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R

Roberto Pacifici

Department of Medicine

64H-index
198Paper Count
1.5WCitation Count
Published Papers 76
Publication Date
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Bacterial specificity of the gut microbiome predicts bone density in primary hyperparathyroidism
errBone Research
IF15
err2026-05-25
err0
errOAAI
errHamid Y. Dar; Jiali Fang; Sanchiti Patil; Nand K. Roy; Sanchita Agarwal; M. Neale Weitzmann; Rheinallt M. Jones; John P. Bilezikian; Roberto Pacifici
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Gender-affirming hormone therapy preserves skeletal maturation in young mice via the gut microbiome
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-03-26
err0
errOAAI
errPal, Subhashis; Morgan, Xochitl; Dar, Hamid Y.; Gacasan, Camilo Anthony; Patil, Sanchiti; Stoica, Andreea; Hu, Yi-Juan; Weitzmann, M. Neale; Jones, Rheinallt M.; Pacifici, Roberto
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A two-cohort study on the association between the gut microbiota and bone density, microarchitecture, and strength
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2023-09-21
err9
errOAAI
errOkoro, Paul C.; Orwoll, Eric S.; Huttenhower, Curtis; Morgan, Xochitl; Kuntz, Thomas M.; Mciver, Lauren J.; Dufour, Alyssa B.; Bouxsein, Mary L.; Langsetmo, Lisa; Farsijani, Samaneh; Kado, Deborah M.; Pacifici, Roberto; Sahni, Shivani; Kiel, Douglas P.
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errSave
Inflammation and gut dysbiosis as drivers of CKD-MBD
errNATURE REVIEWS NEPHROLOGY
IF39.8
err2023-07-24
err15
PREAI
errEvenepoel, Pieter; Stenvinkel, Peter; Shanahan, Catherine; Pacifici, Roberto
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errSave
Dietary phosphorus consumption alters T cell populations, cytokine production, and bone volume in mice
errJCI INSIGHT
IF6.1
err2023-05-22
err3
errOAAI
errRoberts, Joseph L.; Yu, Mingcan; Viggeswarapu, Manjula; Arnst, Jamie L.; Pacifici, Roberto; Beck Jr, George R.
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errSave
Callus γδT cells and microbe-induced intestinal Th17 cells improve fracture healing in mice
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-04-17
err15
errOAAI
errDar, Hamid Y.; Perrien, Daniel S.; Pal, Subhashis; Stoica, Andreea; Uppuganti, Sasidhar; Nyman, Jeffry S.; Jones, Rheinallt M.; Weitzmann, M. Neale; Pacifici, Roberto
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errSave
A TrkB agonist prodrug prevents bone loss via inhibiting asparagine endopeptidase and increasing osteoprotegerin
errNATURE COMMUNICATIONS
IF15.7
err2022-08-16
err18
errOAAI
errXiong, Jing; Liao, Jianming; Liu, Xia; Zhang, Zhaohui; Adams, Jonathan; Pacifici, Roberto; Ye, Keqiang
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The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-06-15
err23
errOAAI
errPal, Subhashis; Perrien, Daniel S.; Yumoto, Tetsuya; Faccio, Roberta; Stoica, Andreea; Adams, Jonathan; Coopersmith, Craig M.; Jones, Rheinallt M.; Weitzmann, M. Neale; Pacifici, Roberto
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errSave
Cyclic Adenosine Monophosphate (cAMP)-Dependent Phosphodiesterase Inhibition Promotes Bone Anabolism Through CD8+ T Cell Wnt-10b Production in Mice
errJBMR PLUS
IF2.4
err2022-05-31
err7
errOAAI
errRoser-Page, Susanne; Weiss, Daiana; Vikulina, Tatyana; Yu, Mingcan; Pacifici, Roberto; Weitzmann, M. Neale
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errSave
Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2021-02-15
err78
errOAAI
errYu, Mingcan; Pal, Subhashis; Paterson, Cameron W.; Li, Jau-Yi; Tyagi, Abdul Malik; Adams, Jonathan; Coopersmith, Craig M.; Weitzmann, M. Neale; Pacifici, Roberto
