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Exploring the Impact of Saccharin on Neovascular Age-Related Macular Degeneration: A Comprehensive Study in Patients and Mice Kuenzel, Steffen E.; Pompoes, Inga-Marie; Flesch, Leonie T. M.; Frentzel, Dominik P.; Knecht, Vitus A.; Winkler, Silvia; Skosyrski, Sergej; Ruebsam, Anne; Dreher, Felix; Kociok, Norbert; Schuette, Moritz; Dubrac, Alexandre; Lange, Bodo; Yaspo, Marie-Laure; Lehrach, Hans; Strauss, Olaf; Joussen, Antonia M.; Zeitz, Oliver Share Save
Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas Grassi, Luigi; Izuogu, Osagie G.; Jorge, Natasha A. N.; Seyres, Denis; Bustamante, Mariona; Burden, Frances; Farrow, Samantha; Farahi, Neda; Martin, Fergal J.; Frankish, Adam; Mudge, Jonathan M.; Kostadima, Myrto; Petersen, Romina; Lambourne, John J.; Rowlston, Sophia; Martin-Rendon, Enca; Clarke, Laura; Downes, Kate; Estivill, Xavier; Flicek, Paul; Martens, Joost H. A.; Yaspo, Marie-Laure; Stunnenberg, Hendrik G.; Ouwehand, Willem H.; Passetti, Fabio; Turro, Ernest; Frontini, Mattia Share Save
Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes Yi, Guoqiang; Wierenga, Albertus T. J.; Petraglia, Francesca; Narang, Pankaj; Janssen-Megens, Eva M.; Mandoli, Amit; Merkel, Angelika; Berentsen, Kim; Kim, Bowon; Matarese, Filomena; Singh, Abhishek A.; Habibi, Ehsan; Prange, Koen H. M.; Mulder, Andre B.; Jansen, Joop H.; Clarke, Laura; Heath, Simon; van der Reijden, Bert A.; Flicek, Paul; Yaspo, Marie-Laure; Gut, Ivo; Bock, Christoph; Schuringa, Jan Jacob; Altucci, Lucia; Vellenga, Edo; Stunnenberg, Hendrik G.; Martens, Joost H. A. Share Save
C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation Marneth, A. E.; Prange, K. H. M.; Al Hinai, A. S. A.; Bergevoet, S. M.; Tesi, N.; Janssen-Megens, E. M.; Kim, B.; Sharifi, N.; Yaspo, M. L.; Kuster, J.; Sanders, M. A.; Stoetman, E. C. G.; Knijnenburg, J.; Arentsen-Peters, T. C. J. M.; Zwaan, C. M.; Stunnenberg, H. G.; van den Heuvel-Eibrink, M. M.; Haferlach, T.; Fornerod, M.; Jansen, J. H.; Valk, P. J. M.; van der Reijden, B. A.; Martens, J. H. A. Share Save
Preclinical analysis and characterization of abemaciclib using three-dimensional patient-derived colorectal cancer organoid cultures Boehnke, Karsten; Calsina, Bruna; Amat, Joaquin; Hermoso, Ana; Torres, Raquel; Reinhard, Christoph; Velasco, Juan A.; Iversen, Philip W.; De Dios, Alfonso; Buchanan, Sean; Beckmann, Richard P.; Schumacher, Dirk; Regenbrecht, Christian R. A.; Yaspo, Marie-Laure; Lehrach, Hans; Lallena, Maria Jose Share Save
The role of Hedgehog signaling in the regulation of human colon cancer stem cells Regan, Joseph L.; Staudte, Stephanie; Schumacher, Dirk; Keilholz, Ulrich; Haybaeck, Johannes; Lehrach, Hans; Yaspo, Marie-Laure; Henderson, David; Steffen, Andreas; Toedling, Joern; Lesche, Ralf; Schaefer, Reinhold; Regenbrecht, Christian R.; Mumberg, Dominik; Lange, Martin Share Save
Whole transcriptome analysis of patient-derived 3D in vitro and xenograft models of colon cancer identifies placental genes required for the survival of cancer stem cells Regan, Joseph L.; Staudte, Stephanie; Schumacher, Dirk; Keilholz, Ulrich; Haybaeck, Johannes; Lehrach, Hans; Yaspo, Marie-Laure; Henderson, David; Steffen, Andreas; Toedling, Joern; Lesche, Ralf; Schaefer, Reinhold; Regenbrecht, Christian R.; Mumberg, Dominik; Lange, Martin Share Save
