Not logged in Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma Wirth, Lena Vanessa; Hugaboom, Miya B.; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; El Ahmar, Nourhan; Matar, Sayed; Savla, Varunika; Choueiri, Toni; Denize, Thomas; West, Destiny; Mcdermott, David F.; Plimack, Elizabeth R.; Sosman, Jeffrey; Haas, Naomi; Hurwitz, Michael E.; Hammers, Hans; Stein, Mark; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine J.; Braun, David Share Save
CD163+Tumor-Associated macrophages and clinical outcomes to First-Line nivolumab therapy in patients with metastatic clear cel renal cell carcinoma: insights from the HCRN GU16-260 trial Simsek, Berkay; Paul, Morgan A.; Xie, Wanling; El Ahmar, Nourhan; Matar, Sayed; Laimon, Yasmin Nabil; RobertiDe Oliveira, Gabriel; Mohanna, Razan; Delcea, Andrew; Choueri, Toni; Braun, David; Sun, Maxine; Haas, Naomi B.; Hammers, Hans J.; Bilen, Mehmet; Stein, Mark N.; Sosman, Jeffrey A.; Freeman, Gordon J.; Wu, Catherine; Mcdermott, David; Atkins, Michael B.; Signoretti, Sabina Share Save
Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma Wirth, Lena; Hugaboom, Miya; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; El Ahmar, Nourhan; Matar, Sayed; Savla, Varunika; Choueri, Toni; Denize, Thomas; West, Destiny; Mcdermott, David; Plimack, Elizabeth; Sosman, Jeffrey A.; Haas, Naomi B.; Hurwitz, Michael; Hammers, Hans J.; Stein, Mark N.; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine; Braun, David Share Save
Tertiary Lymphoid Structures Predict Response to First-Line Nivolumab Therapy in Advanced Renal Cell Carcinoma: Findings from the HCRN GU16-260 Clinical Trial El Ahmar, Nourhan; Simsek, Berkay; Jegede, Opeyemi; Matar, Sayed; Savla, Varunika; Laimon, Yasmin; Mohanna, Razan; De Oliveira, Gabriel Roberti; Sheshdeh, Aseman Baghari; Delcea, Andrew; Paul, Morgan; Choueiri, Toni; Xie, Wanling; Freeman, Gordon; Braun, David; Haas, Naomi Balzer; Hammers, Hans; Bilen, Mehmet; Stein, Mark; Sosman, Jeffrey; Wu, Catherine; Mcdermott, David; Atkins, Michael; Signoretti, Sabina Share Save
Management of Immunotherapy-Related Toxicities, Version 2.2024 Featured Updates to the NCCN Guidelines Thompson, John A.; Schneider, Bryan J.; Brahmer, Julie; Abu Zaid, Mohammad; Achufusi, Amaka; Armand, Philippe; Berkenstock, Meghan K.; Bermas, Bonnie; Braaten, Tawnie; Budde, Lihua E.; Chokshi, Saurin; Crees, Zachary D.; Davies, Marianne; Deng, Changchun; Gesthalter, Yaron; Jain, Michael; Jain, Prantesh; Jallouk, Andrew; Kaffenberger, Benjamin H.; Khalil, Maya; Lechner, Melissa G.; Li, Tianhong; Marr, Alissa; Mcgettigan, Suzanne; Mcpherson, Jordan; Medina, Theresa; Mohindra, Nisha A.; Olszanski, Anthony J.; Oluwole, Olalekan; Patel, Sandip P.; Prosek, Jason; Reddy, Sunil; Reid, Pankti; Ryan, John; Ryder, Mabel; Salman, Huda; Santomasso, Bianca; Shofer, Scott; Sosman, Jeffrey A.; Wang, Yinghong; Zaha, Vlad G.; Zucker, Stephen; Lyons, Megan; Awotiwon, Ajibola; Hang, Lisa Share Save