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errSave
Plasma high-resolution metabolomics identifies linoleic acid and linked metabolic pathways associated with bone mineral density
errCLINICAL NUTRITION
IF7.4
err2021-02-01
err23
errOAAI
errBellissimo, Moriah P.; Ziegler, Thomas R.; Jones, Dean P.; Liu, Ken H.; Fernandes, Jolyn; Roberts, Joseph L.; Weitzmann, M. Neale; Pacifici, Roberto; Alvarez, Jessica A.
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errSave
The gut microbiota is a transmissible determinant of skeletal maturation
errELIFE
IF0
err2021-01-12
err33
errOAAI
errTyagi, Abdul Malik; Darby, Trevor M.; Hsu, Emory; Yu, Mingcan; Pal, Subhashis; Dar, Hamid; Li, Jau-Yi; Adams, Jonathan; Jones, Rheinallt M.; Pacifici, Roberto
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errSave
Role of Gut Microbiota in the Skeletal Response to PTH
errJOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
err2020-12-01
err24
errOAAI
errPacifici, Roberto
errShare
errSave
Metabolomic Associations with Serum Bone Turnover Markers
errNUTRIENTS
IF5
err2020-10-16
err23
errOAAI
errBellissimo, Moriah P.; Roberts, Joseph L.; Jones, Dean P.; Liu, Ken H.; Taibl, Kaitlin R.; Uppal, Karan; Weitzmann, M. Neale; Pacifici, Roberto; Drissi, Hicham; Ziegler, Thomas R.; Alvarez, Jessica A.
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errSave
PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells
errNATURE COMMUNICATIONS
IF15.7
err2020-01-24
err109
errOAAI
errYu, Mingcan; Tyagi, Abdul Malik; Li, Jau-Yi; Adams, Jonathan; Denning, Timothy L.; Weitzmann, M. Neale; Jones, Rheinallt M.; Pacifici, Roberto
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errSave
The gut-bone axis: how bacterial metabolites bridge the distance
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2019-07-15
err245
errOAAI
errZaiss, Mario M.; Jones, Rheinallt M.; Schett, Georg; Pacifici, Roberto
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errSave
The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression
errIMMUNITY
IF26.3
err2018-12-01
err366
errOAAI
errTyagi, Abdul Malik; Yu, Mingcan; Darby, Trevor M.; Vaccaro, Chiara; Li, Jau-Yi; Owens, Joshua A.; Hsu, Emory; Adams, Jonathan; Weitzmann, M. Neale; Jones, Rheinallt M.; Pacifici, Roberto
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IL-17 Receptor Signaling in Osteoblasts/Osteocytes Mediates PTH-Induced Bone Loss and Enhances Osteocytic RANKL Production
errJOURNAL OF BONE AND MINERAL RESEARCH
IF5.9
err2018-11-06
err63
errOAAI
errLi, Jau-Yi; Yu, Mingcan; Tyagi, Abdul Malik; Vaccaro, Chiara; Hsu, Emory; Adams, Jonathan; Bellido, Teresita; Weitzmann, M. Neale; Pacifici, Roberto
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errSave
Osteomicrobiology: The influence of gut microbiota on bone in health and disease
errBONE
IF3.6
err2018-10-01
err64
PREAI
errJones, Rheinallt M.; Mulle, Jennifer G.; Pacifici, Roberto
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errSave
CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin
errANNALS OF THE NEW YORK ACADEMY OF SCIENCES
IF4.8
err2018-03-03
err12
errOAAI
errRoser-Page, Susanne; Vikulina, Tatyana; Weiss, Daiana; Habib, Mark M.; Beck, George R., Jr.; Pacifici, Roberto; Lane, Timothy F.; Weitzmann, M. Neale
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Richard A. Flavell
H-index: 246 · Papers: 1.5K
G
Georg Schett
H-index: 154 · Papers: 1.7K
H
Harry K. Genant
H-index: 146 · Papers: 871
C
Curtis Huttenhower
H-index: 142 · Papers: 636
D
Douglas P. Kiel
H-index: 132 · Papers: 778
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