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SaveThe anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity
Wakasa, Takeshi; Nonaka, Kentaro; Harada, Akihito; Ohkawa, Yasuyuki; Kikutake, Chie; Suyama, Mikita; Kobunai, Takashi; Tsunekuni, Kenta; Matsuoka, Kazuaki; Kataoka, Yuki; Ochiiwa, Hiroaki; Miyadera, Kazutaka; Sagara, Takeshi; Oki, Eiji; Ohdo, Shigehiro; Maehara, Yoshihiko; Iimori, Makoto; Kitao, Hiroyuki Share Save Mutational spectrum of TP53 gene correlates with nivolumab treatment efficacy in advanced gastric cancer (TP53MUT study)Ando, Koji; Nakamura, Yoshiaki; Kitao, Hiroyuki; Shimokawa, Mototsugu; Kotani, Daisuke; Bando, Hideaki; Nishina, Tomohiro; Yamada, Takanobu; Yuki, Satoshi; Narita, Yukiya; Hara, Hiroki; Ohta, Takashi; Esaki, Taito; Hamamoto, Yasuo; Kato, Ken; Yamamoto, Yoshiyuki; Minashi, Keiko; Ohtsubo, Koushiro; Izawa, Naoki; Kawakami, Hisato; Kato, Takeshi; Satoh, Taroh; Okano, Naohiro; Tsuji, Akihito; Yamazaki, Kentaro; Yoshino, Takayuki; Maehara, Yoshihiko; Oki, Eiji Share Save Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signalingTaniguchi, Koji; Kohno, Ri-ichiro; Ayada, Toranoshin; Kato, Reiko; Ichiyama, Kenji; Morisada, Tohru; Oike, Yuichi; Yonemitsu, Yoshikazu; Maehara, Yoshihiko; Yoshimura, Akihiko Share Save Share Save Share Save Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical TrialMatsumoto, Takuya; Yoshino, Shinichiro; Furuyama, Tadashi; Morisaki, Koichi; Nakano, Kaku; Koga, Jun-ichiro; Maehara, Yoshihiko; Komori, Kimihiro; Mori, Masaki; Egashira, Kensuke Share Save Effects of an elemental diet to reduce adverse events in patients with esophageal cancer receiving docetaxel/cisplatin/5-fluorouracil: a phase III randomized controlled trial-EPOC 2 (JFMC49-1601-C5)Tanaka, Y.; Takeuchi, H.; Nakashima, Y.; Nagano, H.; Ueno, T.; Tomizuka, K.; Morita, S.; Emi, Y.; Hamai, Y.; Hihara, J.; Saeki, H.; Oki, E.; Kunisaki, C.; Otsuji, E.; Baba, H.; Matsubara, H.; Maehara, Y.; Kitagawa, Y.; Yoshida, K. Share Save Expression of CD44 variant 9 induces chemoresistance of gastric cancer by controlling intracellular reactive oxygen spices accumulation (May, 10.1007/s10120-021-01194-5, 2021)Jogo, Tomoko; Oki, Eiji; Nakanishi, Ryota; Ando, Koji; Nakashima, Yuichiro; Kimura, Yasue; Saeki, Hiroshi; Oda, Yoshinao; Maehara, Yoshihiko; Mori, Masaki Share Save Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I InhibitorsAndo, Koji; Ozonoff, Al; Lee, Shin-Yin; Voisine, Michael; Parker, Julian-Taylor; Nakanishi, Ryota; Nishimura, Sho; Yang, Jing; Grace, Zhao; Tran, Ben; Diefenbach, Thomas J.; Maehara, Yoshihiko; Yasui, Hiroshi; Irino, Tomoyuki; Salgia, Ravi; Terashima, Masanori; Gibbs, Peter; Ramanathan, Ramesh K.; Oki, Eiji; Mori, Masaki; Kulke, Matthew; Hartshorn, Kevan; Bharti, Ajit Share Save Expression of CD44 variant 9 induces chemoresistance of gastric cancer by controlling intracellular reactive oxygen spices accumulationJogo, Tomoko; Oki, Eiji; Nakanishi, Ryota; Ando, Koji; Nakashima, Yuichiro; Kimura, Yasue; Saeki, Hiroshi; Oda, Yoshinao; Maehara, Yoshihiko; Mori, Masaki Share Save Phase II study of trifluridine/tipiracil plus bevacizumab by RAS mutation status in patients with metastatic colorectal cancer refractory to standard therapies: