William R. Markesbery - Publications, H-index & Citations

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William R. Markesbery

University of Kentucky

124H-index

611Paper Count

6.3WCitation Count

Published Papers 128

Publication Date

IMAGING THE CENTENARIAN BRAIN - A COMPUTED TOMOGRAPHIC STUDY

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

IF4.5

2015-04-27

PREAI

GOLDSTEIN, SJ; WEKSTEIN, DR; KIRKPATRICK, C; LEE, C; MARKESBERY, WR

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Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression

NEUROBIOLOGY OF AGING

IF3.5

2012-06-01

OAAI

Bradley, Melissa A.; Xiong-Fister, Shuling; Markesbery, William R.; Lovell, Mark A.

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Oxidative lipid modification of nicastrin enhances amyloidogenic ?-secretase activity in Alzheimer's disease

AGING CELL

IF7.1

2012-04-09

OAAI

Gwon, A-Ryeong; Park, Jong-Sung; Arumugam, Thiruma V.; Kwon, Yong-Kook; Chan, Sic L.; Kim, Seol-Hee; Baik, Sang-Ha; Yang, Sunghee; Yun, Young-Kwang; Choi, Yuri; Kim, Saerom; Tang, Sung-Chun; Hyun, Dong-Hoon; Cheng, Aiwu; Dann, Charles E., III; Bernier, Michel; Lee, Jaewon; Markesbery, William R.; Mattson, Mark P.; Jo, Dong-Gyu

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Increased 5S rRNA Oxidation in Alzheimer's Disease

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2012-03-02

PREAI

Ding, Qunxing; Zhu, Haiyan; Zhang, Bing; Soriano, Augusto; Burns, Roxanne; Markesbery, William R.

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Understanding Dementia Prevalence Among Centenarians

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

IF3.8

2012-03-01

OAAI

Poon, Leonard W.; Woodard, John L.; Miller, L. Stephen; Green, Robert; Gearing, Marla; Davey, Adam; Arnold, Jonathan; Martin, Peter; Siegler, Ilene C.; Nahapetyan, Lusine; Kim, Young Sek; Markesbery, William

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Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks

NEUROBIOLOGY OF AGING

IF3.5

2012-01-01

OAAI

Gleichmann, Marc; Zhang, Yongqing; Wood, William H., III; Becker, Kevin G.; Mughal, Mohamed R.; Pazin, Michael J.; van Praag, Henriette; Kobilo, Tali; Zonderman, Alan B.; Troncoso, Juan C.; Markesbery, William R.; Mattson, Mark P.

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Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study

NEUROBIOLOGY OF AGING

IF3.5

2011-12-01

OAAI

Kramer, Patricia L.; Xu, Haiyan; Woltjer, Randall L.; Westaway, Shawn K.; Clark, David; Erten-Lyons, Deniz; Kaye, Jeffrey A.; Welsh-Bohmer, Kathleen A.; Troncoso, Juan C.; Markesbery, William R.; Petersen, Ronald C.; Turner, R. Scott; Kukull, Walter A.; Bennett, David A.; Galasko, Douglas; Morris, John C.; Ott, Jurg

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Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: Insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cognitive impairment and Alzheimer's disease

PROTEOMICS

IF3.9

2011-09-22

OAAI

Robinson, Rena A. S.; Joshi, Gururaj; Huang, Quanzhen; Sultana, Rukhsana; Baker, Austin S.; Cai, Jian; Pierce, William; St Clair, Daret K.; Markesbery, William R.; Butterfield, D. Allan

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Redox Proteomics Analysis of Brains from Subjects with Amnestic Mild Cognitive Impairment Compared to Brains from Subjects with Preclinical Alzheimer's Disease: Insights into Memory Loss in MCI

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2011-02-26

PREAI

Aluise, Christopher D.; Robinson, Rena A. S.; Cai, Jian; Pierce, William M.; Markesbery, William R.; Butterfield, D. Allan

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Neuron Specific Toxicity of Oligomeric Amyloid-β: Role for JUN-Kinase and Oxidative Stress

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2010-11-25

OAAI

Ebenezer, Philip J.; Weidner, Adam M.; LeVine, Harry, III; Markesbery, William R.; Murphy, M. Paul; Zhang, Le; Dasuri, Kalavathi; Fernandez-Kim, Sun Ok; Bruce-Keller, Annadora J.; Gavilan, Elena; Keller, Jeffrey N.

