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Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample Petty, Lauren E.; Highland, Heather M.; Gamazon, Eric R.; Hu, Hao; Karhade, Mandar; Chen, Hung-Hsin; de Vries, Paul S.; Grove, Megan L.; Aguilar, David; Bell, Graeme I.; Huff, Chad D.; Hanis, Craig L.; Doddapaneni, HarshaVardhan; Munzy, Donna M.; Gibbs, Richard A.; Ma, Jianzhong; Parra, Esteban J.; Cruz, Miguel; Valladares-Salgado, Adan; Arking, Dan E.; Barbeira, Alvaro; Im, Hae Kyung; Morrison, Alanna C.; Boerwinkle, Eric; Below, Jennifer E. Share Save
Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men Chen, Han; Cade, Brian E.; Gleason, Kevin J.; Bjonnes, Andrew C.; Stilp, Adrienne M.; Sofer, Tamar; Conomos, Matthew P.; Ancoli-Israel, Sonia; Arens, Raanan; Azarbarzin, Ali; Bell, Graeme I.; Below, Jennifer E.; Chun, Sung; Evans, Daniel S.; Ewert, Ralf; Frazier-Wood, Alexis C.; Gharib, Sina A.; Haba-Rubio, Jose; Hagen, Erika W.; Heinzer, Raphael; Hillman, David R.; Johnson, W. Craig; Kutalik, Zoltan; Lane, Jacqueline M.; Larkin, Emma K.; Lee, Seung Ku; Liang, Jingjing; Loredo, Jose S.; Mukherjee, Sutapa; Palmer, Lyle J.; Papanicolaou, George J.; Penzel, Thomas; Peppard, Paul E.; Post, Wendy S.; Ramos, Alberto R.; Rice, Ken; Rotter, Jerome I.; Sands, Scott A.; Shah, Neomi A.; Shin, Chol; Stone, Katie L.; Stubbe, Beate; Sul, Jae Hoon; Tafti, Mehdi; Taylor, Kent D.; Teumer, Alexander; Thornton, Timothy A.; Tranah, Gregory J.; Wang, Chaolong; Wang, Heming; Warby, Simon C.; Wellman, D. Andrew; Zee, Phyllis C.; Hanis, Craig L.; Laurie, Cathy C.; Gottlieb, Daniel J.; Patel, Sanjay R.; Zhu, Xiaofeng; Sunyaev, Shamil R.; Saxena, Richa; Lin, Xihong; Redline, Susan Share Save
Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees Jun, Goo; Manning, Alisa; Almeida, Marcio; Zawistowski, Matthew; Wood, Andrew R.; Teslovich, Tanya M.; Fuchsberger, Christian; Feng, Shuang; Cingolani, Pablo; Gaulton, Kyle J.; Dyer, Thomas; Blackwell, Thomas W.; Chen, Han; Chines, Peter S.; Choi, Sungkyoung; Churchhouse, Claire; Fontanillas, Pierre; King, Ryan; Lee, SungYoung; Lincoln, Stephen E.; Trubetskoy, Vasily; DePristo, Mark; Fingerlin, Tasha; Grossman, Robert; Grundstad, Jason; Heath, Alison; Kim, Jayoun; Kim, Young Jin; Laramie, Jason; Lee, Jaehoon; Li, Heng; Liu, Xuanyao; Livne, Oren; Locke, Adam E.; Maller, Julian; Mazur, Alexander; Morris, Andrew P.; Pollin, Toni I.; Ragona, Derek; Reich, David; Rivas, Manuel A.; Scott, Laura J.; Sim, Xueling; Tearle, Rick G.; Teo, Yik Ying; Williams, Amy L.; Zollner, Sebastian; Curran, Joanne E.; Peralta, Juan; Akolkar, Beena; Bell, Graeme I.; Burtt, Noel P.; Cox, Nancy J.; Florez, Jose C.; Hanis, Craig L.; McKeon, Catherine; Mohlke, Karen L.; Seielstad, Mark; Wilson, James G.; Atzmon, Gil; Below, Jennifer E.; Dupuis, Josee; Nicolae, Dan L.; Lehman, Donna; Park, Taesung; Won, Sungho; Sladek, Robert; Altshuler, David; McCarthy, Mark I.; Duggirala, Ravindranath; Boehnke, Michael; Frayling, Timothy M.; Abecasis, Goncalo R.; Blangero, John Share Save