JFMC51-1702-C7Takahashi, T.; Yamazaki, K.; Oki, E.; Shiozawa, M.; Mitsugi, K.; Makiyama, A.; Nakamura, M.; Ojima, H.; Kagawa, Y.; Matsuhashi, N.; Okuda, H.; Asayama, M.; Yuasa, Y.; Shimada, Y.; Manaka, D.; Watanabe, J.; Oba, K.; Yoshino, T.; Yoshida, K.; Maehara, Y. Share Save Preoperative prognostic nutritional index level is associated with tumour-infiltrating lymphocyte status in patients with surgically resected lung squamous cell carcinomaKitahara, Hirokazu; Shoji, Fumihiro; Akamine, Takaki; Kinoshita, Fumihiko; Haratake, Naoki; Takenaka, Tomoyoshi; Tagawa, Tetsuzo; Sonoda, Takashi; Shimokawa, Mototsugu; Maehara, Yoshihiko; Mori, Masaki Share Save Oxaliplatin-based adjuvant chemotherapy duration (3 versus 6 months) for high-risk stage II colon cancer: the randomized phase III ACHIEVE-2 trialYamazaki, K.; Yamanaka, T.; Shiozawa, M.; Manaka, D.; Kotaka, M.; Gamoh, M.; Shiomi, A.; Makiyama, A.; Munemoto, Y.; Rikiyama, T.; Fukunaga, M.; Ueki, T.; Shitara, K.; Shinkai, H.; Tanida, N.; Oki, E.; Sunami, E.; Ohtsu, A.; Maehara, Y.; Yoshino, T. Share Save Share Save Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cellsInada, Hiroki; Udono, Miyako; Matsuda-Ito, Kanae; Horisawa, Kenichi; Ohkawa, Yasuyuki; Miura, Shizuka; Goya, Takeshi; Yamamoto, Junpei; Nagasaki, Masao; Ueno, Kazuko; Saitou, Daisuke; Suyama, Mikita; Maehara, Yoshihiko; Kumamaru, Wataru; Ogawa, Yoshihiro; Sekiya, Sayaka; Suzuki, Atsushi Share Save De novo hepatocellular carcinoma in living donor liver grafts: A Japanese multicenter experienceGoto, Ryoichi; Kosai-Fujimoto, Yukiko; Yagi, Shintaro; Kobayashi, Tsuyoshi; Akamatsu, Nobuhisa; Shimamura, Tsuyoshi; Imura, Satoru; Ogiso, Satoshi; Mizuno, Shugo; Takatsuki, Mitsuhisa; Fukuhara, Takasuke; Kanto, Tatsuya; Eguchi, Susumu; Yanaga, Katsuhiko; Ogura, Yasuhiro; Fukumoto, Takumi; Shimada, Mitsuo; Hasegawa, Kiyoshi; Ohdan, Hideki; Uemoto, Shinji; Soejima, Yuji; Ikegami, Toru; Yoshizumi, Tomoharu; Taketomi, Akinobu; Maehara, Yoshihiko Share Save DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 StatusKataoka, Yuki; Iimori, Makoto; Fujisawa, Ryo; Morikawa-Ichinose, Tomomi; Niimi, Shinichiro; Wakasa, Takeshi; Saeki, Hiroshi; Oki, Eiji; Miura, Daisuke; Tsurimoto, Toshiki; Maehara, Yoshihiko; Kitao, Hiroyuki Share Save Effects of elemental diet for gastrointestinal adverse events in patients with esophageal cancer receiving docetaxel/cisplatin/5-fluorouracil (EPOC 2 study: JFMC49-1601-C5): A phase III randomized controlled trialTakeuchi, H.; Tanaka, Y.; Nakashima, Y.; Otsuji, E.; Nagano, H.; Matsubara, H.; Baba, H.; Emi, Y.; Oki, E.; Ueno, T.; Tomizuka, K.; Morita, S.; Kunisaki, C.; Hihara, J.; Saeki, H.; Hamai, Y.; Maehara, Y.; Kitagawa, Y.; Yoshida, K. Share Save Prognostic effect of postoperative serum carcinoembryonic antigen (CEA) combined with T4 versus T3 tumors in patients with high-risk stage 2 colon cancer: ACHIEVE-2 phase III randomized clinical trialShiomi, A.; Shiozawa, M.; Manaka, D.; Kotaka, M.; Sakamoto, Y.; Makiyama, A.; Munemoto, Y.; Rikiyama, T.; Fukunaga, M.; Ueki, T.; Shitara, K.; Shinkai, H.; Tanida, N.; Oki, E.; Yamanaka, T.; Sunami, E.; Yamazaki, K.; Ohtsu, A.; Maehara, Y.; Yoshino, T. Share Save 
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