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Loss of the tumour suppressor LKB1/STK11 uncovers a leptin-mediated sensitivity mechanism to mitochondrial uncouplers for targeted cancer therapy Angelopoulou, Andriani; Theocharous, Giorgos; Valakos, Dimitrios; Polyzou, Aikaterini; Magkouta, Sophia; Myrianthopoulos, Vassilios; Havaki, Sophia; Fiorillo, Marco; Tremi, Ioanna; Vachlas, Konstantinos; Nisotakis, Theodoros; Thanos, Dimitris-Foivos; Pantazaki, Anastasia; Kletsas, Dimitris; Bartek, Jiri; Petty, Russell; Thanos, Dimitris; McCrimmon, Rory J.; Papaspyropoulos, Angelos; Gorgoulis, Vassilis G. Share Save
Endothelial progenitors exhibit a senescent and prothrombotic phenotype post COVID19 disease Paschalaki, Koralia; Gresham, Daisy; Shah, Anand; Kelleher, Peter; Reed, Anna; Singanayagam, Aran; Gorgoulis, Vassilis; Barnes, Peter J.; Randi, Anna; Pericleous, Charis; George, Peter Share Save
A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer Mourkioti, Ioanna; Polyzou, Aikaterini; Veroutis, Dimitris; Theocharous, George; Lagopati, Nefeli; Gentile, Emanuela; Stravokefalou, Vasiliki; Thanos, Dimitris-Foivos; Havaki, Sophia; Kletsas, Dimitris; Panaretakis, Theocharis; Logothetis, Christopher J.; Stellas, Dimitris; Petty, Russell; Blandino, Giovanni; Papaspyropoulos, Angelos; Gorgoulis, Vassilis G. Share Save
The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression (vol 43, pg 212, 2011) Schramek, Daniel; Kotsinas, Athanassios; Meixner, Arabella; Wada, Teiji; Elling, Ulrich; Pospisilik, J. Andrew; Neely, G. Gregory; Zwick, Ralf-Harun; Sigl, Verena; Forni, Guido; Serrano, Manuel; Gorgoulis, Vassilis G.; Penninger, Josef M. Share Save
OXC-101 shows favorable safety profile in first in human phase 1 trial in patients with advanced solid cancer Yachnin, Jeffrey; Ny, Lars; Sandvall, Teresa; Sanjiv, Kumar; Scobie, Martin; Platzack, Bjorn; Barancewski, Pawel; Breuer, Olof; Gorgoulis, Vassilis; Pateras, Ioannis S.; Klockare, Maria; Smith, Austin; Berglund, Ulrika Warpman; Helleday, Thomas Share Save
A tumor-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer Gonzalez-Gualda, Estela; Macias, David; Morsli, Samir; Martin, Jose Ezequiel; Ou, Hui-Ling; Denholm, Mary; Olan, Ioana; Hoffmann, Reuben; Dane, Mark; Veroutis, Dimitris; Medrano, Guillermo; Mulero, Francisca; Martins, Carla P.; Barbacid, Mariano; Gorgoulis, Vassilis; Korkola, James E.; Rassl, Doris M.; Doherty, Gary J.; Rintoul, Robert C.; Narita, Masashi; Munoz-Espin, Daniel Share Save
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Evaluation of senescent cells in intervertebral discs by lipofuscin staining (vol 199, 111564, 2021) Veroutis, Dimitris; Kouroumalis, Anastasios; Lagopati, Nefeli; Polyzou, Aikaterini; Chamilos, Christos; Papadodima, Stavroula; Evangelou, Konstantinos; Gorgoulis, Vassilis G. G.; Kletsas, Dimitris Share Save
Alveolar type II cells harbouring SARS-CoV-2 show senescence with a proinflammatory phenotype Paschalaki, Koralia; Evangelou, Konstantinos; Veroutis, Dimitris; Foukas, Periklis; Kittas, Christos; Tzioufas, Athanasios; De Leval, Laurence; Vassilakos, Demetris; Barnes, Peter; Gorgoulis, Vassilis Share Save
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Nanomedicine: Photo-activated nanostructured titanium dioxide, as a promising anticancer agent Lagopati, Nefeli; Evangelou, Konstantinos; Falaras, Polycarpos; Tsilibary, Effie-Photini C.; Vasileiou, Panagiotis V. S.; Havaki, Sofia; Angelopoulou, Andriani; Pavlatou, Evangelia A.; Gorgoulis, Vassilis G. Share Save
A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence (vol 19, 37, 2018) Komseli, Eirini-Stavroula; Pateras, Ioannis S.; Krejsgaard, Thorbjorn; Stawiski, Konrad; Rizou, Sophia V.; Polyzos, Alexander; Roumelioti, Fani-Marlen; Chiourea, Maria; Mourkioti, Ioanna; Paparouna, Eleni; Zampetidis, Christos P.; Gumeni, Sentiljana; Trougakos, Ioannis P.; Pefani, Dafni-Eleftheria; O'Neill, Eric; Gagos, Sarantis; Eliopoulos, Aristides G.; Fendler, Wojciech; Chowdhury, Dipanjan; Bartek, Jiri; Gorgoulis, Vassilis G. Share Save
Influence of the microenvironment on modulation of the host response by typhoid toxin Martin, Oceane C. B.; Bergonzini, Anna; Chiloeches, Maria Lopez; Paparouna, Eleni; Butter, Deborah; Theodorou, Sofia D. P.; Haykal, Maria M.; Boutet-Robinet, Elisa; Tebaldi, Toma; Wakeham, Andrew; Rhen, Mikael; Gorgoulis, Vassilis G.; Mak, Tak; Pateras, Ioannis S.; Frisan, Teresa Share Save
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