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R

Ralph R. Isberg

Tufts University School of Medicine

80H-index
284Paper Count
2.2WCitation Count
Published Papers 80
Publication Date
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RNA quality control enables antibiotic tolerance
errCell Host & Microbe
IF18.7
err2026-07-22
err0
errOAAI
errAndrew T. Nishimoto; Juan C. Ortiz-Marquez; Michelle R. Scribner; Yanying Yu; Qidong Jia; Haley Echlin; Amy R. Iverson; Abigail E. McKnight; Nadia Olivero; Aaron Poole; Enolia Marr; Jordan Coggins; Adam Rosenthal; Chrispin Chaguza; Randolph K. Larsen; Mark E. Hatley; Ralph R. Isberg; Vaughn S. Cooper; Tim van Opijnen; Jason W. Rosch
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Identification of determinants that allow maintenance of high-level fluoroquinolone resistance in Acinetobacter baumannii
errMBIO
IF4.7
err2025-01-08
err0
errOAAI
errHamami, Efrat; Huo, Wenwen; Hernandez-Bird, Juan; Castaneda, Arnold; Bai, Jinna; Syal, Sapna; Ortiz-Marquez, Juan C.; van Opijnen, Tim; Geisinger, Edward; Isberg, Ralph R.
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errSave
Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway
errMSPHERE
IF3.1
err2024-09-25
err0
errOAAI
errHershkovitz, Dar; Chen, Emy J.; Ensminger, Alexander W.; Dugan, Aisling S.; Conway, Kaleigh T.; Joyce, Alex C.; Segal, Gil; Isberg, Ralph R.
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errSave
Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones
errMBIO
IF4.7
err2024-02-14
err2
errOAAI
errDao, Tina H.; Echlin, Haley; Mcknight, Abigail; Marr, Enolia S.; Junker, Julia; Jia, Qidong; Hayden, Randall; van Opijnen, Tim; Isberg, Ralph R.; Cooper, Vaughn S.; Rosch, Jason W.
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errSave
The Sde phosphoribosyl-linked ubiquitin transferases protect the Legionella pneumophila vacuole from degradation by the host
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-08-07
err3
errOAAI
errKim, Seongok; Isberg, Ralph R.
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errSave
Identification of Genes Required for Long-Term Survival of Legionella pneumophila in Water
errMSPHERE
IF3.1
err2023-04-20
err5
errOAAI
errAurass, Philipp; Kim, Seongok; Pinedo, Victor; Cava, Felipe; Isberg, Ralph R.
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errSave
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-02-14
err7
errOAAI
errMicelli, Carmina; Dai, Yunfei; Raustad, Nicole; Isberg, Ralph R.; Dowson, Christopher G.; Lloyd, Adrian J.; Geisinger, Edward; Crow, Allister; Roper, David I.
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errSave
Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers
errGUT MICROBES
IF11
err2021-11-18
err14
errOAAI
errFasciano, Alyssa C.; Dasanayake, Gaya S.; Estes, Mary K.; Zachos, Nicholas C.; Breault, David T.; Isberg, Ralph R.; Tan, Shumin; Mecsas, Joan
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errSave
SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase
errCELL REPORTS
IF6.9
err2021-11-01
err17
errOAAI
errChoi, Won Young; Kim, Seongok; Aurass, Philipp; Huo, Wenwen; Creasey, Elizabeth A.; Edwards, Marc; Lowe, Martin; Isberg, Ralph R.
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errSave
Members of the Legionella pneumophila Sde family target tyrosine residues for phosphoribosyl-linked ubiquitination
errRSC CHEMICAL BIOLOGY
IF3.1
err2021-01-01
err21
errOAAI
errZhang, Mengyun; McEwen, Joseph M.; Sjoblom, Nicole M.; Kotewicz, Kristin M.; Isberg, Ralph R.; Scheck, Rebecca A.
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errSave
Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope (vol 11, 4522, 2020)
errNATURE COMMUNICATIONS
