Simone Nüssing - Publications, H-index & Citations

Back

Simone Nüssing

peter maccallum cancer center

18H-index

34Paper Count

1.6KCitation Count

Published Papers 23

Publication Date

The CD8+T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

IMMUNITY

IF26.3

2024-06-01

PREAI

Van Der Byl, Willem; Nussing, Simone; Peters, Timothy J.; Ahn, Antonio; Li, Hanjie; Ledergor, Guy; David, Eyal; Koh, Andrew S.; Wagle, Mayura V.; Deguit, Christian Deo T.; de Menezes, Maria N.; Travers, Avraham; Sampurno, Shienny; Ramsbottom, Kelly M.; Li, Rui; Kallies, Axel; Beavis, Paul A.; Jungmann, Ralf; Bastings, Maartje M. C.; Belz, Gabrielle T.; Goel, Shom; Trapani, Joseph A.; Crabtree, Gerald R.; Chang, Howard Y.; Amit, Ido; Goodnow, Chris C.; Luciani, Fabio; Parish, Ian A.

Save

Regulation of Exhausted CD8+ T cell Differentiation by IKZF Transcription Factors

CANCER RESEARCH

IF16.6

2024-04-15

PREAI

Reading, Sinead M.; Munoz, Isabelle; de Menezes, Maria N.; Saw, Nicole Y. L.; Ambani, Krutika; Ahn, Antonio; Nussing, Simone; Roth, Sara; Sampurno, Shienny; Ramsbottom, Kelly M.; Trapani, Joseph A.; Good-Jacobson, Kim L.; Johnstone, Ricky W.; Goel, Shom; Beavis, Paul A.; Parish, Ian A.

Save

Active maintenance of CD8+T cell naivety through regulation of global genome architecture

CELL REPORTS

IF6.9

2023-10-01

OAAI

Russ, Brendan E.; Barugahare, Adele; Dakle, Pushkar; Tsyganov, Kirril; Quon, Sara; Yu, Bingfei; Li, Jasmine; Lee, Jason K. C.; Olshansky, Moshe; He, Zhaohren; Harrison, Paul F.; See, Michael; Nussing, Simone; Morey, Alison E.; Udupa, Vibha A.; Bennett, Taylah J.; Kallies, Axel; Murre, Cornelis; Collas, Phillipe; Powell, David; Goldrath, Ananda W.; Turner, Stephen J.

Save

Beyond target cell death - Granzyme serine proteases in health and disease

MOLECULAR ASPECTS OF MEDICINE

IF10.3

2022-12-01

PREAI

Nussing, Simone; Sutton, Vivien R.; Trapani, Joseph A.; Parish, Ian A.

Save

SATB1 ensures appropriate transcriptional programs within naive CD8+ T cells

IMMUNOLOGY AND CELL BIOLOGY

IF3

2022-07-13

OAAI

Nussing, Simone; Miosge, Lisa A.; Lee, Kah; Olshansky, Moshe; Barugahare, Adele; Roots, Carla M.; Sontani, Yovina; Day, E. Bridie; Koutsakos, Marios; Kedzierska, Katherine; Goodnow, Christopher C.; Russ, Brendan E.; Daley, Stephen R.; Turner, Stephen J.

Save

Spatially Controlled Activation of Toll-like Receptor 9 with DNA-Based Nanomaterials

NANO LETTERS

IF9.1

2022-03-10

OAAI

Comberlato, Alice; Koga, Marianna M.; Nuessing, Simone; Parish, Ian A.; Bastings, Maartje M. C.

Save

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

NATURE COMMUNICATIONS

IF15.7

2021-05-13

OAAI

Wagle, Mayura, V; Vervoort, Stephin J.; Kelly, Madison J.; Van der Byl, Willem; Peters, Timothy J.; Martin, Ben P.; Martelotto, Luciano G.; Nuessing, Simone; Ramsbottom, Kelly M.; Torpy, James R.; Knight, Deborah; Reading, Sinead; Thia, Kevin; Miosge, Lisa A.; Howard, Debbie R.; Gloury, Renee; Gabriel, Sarah S.; Utzschneider, Daniel T.; Oliaro, Jane; Powell, Jonathan D.; Luciani, Fabio; Trapani, Joseph A.; Johnstone, Ricky W.; Kallies, Axel; Goodnow, Christopher C.; Parish, Ian A.

