Not logged in A human mitofusin 2 mutation can cause mitophagic cardiomyopathy Franco, Antonietta; Li, Jiajia; Kelly, Daniel P.; Hershberger, Ray E.; Marian, Ali J.; Lewis, Renate M.; Song, Moshi; Dang, Xiawei; Schmidt, Alina D.; Mathyer, Mary E.; Edwards, John R.; Strong, Cristina de Guzman; Dorn, Gerald W. Share Save
Breast Cancer Mutations HER2V777L and PIK3CAH1047R Activate the p21-CDK4/6-Cyclin D1 Axis to Drive Tumorigenesis and Drug Resistance Cheng, Xiaoqing; Sun, Yirui; Highkin, Maureen; Vemalapally, Nagalaxmi; Jin, Xiaohua; Zhou, Brandon; Prior, Julie L.; Tipton, Ashley R.; Li, Shunqiang; Iliuk, Anton; Achilefu, Samuel; Hagemann, Ian S.; Edwards, John R.; Bose, Ron Share Save
Older adults with acute severe ulcerative colitis have similar steroid non-response and colectomy rates as younger adults Subhaharan, Deloshaan; Ramaswamy, Pradeep Kakkadasam; Willmann, Laura; Moattar, Hadi; Bhullar, Maneesha; Ishaq, Naveed; Dorrington, Alexander; Shukla, Dheeraj; McIvor, Carolyn; Edwards, John; Mohsen, Waled Share Save
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice Schmitt, Erica G.; Toth, Kelsey A.; Risma, Samuel I.; Kolicheski, Ana; Saucier, Nermina; Berrios, Rafael J. Feliciano; Greenberg, Zev J.; Leiding, Jennifer W.; Bleesing, Jack J.; Thatayatikom, Akaluck; Schuettpelz, Laura G.; Edwards, John R.; Vogel, Tiphanie P.; Cooper, Megan A. Share Save
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Selective sweep for an enhancer involucrin allele identifies skin barrier adaptation out of Africa Mathyer, Mary Elizabeth; Brettmann, Erin A.; Schmidt, Alina D.; Goodwin, Zane A.; Oh, Inez Y.; Quiggle, Ashley M.; Tycksen, Eric; Ramakrishnan, Natasha; Matkovich, Scot J.; Guttman-Yassky, Emma; Edwards, John R.; Strong, Cristina de Guzman Share Save
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A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis Powell, Emily; Shao, Jiansu; Picon, Hector M.; Bristow, Christopher; Ge, Zhongqi; Peoples, Michael; Robinson, Frederick; Jeter-Jones, Sabrina L.; Schlosberg, Christopher; Grzeskowiak, Caitlin L.; Yang, Fei; Wu, Yun; Wistuba, Ignacio; Moulder, Stacy L.; Symmans, William F.; Scott, Kenneth L.; Edwards, John R.; Liang, Han; Heffernan, Timothy P.; Piwnica-Worms, Helen Share Save
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Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer Hiken, J. F.; McDonald, J. I.; Decker, K. F.; Sanchez, C.; Hoog, J.; VanderKraats, N. D.; Jung, K. L.; Akinhanmi, M.; Rois, L. E.; Ellis, M. J.; Edwards, J. R. Share Save
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis Ruhland, Megan K.; Loza, Andrew J.; Capietto, Aude-Helene; Luo, Xianmin; Knolhoff, Brett L.; Flanagan, Kevin C.; Belt, Brian A.; Alspach, Elise; Leahy, Kathleen; Luo, Jingqin; Schaffer, Andras; Edwards, John R.; Longmore, Gregory; Faccio, Roberta; DeNardo, David G.; Stewart, Sheila A. Share Save
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p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer Powell, Emily; Shao, Jiansu; Yuan, Yuan; Chen, Hsiang-Chun; Cai, Shirong; Echeverria, Gloria V.; Mistry, Nipun; Decker, Keith F.; Schlosberg, Christopher; Do, Kim-Anh; Edwards, John R.; Liang, Han; Piwnica-Worms, David; Piwnica-Worms, Helen Share Save
Cellular therapy in combination with cytokines improves survival in a xenograft mouse model of ovarian cancer Ingersoll, Susan B.; Ahmad, Sarfraz; McGann, Hasina C.; Banks, Robert K.; Stavitzski, Nicole M.; Srivastava, Milan; Ali, Ghazanfar; Finkler, Neil J.; Edwards, John R.; Holloway, Robert W. Share Save
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