Not logged in Advancing CNS tumor diagnostics with expanded DNA methylation-based classification Sill, Martin; Schrimpf, Daniel; Patel, Areeba; Sturm, Dominik; Jager, Natalie; Sievers, Philipp; Wick, Wolfgang; von Deimling, Andreas; Capper, David; Pfister, Stefan M.; Jones, David T. W.; Sahm, Felix Share Save
A cycling, progenitor-like cell population at the base of atypical teratoid rhabdoid tumor subtype differentiation trajectories Blanco-Carmona, Enrique; Paassen, Irene; He, Jiayou; Demartino, Jeff; Bullesbach, Annette; Anderson, Nadia; Buhl, Juliane L.; Federico, Aniello; Mauermann, Monika; Brok, Mariel; Straathof, Karin; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew M.; Foreman, Nicholas K.; Shaw, Mckenzie; Fruhwald, Michael C.; Korshunov, Andrey; Hasselblatt, Martin; Thomas, Christian; Franke, Niels; Kranendonk, Mariette E. G.; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella G.; Kool, Marcel; Drost, Jarno Share Save
MOLECULAR SUBTYPES, CLINICAL CHARACTERISTICS, AND THERAPEUTIC IMPLICATIONS FOR CNS TUMORS WITH BCOR/BCORL1 FUSION/INTERNAL TANDEM DUPLICATION Gojo, Johannes; Federico, Aniello; Geisemeyer, Neal; Schmitt-Hoffner, Felix; Mauermann, Monika; Sill, Martin; Bruckner, Katharina; Korshunov, Andrey; Stichel, Damian; Capper, David; Tauziede-Espariat, Arnault; Varlet, Pascale; Aldape, Kenneth; Abdullaev, Zied; Donson, Andrew M.; Pahnke, Jens; Schueller, Ulrich; Galbraith, Kristyn; Snuderl, Matija; Alexandrescu, Sanda; Filbin, Mariella; Gramatzki, Dorothee; Urbanic-Purkart, Tadeja; Ziad, Fouzia; Toledano, Helen; Kerl, Kornelius; Hasselblatt, Martin; Papusha, Ludmila; Brandner, Sebastian; Lastowska, Maria; Miele, Evelina; v d Lugt, Jasper; Bunt, Jens; Kramm, Christof; Andre, Nicolas; Appay, Romain; Bouchoucha, Yassine; Hansford, Jordan; Zapotocky, Michal; Kranendonk, Mariette E.; Nobusawa, Sumihito; Solomon, David; Haberler, Christine; Jones, Barbara; Sturm, Dominik; Sahm, Felix; Jaeger, Natalie; Pfister, Stefan M.; v Hoff, Katja; Kool, Marcel Share Save
GENE REGULATORY NETWORK LANDSCAPE OF GROUP 3/4 MEDULLOBLASTOMA Joshi, Piyush; Stelzer, Tamina; Okonechnikov, Konstantin; Sarropoulos, Ioannis; Sepp, Mari; Pour-Jamnani, Mischan, V; Rademacher, Anne; Yamada-Saito, Tetsuya; Schneider, Celine; Schmidt, Julia; Schaefer, Philipp; Leiss, Kevin; Bortolomeazzi, Michele; Mallm, Jan-Philipp; da Silva, Patricia B. G.; Statz, Britta; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Milde, Till; Pajtler, Kristian; van Tilburg, Cornelis M.; Witt, Olaf; Rippe, Karsten; Korshunov, Andrey; Jones, David T. W.; Hovestadt, Volker; Northcott, Paul A.; Thongjuea, Supat; Jaeger, Natalie; Kaessmann, Henrik; Pfister, Stefan M.; Kutscher, Lena M. Share Save
