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SaveMULTI-OMICS INTEGRATION IN POST-SURGERY RESIDUAL TUMOR UNVEILS INTENSE MICROENVIRONMENT RESHAPING
Ballestin, A.; Reveilles, J.; Thomas, A.; Pichol-Thievend, C.; Anezo, O.; Bourmeau, G.; Ribecco, V; Blanchard, B.; Chemkhi, A.; Daubon, T.; Isambert, H.; Cavalli, F. M.; Seano, G. Share Save NEUROSURGERY IN GLIOBLASTOMA INDUCES CELL PLASTICITY, THERAPY RESISTANCE AND IMMUNOSUPPRESSION BY ISCHEMIC HYPOXIABallestin, A.; Reveilles, J.; Ribecco, V; Pichol-Thievend, C.; Thomas, A.; Anezo, O.; Bourmeau, G.; Borst, G. R.; Delobel, T.; Chemkhi, A.; Alanio, C.; Ballesta, A.; Isambert, H.; Cavalli, F. M.; Heiland, D.; Golebiewska, A.; Daubon, T.; Binder, Z. A.; van Rheenen, J.; Roncaroli, F.; Joseph, K.; Ravi, V. M.; Seano, G. Share Save SURGICAL RESECTION OF GLIOBLASTOMA INDUCES IMMUNOSUPPRESSIONReveilles, J.; Ballestin, A.; Pichol-Thievend, C.; Thomas, A.; Ribecco, V; Anezo, O.; Bourmeau, G.; Blanchard, B.; Cavalli, F. M.; Borst, G. R.; Alanio, C.; Heiland, D.; Golebiewska, A.; Binder, Z. A.; van Rheenen, J.; Roncaroli, F.; Joseph, K.; Ravi, V. M.; Seano, G. Share Save Share Save ZIC1 is a context-dependent medulloblastoma driver in the rhombic lipLee, John J. Y.; Tao, Ran; You, Zhen; Haldipur, Parthiv; Erickson, Anders W.; Farooq, Hamza; Hendriske, Liam D.; Abeysundara, Namal; Richman, Cory M.; Wang, Evan Y.; Das Gupta, Neha; Hadley, Jennifer; Batts, Melissa; Mount, Christopher W.; Wu, Xiaochong; Rasnitsyn, Alex; Bailey, Swneke; Cavalli, Florence M. G.; Morrissy, Sorana; Garzia, Livia; Michealraj, Kulandaimanuvel Antony; Visvanathan, Abhi; Fong, Vernon; Palotta, Jonelle; Suarez, Raul; Livingston, Bryn G.; Liu, Miao; Luu, Betty; Daniels, Craig; Loukides, James; Bendel, Anne; French, Pim J.; Kros, Johan M.; Kool, Marcel; Chico Ponce de Leon, Fernando; Perezpena-Diazconti, Mario; Lach, Boleslaw; Singh, Sheila K.; Leary, Sarah E. S.; Cho, Byung-Kyu; Kim, Seung-Ki; Wang, Kyu-Chang; Lee, Ji-Yeoun; Tominaga, Teiji; Weiss, William A.; Phillips, Joanna J.; Dai, Shizhong; Zadeh, Gelareh; Saad, Ali G.; Bognar, Laszlo; Klekner, Almos; Pollack, Ian F.; Hamilton, Ronald L.; Ra, Young-shin; Grajkowska, Wieslawa A.; Perek-Polnik, Marta; Thompson, Reid C.; Kenney, Anna M.; Cooper, Michael K.; Mack, Stephen C.; Jabado, Nada; Lupien, Mathieu; Ramaswamy, Vijay; Suva, Mario L.; Suzuki, Hiromichi; Millen, Kathleen J.; Huang, L. Frank Share Save VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistancePichol-Thievend, Cathy; Anezo, Oceane; Pettiwala, Aafrin M.; Bourmeau, Guillaume; Montagne, Remi; Lyne, Anne-Marie; Guichet, Pierre-Olivier; Deshors, Pauline; Ballestin, Alberto; Blanchard, Benjamin; Reveilles, Juliette; Ravi, Vidhya M.; Joseph, Kevin; Heiland, Dieter H.; Julien, Boris; Leboucher, Sophie; Besse, Laetitia; Legoix, Patricia; Dingli, Florent; Liva, Stephane; Loew, Damarys; Giani, Elisa; Ribecco, Valentino; Furumaya, Charita; Marcos-Kovandzic, Laura; Masliantsev, Konstantin; Daubon, Thomas; Wang, Lin; Diaz, Aaron