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Alfred L. Goldberg

university at buffalo, suny

153H-index
488Paper Count
8.6WCitation Count
Published Papers 167
Publication Date
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PSMC5 insufficiency and P320R mutation impair proteasome function
errHUMAN MOLECULAR GENETICS
IF3.2
err2024-05-22
err1
errOAAI
errYu, Zhong-Qiu; Carmichael, Jenny; Collins, Galen A.; D'Agostino, Maria Daniela; Lessard, Mathieu; Firth, Helen, V; Harijan, Pooja; Fry, Andrew E.; Dean, John; Zhang, Jiuchun; Kini, Usha; Goldberg, Alfred L.; Rubinsztein, David C.
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Maximum entropy determination of mammalian proteome dynamics
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-23
err0
errOAAI
errDear, Alexander J.; Garcia, Gonzalo A.; Meisl, Georg; Collins, Galen A.; Knowles, Tuomas P. J.; Goldberg, Alfred L.
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errSave
Molecular mechanism for activation of the 26S proteasome by ZFAND5
errMOLECULAR CELL
IF16.6
err2023-08-01
err0
errOAAI
errLee, Donghoon; Zhu, Yanan; Colson, Louis; Wang, Xiaorong; Chen, Siyi; Tkacik, Emre; Huang, Lan; Ouyang, Qi; Goldberg, Alfred L.; Lu, Ying
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Obituary Dieter Wolf (1941-2023): a life dedicated to understanding protein quality control and the ubiquitin-proteasome system
errEMBO JOURNAL
IF8.3
err2023-05-05
err0
errOAAI
errVarshavsky, Alexander; Finley, Daniel; Goldberg, Alfred L.; Rapoport, Tom A.; Pfirrmann, Thorsten
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errSave
Proteasome inhibitors cause induction of heat shock proteins and trehalose, which together confer thermotolerance in Saccharomyces cerevisiae
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err220
errOAAI
errLee, DH; Goldberg, AL
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errSave
26S proteasomes become stably activated upon heat shock when ubiquitination and protein degradation increase
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-06-15
err11
errOAAI
errLee, Donghoon; Goldberg, Alfred L.
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errSave
Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-05-01
err8
errOAAI
errCollins, Galen Andrew; Sha, Zhe; Kuo, Chueh-Ling; Erbil, Beyza; Goldberg, Alfred L.
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Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy
errBRAIN
IF11.7
err2021-08-11
err10
errOAAI
errVerPlank, Jordan J. S.; Gawron, Joseph; Silvestri, Nicholas J.; Feltri, M. Laura; Wrabetz, Lawrence; Goldberg, Alfred L.
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errSave
Multiple myeloma cells are exceptionally sensitive to heat shock, which overwhelms their proteostasis network and induces apoptosis
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-08-19
err18
errOAAI
errSha, Zhe; Goldberg, Alfred L.
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errSave
cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-06-08
err60
errOAAI
errVerPlank, Jordan J. S.; Tyrkalska, Sylwia D.; Fleming, Angeleen; Rubinsztein, David C.; Goldberg, Alfred L.
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errSave
An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-03-02
err40
errOAAI
errVahidi, Siavash; Ripstein, Zev A.; Juravsky, Jordan B.; Rennella, Enrico; Goldberg, Alfred L.; Mittermaier, Anthony K.; Rubinstein, John L.; Kay, Lewis E.
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errSave
Proteins containing ubiquitin-like (Ubl) domains not only bind to 26S proteasomes but also induce their activation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-02-18
err53
errOAAI
errCollins, Galen A.; Goldberg, Alfred L.
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errSave
Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-10-01
err34
errOAAI
errSha, Zhe; Blyszcz, Tamara; Gonzalez-Prieto, Roman; Vertegaal, Alfred C. O.; Goldberg, Alfred L.
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errSave
SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-06-18
err42
errOAAI
errJiang, Tian-Xia; Zou, Jiang-Bo; Zhu, Qian-Qian; Liu, Cui Hua; Wang, Guang-Fei; Du, Ting-Ting; Luo, Zi-Yu; Guo, Fang; Zhou, Lu-Ming; Liu, Juan-Juan; Zhang, Wensheng; Shu, You-Sheng; Yu, Li; Li, Peng; Ronai, Ze'ev A.; Matsuzawa, Shu-ichi; Goldberg, Alfred L.; Qiu, Xiao-Bo
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PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy
errSCIENCE ADVANCES
IF12.5
err2019-05-03
err51
errOAAI
errZhang, Hanming; Pan, Bo; Wu, Penglong; Parajuli, Nirmal; Rekhter, Mark D.; Goldberg, Alfred L.; Wang, Xuejun
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errSave
26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-02-19
err93
errOAAI
errVerPlank, Jordan J. S.; Lokireddy, Sudarsanareddy; Zhao, Jinghui; Goldberg, Alfred L.
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errSave
UBL domain of Usp14 and other proteins stimulates proteasome activities and protein degradation in cells
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2018-11-28
err55
errOAAI
errKim, Hyoung Tae; Goldberg, Alfred L.
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errSave
ZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2018-09-25
err47
errOAAI
errLee, Donghoon; Takayama, Shinichi; Goldberg, Alfred L.
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errSave
The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2018-06-01
err39
errOAAI
errWeinhaupl, Katharina; Brennich, Martha; Kazmaier, Uli; Lelievre, Joel; Ballell, Lluis; Goldberg, Alfred; Schanda, Paul; Fraga, Hugo
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Rapid induction of p62 and GAB ARA PL1 upon proteasome inhibition promotes survival before autophagy activation
errJOURNAL OF CELL BIOLOGY
IF6.4
err2018-03-13
err80
errOAAI
errSha, Zhe; Schnell, Helena M.; Ruoff, Kerstin; Goldberg, Alfred
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Guido Kroemer
H-index: 283 · Papers: 2.3K
S
Steven P. Gygi
H-index: 195 · Papers: 1.0K
B
Bruce M. Spiegelman
H-index: 186 · Papers: 471
R
Ronald A. DePinho
H-index: 178 · Papers: 907
E
Eric R. Kandel
H-index: 176 · Papers: 630
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