ACCELERATING COMPREHENSIVE CNS TUMOR MOLECULAR DIAGNOSTICS WITH RAPID-CNS2 AND MNP-FLEX: A PROSPECTIVE MULTI-CENTER VALIDATION Patel, Areeba J.; Goebel, Kirsten; Hinz, Felix; Dogan, Helin; Schrimpf, Daniel; Goeller, Pauline; Leske, Henning; Halldorsson, Skarpheoinn; Fox, Graeme; Deacon, Simon; Paine, Simon; Smith, Stuart; Jager, Natalie; Herold-Mende, Christel; Wick, Wolfgang; Pfister, Stefan M.; Vik-Mo, Einar; von Deimling, Andreas; Schlesner, Matthias; Jones, David T. W.; Loose, Matthew; Sill, Martin; Sahm, Felix Share Save
MULTI-OMICS SEQUENCING OF ATYPICAL TERATOID RHABDOID TUMORS UNVEILS A SHARED GROUND-STATE POPULATION PROMOTING SUBGROUP-SPECIFIC DIFFERENTIATION TRAJECTORIES Carmona, Enrique Blanco; Paassen, Irene; He, Jiayou; Buellesbach, Annette; Buhl, Juliane L.; Federico, Aniello; Liu, Ilon; Young, Matthew; Kildisiute, Gerda; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew; Foreman, Nicholas; Hovestadt, Volker; Shaw, McKenzie; Chi, Susan N.; Fruehwald, Michael; Korshunov, Andrey; Hasselblatt, Martin; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella; Drost, Jarno; Kool, Marcel Share Save
ITCC-P4, a preclinical proof-of-concept drug testing platform as a tool for pharmacological screening in pediatric tumor models Indersie, Emilie; Branchereau, Sophie; Fresneau, Brice; Chardot, Christophe; Surdez, Didier; Saint-Charles, Alexandra; da Costa, Maria Eugenia Marques; Carcaboso, Angel M.; Scotlandi, Katia; Moro, Massimo; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Chesler, Louis; Jones, Chris; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Guttke, Christina; Hattersley, Maureen; Colland, Frederic; Strougo, Ashley; Gurgen, Dennis; Hoffmann, Jens; Schueler, Julia; Aviles, Pablo M.; Guillen, Maria Jose; Federico, Aniello; Gopisetty, Apurva; Wierzbinska, Justyna Anna; Schlicker, Andreas; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Huebener, Nicole; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Stancato, Louis F.; Pfister, Stefan M.; Vassal, Gilles; Rief, Eva-Maria; Deas, Olivier Share Save
Molecular analysis of cancer genomes in children with Lynch syndrome: Exploring causal associations Weijers, Dilys D.; Hirsch, Steffen; Bakhuizen, Jette J.; van Engelen, Nienke; Kester, Lennart A.; Kranendonk, Mariette E. G.; Hiemcke-Jiwa, Laura S.; de Vos-Kerkhof, Evelien; Loeffen, Jan L. C.; Autry, Robert J.; Pajtler, Kristian W.; Jaeger, Natalie; Jongmans, Marjolijn C. J.; Kuiper, Roland P. Share Save
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology (vol 29, pg 917, 2023) Sturm, Dominik; Capper, David; Andreiuolo, Felipe; Gessi, Marco; Koelsche, Christian; Reinhardt, Annekathrin; Sievers, Philipp; Wefers, Annika K.; Ebrahimi, Azadeh; Suwala, Abigail K.; Gielen, Gerrit H.; Sill, Martin; Schrimpf, Daniel; Stichel, Damian; Hovestadt, Volker; Daenekas, Bjarne; Rode, Agata; Hamelmann, Stefan; Previti, Christopher; Jaeger, Natalie; Buchhalter, Ivo; Blattner-Johnson, Mirjam; Jones, Barbara