A.; Schnell, Oliver; Beck, Jugen; Servant, Nicolas; Karayan-Tapon, Lucie; Cavalli, Florence M. G.; Seano, Giorgio Share Save GLIOBLASTOMA VESSEL CO-OPTION AND TRANSITION TO A RESISTANT CELL STATE ARE INDUCED BY CHEMORADIATIONPichol-Thievend, C.; Anezo, O.; Pettiwala, A. M.; Bourmeau, G.; Montagne, R.; Lyne, A.; Guichet, P.; Deshors, P.; Ballestin, A.; Blanchard, B.; Reveilles, J.; Ravi, V. M.; Joseph, K.; Heiland, D. H.; Julien, B.; Leboucher, S.; Besse, L.; Legoix, P.; Dingli, F.; Liva, S.; Furumaya, C.; Marcos, L. Kovandzic; Masliantsev, K.; Daubon, T.; Schnell, O.; Beck, J.; Servant, N.; Karayan-Tapon, L.; Cavalli, F. M. G.; Seano, G. Share Save ABL1 and ABL2 promote medulloblastoma leptomeningeal disseminationJones, Jill K.; Zhang, Hengshan; Lyne, Anne-Marie; Cavalli, Florence M. G.; Hassen, Wafa E.; Stevenson, Kevin; Kornahrens, Reb; Yang, Yuanfan; Li, Sean; Dell, Samuel; Reitman, Zachary J.; Herndon, James E.; Hoj, Jacob; Pendergast, Ann Marie; Thompson, Eric M. Share Save Share Save Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma (vol 26, pg 720, 2020)Donovan, Laura K.; Delaidelli, Alberto; Joseph, Sujith K.; Bielamowicz, Kevin; Fousek, Kristen; Holgado, Borja L.; Manno, Alex; Srikanthan, Dilakshan; Gad, Ahmed Z.; Van Ommeren, Randy; Przelicki, David; Richman, Cory; Ramaswamy, Vijay; Daniels, Craig; Pallota, Jonelle G.; Douglas, Tajana; Joynt, Alyssa C. M.; Haapasalo, Joonas; Nor, Carolina; Vladoiu, Maria C.; Kuzan-Fischer, Claudia M.; Garzia, Livia; Mack, Stephen C.; Varadharajan, Srinidhi; Baker, Matthew L.; Hendrikse, Liam; Ly, Michelle; Kharas, Kaitlin; Balin, Polina; Wu, Xiaochong; Qin, Lei; Huang, Ning; Stucklin, Ana Guerreiro; Morrissy, A. Sorana; Cavalli, Florence M. G.; Luu, Betty; Suarez, Raul; De Antonellis, Pasqualino; Michealraj, Antony; Rastan, Avesta; Hegde, Meenakshi; Komosa, Martin; Sirbu, Olga; Kumar, Sachin A.; Abdullaev, Zied; Faria, Claudia C.; Yip, Stephen; Hukin, Juliette; Tabori, Uri; Hawkins, Cynthia; Aldape, Ken; Daugaard, Mads; Maris, John M.; Sorensen, Poul H.; Ahmed, Nabil; Taylor, Michael D. Share Save The transcriptional landscape of Shh medulloblastomaSkowron, Patryk; Farooq, Hamza; Cavalli, Florence M. G.; Morrissy, A. Sorana; Ly, Michelle; Hendrikse, Liam D.; Wang, Evan Y.; Djambazian, Haig; Zhu, Helen; Mungall, Karen L.; Trinh, Quang M.; Zheng, Tina; Dai, Shizhong; Stucklin, Ana S. Guerreiro; Vladoiu, Maria C.; Fong, Vernon; Holgado, Borja L.; Nor, Carolina; Wu, Xiaochong; Abd-Rabbo, Diala; Berube, Pierre; Wang, Yu Chang; Luu, Betty; Suarez, Raul A.; Rastan, Avesta; Gillmor, Aaron H.; Lee, John J. Y.; Zhang, Xiao Yun; Daniels, Craig; Dirks, Peter; Malkin, David; Bouffet, Eric; Tabori, Uri; Loukides, James; Doz, Francois P.; Bourdeaut, Franck; Delattre, Olivier O.; Masliah-Planchon, Julien; Ayrault, Olivier; Kim, Seung-Ki; Meyronet, David; Grajkowska, Wieslawa A.; Carlotti, Carlos G.; de Torres, Carmen; Mora, Jaume; Eberhart, Charles G.; Van Meir, Erwin G.; Kumabe, Toshihiro; French, Pim J.; Kros, Johan M.; Jabado, Nada; Lach, Boleslaw; Pollack, Ian