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Matthew P. Frosch

department of neurology, massgeneral institute for neurodegenerative disease, massachusetts general hospital/harvard medical school, charlestown, ma, usa

119H-index
557Paper Count
7.0WCitation Count
Published Papers 241
Publication Date
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Filling in the gap: Hippocampal CA1 neuronal counts and volumes in female cognitive controls
errNeurobiology of Disease
IF5.6
err2025-10-26
err0
errOAAI
errErin-Marie C. Smith; Anne M. Alexander; Kaitlyn H. Watt; Emma W. Rosenblum; Nicole Pihlstrom; Joshua L. Chase; Nathaniel Mercaldo; Elizabeth Conner; André van der Kouwe; Matthew P. Frosch; Jean C. Augustinack
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Novel differentially expressed genes and multiple biological pathways for Alzheimer's disease identified in brain tissue from African American donors
errAlzheimer's & Dementia
IF11.1
err2025-10-08
err0
errOAAI
errMark W. Logue; Adam Labadorf; Nicholas K. O'Neill; Dennis W. Dickson; Brittany N. Dugger; Margaret E. Flanagan; Matthew P. Frosch; Marla Gearing; Lee-Way Jin; Julia Kofler; Richard Mayeux; Ann McKee; Carol A. Miller; Melissa E. Murray; Peter T. Nelson; Richard J. Perrin; Julie A. Schneider; Thor D. Stein; Andrew F. Teich; Katarnut Tobunluepop; Juan C. Troncoso; Shih-Hsiu Wang; Zihan Wang; Benjamin Wolozin; Jesse Mez; Lindsay A. Farrer
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errSave
CAA-related enlarged perivascular spaces are associated with abnormal angioarchitecture in human brain tissue: A key role for white matter atrophy?
errJournal of Cerebral Blood Flow & Metabolism
IF0
err2025-09-08
err0
errOAAI
errMarion Giraud; Dae Hee Yun; Leon P Munting; Kwanghun Chung; Brian J Bacskai; Steven M Greenberg; Matthew P Frosch; Alain Goriely; Susanne J van Veluw; Sylvie Lorthois
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errSave
Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease
errActa Neuropathologica
IF9.3
err2025-06-03
err0
errOAAI
errCharles D. Chen; Erin E. Franklin; Yan Li; Nelly Joseph-Mathurin; Aime L. Burns; Diana A. Hobbs; Austin A. McCullough; Stephanie A. Schultz; Chengjie Xiong; Guoqiao Wang; Mario Masellis; Ging-Yuek Robin Hsiung; Serge Gauthier; Sarah B. Berman; Erik D. Roberson; Lawrence S. Honig; Roger Clarnette; John M. Ringman; James E. Galvin; William Brooks; Kazushi Suzuki; Sandra Black; Johannes Levin; Neelum T. Aggarwal; Mathias Jucker; Matthew P. Frosch; Julia K. Kofler; Charles White; C. Dirk Keene; Jie Chen; Alisha Daniels; Brian A. Gordon; Laura Ibanez; Celeste M. Karch; Jorge Llibre-Guerra; Eric McDade; John C. Morris; Charlene Supnet-Bell; Ricardo F. Allegri; Jae-Hong Lee; Gregory S. Day; Francisco Lopera; Jee Hoon Roh; Peter R. Schofield; Susan Mills; Tammie L. S. Benzinger; Randall J. Bateman; Richard J. Perrin
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Single- cell elderly blood-CSF atlas implicates peripherally influenced immune dysregulation in normal pressure hydrocephalus
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2025-05-05
err0
errOAAI
errDuy, Phan Q.; Kiziltug, Emre; Greenberg, Ana B. W.; Mehta, Neel H.; Hao, Le T.; Fortes, Carla; Mullany, Susan; Fan, Baojian; Manichaikul, Ani; Teich, Andrew F.; Chan, Diane; Alper, Seth L.; Hyman, Bradley T.; Arnold, Steven E.; Mckhann, Guy M.; Frosch, Matthew P.
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errSave
Collision tumor, a metastatic melanoma within a meningioma: a case report
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2025-03-12
err0
errOAAI
errYamazawa, E; Cahill, DP; Frosch, MP; Brastianos, PK; Sullivan, RJ
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errSave
Locus coeruleus tau validates and informs high-resolution MRI in aging and at earliest Alzheimer's pathology stages
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2025-02-28
err0
errOAAI
errHary, Alexander T.; Chadha, Smriti; Mercaldo, Nathaniel; Smith, Erin-Marie C.; van der Kouwe, Andre J. W.; Fischl, Bruce; Mount, Christopher; Kozanno, Liana; Frosch, Matthew P.; Augustinack, Jean C.