C.; Warmuth-Metz, Monika; Bison, Brigitte; Grund, Kerstin; Sutter, Christian; Hirsch, Steffen; Dikow, Nicola; Hasselblatt, Martin; Schueller, Ulrich; Koch, Arend; Gerber, Nicolas U.; White, Christine L.; Buntine, Molly K.; Kinross, Kathryn; Algar, Elizabeth M.; Hansford, Jordan R.; Gottardo, Nicholas G.; Schuhmann, Martin U.; Thomale, Ulrich W.; Driever, Pablo; Gnekow, Astrid; Witt, Olaf; Mueller, Hermann L.; Calaminus, Gabriele; Fleischhack, Gudrun; Kordes, Uwe; Mynarek, Martin; Rutkowski, Stefan; Fruehwald, Michael C.; Kramm, Christof M.; von Deimling, Andreas; Pietsch, Torsten; Sahm, Felix; Pfister, Stefan M.; Jones, David. T. W. Share Save
Mapping pediatric brain tumors to their origins in the developing cerebellum Okonechnikov, Konstantin; Joshi, Piyush; Sepp, Mari; Leiss, Kevin; Sarropoulos, Ioannis; Murat, Florent; Sill, Martin; Beck, Pengbo; Chan, Kenneth Chun-Ho; Korshunov, Andrey; Sah, Felix; Deng, Maximilian Y.; Sturm, Dominik; DeSisto, John; Donson, Andrew M.; Foreman, Nicholas K.; Green, Adam L.; Robinson, Giles; Orr, Brent A.; Gao, Qingsong; Darrow, Emily; Hadley, Jennifer L.; Northcott, Paul A.; Gojo, Johannes; Kawauchi, Daisuke; Hovestadt, Volker; Filbin, Mariella G.; von Deimling, Andreas; Zuckermann, Marc; Pajtler, Kristian W.; Kool, Marcel; Jones, David T. W.; Jaeger, Natalie; Kutscher, Lena M.; Kaessmann, Henrik; Pfister, Stefan M. Share Save
Mitochondrial DNA mutations in Medulloblastoma Funke, Viktoria L. E.; Sandmann, Sarah; Melcher, Viktoria; Seggewiss, Jochen; Horvath, Judit; Jaeger, Natalie; Kool, Marcel; Jones, David T. W.; Pfister, Stefan M. M.; Milde, Till; Rutkowski, Stefan; Mynarek, Martin; Varghese, Julian; Straeter, Ronald; Rust, Stephan; Seelhoefer, Anja; Reunert, Janine; Fiedler, Barbara; Schueller, Ulrich; Marquardt, Thorsten; Kerl, Kornelius Share Save
DELINEATING MEDIATORS OF ONCOGENESIS IN FOXR2-EXPRESSING DIFFUSE MIDLINE GLIOMAS Tsai, Jessica; Cejas, Paloma; Coppola, Marissa; Wang, Dayle; Patel, Smruti; Wu, David; Arounleut, Phonepasong; Wei, Xin; Zhou, Ningxuan; Syamala, Sudeepa; Dubois, Frank; Pelton, Kristine; Vogelzang, Jayne; Sousa, Cecilia; Baguette, Audrey; Chen, Xiaolong; Condurat, Alexandra; Dixon-Clarke, Sarah; Zhou, Kevin; Lu, Sophie; Gonzalez, Elizabeth; Chacon, Madison; Digiacomo, Jeromy; Kumbhani, Rushil; Novikov, Dana; Tsoli, Maria; Ziegler, David; Dirksen, Uta; Jager, Natalie; Balsubramanian, Gnana Prakash; Kramm, Christof; Nathrath, Michaela; Bielack, Stefan; Baker, Suzanne; Zhang, Jinghui; McFarland, James; Getz, Gad; Aguet, Francois; Jabado, Nada; Witt, Olaf; Pfister, Stefan; Ligon, Keith; Hovestadt, Volker; Kleinman, Claudia; Long, Henry; Jones, David; Bandopadhayay, Pratiti; Phoenix, Timothy Share Save
