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Brian A. Hemmings

Friedrich Miescher Institute for Biomedical Research

111H-index
557Paper Count
5.1WCitation Count
Published Papers 137
Publication Date
Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions
err2023-03-27
err78
errOAAI
errTaniyama, Y; Weber, DS; Rocic, P; Hilenski, L; Akers, ML; Park, J; Hemmings, BA; Alexander, RW; Griendling, KK
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Only Akt1 is required for proliferation, while Akt2 promotes cell cycle exit through p21 binding
err2023-03-27
err182
errOAAI
errHeron-Milhavet, Lisa; Franckhauser, Celine; Rana, Vanessa; Berthenet, Cyril; Fisher, Daniel; Hemmings, Brian A.; Fernandez, Anne; Lamb, Ned J. C.
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Life with a single isoform of Akt: Mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies
err2023-03-27
err297
errOAAI
errDummler, Bettina; Tschopp, Oliver; Hynx, Debby; Yang, Zhong-Zhou; Dirnhofer, Stephan; Hemmings, Brian A.
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Apoptosis suppression by Raf-1 and MEK1 requires MEK-and phosphatidylinositol 3-kinase-dependent signals
err2023-03-27
err175
errOAAI
errvon Gise, A; Lorenz, P; Wellbrock, C; Hemmings, B; Berberich-Siebelt, F; Rapp, UR; Troppmair, J
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Alternative splicing controls myotonic dystrophy protein kinase structure, enzymatic activity, and subcellular localization
err2023-03-27
err49
errOAAI
errWansink, DG; van Herpen, REMA; Coerwinkel-Driessen, MM; Groenen, PJTA; Hemmings, BA; Wieringa, B
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Human NDR Kinases Control G1/S Cell Cycle Transition by Directly Regulating p21 Stability
err2023-03-20
err108
errOAAI
errCornils, Hauke; Kohler, Reto S.; Hergovich, Alexander; Hemmings, Brian A.
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Differential Effects of Protein Kinase B/Akt Isoforms on Glucose Homeostasis and Islet Mass
err2023-03-20
err64
errOAAI
errBuzzi, Francesca; Xu, Linhua; Zuellig, Richard A.; Boller, Simone B.; Spinas, Giatgen A.; Hynx, Debby; Chang, Zai; Yang, Zhongzhou; Hemmings, Brian A.; Tschopp, Oliver; Niessen, Markus
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Acyl Coenzyme A Thioesterase Them5/Acot15 Is Involved in Cardiolipin Remodeling and Fatty Liver Development
err2023-03-20
err62
errOAAI
errZhuravleva, Elena; Gut, Heinz; Hynx, Debby; Marcellin, David; Bleck, Christopher K. E.; Genoud, Christel; Cron, Peter; Keusch, Jeremy J.; Dummler, Bettina; Esposti, Mauro Degli; Hemmings, Brian A.
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PKB/Akt-dependent regulation of inflammation in cancer
err2018-02-01
err78
errOAAI
errTang, Fengyuan; Wang, Yuhua; Hemming, Brian A.; Ruegg, Curzio; Xue, Gongda
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SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment
err2018-02-01
err36
errOAAI
errMoncayo, Gerald; Grzmil, Michal; Smirnova, Tatiana; Zmarz, Pawel; Huber, Roland M.; Hynx, Debby; Kohler, Hubertus; Wang, Yuhua; Hotz, Hans-Rudolf; Hynes, Nancy E.; Keller, Georg; Frank, Stephan; Merlo, Adrian; Hemmings, Brian A.
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Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy
err2016-09-01
err46
PREAI
errGrzmil, Michal; Seebacher, Jan; Hess, Daniel; Behe, Martin; Schibli, Roger; Moncayo, Gerald; Frank, Stephan; Hemmings, Brian A.
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ACQUIRED RESISTANCE TO CLINICAL CANCER THERAPY: A TWIST IN PHYSIOLOGICAL SIGNALING
err2016-07-01
err53
errOAAI
errWicki, Andreas; Mandala, Mario; Massi, Daniela; Taverna, Daniela; Tang, Huifang; Hemmings, Brian A.; Xue, Gongda
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The kinases NDR1/2 act downstream of the Hippo homolog MST1 tomediate both egress of thymocytes from the thymus and lymphocyte motility
err2015-10-06
err67
PREAI
errTang, Fengyuan; Gill, Jason; Ficht, Xenia; Barthlott, Thomas; Cornils, Hauke; Schmitz-Rohmer, Debora; Hynx, Debby; Zhou, Dawang; Zhang, Lei; Xue, Gongda; Grzmil, Michal; Yang, Zhongzhou; Hergovich, Alexander; Hollaender, Georg A.; Stein, Jens V.; Hemmings, Brian A.; Matthias, Patrick
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