Not logged in Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer Cortesi, Alice; Gandolfi, Francesco; Arco, Fabiana; Di Chiaro, Pierluigi; Valli, Emanuele; Polletti, Sara; Noberini, Roberta; Gualdrini, Francesco; Attanasio, Sergio; Citron, Francesca; Ho, I-lin; Shah, Rutvi; Yen, Er-Yen; Spinella, Mara Cetty; Ronzoni, Simona; Rodighiero, Simona; Mitro, Nico; Bonaldi, Tiziana; Ghisletti, Serena; Monticelli, Silvia; Viale, Andrea; Diaferia, Giuseppe Riccardo; Natoli, Gioacchino Share Save
Blockade of CD24 sensitizes pancreatic cancer to Kras inhibitors Wei, Yongkun; Liu, Minghui; Yen, Er-Yen; Yao, Jun; Nguyen, Phuoc T.; Wang, Xiaofei; Yang, Zecheng; Yousef, Abdelrahman; Pan, Dean; Jin, Yanqing; Theady, Madelaine S.; Park, Jangho; Cai, Yiming; Takeda, Mitsunobu; Vasquez, Matthew; Zhou, Yong; Zhao, Hong; Viale, Andrea; Wang, Huamin; Zhao, Dan; DePinho, Ronald A.; Yao, Wantong; Ying, Haoqiang Share Save
ASCL2+tumor cells modulate the response of colorectal cancer to MAPK targeting therapy Villarreal, Oscar E.; Lee, Hey Min; Ha Tran; Machado, Annette; Alshenaifi, Jumanah; Wong, Chi Wut; Coker, Olu; Minelli, Rosalba; Peoples, Michael; Martinez, Alejandro Hernandez; Fowlkes, Natalie; Kanikarla, Preeti; Lin, Kangyu; Bristow, Christopher; Viale, Andrea; Marszalek, Joseph R.; Shen, John Paul; Kopetz, Scott Share Save
Hyperprogression due to myeloid mimicry in renal medullary carcinoma treated with nivolumab plus ipilimumab Soeung, Melinda; Yan, Xinmiao; Zhang, Li; Perelli, Luigi; Chen, Jianfeng; Tidwell, Becky Slack; Khan, Hania; Le, Courtney N.; Lam, Truong N.; Bhattacharya, Nirjar; Shah, Rutvi; Ho, I-Lin; Chen, Ziheng; Lundgren, Sebastian R.; Feng, Ningping; Zanca, Ciro; Karki, Menuka; Millward, Niki Marie Zacharias; He, Rong; Sheth, Rahul A.; Tharakeswara, Bathala K.; Rao, Priya; Daw, Najat C.; Tripathi, Durga N.; Walker, Cheryl L.; Han, Guangchun; Chu, Yanshuo; Wang, Ruiping; Dang, Minghao; Dai, Enyu; Peng, Fuduan; Liu, Yunhe; Jadhav, Akshaya S.; Lang, Wenhua; Arrechedera, Claudio A.; Clemente, Leticia Campos; Parra-Cuentas, Edwin R.; Lu, Hsinyi; Haymaker, Cara; Wistuba, Ignacio I.; Futreal, Andrew; Heffernan, Timothy; Viale, Andrea; Draetta, Giulio F.; Tannir, Nizar M.; Gao, Jianjun; Wang, Linghua; Genovese, Giannicola; Msaouel, Pavlos Share Save
Clonal dominance defines metastatic dissemination in pancreatic cancer Ho, I-Lin; Li, Chieh-Yuan; Wang, Fuchenchu; Zhao, Li; Liu, Jingjing; Yen, Er-Yen; Dyke, Charles A.; Shah, Rutvi; Liu, Zhaoliang; Cetin, Ali Osman; Chu, Yanshuo; Citron, Francesca; Attanasio, Sergio; Corti, Denise; Darbaniyan, Faezeh; Del Poggetto, Edoardo; Loponte, Sara; Liu, Jintan; Soeung, Melinda; Chen, Ziheng; Jiang, Shan; Jiang, Hong; Inoue, Akira; Gao, Sisi; Deem, Angela; Feng, Ningping; Ying, Haoqiang; Kim, Michael; Giuliani, Virginia; Genovese, Giannicola; Zhang, Jianhua; Futreal, Andrew; Maitra, Anirban; Heffernan, Timothy; Wang, Linghua; Do, Kim-Anh; Gargiulo, Gaetano; Draetta, Giulio; Carugo, Alessandro; Lin, Ruitao; Viale, Andrea Share Save
