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Donald C. Sheppard

McGill University

62H-index
225Paper Count
1.7WCitation Count
Published Papers 93
Publication Date
Evaluating the Potential of Galactosaminogalactan as a Diagnostic Target for Invasive Aspergillosis
errMycoses
IF3.1
err2025-10-08
err0
errOAAI
errTakahiro Takazono; Kiyotaka Machida; Francois Le Mauff; Donald C. Sheppard; Satoru Koga; Hotaka Namie; Haretsugu Hishigaki; Junichi Amata; Yuya Ito; Nana Nakada; Tatsuro Hirayama; Masataka Yoshida; Kazuaki Takeda; Naoki Iwanaga; Shotaro Ide; Masato Tashiro; Naoki Hosogaya; Noriho Sakamoto; Keitaro Matsumoto; Katsunori Yanagihara; Yasushi Miyazaki; Koichi Izumikawa; Hiroshi Mukae
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Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide
err2025-05-01
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errOAAI
errVan Loon, Jaime C.; Le Mauff, Francois; Vargas, Mario A.; Gilbert, Stephanie; Pfoh, Roland; Morrison, Zachary A.; Razvi, Erum; Nitz, Mark; Sheppard, Donald C.; Howell, P. Lynne
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Use of a human small airway epithelial cell line to study the interactions of Aspergillus fumigatus with pulmonary epithelial cells
errMSPHERE
IF3.1
err2023-10-24
err1
errOAAI
errLiu, Hong; Lin, Jianfeng; Phan, Quynh T.; Gravelat, Fabrice N.; Sheppard, Donald C.; Filler, Scott G.
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Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence
err2023-02-02
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errOAAI
errRazvi, Erum; Whitfield, Gregory B.; Reichhardt, Courtney; Dreifus, Julia E.; Willis, Alexandra R.; Gluscencova, Oxana B.; Gloag, Erin S.; Awad, Tarek S.; Rich, Jacquelyn D.; da Silva, Daniel Passos; Bond, Whitney; Le Mauff, Francois; Sheppard, Donald C.; Hatton, Benjamin D.; Stoodley, Paul; Reinke, Aaron W.; Boulianne, Gabrielle L.; Wozniak, Daniel J.; Harrison, Joe J.; Parsek, Matthew R.; Howell, P. Lynne
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A B1a-natural IgG-neutrophil axis is impaired in viral- and steroid-associated aspergillosis
err2022-12-07
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PREAI
errSarden, Nicole; Sinha, Sarthak; Potts, Kyle G.; Pernet, Erwan; Hiroki, Carlos H.; Hassanabad, Mortaza F.; Nguyen, Angela P.; Lou, Yuefei; Farias, Raquel; Winston, Brent W.; Bromley, Amy; Snarr, Brendan D.; Zucoloto, Amanda Z.; Andonegui, Graciela; Muruve, Daniel A.; McDonald, Braedon; Sheppard, Donald C.; Mahoney, Douglas J.; Divangahi, Maziar; Rosin, Nicole; Biernaskie, Jeff; Yipp, Bryan G.
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Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling
errMBIO
IF4.7
err2022-08-30
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errOAAI
errDietschmann, Axel; Schruefer, Sebastian; Westermann, Stefanie; Henkel, Fiona; Castiglione, Kirstin; Willebrand, Ralf; Adam, Jasmin; Ruland, Jurgen; Lang, Roland; Sheppard, Donald C.; Esser-von-Bieren, Julia; Radtke, Daniel; Krappmann, Sven; Voehringer, David
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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection
err2022-08-16
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errOAAI
errOstapska, Hanna; Raju, Deepa; Corsini, Rachel; Lehoux, Melanie; Lacdao, Ira; Gilbert, Stephanie; Sivarajah, Piyanka; Bamford, Natalie C.; Baker, Perrin; Gravelat, Fabrice N.; Howell, P. Lynne; Sheppard, Donald C.
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Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells
err2022-07-07
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errOAAI
errPhan, Quynh T.; Solis, Norma, V; Lin, Jianfeng; Swidergall, Marc; Singh, Shakti; Liu, Hong; Sheppard, Donald C.; Ibrahim, Ashraf S.; Mitchell, Aaron P.; Filler, Scott G.
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The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine (vol 5, 502, 2022)
err2022-06-24
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errOAAI
errLe Mauff, Francois; Razvi, Erum; Reichhardt, Courtney; Sivarajah, Piyanka; Parsek, Matthew R.; Howell, P. Lynne; Sheppard, Donald C.