DECIPHERING THE RELATIONSHIP OF MICROSATELLITE-INSTABILITY AND MUTATIONAL BURDEN IN HIGH-GRADE GLIOMA PATIENTS WITH CONSTITUTIONALLY IMPAIRED DNA DAMAGE RESPONSE Blattner-Johnson, Mirjam; Sturm, Dominik; Jones, Barbara C.; Previti, Christopher; Sievers, Philipp; Jaeger, Natalie; Hirsch, Steffen; Dikow, Nicola; Sahm, Felix; Kramm, Christof M.; Witt, Olaf; Pfister, Stefan M.; Jones, David T. W. Share Save
DEVELOPMENT OF A FUNCTIONAL PLATFORM FOR REAL-TIME PERSONALIZED DRUG SENSITIVITY PROFILING OF PATIENT-DERIVED 3D FRESH TUMOR TISSUE CULTURES IN THE PEDIATRIC PRECISION ONCOLOGY PROGRAM INFORM Peterziel, Heike; Jamaladdin, Nora; El Harouni, Dina; Gerloff, Xenia F.; Herter, Sonja; Fiesel, Petra; Berker, Yannick; Blattner-Johnson, Mirjam; Schramm, Kathrin; Jones, Barbara C.; Reuss, David; Turunen, Laura; Friedenauer, Aileen; Holland-Letz, Tim; Sill, Martin; Weiser, Lena; Previti, Christopher; Ubramanian, Gnanaprakash Balas; Gerber, Nicolas U.; Gojo, Johannes; Hutter, Caroline; Ora, Ingrid; Lohi, Olli; Kattamis, Antonis; De Wilde, Bram; Termann, Frank Wes; Tippelt, Stephan; Graf, Norbert; Nathrath, Michaela; Sparber-Sauer, Monika; Sehested, Astrid; Kramm, Christof M.; Dirksen, Uta; Kallioniemi, Olli; Pfister, Stefan M.; Van Tilburg, Cornelis M.; Jones, David T. W.; Saarela, Jani; Pietiainen, Vilja; Jager, Natalie; Schlesner, Matthias; Kopp-Schneider, Annette; Oppermann, Sina; Milde, Till; Witt, Olaf; Oehme, Ina Share Save
CLINICAL RESPONSE TO THE PDGFRA/KIT INHIBITOR AVAPRITINIB IN PEDIATRIC AND YOUNG ADULT HIGH-GRADE GLIOMA PATIENTS WITH H3K27M OR PDGFRA GENOMIC ALTERATIONS Trissal, Maria; Mayr, Lisa; Schwark, Kallen; LaBelle, Jenna; Kong, Seongbae; Furtner, Julia; Weiler-Wichtl, Liesa; Supko, Jeffrey; Rozowsky, Jacob; Hack, Olivia; Groves, Andrew; Marques, Joana; Leiss, Ulrike; Rosenmayr, Verena; Dubois, Frank; Greenwald, Noah F.; Madlener, Sibylle; Guntner, Armin Sebastian; Palova, Hana; Stepien, Natalia; Lotsch-Gojo, Daniela; Dorfer, Christian; Dieckmann, Karen; Peyrl, Andreas; Azizi, Amadeo A.; Baumgartner, Alicia; Slaby, Ondrej; Pokorna, Petra; Bandopadhayay, Pratiti; Beroukhim, Rameen; Ligon, Keith L.; Kramm, Christof M.; Bronsema, Annika; Bailey, Simon; Stucklin, Ana Guerreiro; Mueller, Sabine Mueller; Jones, David T. W.; Jager, Natalie; Mullauer, Leonhard; Haberler, Christine; Kumar-Sinha, Chandan; Chinnaiyan, Arul; Mody, Rajen; Sterba, Jaroslav; Skrypek, Mary; Martinez, Nina; Bowers, Daniel C.; Koschmann, Carl Koschmann; Gojo, Johannes; Filbin, Mariella Share Save
Group-specific cellular metabolism in Medulloblastoma Funke, Viktoria L. E.; Walter, Carolin; Melcher, Viktoria; Wei, Lanying; Sandmann, Sarah; Hotfilder, Marc; Varghese, Julian; Jaeger, Natalie; Kool, Marcel; Jones, David T. W.; Pfister, Stefan M.; Milde, Till; Mynarek, Martin; Rutkowski, Stefan; Seggewiss, Jochen; Jeising, Daniela; de Faria, Flavia W.; Marquardt, Thorsten; Albert, Thomas K.; Schueller, Ulrich; Kerl, Kornelius Share Save
