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In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma Yu, Kwanha; Kong, Kathleen; Lozzi, Brittney; Luna-Figueroa, Estefania; Cervantes, Alexis; Curry, Rachel; Mohila, Carrie A.; Rao, Ganesh; Jalali, Ali; Mills, Gordon B.; Scott, Kenneth L.; Deneen, Benjamin Share Save
A functional genomic approach to actionable gene fusions for precision oncology Li, Jun; Lu, Hengyu; Ng, Patrick Kwok-Shing; Pantazi, Angeliki; Ip, Carman Ka Man; Jeong, Kang Jin; Amador, Bianca; Tran, Richard; Tsang, Yiu Huen; Yang, Lixing; Song, Xingzhi; Dogruluk, Turgut; Ren, Xiaojia; Hadjipanayis, Angela; Bristow, Christopher A.; Lee, Semin; Kucherlapati, Melanie; Parfenov, Michael; Tang, Jiabin; Seth, Sahil; Mahadeshwar, Harshad S.; Mojumdar, Kamalika; Zeng, Dong; Zhang, Jianhua; Protopopov, Alexei; Seidman, Jonathan G.; Creighton, Chad J.; Lu, Yiling; Sahni, Nidhi; Shaw, Kenna R.; Meric-Bernstam, Funda; Futreal, Andrew; Chin, Lynda; Scott, Kenneth L.; Kucherlapati, Raju; Mills, Gordon B.; Liang, Han Share Save
POT1 Regulates Proliferation and Confers Sexual Dimorphism in Glioma Jalali, Ali; Yu, Kwanha; Beechar, Vivek; Huerta, Navish A. Bosquez; Grichuk, Anthony; Mehra, Deepika; Lozzi, Brittney; Kong, Kathleen; Scott, Kenneth L.; Rao, Ganesh; Bainbridge, Matthew N.; Bondy, Melissa L.; Deneen, Benjamin Share Save
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Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression Tsang, Yiu Huen; Wang, Yumeng; Kong, Kathleen; Grzeskowiak, Caitlin; Zagorodna, Oksana; Dogruluk, Turgut; Lu, Hengyu; Villafane, Nicole; Bhavana, Venkata Hemanjani; Moreno, Daniela; Elsea, Sarah H.; Liang, Han; Mills, Gordon B.; Scott, Kenneth L. Share Save
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PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma Tan, Xiaochao; Banerjee, Priyam; Pham, Edward A.; Rutaganira, Florentine U. N.; Basu, Kaustabh; Bota-Rabassedas, Neus; Guo, Hou-Fu; Grzeskowiak, Caitlin L.; Liu, Xin; Yu, Jiang; Shi, Lei; Peng, David H.; Rodriguez, B. Leticia; Zhang, Jiaqi; Zheng, Veronica; Duose, Dzifa Y.; Solis, Luisa M.; Mino, Barbara; Raso, Maria Gabriela; Behrens, Carmen; Wistuba, Ignacio I.; Scott, Kenneth L.; Smith, Mark; Khanh Nguyen; Lam, Grace; Choong, Ingrid; Mazumdar, Abhijit; Hill, Jamal L.; Gibbons, Don L.; Brown, Powel H.; Russell, William K.; Shokat, Kevan; Creighton, Chad J.; Glenn, Jeffrey S.; Kurie, Jonathan M. Share Save
Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies Ip, Carman K. M.; Ng, Patrick K. S.; Jeong, Kang Jin; Shao, S. H.; Ju, Zhenlin; Leonard, P. G.; Hua, Xu; Vellano, Christopher P.; Woessner, Richard; Sahni, Nidhi; Scott, Kenneth L.; Mills, Gordon B. Share Save
Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2 Choi, Byung-Kwon; Dayaram, Tajhal; Parikh, Neha; Wilkins, Angela D.; Nagarajan, Meena; Novikov, Ilya B.; Bachman, Benjamin J.; Jung, Sung Yun; Haas, Peter J.; Labrie, Jacques L.; Pickering, Curtis R.; Adikesavan, Anbu K.; Regenbogen, Sam; Kato, Linda; Lelescu, Ana; Buchovecky, Christie M.; Zhang, Houyin; Bao, Sheng Hua; Boyer, Stephen; Weber, Griff; Scott, Kenneth L.; Chen, Ying; Spangler, Scott; Donehower, Lawrence A.; Lichtarge, Olivier Share Save
RNA editing derived epitopes function as cancer antigens to elicit immune responses Zhang, Minying; Fritsche, Jens; Roszik, Jason; Williams, Leila J.; Peng, Xinxin; Chiu, Yulun; Tsou, Chih-Chiang; Hoffgaard, Franziska; Goldfinger, Valentina; Schoor, Oliver; Talukder, Amjad; Forget, Marie A.; Haymaker, Cara; Bernatchez, Chantale; Han, Leng; Tsang, Yiu-Huen; Kong, Kathleen; Xu, Xiaoyan; Scott, Kenneth L.; Singh-Jasuja, Harpreet; Lizee, Greg; Liang, Han; Weinschenk, Toni; Mills, Gordon B.; Hwu, Patrick Share Save
