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SaveUpregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells (vol 14, 11497, 2024)
Liang, Zhuqing; Ralph-Epps, Tyler; Schmidtke, Michael W.; Lazcano, Pablo; Denis, Simone W.; Balazova, Maria; da Rosa, Nevton Teixeira; Chakkour, Mohamed; Hazime, Sanaa; Ren, Mindong; Schlame, Michael; Houtkooper, Riekelt H.; Greenberg, Miriam L.
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SaveUpregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells
Liang, Zhuqing; Ralph-Epps, Tyler; Schmidtke, Michael W.; Lazcano, Pablo; Denis, Simone W.; Balazova, Maria; Darosa, Nevton; Chakkour, Mohamed; Hazime, Sanaa; Ren, Mindong; Schlame, Michael; Houtkooper, Riekelt H.; Greenberg, Miriam L.
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SaveGenetic modifiers modulate phenotypic expression of tafazzin deficiency in a mouse model of Barth syndrome
Wang, Suya; Yazawa, Erika; Keating, Erin M.; Mazumdar, Neil; Hauschild, Alexander; Ma, Qing; Wu, Haiyan; Xu, Yang; Shi, Xu; Strathdee, Douglas; Gerszten, Robert E.; Schlame, Michael; Pu, William T.
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SaveEnrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage
Ilnytska, Olga; Lai, Kimberly; Gorshkov, Kirill; Schultz, Mark L.; Tran, Bruce Nguyen; Jeziorek, Maciej; Kunkel, Thaddeus J.; Azaria, Ruth D.; McLoughlin, Hayley S.; Waghalter, Miriam; Xu, Yang; Schlame, Michael; Altan-Bonnet, Nihal; Zheng, Wei; Lieberman, Andrew P.; Dobrowolski, Radek; Storch, Judith
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SaveCardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function
Li, Yiran; Lou, Wenjia; Raja, Vaishnavi; Denis, Simone; Yu, Wenxi; Schmidtke, Michael W.; Reynolds, Christian A.; Schlame, Michael; Houtkooper, Riekelt H.; Greenberg, Miriam L.
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