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SaveA Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice
Bodas, Cristina; Felipe, Irene; Chanez, Brice; Lafarga, Miguel; Lopez de Maturana, Evangelina; Martinez de Villarreal, Jaime; del Pozo, Natalia; Malumbres, Marina; Vargiu, Pierfrancesco; Cayuela, Ana; Peset, Isabel; Connelly, Katelyn; Hoskins, Jason; Mendez, Raul; Amundadottir, Laufey; Malats, Nuria; Ortega, Sagrario; Real, Francisco X. Share Save T Cell-Specific Inactivation of the PI3K p110α Catalytic Subunit: Effect in T Cell Differentiation and Antigen-Specific ResponsesBriones, Alejandro C.; del Estal, Laura; Villa-Gomez, Cristina; Bermejo, Veronica; Cervera, Isabel; Gutierrez-Huerta, Pedro; Montes-Casado, Maria; Ortega, Sagrario; Barbacid, Mariano; Rojo, Jose Maria; Portoles, Pilar Share Save PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosisSanz-Flores, Maria; Ruiz-Torres, Miguel; Aguirre-Portoles, Cristina; El Bakkali, Aicha; Salvador-Barbero, Beatriz; Villarroya-Beltri, Carolina; Ortega, Sagrario; Megias, Diego; Gerlich, Daniel W.; Alvarez-Fernandez, Monica; Malumbres, Marcos Share Save CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation (vol 68, pg 336, 2017)Lopez-Mejia, Isabel C.; Lagarrigue, Sylviane; Giralt, Albert; Martinez-Carreres, Laia; Martin, Javier; Ortega, Sagrario; Zanou, Nadege; Denechaud, Pierre-Damien; Castillo-Armengol, Judit; Chavey, Carine; Orpinell, Meritxell; Delacuisine, Brigitte; Nasrallah, Anita; Collodet, Caterina; Zhang, Lianjun; Viollet, Benoit; Hardie, D. Grahame; Fajas, Lluis Share Save Share Save Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotypeMaus, Mate; Lopez-Polo, Vanessa; Mateo, Lidia; Lafarga, Miguel; Aguilera, Monica; De Lama, Eugenia; Meyer, Kathleen; Sola, Anna; Lopez-Martinez, Cecilia; Lopez-Alonso, Ines; Guasch-Piqueras, Marc; Hernandez-Gonzalez, Fernanda; Chaib, Selim; Rovira, Miguel; Sanchez, Mayka; Faner, Rosa; Agusti, Alvar; Dieguez-Hurtado, Rodrigo; Ortega, Sagrario; Manonelles, Anna; Engelhardt, Stefan; Monteiro, Freddy; Attolini, Camille Stephan-Otto; Prats, Neus; Albaiceta, Guillermo; Cruzado, Josep M.; Serrano, Manuel Share Save Decoding protein methylation function with thermal stability analysisSayago, Cristina; Sanchez-Wandelmer, Jana; Garcia, Fernando; Hurtado, Begona; Lafarga, Vanesa; Prieto, Patricia; Zarzuela, Eduardo; Ximenez-Embun, Pilar; Ortega, Sagrario; Megias, Diego; Fernandez-Capetillo, Oscar; Malumbres, Marcos; Munoz, Javier Share Save Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injuryTan, Can; Norden, Pieter R.; Yu, Wei; Liu, Ting; Ujiie, Naoto; Lee, Sun Kyong; Yan, Xiaocai; Dyakiv, Yaryna; Aoto, Kazushi; Ortega, Sagrario; De Plaen, Isabelle G.; Sampath, Venkatesh; Kume, Tsutomu Share Save Kras oncogene ablation prevents resistance in advanced lung adenocarcinomasSalmon, Marina; Alvarez-Diaz, Ruth; Fustero-Torre, Coral; Brehey, Oksana; Lechuga, Carmen G.; Sanclemente, Manuel; Fernandez-Garcia, Fernando; Lopez-Garcia, Alejandra; Martin-Guijarro, Maria Carmen; Rodriguez-Perales, Sandra; Bousquet-Mur, Emily; Morales-Cacho, Lucia; Mulero, Francisca; Al-Shahrour, Fatima; Martinez, Lola; Dominguez, Orlando; Caleiras, Eduardo; Ortega, Sagrario; Guerra, Carmen; Musteanu, Monica; Drosten, Matthias; Barbacid, Mariano Share Save Share Save Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated regionFernandez, Lara P.; Deleyto-Seldas, Nerea; Colmenarejo, Gonzalo; Sanz, Alba; Wagner, Sonia; Belen