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errSave
Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes
errJOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
IF3
err2024-12-04
err0
errOAAI
errSepulveda-Falla, Diego; Villegas Lanau, Carlos Andres; White Iii, Charles; Serrano, Geidy E.; Acosta-Uribe, Juliana; Mejia-Cupajita, Barbara; Villalba-Moreno, Nelson David; Lu, Pinzhang; Glatzel, Markus; Kofler, Julia K.; Ghetti, Bernardino; Frosch, Matthew P.; Restrepo, Francisco Lopera; Kosik, Kenneth S.; Beach, Thomas G.
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Neuron collinearity differentiates human hippocampal subregions: a validated deep learning approach
errBRAIN COMMUNICATIONS
IF4.5
err2024-09-03
err0
errOAAI
errOltmer, Jan; Williams, Emily M.; Groha, Stefan; Rosenblum, Emma W.; Roy, Jessica; Llamas-Rodriguez, Josue; Perosa, Valentina; Champion, Samantha N.; Frosch, Matthew P.; Augustinack, Jean C.
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errSave
Annexin A11 mutations are associated with nuclear envelope dysfunction in vivo and in human tissues
errBRAIN
IF11.7
err2024-07-11
err1
PREAI
errMarchica, Valentina; Biasetti, Luca; Barnard, Jodi; Li, Shujing; Nikolaou, Nikolas; Frosch, Matthew P.; Lucente, Diane E.; Eldaief, Mark; King, Andrew; Fanto, Manolis; Troakes, Claire; Houart, Corinne; Smith, Bradley N.
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errSave
Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology
errELIFE
IF0
err2024-06-19
err2
errOAAI
errGazula, Harshvardhan; Tregidgo, Henry F. J.; Billot, Benjamin; Balbastre, Yael; Williams-Ramirez, Jonathan; Herisse, Rogeny; Deden-Binder, Lucas J.; Casamitjana, Adria; Melief, Erica J.; Latimer, Caitlin S.; Kilgore, Mitchell D.; Montine, Mark; Robinson, Eleanor; Blackburn, Emily; Marshall, Michael S.; Connors, Theresa R.; Oakley, Derek H.; Frosch, Matthew P.; Young, Sean, I; Van Leemput, Koen; Dalca, Adrian, V; Fischl, Bruce; MacDonald, Christine L.; Keene, C. Dirk; Hyman, Bradley T.; Iglesias, Juan E.
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errSave
β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains
errJOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
IF3
err2024-06-14
err1
errOAAI
errOakley, Derek H.; Chung, Mirra; Abrha, Sara; Hyman, Bradley T.; Frosch, Matthew P.
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errSave
Entorhinal vessel density correlates with phosphorylated tau and TDP-43 pathology
errALZHEIMERS & DEMENTIA
IF11.1
err2024-06-14
err0
errOAAI
errLlamas Rodriguez, Josue; van der Kouwe, Andre J. W.; Oltmer, Jan; Rosenblum, Emma; Mercaldo, Nathaniel; Fischl, Bruce; Marshall, Michael; Frosch, Matthew P.; Augustinack, Jean C.
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errSave
α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden
errALZHEIMERS & DEMENTIA
IF11.1
err2024-04-26
err3
errOAAI
errLevin, Johannes; Baiardi, Simone; Quadalti, Corinne; Rossi, Marcello; Mammana, Angela; Voeglein, Jonathan; Bernhardt, Alexander; Perrin, Richard J.; Jucker, Mathias; Preische, Oliver; Hofmann, Anna; Hoeglinger, Guenter U.; Cairns, Nigel J.; Franklin, Erin E.; Chrem, Patricio; Cruchaga, Carlos; Berman, Sarah B.; Chhatwal, Jasmeer P.; Daniels, Alisha; Day, Gregory S.; Ryan, Natalie S.; Goate, Alison M.; Gordon, Brian A.; Huey, Edward D.; Ibanez, Laura; Karch, Celeste M.; Lee, Jae-Hong; Llibre-Guerra, Jorge; Lopera, Francisco; Masters, Colin L.; Morris, John C.; Noble, James M.; Renton, Alan E.; Roh, Jee Hoon; Frosch, Matthew P.; Keene, C. Dirk; Mclean, Catriona; Sanchez-Valle, Raquel; Schofield, Peter R.; Supnet-Bell, Charlene; Xiong, Chengjie; Giese, Armin; Hansson, Oskar; Bateman, Randall J.; Mcdade, Eric; Parchi, Piero
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Radical surgical resection with molecular margins is associated with improved survival in IDH wild-type glioblastoma
errNEURO-ONCOLOGY
IF13.4
err2024-04-06
err0
PREAI
errMassaad, Elie; Smith, William J.; Bradley, Joseph; Esposito, Eric; Gupta, Mihir; Burns, Evan; Burns, Ryan; Velarde, Jose K.; Berglar, Inka K.; Gupta, Rajiv; Martinez-Lage, Maria; Dietrich, Jorg; Lennerz, Jochen K.; Dunn, Gavin P.; Jones, Pamela S.; Choi, Bryan D.; Kim, Albert E.; Frosch, Matthew; Barker, Fred G.; Curry, William T.; Carter, Bob S.; Nahed, Brian, V; Cahill, Daniel P.; Shankar, Ganesh M.
