Not logged in Oxidised Apolipoprotein Peptidome Characterises Metabolic Dysfunction-Associated Steatotic Liver Disease Mocciaro, Gabriele; George, Amy L.; Allison, Michael; Frontini, Mattia; Huang-Doran, Isabel; Reiman, Frank; Gribble, Fiona; Griffin, Julian L.; Vidal-Puig, Antonio; Azzu, Vian; Kay, Richard; Vacca, Michele Share Save
Characterization of six clinical drugs and dietary intervention in the nonobese CDAA-HFD mouse model of MASH and progressive fibrosis Nielsen, MH; Nohr-Meldgaard, J; Mollerhoj, MB; Oró, D; Pors, SE; Andersen, MW; Kamzolas, I; Petsalaki, E; Vacca, M; Harder, LM; Perfield, JW; Veidal, S; Hansen, HH; Feigh, M Share Save
Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity Sowton, AP; Holzner, LMW; Krause, FN; Baxter, R; Mocciaro, G; Krzyzanska, DK; Minnion, M; O'Brien, KA; Harrop, MC; Darwin, PM; Thackray, BD; Vacca, M; Feelisch, M; Griffin, JL; Murray, AJ Share Save
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SMIM1 absence is associated with reduced energy expenditure and excess weight Stefanucci, Luca; Moslemi, Camous; Tome, Ana R.; Virtue, Samuel; Bidault, Guillaume; Gleadall, Nicholas S.; Watson, Laura P. E.; Kwa, Jing E.; Burden, Frances; Farrow, Samantha; Chen, Ji; Vosa, Urmo; Burling, Keith; Walker, Lindsay; Ord, John; Barker, Peter; Warner, James; Frary, Amy; Renhstrom, Karola; Ashford, Sofie E.; Piper, Jo; Biggs, Gail; Erber, Wendy N.; Hoffman, Gary J.; Schoenmakers, Nadia; Erikstrup, Christian; Rieneck, Klaus; Dziegiel, Morten H.; Ullum, Henrik; Azzu, Vian; Vacca, Michele; Aparicio, Hugo Javier; Hui, Qin; Cho, Kelly; Sun, Yan, V; Wilson, Peter W.; Bayraktar, Omer A.; Vidal-Puig, Antonio; Ostrowski, Sisse R.; Astle, William J.; Olsson, Martin L.; Storry, Jill R.; Pedersen, Ole B.; Ouwehand, Willem H.; Chatterjee, Krishna; Vuckovic, Dragana; Frontini, Mattia Share Save
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) Vacca, Michele; Kamzolas, Ioannis; Harder, Lea Morch; Oakley, Fiona; Trautwein, Christian; Hatting, Maximilian; Ross, Trenton; Bernardo, Barbara; Oldenburger, Anouk; Hjuler, Sara Toftegaard; Ksiazek, Iwona; Linden, Daniel; Schuppan, Detlef; Rodriguez-Cuenca, Sergio; Tonini, Maria Manuela; Castaneda, Tamara R.; Kannt, Aimo; Rodrigues, Cecilia M. P.; Cockell, Simon; Govaere, Olivier; Daly, Ann K.; Allison, Michael; de Lichtenberg, Kristian Honnens; Kim, Yong Ook; Lindblom, Anna; Oldham, Stephanie; Andreasson, Anne-Christine; Schlerman, Franklin; Marioneaux, Jonathon; Sanyal, Arun; Afonso, Marta B.; Younes, Ramy; Amano, Yuichiro; Friedman, Scott L.; Wang, Shuang; Bhattacharya, Dipankar; Simon, Eric; Paradis, Valerie; Burt, Alastair; Grypari, Ioanna Maria; Davies, Susan; Driessen, Ann; Yashiro, Hiroaki; Pors, Susanne; Andersen, Maja Worm; Feigh, Michael; Yunis, Carla; Bedossa, Pierre; Stewart, Michelle; Cater, Heather L.; Wells, Sara; Schattenberg, Joern M.; Anstee, Quentin M.; Tiniakos, Dina; Perfield, James W.; Petsalaki, Evangelia; Davidsen, Peter; Vidal-Puig, Antonio; Anstee, Quentin M.; Daly, Ann