arrow
Back
M

Melvin I. Simon

University of California System

122H-index
457Paper Count
4.5WCitation Count
Published Papers 85
Publication Date
Cellular and bioenergetic dysfunction induced by loss of the Wolfram Syndrome protein, Miner1, can be reversed by treatment with N-acetylcysteine
err2013-11-01
err1
PREAI
errWiley, Sandra E.; Andreyev, Alexander Y.; Divakaruni, Ajit S.; Karisch, Robert; Perkins, Guy; van der Geer, Peter; Tsai, Ting-Fen; Simon, Melvin I.; Neel, Benjamin G.; Dixon, Jack E.; Murphy, Anne N.
errShare
errSave
Acute, pharmacologic inhibition of the mitochondrial pyruvate carrier enhances cellular glucose uptake and potentiates metabolic flexibility
err2013-11-01
err0
PREAI
errDivakaruni, Ajit S.; Wiley, Sandra E.; Rogers, George W.; Simon, Melvin I.; Ciaraldi, Theodore P.; Murphy, Anne N.
errShare
errSave
Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+homeostasis
err2013-05-24
err101
errOAAI
errWiley, Sandra E.; Andreyev, Alexander Y.; Divakaruni, Ajit S.; Karisch, Robert; Perkins, Guy; Wall, Estelle A.; van der Geer, Peter; Chen, Yi-Fan; Tsai, Ting-Fen; Simon, Melvin I.; Neel, Benjamin G.; Dixon, Jack E.; Murphy, Anne N.
errShare
errSave
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier
err2013-03-19
err271
errOAAI
errDivakaruni, Ajit S.; Wiley, Sandra E.; Rogers, George W.; Andreyev, Alexander Y.; Petrosyan, Susanna; Loviscach, Mattias; Wall, Estelle A.; Yadava, Nagendra; Heuck, Alejandro P.; Ferrick, David A.; Henry, Robert R.; McDonald, William G.; Colca, Jerry R.; Simon, Melvin I.; Ciaraldi, Theodore P.; Murphy, Anne N.
errShare
errSave
PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12
err2012-05-20
err155
errOAAI
errGan, Xiaoqing; Wang, Jiyong; Wang, Chen; Sommer, Eeva; Kozasa, Tohru; Srinivasula, Srinivasa; Alessi, Dario; Offermanns, Stefan; Simon, Melvin I.; Wu, Dianqing
errShare
errSave
Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons
err2011-02-07
err91
errOAAI
errKim, Se-Jeong; Park, Goon Ho; Kim, Donghoon; Lee, Jaekwang; Min, Hyejung; Wall, Estelle; Lee, C. Justin; Simon, Melvin I.; Lee, Sung Joong; Han, Sang-Kyou
errShare
errSave
Synergistic Ca2+ Responses by Gαi- and Gαq-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβγ and Gαq
err2011-01-01
err60
errOAAI
errRebres, Robert A.; Roach, Tamara I. A.; Fraser, Iain D. C.; Philip, Finly; Moon, Christina; Lin, Keng-Mean; Liu, Jamie; Santat, Leah; Cheadle, Lucas; Ross, Elliott M.; Simon, Melvin I.; Seaman, William E.
errShare
errSave
Variability in G-Protein-Coupled Signaling Studied with Microfluidic Devices
err2010-10-01
err25
errOAAI
errBao, Xiaoyan Robert; Fraser, Iain D. C.; Wall, Estelle A.; Quake, Stephen R.; Simon, Melvin I.
errShare
errSave
Gαq-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity
err2010-07-12
err39
errOAAI
errMisra, Ravi S.; Shi, Guixiu; Moreno-Garcia, Miguel E.; Thankappan, Anil; Tighe, Michael; Mousseau, Betty; Kusser, Kim; Becker-Herman, Shirly; Hudkins, Kelly L.; Dunn, Robert; Kehry, Marilyn R.; Migone, Thi-Sau; Marshak-Rothstein, Ann; Simon, Melvin; Randall, Troy D.; Alpers, Charles E.; Liggitt, Denny; Rawlings, David J.; Lund, Frances E.
errShare
errSave
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