Combined programmed cell death protein 1 and cytotoxic T-lymphocyte associated protein 4 blockade in an international cohort of patients with acral lentiginous melanoma Mcgillivray, Erin; Ashouri, Karam; Chatziioannou, Eftychia; Gallegos, Jesus Antonio Ocejo; Zarka, Jabra; Kechter, Jacob; Hwang, Angelina S.; Zhang, Kevin; Barros, Milton; Yeh, Justin; Okazaki, Ian; Crocker, Andrew B.; Maeda, Takuya; Park, Soo J.; Choi, Jacob; Andreoli, Mia; Darwish, Tarneem; Savage, David J.; Kim, Kevin B.; Gupta, Jayant; Shen, James; Shirai, Keisuke; Choi, April; Pai, Lori; Vazquez, Vinicius de Lima; Moser, Justin; Amaral, Teresa; Aya, Leonel F. Hernandez; Lutzky, Jose; Najjar, Yana G.; Costello, Collin M.; Mangold, Aaron R.; Bhatia, Shailender; Gibney, Geoffrey T.; Farma, Jeffrey M.; Daniels, Gregory A.; Sosman, Jeffrey; Chandra, Sunandana; Mangla, Ankit; Bollin, Kathryn; Possik, Patricia Abrao; Robles-Espinoza, Carla Daniela; Ito, Fumito; In, Gino K. Share Save
Preexisting Skin-Resident CD8 and γδ T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy Reinstein, Zachary Z.; Zhang, Yue; Ospina, Oscar E.; Nichols, Matt D.; Chu, Victoria A.; Pulido, Alvaro de Mingo; Prieto, Karol; Nguyen, Jonathan V.; Yin, Rui; Segura, Carlos Moran; Usman, Ahmed; Sell, Brittney; Ng, Spencer; de la Iglesia, Janis V.; Chandra, Sunandana; Sosman, Jeffrey A.; Cho, Raymond J.; Cheng, Jeffrey B.; Ivanova, Ellie; Koralov, Sergei B.; Slebos, Robbert J. C.; Chung, Christine H.; Khushalani, Nikhil I.; Messina, Jane L.; Sarnaik, Amod A.; Zager, Jonathan S.; Sondak, Vernon K.; Vaske, Charles; Kim, Sungjune; Brohl, Andrew S.; Mi, Xinlei; Pierce, Brian G.; Wang, Xuefeng; Fridley, Brooke L.; Tsai, Kenneth Y.; Choi, Jaehyuk Share Save
SLAMF7+CD8+T cells exhibit decreased anti-tumor responses in renal cell carcinoma Wirth, Lena; Hugaboom, Miya; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Mcdermott, David; Plimack, Elizabeth; Sosman, Jeffrey; Haas, Naomi; Hurwitz, Michael; Hammers, Hans; Signoretti, Sabina; Atkins, Michael; Wu, Catherine; Braun, David Share Save
Treatment-free survival outcomes from the phase II study of nivolumab and salvage nivolumab/ipilimumab in advanced clear cell renal cell carcinoma (HCRN GU16-260-Cohort A) Atkins, Michael B.; Jegede, Opeyemi A.; Haas, Naomi B.; Mcdermott, David F.; Bilen, Mehmet A.; Stein, Mark; Sosman, Jeffrey; Alter, Robert; Plimack, Elizabeth R.; Ornstein, Moshe C.; Hurwitz, Michael; Peace, David J.; Einstein, David; Catalano, Paul J.; Hammers, Hans; Regan, Meredith M. Share Save
Biopsy analysis of trial S1616: Ipilimumab plus nivolumab versus ipilimumab alone in patients with anti-PD-1 refractory melanoma Campbell, Katie M.; Bustami, Zaid; Chen, Daniel G.; Medina, Egmidio; Gonzalez, Cynthia R.; Aldeen, Nataly Naser; Baselga-Carretero, Ignacio; Vega-Crespo, Agustin; Maxey, Jessica; Chen, Jia M.; Kuklinski, Lawrence F.; Kendra, Kari L.; Chmielowski, Bartosz; Thach-Giao Truong; Khushalani, Nikhil I.; Collichio, Frances; Ikeguchi, Alexandra; Victor, Adrienne I.; Margolin, Kim; Sosman, Jeffrey A.; Patel, Sapna P.; Hu-Lieskovan, Siwen; Moon, James; Bellasea, Shay; Wells, Daniel K.; Spencer, Christine N.; Thompson, Marshall A.; Wu, Michael; Scumpia, Philip O.; VanderWalde, Ari; Ribas, Antoni Share Save
Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach Tran, Steven D.; Lin, Jean; Galvez, Carlos; Rasmussen, Luke V.; Pacheco, Jennifer; Perottino, Giovanni M.; Rahbari, Kian J.; Miller, Charles D.; John, Jordan D.; Theros, Jonathan; Vogel, Kelly; Dinh, Patrick V.; Malik, Sara; Ramzan, Umar; Tegtmeyer, Kyle; Mohindra, Nisha; Johnson, Jodi L.; Luo, Yuan; Kho, Abel; Sosman, Jeffrey; Walunas, Theresa L. Share Save