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The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine
err2022-05-26
err36
errOAAI
errLe Mauff, Francois; Razvi, Erum; Reichhardt, Courtney; Sivarajah, Piyanka; Parsek, Matthew R.; Howell, P. Lynne; Sheppard, Donald C.
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An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment
errMBIO
IF4.7
err2022-04-26
err10
errOAAI
errKerkaert, Joshua D.; Le Mauff, Francois; Wucher, Benjamin R.; Beattie, Sarah R.; Vesely, Elisa M.; Sheppard, Donald C.; Nadell, Carey D.; Cramer, Robert A.
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Tackling the emerging threat of antifungal resistance to human health
err2022-03-29
err491
errOAAI
errFisher, Matthew C.; Alastruey-Izquierdo, Ana; Berman, Judith; Bicanic, Tihana; Bignell, Elaine M.; Bowyer, Paul; Bromley, Michael; Brueggemann, Roger; Garber, Gary; Cornely, Oliver A.; Gurr, Sarah J.; Harrison, Thomas S.; Kuijper, Ed; Rhodes, Johanna; Sheppard, Donald C.; Warris, Adilia; White, P. Lewis; Xu, Jianping; Zwaan, Bas; Verweij, Paul E.
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Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions
errMBIO
IF4.7
err2021-10-26
err28
errOAAI
errO'Toole, George A.; Crabbe, Aurelie; Kummerli, Rolf; LiPuma, John J.; Bomberger, Jennifer M.; Davies, Jane C.; Limoli, Dominique; Phelan, Vanessa V.; Bliska, James B.; DePas, William H.; Dietrich, Lars E.; Hampton, Thomas H.; Hunter, Ryan; Khursigara, Cezar M.; Price-Whelan, Alexa; Ashare, Alix; Cramer, Robert A.; Goldberg, Joanna B.; Harrison, Freya; Hogan, Deborah A.; Henson, Michael A.; Madden, Dean R.; Mayers, Jared R.; Nadell, Carey; Newman, Dianne; Prince, Alice; Rivett, Damian W.; Schwartzman, Joseph D.; Schultz, Daniel; Sheppard, Donald C.; Smyth, Alan R.; Spero, Melanie A.; Stanton, Bruce A.; Turner, Paul E.; van der Gast, Chris; Whelan, Fiona J.; Whitaker, Rachel; Whiteson, Katrine; Parsek, Matthew R.
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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases in the Prevention of Experimental Invasive Aspergillosis
errMBIO
IF4.7
err2021-10-26
err10
errOAAI
errOstapska, Hanna; Raju, Deepa; Lehoux, Melanie; Lacdao, Ira; Gilbert, Stephanie; Sivarajah, Piyanka; Bamford, Natalie C.; Baker, Perrin; Thi Tuyet Mai Nguyen; Zacharias, Caitlin A.; Gravelat, Fabrice N.; Howell, P. Lynne; Sheppard, Donald C.
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Marginating transitional B cells modulate neutrophils in the lung during inflammation and pneumonia
err2021-07-27
err17
errOAAI
errPodstawka, John; Sinha, Sarthak; Hiroki, Carlos H.; Sarden, Nicole; Granton, Elise; Labit, Elodie; Kim, Jung Hwan; Andonegui, Graciela; Lou, Yuefei; Snarr, Brendan D.; Sheppard, Donald C.; Rosin, Nicole L.; Biernaskie, Jeff; Yipp, Bryan G.
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The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During Aspergillus fumigatus Airway Infection
err2021-07-12
err14
errOAAI
errRalph, Benjamin A. W. R.; Lehoux, Melanie; Ostapska, Hanna; Snarr, Brendan D. D.; Caffrey-Carr, Alayna K. K.; Fraser, Richard; Saleh, Maya; Obar, Joshua J. J.; Qureshi, Salman T. T.; Sheppard, Donald C. C.
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Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low-Density Lipoproteins and Increasing Their Uptake by Macrophages
err2021-02-16
err41
errOAAI
errDemina, Ekaterina P.; Smutova, Victoria; Pan, Xuefang; Fougerat, Anne; Guo, Tianlin; Zou, Chunxia; Chakraberty, Radhika; Snarr, Brendan D.; Shiao, Tze C.; Roy, Rene; Orekhov, Alexander N.; Miyagi, Taeko; Laffargue, Muriel; Sheppard, Donald C.; Cairo, Christopher W.; Pshezhetsky, Alexey, V
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The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in Aspergillus fumigatus
errMBIO
IF4.7
err2020-12-22
err24
errOAAI
errChen, Yuan; Le Mauff, Francois; Wang, Yan; Lu, Ruiyang; Sheppard, Donald C.; Lu, Ling; Zhang, Shizhu
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