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma Thongon, Natthakan; Ma, Feiyang; Baran, Natalia; Lockyer, Pamela; Liu, Jintan; Jackson, Christopher; Rose, Ashley; Furudate, Ken; Wildeman, Bethany; Marchesini, Matteo; Marchica, Valentina; Storti, Paola; Todaro, Giannalisa; Ganan-Gomez, Irene; Adema, Vera; Rodriguez-Sevilla, Juan Jose; Qing, Yun; Ha, Min Jin; Fonseca, Rodrigo; Stein, Caleb; Class, Caleb; Tan, Lin; Attanasio, Sergio; Garcia-Manero, Guillermo; Giuliani, Nicola; Berrios Nolasco, David; Santoni, Andrea; Cerchione, Claudio; Bueso-Ramos, Carlos; Konopleva, Marina; Lorenzi, Philip; Takahashi, Koichi; Manasanch, Elisabet; Sammarelli, Gabriella; Kanagal-Shamanna, Rashmi; Viale, Andrea; Chesi, Marta; Colla, Simona Share Save
Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer Perelli, Luigi; Carbone, Federica; Zhang, Li; Huang, Justin K. K.; Le, Courtney; Khan, Hania; Citron, Francesca; Del Poggetto, Edoardo; Gutschner, Tony; Tomihara, Hideo; Soeung, Melinda; Minelli, Rosalba; Srinivasan, Sanjana; Peoples, Michael; Lam, Truong Nguyen Anh; Lundgren, Sebastian; Xia, Ruohan; Zhu, Cihui; Mohamed, Alaa M. T.; Zhang, Jianhua; Sircar, Kanishka; Sgambato, Alessandro; Gao, JianJun; Jonasch, Eric; Draetta, Giulio F.; Futreal, Andrew; Bakouny, Ziad; Van Allen, Eliezer M.; Choueiri, Toni; Signoretti, Sabina; Msaouel, Pavlos; Litchfield, Kevin; Turajlic, Samra; Wang, Linghua; Chen, Ying Bei; Di Natale, Renzo G.; Hakimi, A. Ari; Giuliani, Virginia; Heffernan, Timothy P.; Viale, Andrea; Bristow, Christopher A.; Tannir, Nizar M.; Carugo, Alessandro; Genovese, Giannicola Share Save
SMARCB1 regulates the hypoxic stress response in sickle cell trait Soeung, Melinda; Perelli, Luigi; Chen, Ziheng; Dondossola, Eleonora; Ho, -Lin; Carbone, Federica; Zhang, Li; Khan, Hania; Le, Courtney N.; Zhu, Cihui; Peoples, Michael D.; Feng, Ningping; Jiang, Shan; Zacharias, Niki Millward; Minelli, Rosalba; Shapiro, Daniel D.; Deem, Angela K.; Gao, Sisi; Cheng, Emily H.; Lucchetti, Donatella; Walker, Cheryl L.; Carugo, Alessandro; Giuliani, Virginia; Heffernan, Timothy P.; Viale, Andrea; Tannir, Nizar M.; Draetta, Giulio F.; Msoue, Pavlo; Genovese, Giannicola Share Save
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells Halbrook, Christopher J.; Thurston, Galloway; Boyer, Seth; Anaraki, Cecily; Jimenez, Jennifer A.; McCarthy, Amy; Steele, Nina G.; Kerk, Samuel A.; Hong, Hanna S.; Lin, Lin; Law, Fiona V.; Felton, Catherine; Scipioni, Lorenzo; Sajjakulnukit, Peter; Andren, Anthony; Beutel, Alica K.; Singh, Rima; Nelson, Barbara S.; van den Bergh, Fran; Krall, Abigail S.; Mullen, Peter J.; Zhang, Li; Batra, Sandeep; Morton, Jennifer P.; Stanger, Ben Z.; Christofk, Heather R.; Digman, Michelle A.; Beard, Daniel A.; Viale, Andrea; Zhang, Ji; Crawford, Howard C.; Pasca di Magliano, Marina; Jorgensen, Claus; Lyssiotis, Costas A. Share Save