CD8+T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4 Chen, Siqi; Fan, Jie; Xie, Ping; Ahn, Jihae; Fernandez, Michelle; Billingham, Leah K.; Miska, Jason; Wu, Jennifer D.; Wainwright, Derek A.; Fang, Deyu; Sosman, Jeffrey A.; Wan, Yong; Zhang, Yi; Chandel, Navdeep S.; Zhang, Bin Share Save
Kidney Cancer, Version 2.2024 Featured Updates to the NCCN Guidelines Motzer, Robert J.; Jonasch, Eric; Agarwal, Neeraj; Alva, Ajjai; Bagshaw, Hilary; Baine, Michael; Beckermann, Kathryn; Carlo, Maria I.; Choueiri, Toni K.; Costello, Brian A.; Derweesh, Ithaar H.; Desai, Arpita; Ged, Yasser; George, Saby; Gore, John L.; Gunn, Andrew; Haas, Naomi; Johnson, Michael; Kapur, Payal; King, Jennifer; Kyriakopoulos, Christos; Lam, Elaine T.; Lara, Primo N.; Lau, Clayton; Lewis, Bryan; Madoff, David C.; Manley, Brandon; Michaelson, M. Dror; Mortazavi, Amir; Ponsky, Lee; Ramalingam, Sundhar; Shuch, Brian; Smith, Zachary L.; Sosman, Jeffrey; Sweis, Randy; Zibelman, Matthew; Schonfeld, Ryan; Stein, MaryElizabeth; Gurski, Lisa A. Share Save
Summary of Research: Adjuvant Nivolumab Plus Ipilimumab Versus Placebo for Localized Renal Cell Carcinoma After Nephrectomy (CheckMate 914): A Double-Blind, Randomized, Phase 3 Trial Motzer, Robert J.; Russo, Paul; Gruenwald, Viktor; Tomita, Yoshihiko; Zurawski, Bogdan; Parikh, Omi; Buti, Sebastiano; Barthelemy, Philippe; Goh, Jeffrey C.; Ye, Dingwei; Lingua, Alejo; Lattouf, Jean-Baptiste; Albiges, Laurence; George, Saby; Shuch, Brian; Sosman, Jeffrey; Staehler, Michael; Vazquez Estevez, Sergio; Simsek, Burcin; Spiridigliozzi, Julia; Chudnovsky, Aleksander; Bex, Axel Share Save
Ipilimumab with or without nivolumab in PD-1 or PD-L1 blockade refractory metastatic melanoma: a randomized phase 2 trial VanderWalde, Ari; Bellasea, Shay L.; Kendra, Kari L.; Khushalani, Nikhil I.; Campbell, Katie M.; Scumpia, Philip O.; Kuklinski, Lawrence F.; Collichio, Frances; Sosman, Jeffrey A.; Ikeguchi, Alexandra; Victor, Adrienne I.; Truong, Thach-Giao; Chmielowski, Bartosz; Portnoy, David C.; Chen, Yuanbin; Margolin, Kim; Bane, Charles; Dasanu, Constantin A.; Johnson, Douglas B.; Eroglu, Zeynep; Chandra, Sunandana; Medina, Egmidio; Gonzalez, Cynthia R.; Baselga-Carretero, Ignacio; Vega-Crespo, Agustin; Garcilazo, Ivan Perez; Sharon, Elad; Hu-Lieskovan, Siwen; Patel, Sapna P.; Grossmann, Kenneth F.; Moon, James; Wu, Michael C.; Ribas, Antoni Share Save
T cell clonotype expansion is common in advanced renal cell carcinoma but is not associated with altered response to PD-1 blockade Hugaboom, Miya B.; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas R.; Wirth, Lena; Kyrysyuk, Sasha; McDermott, David F.; Plimack, Elizabeth R.; Sosman, Jeffrey A.; Haas, Naomi B.; Hurwitz, Michael E.; Hammers, Hans J.; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine J.; Braun, David A.; Street, Kelly Share Save
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The Great Debate at Melanoma Bridge 2022, Naples, December 1st-3rd, 2022 Ascierto, Paolo A. A.; Blank, Christian; Eggermont, Alexander M. M.; Garbe, Claus; Gershenwald, Jeffrey E. E.; Hamid, Omid; Hauschild, Axel; Luke, Jason J. J.; Mehnert, Janice M. M.; Sosman, Jeffrey A. A.; Tawbi, Hussein A. A.; Mandala, Mario; Testori, Alessandro; Caraco, Corrado; Osman, Iman; Puzanov, Igor Share Save
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