Plata-Gomez, Ana; Gomez-Patino, Monica; Molina, Susana; Espinosa-Salinas, Isabel; Aguilar-Aguilar, Elena; Ortega, Sagrario; Grana-Castro, Osvaldo; Loria-Kohen, Viviana; Fernandez-Marcos, Pablo J.; Efeyan, Alejo; Ramirez de Molina, Ana Share Save The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1ABeucher, Anthony; Miguel-Escalada, Irene; Balboa, Diego; De Vas, Matias G.; Angel Maestro, Miguel; Garcia-Hurtado, Javier; Bernal, Aina; Gonzalez-Franco, Roser; Vargiu, Pierfrancesco; Heyn, Holger; Ravassard, Philippe; Ortega, Sagrario; Ferrer, Jorge Share Save Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanismGarcia-Silva, Susana; Benito-Martin, Alberto; Nogues, Laura; Hernandez-Barranco, Alberto; Mazariegos, Marina S.; Santos, Vanesa; Hergueta-Redondo, Marta; Ximenez-Embun, Pilar; Kataru, Raghu P.; Lopez, Ana Amor; Merino, Cristina; Sanchez-Redondo, Sara; Grana-Castro, Osvaldo; Matei, Irina; Nicolas-Avila, Jose Angel; Torres-Ruiz, Raul; Rodriguez-Perales, Sandra; Martinez, Lola; Perez-Martinez, Manuel; Mata, Gadea; Kalinowska, Iwona; Saltari, Annalisa; Martinez-Gomez, Julia M.; Hogan, Sabrina A.; Saragovi, H. Uri; Ortega, Sagrario; Garcia-Martin, Carmen; Boskovic, Jasminka; Levesque, Mitchell P.; Rutkowski, Piotr; Hidalgo, Andres; Munoz, Javier; Megias, Diego; Mehrara, Babak J.; Lyden, David; Peinado, Hector Share Save Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimicsOlmeda, David; Cerezo-Wallis, Daniela; Mucientes, Cynthia; Calvo, Tonantzin G.; Canon, Estela; Alonso-Curbelo, Direna; Ibarz, Nuria; Munoz, Javier; Rodriguez-Peralto, Jose L.; Ortiz-Romero, Pablo; Ortega, Sagrario; Soengas, Maria S. Share Save Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopiasGonzalez-Martinez, Jose; Cwetsch, Andrzej W.; Martinez-Alonso, Diego; Lopez-Sainz, Luis R.; Almagro, Jorge; Melati, Anna; Gomez, Jesus; Perez-Martinez, Manuel; Megias, Diego; Boskovic, Jasminka; Gilabert-Juan, Javier; Grana-Castro, Osvaldo; Pierani, Alessandra; Behrens, Axel; Ortega, Sagrario; Malumbres, Marcos Share Save Share Save KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoformSalmon, Marina; Paniagua, Guillem; Lechuga, Carmen G.; Fernandez-Garcia, Fernando; Zarzuela, Eduardo; Alvarez-Diaz, Ruth; Musteanu, Monica; Guerra, Carmen; Caleiras, Eduardo; Munoz, Javier; Ortega, Sagrario; Drosten, Matthias; Barbacid, Mariano Share Save Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasisMiguel, Veronica; Tituana, Jessica; Ignacio Herrero, J.; Herrero, Laura; Serra, Dolors; Cuevas, Paula; Barbas, Coral; Rodriguez Puyol, Diego; Marquez-Exposito, Laura; Ruiz-Ortega, Marta; Castillo, Carolina; Sheng, Xin; Susztak, Katalin; Ruiz-Canela, Miguel; Salas-Salvado, Jordi; Martinez Gonzalez, Miguel A.; Ortega, Sagrario; Ramos, Ricardo; Lamas, Santiago Share Save Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinasesLynch, Cian J.; Bernad, Raquel; Martinez-Val, Ana; Shahbazi, Marta N.; Nobrega-Pereira, Sandrina; Calvo, Isabel; Blanco-Aparicio, Carmen; Tarantino, Carolina; Garreta, Elena; Richart-Gines, Laia; Alcazar, Noelia; Grana-Castro, Osvaldo; Gomez-Lopez, Gonzalo; Aksoy, Irene; Munoz-Martin, Maribel; Martinez, Sonia; Ortega, Sagrario; Prieto, Susana; Simboeck, Elisabeth; Camasses, Alain; Stephan-Otto Attolini, Camille; Fernandez, Agustin F.; Sierra, Marta I.; Fraga, Mario F.; Pastor, Joaquin; Fisher, Daniel; Montserrat, Nuria; Savatier, Pierre; Munoz, Javier; Zernicka-Goetz, Magdalena; Serrano, Manuel Share Save 
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