err2009-07-07
err415
errOAAI
errImamachi, Noritaka; Park, Goon Ho; Lee, Hyosang; Anderson, David J.; Simon, Melvin I.; Basbaum, Allan I.; Han, Sang-Kyou
errShare
errSave
Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105
err2009-06-16
err180
errOAAI
errWall, Estelle A.; Zavzavadjian, Joelle R.; Chang, Mi Sook; Randhawa, Baljinder; Zhu, Xiaocui; Hsueh, Robert C.; Liu, Jamie; Driver, Adrienne; Bao, Xiaoyan Robert; Sternweis, Paul C.; Simon, Melvin I.; Fraser, Iain D. C.
errShare
errSave
Deciphering Signaling Outcomes from a System of Complex Networks
err2009-05-19
err39
errOAAI
errHsueh, Robert C.; Natarajan, Madhusudan; Fraser, Iain; Pond, Blake; Liu, Jamie; Mumby, Susanne; Han, Heping; Jiang, Lily I.; Simon, Melvin I.; Taussig, Ronald; Sternweis, Paul C.
errShare
errSave
Molecular architecture of Gαo and the structural basis for RGS16-mediated deactivation
err2008-04-29
err72
errOAAI
errSlep, Kevin C.; Kercher, Michele A.; Wieland, Thomas; Chen, Ching-Kang; Simon, Melvin I.; Sigler, Paul B.
errShare
errSave
Identification of an alternative Gαq-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes
err2007-10-15
err84
errOAAI
errShi, Guixiu; Partida-Sanchez, Santiago; Misra, Ravi S.; Tighe, Michael; Borchers, Michael T.; Lee, James J.; Simon, Melvin I.; Lund, Frances E.
errShare
errSave
Gαi2-mediated signaling events in the endotheliurn are involved in controlling leukocyte extravasation
err2007-03-13
err56
errOAAI
errPero, Ralph S.; Borchers, Michael T.; Spicher, Karsten; Ochkur, Sergei I.; Sikora, Lyudmila; Rao, Savita P.; Abdala-Valencia, Hiam; O'Neill, Katie R.; Shen, Huahao; McGarry, Michael P.; Lee, Nancy A.; Cook-Mills, Joan M.; Sriramarao, P.; Simon, Melvin I.; Birnbaumer, Lutz; Lee, James J.
errShare
errSave
The alliance for cellular signaling plasmid collection: A flexible resource for protein localization studies and signaling pathway analysis
err2007-03-01
err14
errOAAI
errZavzavadjian, Joelle R.; Couture, Sam; Park, Wei Sun; Whalen, James; Lyon, Stephen; Lee, Genie; Fung, Eileen; Mi, Qingli; Liu, Jamie; Wall, Estelle; Santat, Leah; Dhandapani, Kavitha; Kivork, Christine; Driver, Adrienne; Zhu, Xiaocui; Chang, Mi Sook; Randhawa, Baljinder; Gehrig, Elizabeth; Bryan, Heather; Verghese, Mary; Maer, Andreia; Saunders, Brian; Ning, Yuhong; Subramaniam, Shankar; Meyer, Tobias; Simon, Melvin I.; O'Rourke, Nancy; Chandy, Grischa; Fraser, Iain D. C.
errShare
errSave
Extravasation of leukocytes from circulations is controlled by Gαi2 signaling events in the endothelium
err2007-01-01
err0
errOAAI
errPero, R. S.; Borchers, M. T.; Spicher, K.; Ochkur, S. I.; Sikora, L.; Rao, S. P.; O'Neill, K. R.; Abdala-Valencia, H.; Shen, H.; Simon, M. I.; McGarry, M. P.; Lee, N. A.; Cook-Mills, J. M.; Sriramarao, P.; Birnbaumer, L.; Lee, J. J.
errShare
errSave
Dual ligand stimulation of RAW 264.7 cells uncovers feedback mechanisms that regulate TLR-mediated gene expression
err2006-10-01
err21
errOAAI
errZhu, Xiaocui; Chang, Mi Sook; Hsueh, Robert C.; Taussig, Ron; Smith, Kelly D.; Simon, Melvin I.; Choi, Sangdun
errShare
errSave
A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression
err2006-09-12
err339
errOAAI
errShin, Kum-Joo; Wall, Estelle A.; