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Transcriptome analysis of archived tumors by Visium, GeoMx DSP, and Chromium reveals patient heterogeneity Dong, Yixing; Saglietti, Chiara; Bayard, Quentin; Perez, Almudena Espin; Carpentier, Sabrina; Buszta, Daria; Tissot, Stephanie; Dubois, Remy; Kamburov, Atanas; Kang, Senbai; Haignere, Carla; Sarkis, Rita; Andre, Sylvie; Gaveta, Marina Alexandre; Lastra, Silvia Lopez; Piazzon, Nathalie; Santos, Rita; von Loga, Katharina; Hoffmann, Caroline; Coukos, George; Peters, Solange; Soumelis, Vassili; Durand, Eric Yves; Homicsko, Krisztian; Madissoon, Elo Share Save
Deep learning tertiary lymphoid structures detection on HES/H&E slides and association to survival outcome in sarcoma Vanhersecke, L.; Rodriguez, Y.; Jacob, P.; Gillet, L.; Le Douget, J-E.; Coindre, J. M.; MacGrogan, G.; von Loga, K.; Schutte, K.; Italiano, A. Share Save
Maintenance durvalumab after fi rst-line chemotherapy in patients with HER2-negative advanced oesophago-gastric adenocarcinoma: results from the randomised PLATFORM study Fong, C.; Patel, B.; Peckitt, C.; Bourmpaki, E.; Satchwell, L.; Cromarty, S.; Kidd, S.; von Loga, K.; Uhlik, M.; Begum, R.; Rana, T.; Waddell, T.; Darby, S.; Bradshaw, A.; Roques, T.; Morgan, C.; Rees, C.; Herbertson, R.; Das, P.; Thompson, C.; Hewish, M.; Petty, R.; Thistlethwaite, F.; Rao, S.; Starling, N.; Chau, I.; Cunningham, D. Share Save
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Deep learning uncovers morphological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients Schmauch, Benoit; Cabeli, Vincent; Darwiche-Domingues, Omar; Le Douget, Jean-Eudes; Hardy, Alexandra; Belbahri, Reda; Maussion, Charles; Romagnoni, Alberto; Eckstein, Markus; Fuchs, Florian; Swalduz, Aurelie; Lantuejoul, Sylvie; Crochet, Hugo; Ghiringhelli, Francois; Derangere, Valentin; Truntzer, Caroline; Pass, Harvey; Moreira, Andre; Chiriboga, Luis; Zheng, Yuanning; Ozawa, Michael; Howitt, Brooke; Gevaert, Olivier; Girard, Nicolas; Rexhepaj, Elton; Valtingojer, Iris; Debussche, Laurent; Durand, Eric; Classe, Marion; Von Loga, Katharina; Pronier, Elodie; Cesaroni, Matteo Share Save
Genetic and immune landscape evolution in MMR-deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Fong, Caroline; Barber, Louise J.; Anandappa, Gayathri; Crux, Richard; Assiotis, Ioannis; Fenwick, Kerry; Begum, Ruwaida; Begum, Dipa; Lund, Tom; Sivamanoharan, Nanna; Sansano, Harold B.; Domingo-Arada, Melissa; Tran, Amina; Pandha, Hardev; Church, David; Eccles, Bryony; Ellis, Richard; Falk, Stephen; Hill, Mark; Krell, Daniel; Murugaesu, Nirupa; Nolan, Luke; Potter, Vanessa; Saunders, Mark; Shiu, Kai-Keen; Guettler, Sebastian; Alexander, James L.; Lazare-Iglesias, Hector; Kinross, James; Murphy, Jamie; von Loga, Katharina; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides Saillard, Charlie; Dubois, Remy; Tchita, Oussama; Loiseau, Nicolas; Garcia, Thierry; Adriansen, Aurelie; Carpentier, Severine; Reyre, Joelle; Enea, Diana; von Loga, Katharina; Kamoun, Aurelie; Rossat, Stephane; Wiscart, Corentin; Sefta, Meriem; Auffret, Michael; Guillou, Lionel; Fouillet, Arnaud; Kather, Jakob Nikolas; Svrcek, Magali Share Save
Pathological regression of primary tumour and metastatic lymph nodes following chemotherapy in resectable OG cancer: pooled analysis of two trials Athauda, Avani; Nankivell, Matthew; Langer, Rupert; Pritchard, Susan; Langley, Ruth E.; von Loga, Katharina; Starling, Naureen; Chau, Ian; Cunningham, David; Grabsch, Heike I. Share Save
Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Barber, Louise J.; Lund, Tom; Sansano, Harold B.; von Loga, Katharina; Lazare-Iglesias, Hector; Begum, Ruwaida; Crux, Richard; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Barber, Louise J.; Lund, Tom; Sansano, Harold B.; von Loga, Katharina; Lazare-Iglesias, Hector; Begum, Ruwaida; Crux, Richard; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer Wilkins, Anna; Fontana, Elisa; Nyamundanda, Gift; Ragulan, Chanthirika; Patil, Yatish; Mansfield, David; Kingston, Jennifer; Errington-Mais, Fiona; Bottomley, Daniel; von Loga, Katharina; Bye, Hannah; Carter, Paul; Tinkler-Hundal, Emma; Noshirwani, Amir; Downs, Jessica; Dillon, Magnus; Demaria, Sandra; Sebag-Montefiore, David; Harrington, Kevin; West, Nick; Melcher, Alan; Sadanandam, Anguraj Share Save