K.; Cockell, Simon; Tiniakos, Dina; Bedossa, Pierre; Burt, Alastair; Oakley, Fiona; Cordell, Heather J.; Day, Christopher P.; Wonders, Kristy; Missier, Paolo; McTeer, Matthew; Vale, Luke; Oluboyede, Yemi; Breckons, Matt; Boyle, Jo; Bossuyt, Patrick M.; Zafarmand, Hadi; Vali, Yasaman; Lee, Jenny; Nieuwdorp, Max; Holleboom, Adriaan G.; Angelakis, Athanasios; Verheij, Joanne; Ratziu, Vlad; Clement, Karine; Patino-Navarrete, Rafael; Pais, Raluca; Paradis, Valerie; Schuppan, Detlef; Schattenberg, Joern M.; Surabattula, Rambabu; Myneni, Sudha; Kim, Yong Ook; Straub, Beate K.; Vidal-Puig, Antonio; Vacca, Michele; Rodrigues-Cuenca, Sergio; Allison, Mike; Kamzolas, Ioannis; Petsalaki, Evangelia; Campbell, Mark; Lelliott, Chris J.; Davies, Susan; Oresic, Matej; Hyotylainen, Tuulia; McGlinchey, Aidan; Mato, Jose M.; Millet, Oscar; Dufour, Jean-Francois; Berzigotti, Annalisa; Masoodi, Mojgan; Lange, Naomi F.; Pavlides, Michael; Harrison, Stephen; Neubauer, Stefan; Cobbold, Jeremy; Mozes, Ferenc; Akhtar, Salma; Olodo-Atitebi, Seliat; Banerjee, Rajarshi; Shumbayawonda, Elizabeth; Dennis, Andrea; Andersson, Anneli; Wigley, Ioan; Romero-Gomez, Manuel; Gomez-Gonzalez, Emilio; Ampuero, Javier; Castell, Javier; Gallego-Duran, Rocio; Fernandez-Lizaranzu, Isabel; Montero-Vallejo, Rocio; Karsdal, Morten; Rasmussen, Daniel Guldager Kring; Leeming, Diana Julie; Sinisi, Antonia; Musa, Kishwar; Sandt, Estelle; Tonini, Maria Manuela; Bugianesi, Elisabetta; Rosso, Chiara; Armandi, Angelo; Marra, Fabio; Gastaldelli, Amalia; Svegliati, Gianluca; Boursier, Jerome; Francque, Sven; Vonghia, Luisa; Verrijken, An; Dirinck, Eveline; Driessen, Ann; Ekstedt, Mattias; Kechagias, Stergios; Yki-Jarvinen, Hannele; Porthan, Kimmo; Arola, Johanna; van Mil, Saskia; Papatheodoridis, George; Cortez-Pinto, Helena; Silva, Ana Paula; Rodrigues, Cecilia M. P.; Valenti, Luca; Pelusi, Serena; Petta, Salvatore; Pennisi, Grazia; Miele, Luca; Liguori, Antonio; Geier, Andreas; Rau, Monika; Trautwein, Christian; Reissing, Johanna; Aithal, Guruprasad P.; Francis, Susan; Palaniyappan, Naaventhan; Bradley, Christopher; Hockings, Paul; Schneider, Moritz; Newsome, Philip N.; Hubscher, Stefan; Wenn, David; Magnanensi, Jeremy; Trylesinski, Aldo; Mayo, Rebeca; Alonso, Cristina; Duffin, Kevin; Perfield, James W.; Chen, Yu; Hartman, Mark L.; Yunis, Carla; Miller, Melissa; Chen, Yan; McLeod, Euan James; Ross, Trenton; Bernardo, Barbara; Schoelch, Corinna; Ertle, Judith; Younes, Ramy; Coxson, Harvey; Simon, Eric; Gogain, Joseph; Ostroff, Rachel; Alexander, Leigh; Biegel, Hannah; Kjaer, Mette Skalshoi; Harder, Lea Morch; Al-Sari, Naba; Veidal, Sanne Skovgard; Oldenburger, Anouk; Ellegaard, Jens; Balp, Maria-Magdalena; Jennings, Lori; Martic, Miljen; Loffler, Jurgen; Applegate, Douglas; Torstenson, Richard; Linden, Daniel; Fournier-Poizat, Celine; Llorca, Anne; Kalutkiewicz, Michael; Pepin, Kay; Ehman, Richard; Horan, Gerald; Ho, Gideon; Tai, Dean; Chng, Elaine; Xiao, Teng; Patterson, Scott D.; Billin, Andrew; Doward, Lynda; Twiss, James; Thakker, Paresh; Derdak, Zoltan; Yashiro, Hiroaki; Landgren, Henrik; Lackner, Carolin; Gouw, Annette; Hytiroglou, Prodromos; Govaere, Olivier; Brass, Clifford Share Save
Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models Caon, Elisabetta; Martins, Maria; Hodgetts, Harry; Blanken, Lieke; Vilia, Maria Giovanna; Levi, Ana; Thanapirom, Kessarin; Al-Akkad, Walid; Abu-Hanna, Jeries; Baselli, Guido; Hall, Andrew R.; Luong, Tu Vinh; Taanman, Jan-Willem; Vacca, Michele; Valenti, Luca; Romeo, Stefano; Mazza, Giuseppe; Pinzani, Massimo; Rombouts, Krista Share Save
Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL) Mocciaro, Gabriele; Allison, Michael; Jenkins, Benjamin; Azzu, Vian; Huang-Doran, Isabel; Herrera-Marcos, Luis Vicente; Hall, Zoe; Murgia, Antonio; Susan, Davies; Frontini, Mattia; Vidal-Puig, Antonio; Koulman, Albert; Griff, Julian L.; Vacca, Michele Share Save
Genome-wide association study of non- alcoholic fatty liver and steatohepatitis in a histologically characterised cohort( vol 73, pp 505-515 , 2020 ) Anstee, Quentin M.; Darlay, Rebecca; Cockell, Simon; Meroni, Marica; Govaere, Olivier; Tiniakos, Dina; Burt, Alastair D.; Bedossa, Pierre; Palmer, Jeremy; Liu, Yang-Lin; Aithal, Guruprasad P.; Allison, Michael; Yki-Jarvinen, Hannele; Vacca, Michele; Dufour, Jean-Francois; Invernizzi, Pietro; Prati, Daniele; Ekstedt, Mattias; Kechagias, Stergios; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Clement, Karine; Ratziu, Vlad; Schattenberg, Joern M.; Valenti, Luca; Day, Christopher P.; Cordell, Heather J.; Daly, Ann K. Share Save
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Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease Govaere, Olivier; Petersen, Sine Kragh; Martinez-Lopez, Nuria; Wouters, Jasper; Van Haele, Matthias; Mancina, Rosellina M.; Jamialahmadi, Oveis; Bilkei-Gorzo, Orsolya; Lassen, Pierre Bel; Darlay, Rebecca; Peltier, Julien; Palmer, Jeremy M.; Younes, Ramy; Tiniakos, Dina; Aithal, Guruprasad P.; Allison, Michael; Vacca, Michele; Goransson, Melker; Berlinguer-Palmini, Rolando; Clark, James E.; Drinnan, Michael J.; Yki-Jarvinen, Hannele; Dufour, Jean-Francois; Ekstedt, Mattias; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Schattenberg, Jorn M.; Day, Christopher P.; Cordell, Heather J.; Topal, Baki; Clement, Karine; Romeo, Stefano; Ratziu, Vlad; Roskams, Tania; Daly, Ann K.; Anstee, Quentin M.; Trost, Matthias; Hartlova, Anetta Share Save
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle McNally, Ben D.; Ashley, Dean F.; Haenschke, Lea; Daou, Helene N.; Watt, Nicole T.; Murfitt, Steven A.; MacCannell, Amanda D., V; Whitehead, Anna; Bowen, T. Scott; Sanders, Francis W. B.; Vacca, Michele; Witte, Klaus K.; Davies, Graeme R.; Bauer, Reinhard; Griffin, Julian L.; Roberts, Lee D. Share Save
Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes Seyres, Denis; Cabassi, Alessandra; Lambourne, John J.; Burden, Frances; Farrow, Samantha; McKinney, Harriet; Batista, Joana; Kempster, Carly; Pietzner, Maik; Slingsby, Oliver; Thong Huy Cao; Quinn, Paulene A.; Stefanucci, Luca; Sims, Matthew C.; Rehnstrom, Karola; Adams, Claire L.; Frary, Amy; Erguener, Bekir; Kreuzhuber, Roman; Mocciaro, Gabriele; D'Amore, Simona; Koulman, Albert; Grassi, Luigi; Griffin, Julian L.; Ng, Leong Loke; Park, Adrian; Savage, David B.; Langenberg, Claudia; Bock, Christoph; Downes, Kate; Wareham, Nicholas J.; Allison, Michael; Vacca, Michele; Kirk, Paul D. W.; Frontini, Mattia Share Save
RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state Belenguer, German; Mastrogiovanni, Gianmarco; Pacini, Clare; Hall, Zoe; Dowbaj, Anna M.; Arnes-Benito, Robert; Sljukic, Aleksandra; Prior, Nicole; Kakava, Sofia; Bradshaw, Charles R.; Davies, Susan; Vacca, Michele; Saeb-Parsy, Kourosh; Koo, Bon-Kyoung; Huch, Meritxell Share Save
β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development Rao, Shuyun; Yang, Xiaochun; Ohshiro, Kazufumi; Zaidi, Sobia; Wang, Zhanhuai; Shetty, Kirti; Xiang, Xiyan; Hassan, Md Imtaiyaz; Mohammad, Taj; Latham, Patricia S.; Bao-Ngoc Nguyen; Wong, Linda; Yu, Herbert; Al-Abed, Yousef; Mishra, Bibhuti; Vacca, Michele; Guenigault, Gareth; Allison, Michael E. D.; Vidal-Puig, Antonio; Benhammou, Jihane N.; Alvarez, Marcus; Pajukanta, Paivi; Pisegna, Joseph R.; Mishra, Lopa Share Save
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression Azzu, Vian; Vacca, Michele; Kamzolas, Ioannis; Hall, Zoe; Leslie, Jack; Carobbio, Stefania; Virtue, Samuel; Davies, Susan E.; Lukasik, Agnes; Dale, Martin; Bohlooly-Y, Mohammad; Acharjee, Animesh; Linden, Daniel; Bidault, Guillaume; Petsalaki, Evangelia; Griffin, Julian L.; Oakley, Fiona; Allison, Michael E. D.; Vidal-Puig, Antonio Share Save
Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort (vol 12, pg 505, 2020) Anstee, Quentin M.; Darlay, Rebecca; Cockell, Simon; Meroni, Marica; Govaere, Olivier; Tiniakos, Dina; Burt, Alastair D.; Bedossa, Pierre; Palmer, Jeremy; Liu, Yang-Lin; Aithal, Guruprasad P.; Allison, Michael; Yki-Jarvinen, Hannele; Vacca, Michele; Dufour, Jean-Francois; Invernizzi, Pietro; Prati, Daniele; Ekstedt, Mattias; Kechagias, Stergios; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Clement, Karine; Ratziu, Vlad; Schattenberg, Jorn M.; Valenti, Luca; Day, Christopher P.; Cordell, Heather J.; Daly, Ann K. Share Save
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis Govaere, Olivier; Cockell, Simon; Tiniakos, Dina; Queen, Rachel; Younes, Ramy; Vacca, Michele; Alexander, Leigh; Ravaioli, Federico; Palmer, Jeremy; Petta, Salvatore; Boursier, Jerome; Rosso, Chiara; Johnson, Katherine; Wonders, Kristy; Day, Christopher P.; Ekstedt, Mattias; Oresic, Matej; Darlay, Rebecca; Cordell, Heather J.; Marra, Fabio; Vidal-Puig, Antonio; Bedossa, Pierre; Schattenberg, Joern M.; Clement, Karine; Allison, Michael; Bugianesi, Elisabetta; Ratziu, Vlad; Daly, Ann K.; Anstee, Quentin M. Share Save
The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production Prins, Daniel; Park, Hyun Jung; Watcham, Sam; Li, Juan; Vacca, Michele; Bastos, Hugo P.; Gerbaulet, Alexander; Vidal-Puig, Antonio; Gottgens, Berthold; Green, Anthony R. Share Save
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