Save

Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients

NATURE COMMUNICATIONS

IF15.7

2021-05-11

OAAI

Nguyen, Thi H. O.; Koutsakos, Marios; van de Sandt, Carolien E.; Crawford, Jeremy Chase; Loh, Liyen; Sant, Sneha; Grzelak, Ludivine; Allen, Emma K.; Brahm, Tim; Clemens, E. Bridie; Auladell, Maria; Hensen, Luca; Wang, Zhongfang; Nussing, Simone; Jia, Xiaoxiao; Gunther, Patrick; Wheatley, Adam K.; Kent, Stephen J.; Aban, Malet; Deng, Yi-Mo; Laurie, Karen L.; Hurt, Aeron C.; Gras, Stephanie; Rossjohn, Jamie; Crowe, Jane; Xu, Jianqing; Jackson, David; Brown, Lorena E.; La Gruta, Nicole; Chen, Weisan; Doherty, Peter C.; Turner, Stephen J.; Kotsimbos, Tom C.; Thomas, Paul G.; Cheng, Allen C.; Kedzierska, Katherine

Save

Ptpn2 and KLRG1 regulate the generation and in skin

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-04-29

OAAI

Hochheiser, Katharina; Wiede, Florian; Wagner, Teagan; Freestone, David; Enders, Matthias H.; Olshansky, Moshe; Russ, Brendan; Nussing, Simone; Bawden, Emma; Braun, Asolina; Bachem, Annabell; Gressier, Elise; McConville, Robyn; Park, Simone L.; Jones, Claerwen M.; Davey, Gayle M.; Gyorki, David E.; Tscharke, David; Parish, Ian A.; Turner, Stephen; Herold, Marco J.; Tiganis, Tony; Bedoui, Sammy; Gebhardt, Thomas

Save

Revisiting T Cell Tolerance as a Checkpoint Target for Cancer Immunotherapy

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-09-23

OAAI

Nussing, Simone; Trapani, Joseph A.; Parish, Ian A.

Save

Viral burden, inflammatory milieu and CD8+T-cell responses to influenza virus in a second-generation thiazolide (RM-5061) and oseltamivir combination therapy study

INFLUENZA AND OTHER RESPIRATORY VIRUSES

IF4.2

2020-06-25

OAAI

Nuessing, Simone; Mifsud, Edin; Hensen, Luca; Koutsakos, Marios; Wang, Zhongfang; Kedzierski, Lukasz; Mercuri, Francesca; Rossignol, Jean-Francois; Hurt, Aeron C.; Kedzierska, Katherine

Save

Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies

JOURNAL OF IMMUNOLOGY

IF3.4

2020-04-15

OAAI

Nussing, Simone; House, Imran G.; Kearney, Conor J.; Chen, Amanda X. Y.; Vervoort, Stephin J.; Beavis, Paul A.; Oliaro, Jane; Johnstone, Ricky W.; Trapani, Joseph A.; Parish, Ian A.

Save

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

SCIENCE IMMUNOLOGY

IF16.3

2019-11-01

OAAI

Koay, H-F; Su, S.; Amann-Zalcenstein, D.; Daley, S. R.; Comerford, I; Miosge, L.; Whyte, C. E.; Konstantinov, I. E.; d'Udekem, Y.; Baldwin, T.; Hickey, P. F.; Berzins, S. P.; Mak, J. Y. W.; Sontani, Y.; Roots, C. M.; Sidwell, T.; Kallies, A.; Chen, Z.; Nussing, S.; Kedzierska, K.; Mackay, L. K.; McColl, S. R.; Deenick, E. K.; Fairlie, D. P.; McCluskey, J.; Goodnow, C. C.; Ritchie, M. E.; Belz, G. T.; Naik, S. H.; Pellicci, D. G.; Godfrey, D., I

Save

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction

IMMUNITY

IF26.3

2019-05-01

OAAI

Schmidleithner, Lisa; Thabet, Yasser; Schoenfeld, Eva; Koehne, Maren; Sommer, Daniel; Abdullah, Zeinab; Sadlon, Timothy; Osei-Sarpong, Collins; Subbaramaiah, Kotha; Copperi, Francesca; Haendler, Kristian; Varga, Tamas; Schanz, Oliver; Bourry, Svenja; Bassler, Kevin; Krebs, Wolfgang; Peters, Annika E.; Baumgart, Ann-Kathrin; Schneeweiss, Maria; Klee, Kathrin; Schmidt, Susanne V.; Nuessing, Simone; Sander, Jil; Ohkura, Naganari; Waha, Andreas; Sparwasser, Tim; Wunderlich, F. Thomas; Foerster, Irmgard; Ulas, Thomas; Weighardt, Heike; Sakaguchi, Shimon; Pfeifer, Alexander; Blueher, Matthias; Dannenberg, Andrew J.; Ferreiros, Nerea; Muglia, Louis J.; Wickenhauser, Claudia; Barry, Simon C.; Schultze, Joachim L.; Beyer, Marc