The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation Taube, Janis M.; Akturk, Guray; Angelo, Michael; Engle, Elizabeth L.; Gnjatic, Sacha; Greenbaum, Shirley; Greenwald, Noah F.; Hedvat, Cyrus, V; Hollmann, Travis J.; Juco, Jonathan; Parra, Edwin R.; Rebelatto, Marlon C.; Rimm, David L.; Rodriguez-Canales, Jaime; Schalper, Kurt A.; Stack, Edward C.; Ferreira, Claudia S.; Korski, Konstanty; Lako, Ana; Rodig, Scott J.; Schenck, Emanuel; Steele, Keith E.; Surace, Michael J.; Tetzlaff, Michael T.; von Loga, Katharina; Wistuba, Ignacio I.; Bifulco, Carlo B. Share Save
Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes Challoner, Benjamin R.; von Loga, Katharina; Woolston, Andrew; Griffiths, Beatrice; Sivamanoharan, Nanna; Semiannikova, Maria; Newey, Alice; Barber, Louise J.; Mansfield, David; Hewitt, Lindsay C.; Saito, Yuichi; Davarzani, Naser; Starling, Naureen; Melcher, Alan; Grabsch, Heike, I; Gerlinger, Marco Share Save
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer (vol 11, 139, 2020) von Loga, Katharina; Woolston, Andrew; Punta, Marco; Barber, Louise J.; Griffiths, Beatrice; Semiannikova, Maria; Spain, Georgia; Challoner, Benjamin; Fenwick, Kerry; Simon, Ronald; Marx, Andreas; Sauter, Guido; Lise, Stefano; Matthews, Nik; Gerlinger, Marco Share Save
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer von Loga, Katharina; Woolston, Andrew; Punta, Marco; Barber, Louise J.; Griffiths, Beatrice; Semiannikova, Maria; Spain, Georgia; Challoner, Benjamin; Fenwick, Kerry; Simon, Ronald; Marx, Andreas; Sauter, Guido; Lise, Stefano; Matthews, Nik; Gerlinger, Marco Share Save
MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer Khakoo, Shelize; Carter, Paul David; Brown, Gina; Valeri, Nicola; Picchia, Simona; Bali, Maria Antonietta; Shaikh, Ridwan; Jones, Thomas; Begum, Ruwaida; Rana, Isma; Wotherspoon, Andrew; Terlizzo, Monica; von Loga, Katharina; Kalaitzaki, Eleftheria; Saffery, Claire; Watkins, David; Tait, Diana; Chau, Ian; Starling, Naureen; Hubank, Michael; Cunningham, David Share Save
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids Gonzalez-Exposito, Reyes; Semiannikova, Maria; Griffiths, Beatrice; Khan, Khurum; Barber, Louise J.; Woolston, Andrew; Spain, Georgia; von Loga, Katharina; Challoner, Ben; Patel, Radhika; Ranes, Michael; Swain, Amanda; Thomas, Janet; Bryant, Annette; Saffery, Claire; Fotiadis, Nicos; Guettler, Sebastian; Mansfield, David; Melcher, Alan; Powles, Thomas; Rao, Sheela; Watkins, David; Chau, Ian; Matthews, Nik; Wallberg, Fredrik; Starling, Naureen; Cunningham, David; Gerlinger, Marco Share Save
Ultra-Sensitive Mutation Detection and Genome-Wide DNA Copy Number Reconstruction by Error-Corrected Circulating Tumor DNA Sequencing Mansukhani, Sonia; Barber, Louise J.; Kleftogiannis, Dimitrios; Moorcraft, Sing Yu; Davidson, Michael; Woolston, Andrew; Proszek, Paula Zuzanna; Griffiths, Beatrice; Fenwick, Kerry; Herman, Bram; Matthews, Nik; O'Leary, Ben; Hulkki, Sanna; De Castro, David Gonzalez; Patel, Anisha; Wotherspoon, Andrew; Okachi, Aleruchi; Rana, Isma; Begum, Ruwaida; Davies, Matthew N.; Powles, Thomas; von Loga, Katharina; Hubank, Michael; Turner, Nick; Watkins, David; Chau, Ian; Cunningham, David; Lise, Stefano; Starling, Naureen; Gerlinger, Marco Share Save
Molecular subtypes and novel genetic mechanisms of primary and acquired anti-EGFR resistance in colorectal cancer in the Prospect C biomarker trial Khan, Khurum Hayat; Woolston, Andrew; Spain, Georgia; Barber, Louise; Patil, Yatish; Griffiths, Beatrice; GonzalezExposito, Reyes; Mansukhani, Sonia; Davies, Matthew; Rao, Sheela; Watkins, David; Sclafani, Francesco; Suntharanathan, Jana; Peckitt, Clare; Begum, Ruwaida; Rana, Isma; Thomas, Janet; Oates, Jacqui; Bryant, Annette; Wotherspoon, Andrew; Fotiadis, Nicos; Khan, Nasir; Guettler, Sebastian; von Loga, Katharina; Starling, Naureen; Chau, Ian; Sadanandam, Anguraj; Cunningham, David; Gerlinger, Marco Share Save
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