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression Cao, Shaolong; Wang, Jennifer R.; Ji, Shuangxi; Yang, Peng; Dai, Yaoyi; Guo, Shuai; Montierth, Matthew D.; Shen, John Paul; Zhao, Xiao; Chen, Jingxiao; Lee, Jaewon James; Guerrero, Paola A.; Spetsieris, Nicholas; Engedal, Nikolai; Taavitsainen, Sinja; Yu, Kaixian; Livingstone, Julie; Bhandari, Vinayak; Hubert, Shawna M.; Daw, Najat C.; Futreal, P. Andrew; Efstathiou, Eleni; Lim, Bora; Viale, Andrea; Zhang, Jianjun; Nykter, Matti; Czerniak, Bogdan A.; Brown, Powel H.; Swanton, Charles; Msaouel, Pavlos; Maitra, Anirban; Kopetz, Scott; Campbell, Peter; Speed, Terence P.; Boutros, Paul C.; Zhu, Hongtu; Urbanucci, Alfonso; Demeulemeester, Jonas; Van Loo, Peter; Wang, Wenyi Share Save
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma Giuliani, Virginia; Miller, Meredith A.; Liu, Chiu-Yi; Hartono, Stella R.; Class, Caleb A.; Bristow, Christopher A.; Suzuki, Erika; Sanz, Lionel A.; Gao, Guang; Gay, Jason P.; Feng, Ningping; Rose, Johnathon L.; Tomihara, Hideo; Daniele, Joseph R.; Peoples, Michael D.; Bardenhagen, Jennifer P.; Geck Do, Mary K.; Chang, Qing E.; Vangamudi, Bhavatarini; Vellano, Christopher; Ying, Haoqiang; Deem, Angela K.; Do, Kim-Anh; Genovese, Giannicola; Marszalek, Joseph R.; Kovacs, Jeffrey J.; Kim, Michael; Fleming, Jason B.; Guccione, Ernesto; Viale, Andrea; Maitra, Anirban; Emilia Di Francesco, M.; Yap, Timothy A.; Jones, Philip; Draetta, Giulio; Carugo, Alessandro; Chedin, Frederic; Heffernan, Timothy P. Share Save
Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer Inoue, Akira; Robinson, Frederick S.; Minelli, Rosalba; Tomihara, Hideo; Rizi, Bahar Salimian; Rose, Johnathon L.; Kodama, Takahiro; Srinivasan, Sanjana; Harris, Angela L.; Zuniga, Andy M.; Mullinax, Robert A.; Ma, Xiaoyan; Seth, Sahil; Daniele, Joseph R.; Peoples, Michael D.; Loponte, Sara; Akdemir, Kadir C.; Khor, Tin Oo; Feng, Ningping; Roszik, Jason; Sobieski, Mary M.; Brunell, David; Stephan, Clifford; Giuliani, Virginia; Deem, Angela K.; Shingu, Takashi; Deribe, Yonathan Lissanu; Menter, David G.; Heffernan, Timothy P.; Viale, Andrea; Bristow, Christopher A.; Kopetz, Scott; Draetta, Giulio F.; Genovese, Giannicola; Carugo, Alessandro Share Save
miR-9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC Citron, Francesca; Segatto, Ilenia; Musco, Lorena; Pellarin, Ilenia; Rampioni Vinciguerra, Gian Luca; Franchin, Giovanni; Fanetti, Giuseppe; Micciche, Francesco; Giacomarra, Vittorio; Lupato, Valentina; Favero, Andrea; Concina, Isabella; Srinivasan, Sanjana; Avanzo, Michele; Castiglioni, Isabella; Barzan, Luigi; Sulfaro, Sandro; Petrone, Gianluigi; Viale, Andrea; Draetta, Giulio F.; Vecchione, Andrea; Belletti, Barbara; Baldassarre, Gustavo Share Save
Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma Puca, Francesca; Yu, Fei; Bartolacci, Caterina; Pettazzoni, Piergiorgio; Carugo, Alessandro; Huang-Hobbs, Emmet; Liu, Jintan; Zanca, Ciro; Carbone, Federica; Del Poggetto, Edoardo; Gumin, Joy; Dasgupta, Pushan; Seth, Sahil; Srinivasan, Sanjana; Lang, Frederick F.; Sulman, Erik P.; Lorenzi, Philip L.; Tan, Lin; Shan, Mengrou; Tolstyka, Zachary P.; Kachman, Maureen; Zhang, Li; Gao, Sisi; Deem, Angela K.; Genovese, Giannicola; Scaglioni, Pier Paolo; Lyssiotis, Costas A.; Viale, Andrea; Draetta, Giulio F. Share Save
Loss of ARID1A Promotes Epithelial-Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress Tomihara, Hideo; Carbone, Federica; Perelli, Luigi; Huang, Justin K.; Soeung, Melinda; Rose, Johnathon L.; Robinson, Frederick S.; Deribe, Yonathan Lissanu; Feng, Ningping; Takeda, Mitsunobu; Inoue, Akira; Del Poggetto, Edoardo; Deem, Angela K.; Maitra, Anirban; Msaouel, Pavlos; Tannir, Nizar M.; Draetta, Giulio F.; Viale, Andrea; Heffernan, Timothy P.; Bristow, Christopher A.; Carugo, Alessandro; Genovese, Giannicola Share Save
Dissection of clonal heterogeneity unmasks pre-existing chemoresistance and new metabolic vulnerabilities in pancreatic cancer Seth, Sahil; Li, Chieh-Yuan; Loponte, Sara; Ho, I-Lin; Corti, Denise; Sapio, Luigi; Del Poggetto, Edoardo; Peoples, Michael; Karpinets, Tatiana; Robinson, Frederick S.; Jiang, Shan; Dutta, Prasanta; Marszalek, Joseph; Di Francesco, Maria E.; Heffernan, Timothy P.; Giuliani, Virginia; Bhattacharya, Pratip K.; Genovese, Giannicola; Futreal, Andrew; Draetta, Giulio; Viale, Andrea; Carugo, Alessandro Share Save
Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors Seth, Sahil; Li, Chieh-Yuan; Ho, I-Lin; Corti, Denise; Loponte, Sara; Sapio, Luigi; Del Poggetto, Edoardo; Yen, Er-Yen; Robinson, Frederick Scott; Peoples, Michael; Karpinets, Tatiana; Deem, Angela Kay; Kumar, Tapsi; Song, Xingzhi; Jiang, Shan; Kang, Ya'an; Fleming, Jason; Kim, Michael; Zhang, Jianhua; Maitra, Anirban; Heffernan, Timothy Paul; Giuliani, Virginia; Genovese, Giannicola; Futreal, Andrew; Draetta, Giulio Francesco; Carugo, Alessandro; Viale, Andrea Share Save
Perturbation of proteostasis is lethal in SMARCB1-deficient tumors Soeung, Melinda; Carugo, Alessandro; Robinson, Frederick Scott; Minelli, Rosalba; Carbone, Federica; Maitra, Anirban; Viale, Andrea; Roberts, Charles W. M.; Tannir, Nizar; Draetta, Giulio F.; Genovese, Giannicola Share Save
Clonal dissection of pancreatic tumors unmasks functional and genomic heterogeneous long-term self-renewing compartments at the origin of treatment resistance Seth, Sahil; Li, Chieh-Yuan; Ho, I-Lin; Corti, Denise; Loponte, Sara; Sapio, Luigi; Del Poggetto, Edoardo; Peoples, Michael; Karpinets, Tatiana; Genovese, Giannicola; Futreal, Andrew; Draetta, Giulio; Carugo, Alessandro; Viale, Andrea Share Save
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