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Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against Rift Valley fever in healthy adults: a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial Leroux-Roels, Isabel; Prajeeth, Chittappen Kandiyil; Aregay, Amare; Nair, Niranjana; Rimmelzwaan, Guus F.; Osterhaus, Albert D. M. E.; Kardinahl, Simone; Pelz, Sabrina; Bauer, Stephan; D'Onofrio, Valentino; Alhatemi, Azhar; Jacobs, Bart; De Boever, Fien; Porrez, Sharon; Waerlop, Gwenn; Punt, Carine; Hendriks, Bart; von Mauw, Ellemieke; van de Water, Sandra; Harders-Westerveen, Jose; Rockx, Barry; van Keulen, Lucien; Kortekaas, Jeroen; Leroux-Roels, Geert; Schreur, Paul J. Wichgers Share Save
Immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: a randomised, double-blind, placebo-controlled, phase 2a trial Leroux-Roels, Isabel; Willems, Paul; Waerlop, Gwenn; Janssens, Yorick; Tourneur, Jessika; De Boever, Fien; Bruhwyler, Jacques; Alhatemi, Azhar; Jacobs, Bart; Nicolas, Florence; Leroux-Roels, Geert; Le Vert, Alexandre Share Save
Safety and immunogenicity of a novel multivalent OspA- based vaccine candidate against Lyme borreliosis: a randomised, phase 1 study in healthy adults Bezay, Nicole; Hochreiter, Romana; Kadlecek, Vera; Wressnigg, Nina; Larcher-Senn, Julian; Klingler, Anton; Dubischar, Katrin; Eder-Lingelbach, Susanne; Leroux-Roels, Isabel; Leroux-Roels, Geert; Bender, Wolfgang Share Save
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Double-Blind, Placebo-Controlled, Dose-Escalating Study Evaluating the Safety and Immunogenicity of an Epitope-Specific Chemically Defined Nanoparticle RSV Vaccine Leroux-Roels, Isabel; Bruhwyler, Jacques; Stergiou, Lilli; Sumeray, Mark; Joye, Jasper; Maes, Cathy; Lambert, Paul-Henri; Leroux-Roels, Geert Share Save
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A single birth dose of Hepatitis B vaccine induces polyfunctional CD4+ T helper cells Strandmark, Julia; Darboe, Alansana; Diray-Arce, Joann; Ben-Othman, Rym; Vignolo, Sofia M.; Rao, Shun; Smolen, Kinga K.; Leroux-Roels, Geert; Idoko, Olubukola T.; Sanchez-Schmitz, Guzman; Ozonoff, Al; Levy, Ofer; Kollmann, Tobias R.; Marchant, Arnaud; Kampmann, Beate; EPIC Consortium Share Save
Harmonization and qualification of intracellular cytokine staining to measure influenza-specific CD4+ T cell immunity within the FLUCOP consortium Begue, Sarah; Waerlop, Gwenn; Salaun, Bruno; Janssens, Michel; Bellamy, Duncan; Cox, Rebecca Jane; Davies, Richard; Gianchecchi, Elena; Medaglini, Donata; Montomoli, Emanuele; Pettini, Elena; Leroux-Roels, Geert; Clement, Frederic; Pagnon, Anke Share Save
A randomized, double-blind, placebo-controlled, dose-escalating phase I trial to evaluate safety and immunogenicity of a plant-produced, bivalent, recombinant norovirus-like particle vaccine Leroux-Roels, Isabel; Maes, Cathy; Joye, Jasper; Jacobs, Bart; Jarczowski, Franziska; Diessner, Andre; Janssens, Yorick; Waerlop, Gwenn; Tamminen, Kirsi; Heinimaki, Suvi; Blazevic, Vesna; Leroux-Roels, Geert; Klimyuk, Victor; Adachi, Hiroshi; Hiruta, Kazuyuki; Thieme, Frank Share Save
Harmonization and qualification of an IFN-? Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium Waerlop, Gwenn; Leroux-Roels, Geert; Lambe, Teresa; Bellamy, Duncan; Medaglini, Donata; Pettini, Elena; Cox, Rebecca Jane; Trieu, Mai-Chi; Davies, Richard; Bredholt, Geir; Montomoli, Emanuele; Gianchecchi, Elena; Clement, Frederic Share Save
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Randomized, Double-Blind, Reference-Controlled, Phase 2a Study Evaluating the Immunogenicity and Safety of OVX836, A Nucleoprotein-Based Influenza Vaccine Leroux-Roels, Isabel; Waerlop, Gwenn; Tourneur, Jessika; De Boever, Fien; Maes, Catherine; Bruhwyler, Jacques; Guyon-Gellin, Delphine; Moris, Philippe; Del Campo, Judith; Willems, Paul; Leroux-Roels, Geert; Le Vert, Alexandre; Nicolas, Florence Share Save
A Role for B Cells to Transmit Hepatitis C Virus Infection Desombere, Isabelle; Van Houtte, Freya; Farhoudi, Ali; Verhoye, Lieven; Buysschaert, Caroline; Gijbels, Yvonne; Couvent, Sibyl; Swinnen, Wilfried; Van Vlierberghe, Hans; Elewaut, Andre; Magri, Andrea; Stamataki, Zania; Meuleman, Philip; McKeating, Jane A.; Leroux-Roels, Geert Share Save
Immunogenicity and safety of a tri-antigenic versus a mono-antigenic hepatitis B vaccine in adults (PROTECT): a randomised, double-blind, phase 3 trial Vesikari, Timo; Langley, Joanne M.; Segall, Nathan; Ward, Brian J.; Cooper, Curtis; Poliquin, Guillaume; Smith, Bruce; Gantt, Soren; McElhaney, Janet E.; Dionne, Marc; van Damme, Pierre; Leroux-Roels, Isabel; Leroux-Roels, Geert; Machluf, Nathalie; Spaans, Johanna N.; Yassin-Rajkumar, Bebi; Anderson, David E.; Popovic, Vlad; Diaz-Mitoma, Francisco Share Save
Antibody avidity, persistence, and response to antigen recall: comparison of vaccine adjuvants Budroni, Sonia; Buricchi, Francesca; Cavallone, Andrea; Bourguignon, Patricia; Caubet, Magalie; Dewar, Vincent; D'Oro, Ugo; Finco, Oretta; Garcon, Nathalie; El Idrissi, Mohamed; Janssens, Michel; Leroux-Roels, Geert; Marchant, Arnaud; Schwarz, Tino; Van Damme, Pierre; Volpini, Gianfranco; van der Most, Robbert; Didierlaurent, Arnaud M.; Burny, Wivine Share Save
Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials De Coster, Ilse; Leroux-Roels, Isabel; Bandyopadhyay, Ananda S.; Gast, Christopher; Withanage, Kanchanamala; Steenackers, Katie; De Smedt, Philippe; Aerssens, Annelies; Leroux-Roels, Geert; Oberste, M. Steven; Konopka-Anstadt, Jennifer L.; Weldon, William C.; Fix, Alan; Konz, John; Wahid, Rahnuma; Modlin, John; Clemens, Ralf; Clemens, Sue Ann Costa; Bachtiar, Novilia S.; Van Damme, Pierre Share Save