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errSave
Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau
errACTA NEUROPATHOLOGICA
IF9.3
err2024-04-01
err2
errOAAI
errWachter, Astrid; Woodbury, Maya E.; Lombardo, Sylvia; Abdourahman, Aicha; Wuest, Carolin; Mcglame, Emily; Pastika, Timothy; Tamm, Joseph; Romanul, Nandini; Yanamandra, Kiran; Bennett, Rachel; Lin, Gen; Kwon, Taekyung; Liao, Fan; Klein, Corinna; Grinberg, Yelena; Jaisa-aad, Methasit; Li, Huan; Frosch, Matthew. P.; Kummer, Markus P.; Das, Sudeshna; Dellovade, Tammy; Karran, Eric H.; Langlois, Xavier; Ried, Janina S.; Serrano-Pozo, Alberto; Talanian, Robert V.; Biber, Knut; Hyman, Bradley T.
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errSave
Head-to-head comparison of [18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases
errACTA NEUROPATHOLOGICA
IF9.3
err2024-01-27
err2
errOAAI
errAguero, Cinthya; Dhaynaut, Maeva; Amaral, Ana C.; Moon, S-H; Neelamegam, Ramesh; Scapellato, Margaret; Carazo-Casas, Carlos; Kumar, Sunny; El Fakhri, Georges; Johnson, Keith; Frosch, Matthew P.; Normandin, Marc D.; Gomez-Isla, Teresa
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errSave
Role of Basal Forebrain Neurons in Adrenomyeloneuropathy in Mice and Humans
errANNALS OF NEUROLOGY
IF7.7
err2023-12-26
err6
errOAAI
errGong, Yi; Laheji, Fiza; Berenson, Anna; Li, Yedda; Moser, Ann; Qian, April; Frosch, Matthew; Sadjadi, Reza; Hahn, Ryan; Maguire, Casey A.; Eichler, Florian
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A cellular resolution atlas of Broca's area
errSCIENCE ADVANCES
IF12.5
err2023-10-13
err9
errOAAI
errCostantini, Irene; Morgan, Leah; Yang, Jiarui; Balbastre, Yael; Varadarajan, Divya; Pesce, Luca; Scardigli, Marina; Mazzamuto, Giacomo; Gavryusev, Vladislav; Castelli, Filippo Maria; Roffilli, Matteo; Silvestri, Ludovico; Laffey, Jessie; Raia, Sophia; Varghese, Merina; Wicinski, Bridget; Chang, Shuaibin; Chen, Ichun Anderson; Wang, Hui; Cordero, Devani; Vera, Matthew; Nolan, Jackson; Nestor, Kimberly; Mora, Jocelyn; Iglesias, Juan Eugenio; Garcia Pallares, Erendira; Evancic, Kathryn; Augustinack, Jean C.; Fogarty, Morgan; Dalca, Adrian V.; Frosch, Matthew P.; Magnain, Caroline; Frost, Robert; van der Kouwe, Andre; Chen, Shih-Chi; Boas, David A.; Pavone, Francesco Saverio; Fischl, Bruce; Hof, Patrick R.
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errSave
Reply: Soluble oligomers or insoluble fibrils?
errACTA NEUROPATHOLOGICA
IF9.3
err2023-09-21
err3
errOAAI
errde Gerando, Anastasie Mate; Quittot, Noe; Frosch, Matthew P.; Hyman, Bradley T.
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Research Directions

No research directions
Co-authors
Cooperation Journals
J
John Q. Trojanowski
H-index: 255 · Papers: 1.8K
C
Cornelia M. van Duijn
H-index: 238 · Papers: 1.9K
A
André G. Uitterlinden
H-index: 234 · Papers: 2.0K
D
Dennis W. Dickson
H-index: 218 · Papers: 2.3K
E
Eric Boerwinkle
H-index: 215 · Papers: 2.0K
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