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk Manning, Alisa; Highland, Heather M.; Gasser, Jessica; Sim, Xueling; Tukiainen, Taru; Fontanillas, Pierre; Grarup, Niels; Rivas, Manuel A.; Mahajan, Anubha; Locke, Adam E.; Cingolani, Pablo; Pers, Tune H.; Vinuela, Ana; Brown, Andrew A.; Wu, Ying; Flannick, Jason; Fuchsberger, Christian; Gamazon, Eric R.; Gaulton, Kyle J.; Im, Hae Kyung; Teslovich, Tanya M.; Blackwell, Thomas W.; Bork-Jensen, Jette; Burtt, Noel P.; Chen, Yuhui; Green, Todd; Hartl, Christopher; Kang, Hyun Min; Kumar, Ashish; Ladenvall, Claes; Ma, Clement; Moutsianas, Loukas; Pearson, Richard D.; Perry, John R. B.; Rayner, N. William; Robertson, Neil R.; Scott, Laura J.; van de Bunt, Martijn; Eriksson, Johan G.; Jula, Antti; Koskinen, Seppo; Lehtimaki, Terho; Palotie, Aarno; Raitakari, Olli T.; Jacobs, Suzanne B. R.; Wessel, Jennifer; Chu, Audrey Y.; Scott, Robert A.; Goodarzi, Mark O.; Blancher, Christine; Buck, Gemma; Buck, David; Chines, Peter S.; Gabriel, Stacey; Gjesing, Anette P.; Groves, Christopher J.; Hollensted, Mette; Huyghe, Jeroen R.; Jackson, Anne U.; Jun, Goo; Justesen, Johanne Marie; Mangino, Massimo; Murphy, Jacquelyn; Neville, Matt; Onofrio, Robert; Small, Kerrin S.; Stringham, Heather M.; Trakalo, Joseph; Banks, Eric; Carey, Jason; Carneiro, Mauricio O.; DePristo, Mark; Farjoun, Yossi; Fennell, Timothy; Goldstein, Jacqueline I.; Grant, George; de Angelis, Martin Hrabe; Maguire, Jared; Neale, Benjamin M.; Poplin, Ryan; Purcell, Shaun; Schwarzmayr, Thomas; Shakir, Khalid; Smith, Joshua D.; Strom, Tim M.; Wieland, Thomas; Lindstrom, Jaana; Brandslund, Ivan; Christensen, Cramer; Surdulescu, Gabriela L.; Lakka, Timo A.; Doney, Alex S. F.; Nilsson, Peter; Wareham, Nicholas J.; Langenberg, Claudia; Varga, Tibor V.; Franks, Paul W.; Rolandsson, Olov; Rosengren, Anders H.; Farook, Vidya S.; Thameem, Farook; Puppala, Sobha; Kumar, Satish; Lehman, Donna M.; Jenkinson, Christopher P.; Curran, Joanne E.; Hale, Daniel Esten; Fowler, Sharon P.; Arya, Rector; DeFronzo, Ralph A.; Abboud, Hanna E.; Syvanen, Ann-Christine; Hicks, Pamela J.; Palmer, Nicholette D.; Ng, Maggie C. Y.; Bowden, Donald W.; Freedman, Barry I.; Esko, Tonu; Magi, Reedik; Milani, Lili; Mihailov, Evelin; Metspalu, Andres; Narisu, Narisu; Kinnunen, Leena; Bonnycastle, Lori L.; Swift, Amy; Pasko, Dorota; Wood, Andrew R.; Fadista, Joao; Pollin, Toni I.; Barzilai, Nir; Atzmon, Gil; Glaser, Benjamin; Thorand, Barbara; Strauch, Konstantin; Peters, Annette; Roden, Michael; Mueller-Nurasyid, Martina; Liang, Liming; Kriebel, Jennifer; Illig, Thomas; Grallert, Harald; Gieger, Christian; Meisinger, Christa; Lannfelt, Lars; Musani, Solomon