David R. Linden - Publications, H-index & Citations

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David R. Linden

mayo clinic

39H-index

219Paper Count

7.5KCitation Count

Published Papers 62

Publication Date

Changes in interstitial cells of Cajal calcium activity in a diabetic mouse model of delayed gastric emptying

The Journal of Physiology

IF0

2026-05-30

PREAI

Elisia Maalouf; Xin-yi Chai; Jack A. Patraw; Gianluca Cipriani; David R. Linden; Cheryl E. Bernard; Gianrico Farrugia; Peng Du; Kristen M. Smith-Edwards; Madhusudan Grover

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AN OPEN-LABEL TRIAL OF EFFECTS OF VARENICLINE IN NON-CONSTIPATION IRRITABLE BOWEL SYNDROME AND PAIN

Clinical Gastroenterology and Hepatology

IF12

2026-04-25

PREAI

Ayah Matar; Irene Busciglio; Deborah Eckert; David R. Linden; W. Scott Harmsen; Michael Camilleri

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Distinct human small intestinal microbiome communities underlie visceral hypersensitivity in a humanized mouse model

Journal of Clinical Investigation

IF13.6

2025-12-15

OAAI

Comba, Isin Y.; Louwies, Tijs; Mars, Ruben A. T.; Xiao, Yang; Sekhon, Prabhjot Kaur; Edwards, Brian S.; Willits, Adam; Shields-Cutler, Robin R.; Bellampalli, Shreya; Mercado-Perez, Arnaldo; Tienter, Dennis R.; Till, Lisa M.; Linden, David R.; Farrugia, Gianrico; Beyder, Arthur; Smith-Edwards, Kristen M.; Kashyap, Purna C.

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Sex-Dependent Circadian Rhythm Impact on Murine Gastrointestinal Transit

neurogastroenterology and motility

IF0

2025-07-08

PREAI

Shreya S. Bellampalli; Gennadiy Fonar; Michael Grynyshyn; Arnaldo Mercado-Perez; Karan H. Muchhala; Gianrico Farrugia; Aleksey V. Matveyenko; David R. Linden; Arthur Beyder

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Circadian rhythm and whole gut transit in mice

NEUROGASTROENTEROLOGY AND MOTILITY

IF2.9

2024-02-23

OAAI

Laible, Emma; Wegner, Andrew; Knutson, Kaitlyn; Kacmaz, Halil; Garramone, Gwyneth K.; Gogineni, Kamalika; Matveyenko, Aleksey; Linden, David R.; Farrugia, Gianrico; Beyder, Arthur

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Hypoxia-Inducible Factor 1a Stabilization Restores Epigenetic Control of Nitric Oxide Synthase 1 Expression and Reverses Gastroparesis in Female Diabetic Mice

GASTROENTEROLOGY

IF25.1

2023-12-01

PREAI

Gao, Fei; Hayashi, Yujiro; Saravanaperumal, Siva Arumugam; Gajdos, Gabriella B.; Syed, Sabriya A.; Bhagwate, Aditya, V; Ye, Zhenqing; Zhong, Jian; Zhang, Yuebo; Choi, Egan L.; Kvasha, Sergiy M.; Kaur, Jagneet; Paradise, Brooke D.; Cheng, Liang; Simone, Brandon W.; Wright, Alec M.; Kellogg, Todd A.; Kendrick, Michael L.; McKenzie, Travis J.; Sun, Zhifu; Yan, Huihuang; Yu, Chuanhe; Bharucha, Adil E.; Linden, David R.; Lee, Jeong-Heon; Ordog, Tamas

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Modeling gut neuro-epithelial connections in a novel microfluidic device

MICROSYSTEMS & NANOENGINEERING

IF9.9

2023-11-14

OAAI

de Hoyos-Vega, Jose M.; Yu, Xi; Gonzalez-Suarez, Alan M.; Chen, Sisi; Mercado-Perez, Arnaldo; Krueger, Eugene; Hernandez, Jeric; Fedyshyn, Yaroslav; Druliner, Brooke R.; Linden, David R.; Beyder, Arthur; Revzin, Alexander

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THE ADDITIVE VALUE OF BRAIN LIFESTYLE IN THE EXPLANATORY ABILITY OF POLYGENIC RISK PROFILES ON COGNITIVE PERFORMANCE IN AGING INDIVIDUALS

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2023-10-01

PREAI

Zhang, Yidan; Guloksuz, Sinan; Stehouwer, Coen; Greevenbroek, Marleen; Kohler, Sebastian; Eussen, Simone; Bosma, Hans; Boxtel, Martin; Schram, Miranda; Linden, David; Rutten, Bart; Blokland, Gabriella

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Adeno-associated virus-9 reverses delayed gastric emptying of solids in diabetic mice

NEUROGASTROENTEROLOGY AND MOTILITY

IF2.9

2023-09-13

OAAI

Li, Xiaojie; Ji, Sihan; Cipriani, Gianluca; Hillestad, Matthew L.; Eisenman, Seth T.; Barry, Michael A.; Nath, Karl A.; Linden, David R.; Wright, Alec; Alasfoor, Shefaa; Grover, Madhusudan; Sha, Lei; Hsi, Linda C.; Farrugia, Gianrico