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Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease

NEUROBIOLOGY OF AGING

IF3.5

2010-10-01

OAAI

Jicha, G. A.; Schmitt, F. A.; Abner, E.; Nelson, P. T.; Cooper, G. E.; Smith, C. D.; Markesbery, W. R.

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Preclinical Alzheimer disease: Brain oxidative stress, Aβ peptide and proteomics

NEUROBIOLOGY OF DISEASE

IF5.6

2010-08-01

OAAI

Aluise, Christopher D.; Robinson, Rena A. Sowell; Beckett, Tina L.; Murphy, M. Paul; Cai, Jian; Pierce, William M.; Markesbery, William R.; Butterfield, D. Allan

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Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2010-06-15

176

OAAI

Bradley, M. A.; Markesbery, W. R.; Lovell, M. A.

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NOX Activity Is Increased in Mild Cognitive Impairment

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2010-06-15

OAAI

Bruce-Keller, Annadora J.; Gupta, Sunita; Parrino, Taryn E.; Knight, Alecia G.; Ebenezer, Philip J.; Weidner, Adam M.; LeVine, Harry, III; Keller, Jeffrey N.; Markesbery, William R.

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Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease

NEUROBIOLOGY OF AGING

IF3.5

2010-06-01

OAAI

Jo, Dong-Gyu; Arumugam, Thiruma V.; Woo, Ha-Na; Park, Jong-Sung; Tang, Sung-Chun; Mughal, Mohamed; Hyun, Dong-Hoon; Park, Jun-Hyung; Choi, Yun-Hyung; Gwon, A-Ryeong; Camandola, Simonetta; Cheng, Aiwu; Cai, Huaibin; Song, Weihong; Markesbery, William R.; Mattson, Mark P.

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Increased protein hydrophobicity in response to aging and Alzheimer disease

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2010-05-15

OAAI

Dasuri, Kalavathi; Ebenezer, Philip; Zhang, Le; Fernandez-Kim, Sun Ok; Bruce-Keller, Annadora J.; Markesbery, William R.; Keller, Jeffrey N.

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NEUROBIOLOGY OF DISEASE

IF5.6

2010-04-01

OAAI

Lange, Miranda L. Bader; Clair, Daret St.; Markesbery, William R.; Studzinski, Christa M.; Murphy, M. Paul; Butterfield, D. Allan

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Alterations of Zinc Transporter Proteins ZnT-1, ZnT-4 and ZnT-6 in Preclinical Alzheimer's Disease Brain

BRAIN PATHOLOGY

IF6.2

2010-02-02

OAAI

Lyubartseva, Ganna; Smith, Jennifer L.; Markesbery, William R.; Lovell, Mark A.

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Quantitative Changes in the Mitochondrial Proteome from Subjects with Mild Cognitive Impairment, Early Stage, and Late Stage Alzheimer's Disease

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2010-01-06

OAAI

Lynn, Bert C.; Wang, Jianquan; Markesbery, William R.; Lovell, Mark A.

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Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons

BRAIN PATHOLOGY

IF6.2

2009-12-07

193

OAAI

Nelson, Peter T.; Abner, Erin L.; Schmitt, Frederick A.; Kryscio, Richard J.; Jicha, Gregory A.; Smith, Charles D.; Davis, Daron G.; Poduska, John W.; Patel, Ela; Mendiondo, Marta S.; Markesbery, William R.

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Research Directions