F.; Hamilton, Ronald L.; Rao, Amulya A. Nageswara; Giannini, Caterina; Olson, James M.; Bognar, Laszlo; Klekner, Almos; Zitterbart, Karel; Phillips, Joanna J.; Thompson, Reid C.; Cooper, Michael K.; Rubin, Joshua B.; Liau, Linda M.; Garami, Miklos; Hauser, Peter; Li, Kay Ka Wai; Ng, Ho-Keung; Poon, Wai Sang; Gillespie, G. Yancey; Chan, Jennifer A.; Jung, Shin; McLendon, Roger E.; Thompson, Eric M.; Zagzag, David; Vibhakar, Rajeev; Ra, Young Shin; Garre, Maria Luisa; Schueller, Ulrich; Shofuda, Tomoko; Faria, Claudia C.; Lopez-Aguilar, Enrique; Zadeh, Gelareh; Hui, Chi-Chung; Ramaswamy, Vijay; Bailey, Swneke D.; Jones, Steven J.; Mungall, Andrew J.; Moore, Richard A.; Calarco, John A.; Stein, Lincoln D.; Bader, Gary D.; Reimand, Juri; Ragoussis, Jiannis; Weiss, William A.; Marra, Marco A.; Suzuki, Hiromichi; Taylor, Michael D. Share Save PRMT5 inhibition disrupts splicing and stemness in glioblastomaSachamitr, Patty; Ho, Jolene C.; Ciamponi, Felipe E.; Ba-Alawi, Wail; Coutinho, Fiona J.; Guilhamon, Paul; Kushida, Michelle M.; Cavalli, Florence M. G.; Lee, Lilian; Rastegar, Naghmeh; Vu, Victoria; Sanchez-Osuna, Maria; Coulombe-Huntington, Jasmin; Kanshin, Evgeny; Whetstone, Heather; Durand, Mathieu; Thibault, Philippe; Hart, Kirsten; Mangos, Maria; Veyhl, Joseph; Chen, Wenjun; Tran, Nhat; Duong, Bang-Chi; Aman, Ahmed M.; Che, Xinghui; Lan, Xiaoyang; Whitley, Owen; Zaslaver, Olga; Barsyte-Lovejoy, Dalia; Richards, Laura M.; Restall, Ian; Caudy, Amy; Rost, Hannes L.; Bonday, Zahid Quyoom; Bernstein, Mark; Das, Sunit; Cusimano, Michael D.; Spears, Julian; Bader, Gary D.; Pugh, Trevor J.; Tyers, Mike; Lupien, Mathieu; Haibe-Kains, Benjamin; Luchman, H. Artee; Weiss, Samuel; Massirer, Katlin B.; Prinos, Panagiotis; Arrowsmith, Cheryl H.; Dirks, Peter B. Share Save Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survivalGuilhamon, Paul; Chesnelong, Charles; Kushida, Michelle M.; Nikolic, Ana; Singhal, Divya; MacLeod, Graham; Tonekaboni, Seyed Ali Madani; Cavalli, Florence M. G.; Arlidge, Christopher; Rajakulendran, Nishani; Rastegar, Naghmeh; Hao, Xiaoguang; Hassam, Rozina; Smith, Laura J.; Whetstone, Heather; Coutinho, Fiona J.; Nadorp, Bettina; Ellestad, Katrina, I; Luchman, H. Artee; Chan, Jennifer Ai-wen; Shoichet, Molly S.; Taylor, Michael D.; Haibe-Kains, Benjamin; Weiss, Samuel; Angers, Stephane; Gallo, Marco; Dirks, Peter B.; Lupien, Mathieu Share Save Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneityRichards, Laura M.; Whitley, Owen K. N.; MacLeod, Graham; Cavalli, Florence M. G.; Coutinho, Fiona J.; Jaramillo, Julia E.; Svergun, Nataliia; Riverin, Mazdak; Croucher, Danielle C.; Kushida, Michelle; Yu, Kenny; Guilhamon, Paul; Rastegar, Naghmeh; Ahmadi, Moloud; Bhatti, Jasmine K.; Bozek, Danielle A.; Li, Naijin; Lee, Lilian; Che, Clare; Luis, Erika; Park, Nicole I.; Xu, Zhiyu; Ketela, Troy; Moore, Richard A.; Marra, Marco A.; Spears, Julian; Cusimano, Michael D.; Das, Sunit; Bernstein, Mark; Haibe-Kains, Benjamin; Lupien, Mathieu; Luchman, H. Artee; Weiss, Samuel; Angers, Stephane; Dirks, Peter