K.; Griswold, Michael; Taylor, Herman A., Jr.; Wilson, Gregory, Sr.; Correa, Adolfo; Oksa, Heikki; Scott, William R.; Afzal, Uzma; Tan, Sian-Tsung; Loh, Marie; Chambers, John C.; Sehmi, Jobanpreet; Kooner, Jaspal Singh; Lehne, Benjamin; Cho, Yoon Shin; Lee, Jong-Young; Han, Bok-Ghee; Karajamaki, Annemari; Qi, Qibin; Qi, Lu; Huang, Jinyan; Hu, Frank B.; Melander, Olle; Orho-Melander, Marju; Below, Jennifer E.; Aguilar, David; Wong, Tien Yin; Liu, Jianjun; Khor, Chiea-Chuen; Chia, Kee Seng; Lim, Wei Yen; Cheng, Ching-Yu; Chan, Edmund; Tai, E. Shyong; Aung, Tin; Linneberg, Allan; Isomaa, Bo; Meitinger, Thomas; Tuomi, Tiinamaija; Hakaste, Liisa; Kravic, Jasmina; Jorgensen, Marit E.; Lauritzen, Torsten; Deloukas, Panos; Stirrups, Kathleen E.; Owen, Katharine R.; Farmer, Andrew J.; Frayling, Timothy M.; O'Rahilly, Stephen P.; Walker, Mark; Levy, Jonathan C.; Hodgkiss, Dylan; Hattersley, Andrew T.; Kuulasmaa, Teemu; Stancakova, Alena; Barroso, Ines; Bharadwaj, Dwaipayan; Chan, Juliana; Chandak, Giriraj R.; Daly, Mark J.; Donnelly, Peter J.; Ebrahim, Shah B.; Elliott, Paul; Fingerlin, Tasha; Froguel, Philippe; Hu, Cheng; Jia, Weiping; Ma, Ronald C. W.; McVean, Gilean; Park, Taesung; Prabhakaran, Dorairaj; Sandhu, Manjinder; Scott, James; Sladek, Rob; Tandon, Nikhil; Teo, Yik Ying; Zeggini, Eleftheria; Watanabe, Richard M.; Koistinen, Heikki A.; Kesaniemi, Y. Antero; Uusitupa, Matti; Spector, Timothy D.; Salomaa, Veikko; Rauramaa, Rainer; Palmer, Colin N. A.; Prokopenko, Inga; Morris, Andrew D.; Bergman, Richard N.; Collins, Francis S.; Lind, Lars; Ingelsson, Erik; Tuomilehto, Jaakko; Karpe, Fredrik; Groop, Leif; Jorgensen, Torben; Hansen, Torben; Pedersen, Oluf; Kuusisto, Johanna; Abecasis, GonOalo; Bell, Graeme I.; Blangero, John; Cox, Nancy J.; Duggirala, Ravindranath; Seielstad, Mark; Wilson, James G.; Dupuis, Josee; Ripatti, Samuli; Hanis, Craig L.; Florez, Jose C.; Mohlke, Karen L.; Meigs, James B.; Laakso, Markku; Morris, Andrew P.; Boehnke, Michael; Altshuler, David; McCarthy, Mark I.; Gloyn, Anna L.; Lindgren, Cecilia M. Share Save
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Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans Cade, Brian E.; Chen, Han; Stilp, Adrienne M.; Gleason, Kevin J.; Sofer, Tamar; Ancoli-Israel, Sonia; Arens, Raanan; Bell, Graeme I.; Below, Jennifer E.; Bjonnes, Andrew C.; Chun, Sung; Conomos, Matthew P.; Evans, Daniel S.; Johnson, W. Craig; Frazier-Wood, Alexis C.; Lane, Jacqueline M.; Larkin, Emma K.; Loredo, Jose S.; Post, Wendy S.; Ramos, Alberto R.; Rice, Ken; Rotter, Jerome I.; Shah, Neomi A.; Stone, Katie L.; Taylor, Kent D.; Thornton, Timothy A.; Tranah, Gregory J.; Wang, Chaolong; Zee, Phyllis C.; Hanis, Craig L.; Sunyaev, Shamil R.; Patel, Sanjay R.; Laurie, Cathy C.; Zhu, Xiaofeng; Saxena, Richa; Lin, Xihong; Redline, Susan Share Save