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The direction of cross affects obesity after puberty in male but not female offspring (vol 16, 904, 2015) Kaerst, Stefan; Arends, Danny; Heise, Sebastian; Trost, Jan; Yaspo, Marie-Laure; Amstislavskiy, Vyacheslav; Risch, Thomas; Lehrach, Hans; Brockmann, Gudrun A. Share Save
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A pipeline within the OncoTrack project for generating Patient-tumor-derived 3D cell cultures (PT3DC) and their application for individualized, targeted drug sensitivity assays Schumacher, Dirk; Boehnke, Karsten; Lange, Martin; Welte, Yvonne; Davies, Cathrin; Rivera, Maria; Keil, Marlen; Keilholz, Ulrich; Haybaeck, Johannes; Angel Velasco, Juan; Yaspo, Marie-Laure; Lehrach, Hans; Henderson, David; Reinhard, Christoph; Hoffmann, Jens; Schaefer, Reinhold; Regenbrecht, Christian Share Save
Unravelling the biology of aggressive and therapy-resistant embryonal tumors with multilayered rosettes (ETMR) Kool, Marcel; Jaeger, Natalie; Sturm, Dominik; Jones, David T. W.; Hoverstadt, Volker; Buchhalter, Ivo; Johann, Pascal; Schmidt, Christin; Ryzhova, Marina; Northcott, Paul A.; Landgraf, Pablo; Remke, Marc; Taylor, Michael D.; Hasselblatt, Martin; Schueller, Ulrich; Huang, Annie; Yaspo, Marie-Laure; von Deimling, Andreas; Eils, Roland; Lichter, Peter; Korshunov, Andrey; Pfister, Stefan M. Share Save
Parallel Profiling of the Transcriptome, Cistrome, and Epigenome in the Cellular Response to Ionizing Radiation Rashi-Elkeles, Sharon; Warnatz, Hans-Joerg; Elkon, Ran; Kupershtein, Ana; Chobod, Yuliya; Paz, Arnon; Amstislavskiy, Vyacheslav; Sultan, Marc; Safer, Hershel; Nietfeld, Wilfried; Lehrach, Hans; Shamir, Ron; Yaspo, Marie-Laure; Shiloh, Yosef Share Save
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Recurrent FGFR1 hotspot mutations represent a novel therapeutic target in childhood astrocytorna Jones, David T. W.; Hutter, Barbara; Jaeger, Natalie; Korshunov, Andrey; Kool, Marcel; Lambert, Sally R.; Dong Anh Khuong Quang; Fontebasso, Adam M.; Ryzhova, Marina; Warnatz, Hans-Joerg; Zichner, Thomas; Korbel, Jan O.; Wolf, Stephan; Yaspo, Marie-Laure; Ligon, Keith L.; Kieran, Mark W.; Brors, Benedikt; Feisberg, Joerg; Reifenberger, Guido; Collins, V. Peter; Jabado, Nada; Elis, Roland; Lichter, Peter; Pfister, Stefan M. Share Save
The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle Warnatz, Hans-Joerg; Schmidt, Dominic; Manke, Thomas; Piccini, Ilaria; Sultan, Marc; Borodina, Tatiana; Balzereit, Daniela; Wruck, Wasco; Soldatov, Alexey; Vingron, Martin; Lehrach, Hans; Yaspo, Marie-Laure Share Save
Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters Warnatz, Hans-Joerg; Querfurth, Robert; Guerasimova, Anna; Cheng, Xi; Haas, Stefan A.; Hufton, Andrew L.; Manke, Thomas; Vanhecke, Dominique; Nietfeld, Wilfried; Vingron, Martin; Janitz, Michal; Lehrach, Hans; Yaspo, Marie-Laure Share Save
Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments Richard, Hugues; Schulz, Marcel H.; Sultan, Marc; Nuernberger, Asja; Schrinner, Sabine; Balzereit, Daniela; Dagand, Emilie; Rasche, Axel; Lehrach, Hans; Vingron, Martin; Haas, Stefan A.; Yaspo, Marie-Laure Share Save
Primary differentiation in the human blastocyst: Comparative molecular portraits of inner cell mass and trophectoderm cells Adjaye, J; Huntriss, J; Herwig, R; BenKahla, A; Brink, TC; Wierling, C; Hultschig, C; Groth, D; Yaspo, ML; Picton, HM; Gosden, RG; Lehrach, H Share Save
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