B.; Bader, Gary D.; Pugh, Trevor J. Share Save Revelation of shared transcriptional gradients in glioblastoma tumors and cultured glioma stem cellsWhitley, Owen K.; Richards, Laura M.; Cavalli, Florence; Guilhamon, Paul; Coutinho, Fiona; Kushida, Michelle; Luchman, H. Artee; Weiss, Samuel; Lupien, Mathieu; Dirks, Peter; Pugh, Trevor; Bader, Gary Share Save Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymomaDonovan, Laura K.; Delaidelli, Alberto; Joseph, Sujith K.; Bielamowicz, Kevin; Fousek, Kristen; Holgado, Borja L.; Manno, Alex; Srikanthan, Dilakshan; Gad, Ahmed Z.; Van Ommeren, Randy; Przelicki, David; Richman, Cory; Ramaswamy, Vijay; Daniels, Craig; Pallota, Jonelle G.; Douglas, Tajana; Joynt, Alyssa C. M.; Haapasalo, Joonas; Nor, Carolina; Vladoiu, Maria C.; Kuzan-Fischer, Claudia M.; Garzia, Livia; Mack, Stephen C.; Varadharajan, Srinidhi; Baker, Matthew L.; Hendrikse, Liam; Ly, Michelle; Kharas, Kaitlin; Balin, Polina; Wu, Xiaochong; Qin, Lei; Huang, Ning; Stucklin, Ana Guerreiro; Morrissy, A. Sorana; Cavalli, Florence M. G.; Luu, Betty; Suarez, Raul; De Antonellis, Pasqualino; Michealraj, Antony; Rastan, Avesta; Hegde, Meenakshi; Komosa, Martin; Sirbu, Olga; Kumar, Sachin A.; Abdullaev, Zied; Faria, Claudia C.; Yip, Stephen; Hukin, Juliette; Tabori, Uri; Hawkins, Cynthia; Aldape, Ken; Daugaard, Mads; Maris, John M.; Sorensen, Poul H.; Ahmed, Nabil; Taylor, Michael D. Share Save Stalled developmental programs at the root of pediatric brain tumorsJessa, Selin; Blanchet-Cohen, Alexis; Krug, Brian; Vladoiu, Maria; Coutelier, Marie; Faury, Damien; Poreau, Brice; De Jay, Nicolas; Hebert, Steven; Monlong, Jean; Farmer, W. Todd; Donovan, Laura K.; Hu, Yixing; McConechy, Melissa K.; Cavalli, Florence M. G.; Mikael, Leonie G.; Ellezam, Benjamin; Richer, Maxime; Allaire, Andrea; Weil, Alexander G.; Atkinson, Jeffrey; Farmer, Jean-Pierre; Dudley, Roy W. R.; Larouche, Valerie; Crevier, Louis; Albrecht, Steffen; Filbin, Mariella G.; Sartelet, Herve; Lutz, Pierre-Eric; Nagy, Corina; Turecki, Gustavo; Costantino, Santiago; Dirks, Peter B.; Murai, Keith K.; Bourque, Guillaume; Ragoussis, Jiannis; Garzia, Livia; Taylor, Michael D.; Jabado, Nada; Kleinman, Claudia L. Share Save Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma TumorigenesisHuang, Miller; Tailor, Jignesh; Zhen, Qiqi; Gillmor, Aaron H.; Miller, Matthew L.; Weishaupt, Holger; Chen, Justin; Zheng, Tina; Nash, Emily K.; McHenry, Lauren K.; An, Zhenyi; Ye, Fubaiyang; Takashima, Yasuhiro; Clarke, James; Ayetey, Harold; Cavalli, Florence Mg; Luu, Betty; Moriarity, Branden S.; Ilkhanizadeh, Shirin; Chavez, Lukas; Yu, Chunying; Kurian, Kathreena M.; Magnaldo, Thierry; Sevenet, Nicolas; Koch, Philipp; Pollard, Steven M.; Dirks, Peter; Snyder, Michael P.; Largaespada, David A.; Cho, Yoon Jae; Phillips, Joanna J.; Swartling, Fredrik J.; Morrissy, A. Sorana; Kool, Marcel; Pfister, Stefan M.; Taylor, Michael D.; Smith, Austin; Weiss, William A. Share Save 
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