Beyond type 2 diabetes, obesity and hypertension: an axis including sleep apnea, left ventricular hypertrophy, endothelial dysfunction, and aortic stiffness among Mexican Americans in Starr County, Texas Hanis, Craig L.; Redline, Susan; Cade, Brian E.; Bell, Graeme I.; Cox, Nancy J.; Below, Jennifer E.; Brown, Eric L.; Aguilar, David Share Save
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms Horikoshi, Momoko; Pasquali, Lorenzo; Wiltshire, Steven; Huyghe, Jeroen R.; Mahajan, Anubha; Asimit, Jennifer L.; Ferreira, Teresa; Locke, Adam E.; Robertson, Neil R.; Wang, Xu; Sim, Xueling; Fujita, Hayato; Hara, Kazuo; Young, Robin; Zhang, Weihua; Choi, Sungkyoung; Chen, Han; Kaur, Ismeet; Takeuchi, Fumihiko; Fontanillas, Pierre; Thuillier, Dorothee; Yengo, Loic; Below, Jennifer E.; Tam, Claudia H. T.; Wu, Ying; Abecasis, Goncalo; Altshuler, David; Bell, Graeme I.; Blangero, John; Burtt, Noel P.; Duggirala, Ravindranath; Florez, Jose C.; Hanis, Craig L.; Seielstad, Mark; Atzmon, Gil; Chan, Juliana C. N.; Ma, Ronald C. W.; Froguel, Philippe; Wilson, James G.; Bharadwaj, Dwaipayan; Dupuis, Josee; Meigs, James B.; Cho, Yoon Shin; Park, Taesung; Kooner, Jaspal S.; Chambers, John C.; Saleheen, Danish; Kadowaki, Takashi; Tai, E. Shyong; Mohlke, Karen L.; Cox, Nancy J.; Ferrer, Jorge; Zeggini, Eleftheria; Kato, Norihiro; Teo, Yik Ying; Boehnke, Michael; McCarthy, Mark I.; Morris, Andrew P. Share Save
Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism Carmody, David; Park, Soo-Young; Ye, Honggang; Perrone, Marie E.; Alkorta-Aranburu, G.; Highland, Heather M.; Hanis, Craig L.; Philipson, Louis H.; Bell, Graeme I.; Greeley, Siri Atma W. Share Save
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus Mahajan, Anubha; Sim, Xueling; Ng, Hui Jin; Manning, Alisa; Rivas, Manuel A.; Highland, Heather M.; Locke, Adam E.; Grarup, Niels; Im, Hae Kyung; Cingolani, Pablo; Flannick, Jason; Fontanillas, Pierre; Fuchsberger, Christian; Gaulton, Kyle J.; Teslovich, Tanya M.; Rayner, N. William; Robertson, Neil R.; Beer, Nicola L.; Rundle, Jana K.; Bork-Jensen, Jette; Ladenvall, Claes; Blancher, Christine; Buck, David; Buck, Gemma; Burtt, Noel P.; Gabriel, Stacey; Gjesing, Anette P.; Groves, Christopher J.; Hollensted, Mette; Huyghe, Jeroen R.; Jackson, Anne U.; Jun, Goo; Justesen, Johanne Marie; Mangino, Massimo; Murphy, Jacquelyn; Neville, Matt; Onofrio, Robert; Small, Kerrin S.; Stringham, Heather M.; Syvanen, Ann-Christine; Trakalo, Joseph; Abecasis, Goncalo; Bell, Graeme I.; Blangero, John; Cox, Nancy J.; Duggirala, Ravindranath; Hanis, Craig L.; Seielstad, Mark; Wilson, James G.; Christensen, Cramer; Brandslund, Ivan; Rauramaa, Rainer; Surdulescu, Gabriela L.; Doney, Alex S. F.; Lannfelt, Lars; Linneberg, Allan; Isomaa, Bo; Tuomi, Tiinamaija; Jorgensen, Marit