Save

Divergent SATB1 expression across human life span and tissue compartments

IMMUNOLOGY AND CELL BIOLOGY

IF3

2019-02-25

OAAI

Nussing, Simone; Koay, Hui-Fern; Sant, Sneha; Loudovaris, Thomas; Mannering, Stuart I.; Lappas, Martha; d'Udekem, Yves; Konstantinov, Igor E.; Berzins, Stuart P.; Rimmelzwaan, Guus F.; Turner, Stephen J.; Clemens, E. Bridie; Godfrey, Dale I.; Thi HO Nguyen; Kedzierska, Katherine

Save

Limited Phenotypic and Functional Plasticity of Influenza Virus-Specific Memory CD8+ T Cells during Activation in an Alternative Cytokine Environment

JOURNAL OF IMMUNOLOGY

IF3.4

2018-12-01

OAAI

Harland, Kim L.; Fox, Annette; Nussing, Simone; Hensen, Luca; Kedzierska, Katherine; Turner, Stephen J.; Kelso, Anne

Save

MAIT cells contribute to a protective antiviral innate response to influenza infection

EUROPEAN RESPIRATORY JOURNAL

IF21

2018-11-19

OAAI

Hinks, Timothy; van Wilgenburg, Bonnie; Loh, Liyen; Chen, Zhenjun; Pediongco, Troi; Wang, Huimeng; Shi, Mai; Zhao, Zhe; Koutsakos, Marios; Nussing, Simone; Sant, Sneha; Wang, Zhongfang; D'Souza, Criselle; Almeida, Catarina; Reading, Patrick; Corbett, Alexandra; Mccluskey, James; Klenerman, Paul; Kedzierska, Katherine

Save

MAIT CELLS CONTRIBUTE TO A PROTECTIVE ANTIVIRAL INNATE RESPONSE TO INFLUENZA INFECTION

THORAX

IF7.7

2018-11-16

PREAI

Hinks, T. S. C.; van Wilgenburg, B.; Loh, L.; Pediongco, T. J.; Wang, H.; Shi, M.; Zhao, Z.; Koutsakos, M.; Nussing, S.; Sant, S.; Wang, Z.; D'Souza, C.; Almeida, C. F.; Reading, P.; Corbett, A. J.; McCluskey, J.; Klenerman, P.; Kedzierska, K.

Save

MAIT cells contribute to protection against lethal influenza infection in vivo

NATURE COMMUNICATIONS

IF15.7

2018-11-09

163

OAAI

van Wilgenburg, Bonnie; Loh, Liyen; Chen, Zhenjun; Pediongco, Troi J.; Wang, Huimeng; Shi, Mai; Zhao, Zhe; Koutsakos, Marios; Nussing, Simone; Sant, Sneha; Wang, Zhongfang; D'Souza, Criselle; Jia, Xiaoxiao; Almeida, Catarina F.; Kostenko, Lyudmila; Eckle, Sidonia B. G.; Meehan, Bronwyn S.; Kallies, Axel; Godfrey, Dale I.; Reading, Patrick C.; Corbett, Alexandra J.; McCluskey, James; Klenerman, Paul; Kedzierska, Katherine; Hinks, Timothy S. C.

Save

Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2018-02-14

189

OAAI

Koutsakos, Marios; Wheatley, Adam K.; Loh, Liyen; Clemens, E. Bridie; Sant, Sneha; Nussing, Simone; Fox, Annette; Chung, Amy W.; Laurie, Karen L.; Hurt, Aeron C.; Rockman, Steve; Lappas, Martha; Loudovaris, Thomas; Mannering, Stuart I.; Westall, Glen P.; Elliot, Michael; Tangye, Stuart G.; Wakim, Linda M.; Kent, Stephen J.; Nguyen, Thi H. O.; Kedzierska, Katherine

Save

Research Directions