IF15.7
err2020-11-24
err1
errOAAI
errGeisinger, Edward; Mortman, Nadav J.; Dai, Yunfei; Cokol, Murat; Syal, Sapna; Farinha, Andrew; Fisher, Delaney G.; Tang, Amy Y.; Lazinski, David W.; Wood, Stephen; Anthony, Jon; van Opijnen, Tim; Isberg, Ralph R.
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errSave
Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
errNATURE COMMUNICATIONS
IF15.7
err2020-09-09
err58
errOAAI
errGeisinger, Edward; Mortman, Nadav J.; Dai, Yunfei; Cokol, Murat; Syal, Sapna; Farinha, Andrew; Fisher, Delaney G.; Tang, Amy Y.; Lazinski, David W.; Wood, Stephen; Anthony, Jon; van Opijnen, Tim; Isberg, Ralph R.
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errSave
Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity
errNATURE COMMUNICATIONS
IF15.7
err2020-08-31
err35
errOAAI
errZhu, Zeyu; Surujon, Defne; Ortiz-Marquez, Juan C.; Huo, Wenwen; Isberg, Ralph R.; Bento, Jose; van Opijnen, Tim
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errSave
Topologically correct synthetic reconstruction of pathogen social behavior found during Yersinia growth in deep tissue sites
errELIFE
IF0
err2020-06-16
err3
errOAAI
errClark, Stacie A.; Thibault, Derek; Shull, Lauren M.; Davis, Kimberly M.; Aunins, Emily; van Opijnen, Tim; Isberg, Ralph
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errSave
The vacuole guard hypothesis: how intravacuolar pathogens fight to maintain the integrity of their beloved home
errCURRENT OPINION IN MICROBIOLOGY
IF7.5
err2020-04-01
err16
errOAAI
errAnand, Ila; Choi, Wonyoung; Isberg, Ralph R.
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errSave
Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes
errNATURE COMMUNICATIONS
IF15.7
err2019-12-16
err66
errOAAI
errThibault, Derek; Jensen, Paul A.; Wood, Stephen; Qabar, Christine; Clark, Stacie; Shainheit, Mara G.; Isberg, Ralph R.; van Opijnen, Tim
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errSave
Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model
errBMC GENOMICS
IF3.7
err2019-12-10
err10
errOAAI
errKjellin, Jonas; Pranting, Maria; Bach, Frauke; Vaid, Roshan; Edelbroek, Bart; Li, Zhiru; Hoeppner, Marc P.; Grabherr, Manfred; Isberg, Ralph R.; Hagedorn, Monica; Soderbom, Fredrik
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Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability
errANNUAL REVIEW OF MICROBIOLOGY
IF0
err2019-09-08
err82
PREAI
errGeisinger, Edward; Huo, Wenwen; Hernandez-Bird, Juan; Isberg, Ralph R.
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The iron-regulated vacuolar Legionella pneumophila MavN protein is a transition-metal transporter
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-08-20
err23
errOAAI
errChristenson, Eric T.; Isaac, Dervla T.; Yoshida, Karin; Lipo, Erion; Kim, Jin-Sik; Ghirlando, Rodolfo; Isberg, Ralph R.; Banerjee, Anirban
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errSave
The Landscape of Phenotypic and Transcriptional Responses to Ciprofloxacin in Acinetobacter baumannii: Acquired Resistance Alleles Modulate Drug-Induced SOS Response and Prophage Replication
errMBIO
IF4.7
err2019-06-25
err23
errOAAI
errGeisinger, Edward; Vargas-Cuebas, German; Mortman, Nadav J.; Syal, Sapna; Dai, Yunfei; Wainwright, Elizabeth L.; Lazinski, David; Wood, Stephen; Zhu, Zeyu; Anthony, Jon; van Opijnen, Tim; Isberg, Ralph R.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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H-index: 145 · Papers: 666
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H-index: 143 · Papers: 1.3K
D
Douglas T. Golenbock
H-index: 127 · Papers: 351
J
John J. Mekalanos
H-index: 126 · Papers: 379
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