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Benedict Seddon

university of london

39H-index
130Paper Count
5.8KCitation Count
Published Papers 54
Publication Date
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Contrasting roles for IKK-regulated inflammatory signalling pathways for development and maintenance of type 1 and adaptive γδ T cells
erreLife
IF0
err2026-04-01
err0
PREAI
errIslam, Farjana; Williams, Cayman; Hogan, Thea; Webb, Louise, V; Boal-Carvalho, Ines; Seddon, Benedict
errShare
errSave
A linear ontogeny accounts for the development of naive; memory; and tumor-infiltrating regulatory T cells in mice
errScience Immunology
IF16.3
err2025-06-20
err0
PREAI
errSanmoy Pathak; Thea Hogan; Sanket Rane; Yundi Huang; Claire Pearson; Charles Sinclair; Simon Barry; Larissa Carnevalli; Andrew J. Yates; Benedict Seddon
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errSave
NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells (Seot, 10.1038/s41418-024-01383-6, 2024)
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2024-12-03
err0
errOAAI
errLayzell, Scott; Barbarulo, Alessandro; van Loo, Geert; Beyaert, Rudi; Seddon, Benedict
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errSave
NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2024-09-26
err1
errOAAI
errLayzell, By Scott; Barbarulo, Alessandro; van Loo, Geert; Beyaert, Rudi; Seddon, Benedict
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errSave
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
errIMMUNITY
IF26.3
err2024-07-01
err3
errOAAI
errMannion, Jonathan; Gifford, Valentina; Bellenie, Benjamin; Fernando, Winnie; Garcia, Laura Ramos; Wilson, Rebecca; John, Sidonie Wicky; Udainiya, Savita; Patin, Emmanuel C.; Tiu, Crescens; Smith, Angel; Goicoechea, Maria; Craxton, Andrew; Vasconcelos, Nathalia Moraes de; Cheung, Kwai-Ming J.; Cundy, Nicholas J.; Pierrat, Olivier; Brennan, Alfie; Benstead-Hume, Graeme; Roumeliotis, Theodoros I.; Alexander, John; Muirhead, Gareth; Layzell, Scott; Lyu, Wenxin; Roulstone, Victoria; Baldock, Holly; Legrand, Arnaud; Gabel, Florian; Serrano-Aparicio, Natalia; Starling, Chris; Guo, Hongyan; Upton, Jason; Gyrd-Hansen, Mads; Seddon, Benedict; Roxanis, Ioannis; Harrington, Kevin; Haider, Syed; Choudhary, Jyoti S.; Haider, Swen; Tenev, Tencho; Meier, Pascal
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errSave
Quantifying cellular dynamics in mice using a novel fluorescent division reporter system
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-07-27
err2
errOAAI
errLukas, Eva; Hogan, Thea; Williams, Cayman; Seddon, Benedict; Yates, Andrew J.
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errSave
IKK promotes naive T cell survival by repressing RIPK1-dependent apoptosis and activating NF-κB
errSCIENCE SIGNALING
IF6.6
err2023-06-27
err3
errOAAI
errCarty, Fiona; Layzell, Scott; Barbarulo, Alessandro; Islam, Farjana; Webb, Louise V.; Seddon, Benedict
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errSave
Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-12-01
err8
errOAAI
errBlanchett, Sam; Dondelinger, Yves; Barbarulo, Alessandro; Bertrand, Mathieu J. M.; Seddon, Benedict
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errSave
Towards a unified model of naive T cell dynamics across the lifespan
errELIFE
IF0
err2022-06-09
err11
errOAAI
errRane, Sanket; Hogan, Thea; Lee, Edward; Seddon, Benedict; Yates, Andrew J.
errShare
errSave
obituary Don Mason (1934-2021)
errNATURE IMMUNOLOGY
IF27.6
err2021-02-26
err0
errOAAI
errSeddon, Benedict; Powrie, Fiona; Barclay, Neil
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errSave
NF-κB and Extrinsic Cell Death Pathways - Entwined Do-or-Die Decisions for T cells
errTRENDS IN IMMUNOLOGY
IF13.9
err2021-01-01
err37
errOAAI
errBlanchett, Sam; Boal-Carvalho, Ines; Layzell, Scott; Seddon, Benedict
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errSave
Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life
errCELL REPORTS
IF6.9
err2020-11-01
err13
errOAAI
errVerheijen, Melissa; Rane, Sanket; Pearson, Claire; Yates, Andrew J.; Seddon, Benedict
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errSave
Regulatory T Cells Restrain Interleukin-2-and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells
errIMMUNITY
IF26.3
err2020-01-01
err147
errOAAI
errSledzinska, Anna; de Mucha, Maria Vila; Bergerhoff, Katharina; Hotblack, Alastair; Demane, Dafne Franz; Ghorani, Ehsan; Akarca, Ayse U.; Marzolini, Maria A., V; Solomon, Isabelle; Vargas, Frederick Arce; Pule, Martin; Ono, Masahiro; Seddon, Benedict; Kassiotis, George; Ariyan, Charlotte E.; Kom, Thomas; Marafioti, Teresa; Lord, Graham M.; Stauss, Hans; Jenner, Richard G.; Peggs, Karl S.; Quezada, Sergio A.
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errSave
Flip the coin: IL-7 and IL-7R in health and disease
errNATURE IMMUNOLOGY
IF27.6
err2019-11-19
err228
errOAAI
errBarata, Joao T.; Durum, Scott K.; Seddon, Benedict
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errSave
Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory
errELIFE
IF0
err2019-11-19
err10
errOAAI
errHogan, Thea; Nowicka, Maria; Cownden, Daniel; Pearson, Claire F.; Yates, Andrew J.; Seddon, Benedict
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errSave
Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB
errIMMUNITY
IF26.3
err2019-02-01
err31
errOAAI
errWebb, Louise, V; Barbarulo, Alessandro; Huysentruyt, Jelle; Vanden Berghe, Tom; Takahashi, Nozomi; Ley, Steven; Vandenabeele, Peter; Seddon, Benedict
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errSave
The natural history of naive T cells from birth to maturity
errIMMUNOLOGICAL REVIEWS
IF8.3
err2018-08-11
err22
errOAAI
errSeddon, Benedict; Yates, Andrew J.
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errSave
IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2018-02-22
err34
errOAAI
errYang, Jie; Cornelissen, Ferry; Papazian, Natalie; Reijmers, Rogier M.; Llorian, Miriam; Cupedo, Tom; Coles, Mark; Seddon, Benedict
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errSave
Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels
errELIFE
IF0
err2017-03-10
err56
errOAAI
errGossel, Graeme; Hogan, Thea; Cownden, Daniel; Seddon, Benedict; Yates, Andrew J.
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errSave
IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection
errMUCOSAL IMMUNOLOGY
IF7.6
err2016-11-01
err189
errOAAI
errPelly, V. S.; Kannan, Y.; Coomes, S. M.; Entwistle, L. J.; Ruckerl, D.; Seddon, B.; MacDonald, A. S.; McKenzie, A.; Wilson, M. S.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
P
Peter Vandenabeele
H-index: 154 · Papers: 669
S
Shimon Sakaguchi
H-index: 129 · Papers: 831
K
Kevin J. Harrington
H-index: 115 · Papers: 1.5K
F
Fiona Powrie
H-index: 103 · Papers: 344
G
Gabrielle T. Belz
H-index: 92 · Papers: 408
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