A.; McGuigan, A.; Sinha, R.; Harkin, A.; Iveson, T. J.; Saunders, M. P.; Hay, J.; Edwards, J.; Sansom, O. J.; Kelly, C.; Kerr, R.; Kerr, D. J.; Domingo, E.; Koelzer, V. H. Share Save
Psychological well-being of patients with colorectal cancer during the third wave of the COVID-19 pandemic: Results from cohort II of the PICO-SM study Kamposioras, K. V.; Dadouli, K.; Ntellas, P.; Lim, K. H. J.; Adamou, M.; Anderson, D.; Simpson, L.; Shanthappa, A.; Braun, M.; Barriuso, J.; Connell, J.; Williams, J.; Lehwald, D.; Hasan, J.; Mullamitha, S.; Marti, K.; Saunders, M. P. Share Save
Single cell AI-based detection of DNA mismatch repair deficiency in 1,988 colorectal cancers reveals prognostic and predictive value in the SCOT trial Jabbar, F.; Nowak, M.; Rodewald, A-K.; Gneo, L.; Tomasevic, T.; Harkin, A.; Iveson, T. J.; Saunders, M. P.; Kerr, R.; Oien, K. A.; Maka, N.; Hay, J.; Edwards, J.; Tomlinson, I.; Sansom, O. J.; Kelly, C.; Easton, A.; Domingo, E.; Koelzer, V. H.; Church, D. N. Share Save
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets Frei, Anja L.; McGuigan, Anthony; Sinha, Ritik R. A. K.; Glaire, Mark A.; Jabbar, Faiz; Gneo, Luciana; Tomasevic, Tijana; Harkin, Andrea; Iveson, Tim J.; Saunders, Mark; Oein, Karin; Maka, Noori; Pezella, Francesco; Campo, Leticia; Hay, Jennifer; Edwards, Joanne; Sansom, Owen J.; Kelly, Caroline; Tomlinson, Ian; Kildal, Wanja; Kerr, Rachel S.; Kerr, David J.; Danielsen, Havard E.; Domingo, Enric; TransSCOT Consortium, David N.; Church, David N.; Koelzer, Viktor H. Share Save
AN0025, a novel antagonist of PGE2-receptor E-type 4 (EP4), in combination with total neoadjuvant treatment of advanced rectal cancer Wyrwicz, Lucjan; Saunders, Mark; Hall, Marcia; Ng, John; Hong, Theodore; Xu, Sherry; Lucas, Justin; Lu, Xuyang; Lautermilch, Nathan; Formenti, Silvia; Glynne-Jones, Robert Share Save
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