The potential of PARP as a therapeutic target across pediatric solid malignancies Keller, Kaylee M.; Koetsier, Joost; Schild, Linda; Amo-Addae, Vicky; Eising, Selma; van den Handel, Kim; Ober, Kimberley; Koopmans, Bianca; Essing, Anke; van den Boogaard, Marlinde L.; Langenberg, Karin P. S.; Jager, Natalie; Kool, Marcel; Pfister, Stefan; Dolman, M. Emmy M.; Molenaar, Jan J.; van Hooff, Sander R. Share Save
Dissecting mechanisms underlying FOXR2-mediated gliomagenesis in diffuse midline gliomas Tsai, Jessica W.; Cejas, Paloma; Coppola, Marissa; Wang, Dayle K.; Patel, Smruti; Wu, David W.; Arounleut, Phonepasong; Wei, Xin; Zhou, Ningxuan; Syamala, Sudeepa; Dubois, Frank P.; Pelton, Kristine; Vogelzang, Jayne; Sousa, Cecilia; Baguette, Audrey; Chen, Xiaolong; Condurat, Alexandra L.; Dixon-Clarke, Sarah E.; Charles, Annarah; Zhou, Kevin N.; Lu, Sophie D.; Gonzalez, Elizabeth M.; Chacon, Madison S.; Digiacomo, Jeromy J.; Kumbhani, Rushil; Novikov, Dana; Tsoli, Maria; Ziegler, David S.; Dirksen, Uta; Jager, Natalie; Balasubramanian, Gnana Prakash; Kramm, Christof M.; Nathrath, Michaela; Bielack, Stefan; Baker, Suzanne J.; Zhang, Jinghui; McFarland, James M.; Getz, Gad; Aguet, Francois; Jabado, Nada; Witt, Olaf; Pfister, Stefan M.; Ligon, Keith L.; Hovestadt, Volker; Kleinman, Claudia; Long, Henry; Jones, David T.; Bandopadhayay, Pratiti; Phoenix, Timothy N. Share Save
Clinical response to the PDGFRα inhibitor avapritinib in high-grade glioma patients Mayr, Lisa; Trissal, Maria; Schwark, Kallen; Labelle, Jenna; Groves, Andrew; Furtner-Srajer, Julia; Supko, Jeffrey; Weiler-Wichtl, Liesa; Hack, Olivia; Rozowsky, Jacob; Marques, Joana G.; Pandatharatna, Eshini; Leiss, Ulrike; Rosenmayr, Verena; Dubois, Frank; Greenwald, Noah F.; Madlener, Sibylle; Guntner, Armin S.; Palova, Hana; Stepien, Natalia; Lotsch-Gojo, Daniela; Dorfer, Christian; Dieckmann, Karin; Peyrl, Andreas; Azizi, Amedeo A.; Baumgartner, Alicia; Slaby, Ondrej; Pokorna, Petra; Bandopadhayay, Pratiti; Beroukhim, Rameen; Ligon, Keith; Kramm, Christof; Bronsema, Annika; Bailey, Simon; Stucklin, Ana Guerreiro; Mueller, Sabine; Jones, David T.; Jager, Natalie; Sterba, Jaroslav; Mullauer, Leonhard; Haberler, Christine; Kumar-Sinha, Chandan; Chinnaiyan, Arul; Mody, Rajen; Skrypek, Mary; Martinez, Nina; Bowers, Daniel C.; Koschmann, Carl; Gojo, Johannes; Filbin, Mariella Share Save
Reply to Li and Colleagues Kratz, Christian P.; Smirnov, Dmitrii; Autry, Robert; Jaeger, Natalie; Waszak, Sebastian M.; Grosshennig, Anika; Berutti, Riccardo; Wendorff, Mareike; Hainaut, Pierre; Pfister, Stefan M.; Prokisch, Holger; Ripperger, Tim; Malkin, David Share Save
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