E.; Jorgensen, Torben; Kuusisto, Johanna; Uusitupa, Matti; Salomaa, Veikko; Spector, Timothy D.; Morris, Andrew D.; Palmer, Colin N. A.; Collins, Francis S.; Mohlke, Karen L.; Bergman, Richard N.; Ingelsson, Erik; Lind, Lars; Tuomilehto, Jaakko; Hansen, Torben; Watanabe, Richard M.; Prokopenko, Inga; Dupuis, Josee; Karpe, Fredrik; Groop, Leif; Laakso, Markku; Pedersen, Oluf; Florez, Jose C.; Morris, Andrew P.; Altshuler, David; Meigs, James B.; Boehnke, Michael; McCarthy, Mark I.; Lindgren, Cecilia M.; Gloyn, Anna L. Share Save
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Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice Bailey, Kathleen A.; Savic, Daniel; Zielinski, Mark; Park, Soo-Young; Wang, Ling-jia; Witkowski, Piotr; Brady, Matthew; Hara, Manami; Bell, Graeme I.; Nobrega, Marcelo A. Share Save
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Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population Estrada, Karol; Aukrust, Ingvild; Bjorkhaug, Lise; Burtt, Noel P.; Mercader, Josep M.; Garcia-Ortiz, Humberto; Huerta-Chagoya, Alicia; Moreno-Macias, Hortensia; Walford, Geoffrey; Flannick, Jason; Williams, Amy L.; Gomez-Vazquez, Maria J.; Fernandez-Lopez, Juan C.; Martinez-Hernandez, Angelica; Centeno-Cruz, Federico; Mendoza-Caamal, Elvia; Revilla-Monsalve, Cristina; Islas-Andrade, Sergio; Cordova, Emilio J.; Soberon, Xavier; Gonzalez-Villalpando, Maria E.; Henderson, E.; Wilkens, Lynne R.; Le Marchand, Loic; Arellano-Campos, Olimpia; Ordonez-Sanchez, Maria L.; Rodriguez-Torres, Maribel; Rodriguez-Guillen, Rosario; Riba, Laura; Najmi, Laeya A.; Jacobs, Suzanne B. R.; Fennell, Timothy; Gabriel, Stacey; Fontanillas, Pierre; Hanis, Craig L.; Lehman, Donna M.; Jenkinson, Christopher P.; Abboud, Hanna E.; Bell, Graeme I.; Cortes, Maria L.; Boehnke, Michael; Gonzalez-Villalpando, Clicerio; Orozco, Lorena; Haiman, Christopher A.; Tusie-Luna, Teresa; Aguilar-Salinas, Carlos A.; Altshuler, David; Njolstad, Pal R.; Florez, Jose C.; MacArthur, Daniel G. Share Save
Genetic Complexity in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin Park, Soo-Young; Ludwig, Michael Z.; Tamarina, Natalia A.; He, Bin Z.; Carl, Sarah H.; Dickerson, Desiree A.; Barse, Levi; Arun, Bharath; Williams, Calvin L.; Miles, Cecelia M.; Philipson, Louis H.; Steiner, Donald F.; Bell, Graeme I.; Kreitman, Martin Share Save
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Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder Shalev, Stavit A.; Tenenbaum-Rakover, Yardena; Horovitz, Yoseph; Paz, Veronica P.; Ye, Honggang; Carmody, David; Highland, Heather M.; Boerwinkle, Eric; Hanis, Craig L.; Muzny, Donna M.; Gibbs, Richard A.; Bell, Graeme I.; Philipson, Louis H.; Greeley, Siri Atma W. Share Save
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