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer Grzeskowiak, Caitlin L.; Kundu, Samrat T.; Mo, Xiulei; Ivanov, Andrei A.; Zagorodna, Oksana; Lu, Hengyu; Chapple, Richard H.; Tsang, Yiu Huen; Moreno, Daniela; Mosqueda, Maribel; Eterovic, Karina; Fradette, Jared J.; Ahmad, Sumreen; Chen, Fengju; Chong, Zechen; Chen, Ken; Creighton, Chad J.; Fu, Haian; Mills, Gordon B.; Gibbons, Don L.; Scott, Kenneth L. Share Save
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The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network (vol 128, pg 1267, 2018) Tan, Xiaochao; Banerjee, Priyam; Liu, Xin; Yu, Jiang; Gibbons, Don L.; Wu, Ping; Scott, Kenneth L.; Diao, Lixia; Zheng, Xiaofeng; Wang, Jing; Jalali, Ali; Suraokar, Milind; Fujimoto, Junya; Behrens, Carmen; Liu, Xiuping; Liu, Chang-Gong; Creighton, Chad J.; Wistuba, Ignacio I.; Kurie, Jonathan M. Share Save
A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis Powell, Emily; Shao, Jiansu; Picon, Hector M.; Bristow, Christopher; Ge, Zhongqi; Peoples, Michael; Robinson, Frederick; Jeter-Jones, Sabrina L.; Schlosberg, Christopher; Grzeskowiak, Caitlin L.; Yang, Fei; Wu, Yun; Wistuba, Ignacio; Moulder, Stacy L.; Symmans, William F.; Scott, Kenneth L.; Edwards, John R.; Liang, Han; Heffernan, Timothy P.; Piwnica-Worms, Helen Share Save
Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer Nair, Amritha; Chung, Hsiang-Ching; Sun, Tingting; Tyagi, Siddhartha; Dobrolecki, Lacey E.; Dominguez-Vidana, Rocio; Kurley, Sarah J.; Orellana, Mayra; Renwick, Alexander; Henke, David M.; Katsonis, Panagiotis; Schmitt, Earlene; Chan, Doug W.; Li, Hui; Mao, Sufeng; Petrovic, Ivana; Creighton, Chad J.; Gutierrez, Carolina; Dubrulle, Julien; Stossi, Fabio; Tyner, Jeffrey W.; Lichtarge, Olivier; Lin, Charles Y.; Zhang, Bing; Scott, Kenneth L.; Hilsenbeck, Susan G.; Sun, Jinpeng; Yu, Xiao; Osborne, C. Kent; Schiff, Rachel; Christensen, James G.; Shields, David J.; Rimawi, Mothaffar F.; Ellis, Matthew J.; Shaw, Chad A.; Lewis, Michael T.; Westbrook, Thomas F. Share Save
The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network Tan, Xiaochao; Banerjee, Priyam; Liu, Xin; Yu, Jiang; Gibbons, Don L.; Wu, Ping; Scott, Kenneth L.; Diao, Lixia; Zheng, Xiaofeng; Wang, Jing; Jalali, Ali; Suraokar, Milind; Fujimoto, Junya; Behrens, Carmen; Liu, Xiuping; Liu, Chang-gong; Creighton, Chad J.; Wistuba, Ignacio I.; Kurie, Jonathan M. Share Save
Daam2 driven degradation of VHL promotes gliomagenesis Zhu, Wenyi; Krishna, Saritha; Garcia, Cristina; Lin, Chia-Ching John; Mitchell, Bartley D.; Scott, Kenneth L.; Mohila, Carrie A.; Creighton, Chad J.; Yoo, Seung-Hee; Lee, Hyun Kyoung; Deneen, Benjamin Share Save
HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer Xu, Xiaowei; De Angelis, Carmine; Burke, Kathleen A.; Nardone, Agostina; Hu, Huizhong; Qin, Lanfang; Veeraraghavan, Jamunarani; Sethunath, Vidyalakshmi; Heiser, Laura M.; Wang, Nicholas; Ng, Charlotte K. Y.; Chen, Edward S.; Renwick, Alexander; Wang, Tao; Nanda, Sarmistha; Shea, Martin; Mitchell, Tamika; Rajendran, Mahitha; Waters, Ian; Zabransky, Daniel J.; Scott, Kenneth L.; Gutierrez, Carolina; Nagi, Chandandeep; Geyer, Felipe C.; Chamness, Gary C.; Park, Ben H.; Shaw, Chad A.; Hilsenbeck, Susan G.; Rimawi, Mothaffar F.; Gray, Joe W.; Weigelt, Britta; Reis-Filho, Jorge S.; Osborne, C. Kent; Schiff, Rachel Share Save
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