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Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2023-01-01

OAAI

Nguyen, Vy Truong Thuy; Taheri, Negar; Choi, Egan L.; Kellogg, Todd A.; Linden, David R.; Hayashi, Yujiro

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Specialized Mechanosensory Epithelial Cells in Mouse Gut Intrinsic Tactile Sensitivity

GASTROENTEROLOGY

IF25.1

2022-02-01

OAAI

Treichel, Anthony J.; Finholm, Isabelle; Knutson, Kaitlyn R.; Alcaino, Constanza; Whiteman, Sara T.; Brown, Matthew R.; Matveyenko, Aleksey; Wegner, Andrew; Kacmaz, Halil; Mercado-Perez, Arnaldo; Gajdos, Gabriella Bedekovicsne; Ordog, Tamas; Grover, Madhusudan; Szurszewski, Joseph; Linden, David R.; Farrugia, Gianrico; Beyder, Arthur

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Passive siRNA transfection method for gene knockdown in air-liquid interface airway epithelial cell cultures

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2021-07-01

OAAI

Bartman, Colleen M.; Stelzig, Kimberly E.; Linden, David R.; Prakash, Y. S.; Chiarella, Sergio E.

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Bicarbonate ion transport by the electrogenic Na+/HCO3- cotransporter, NBCe1, is required for normal electrical slow-wave activity in mouse small intestine

NEUROGASTROENTEROLOGY AND MOTILITY

IF2.9

2021-04-10

OAAI

Zhao, Wenchang; Zhang, Liwen; Ermilov, Leonid G.; Aguilar, Maria Gabriela Colmenares; Linden, David R.; Eisenman, Seth T.; Romero, Michael F.; Farrugia, Gianrico; Sha, Lei; Gibbons, Simon J.

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Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial of Cell of Cajal Depletion During Aging

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2021-01-01

OAAI

Hayashi, Yujiro; Asuzu, David T.; Bardsley, Michael R.; Gajdos, Gabriella B.; Kvasha, Sergiy M.; Linden, David R.; Nagy, Rea A.; Saravanaperumal, Siva Arumugam; Syed, Sabriya A.; Toyomasu, Yoshitaka; Yan, Huihuang; Chini, Eduardo N.; Gibbons, Simon J.; Kellogg, Todd A.; Khazaie, Khashayarsha; Kuro-o, Makoto; Netto, Jair Machado Espindola; Singh, Mahendra Pal; Tidball, James G.; Wehling-Henricks, Michelle; Farrugia, Gianrico; Ordog, Tamas

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A simple automated approach to measure mouse whole gut transit

NEUROGASTROENTEROLOGY AND MOTILITY

IF2.9

2020-09-30

OAAI

Kacmaz, Halil; Alto, Alecia; Knutson, Kaitlyn; Linden, David R.; Gibbons, Simon J.; Farrugia, Gianrico; Beyder, Arthur

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Identification of intrinsic primary afferent neurons in mouse jejunum

NEUROGASTROENTEROLOGY AND MOTILITY

IF2.9

2020-09-28

OAAI

Melo, Carina Guimaraes de Souza; Nicolai, Evan N.; Alcaino, Constanza; Cassmann, Tiffany J.; Whiteman, Sara T.; Wright, Alec M.; Miller, Katie E.; Gibbons, Simon J.; Beyder, Arthur; Linden, David R.

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Hydrogen sulfide, oxygen, and calcium regulation in developing human airway smooth muscle

FASEB JOURNAL

IF4.2

2020-08-10

OAAI

Bartman, Colleen M.; Schiliro, Marta; Helan, Martin; Prakash, Y. S.; Linden, David; Pabelick, Christina

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Duodenal mucosal secretory disturbances in functional dyspepsia

NEUROGASTROENTEROLOGY AND MOTILITY

IF2.9

2020-08-09

OAAI

Narayanan, Susrutha Puthanmadhom; Linden, David R.; Peters, Stephanie A.; Desai, Anshuman; Kuwelker, Saatchi; O'Brien, Daniel; Smyrk, Thomas J.; Graham, Rondell P.; Grover, Madhusudan; Bharucha, Adil E.

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Epithelial Mechanosensitive Ion Channel Piezo2 Contributes to Pressure-Induced Epithelial Chloride Secretion in Mouse Colon

FASEB JOURNAL

IF4.2

2020-04-21

PREAI

Knutson, Kaitlyn; Finholm, Isabelle; Treichel, Anthony; Whiteman, Sara; Linden, David; Grover, Madhusudan; Farrugia, Gianrico; Beyder, Arthur

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Enteric Glial Networks Visualized using SOX10 Fluorescent Reporter in Optically-Cleared Full Thickness Intestinal Tissues

FASEB JOURNAL

IF4.2

2020-04-20

PREAI

Betageri, Kalpana; Wright, Alec; Beyder, Arthur; Linden, David

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Research Directions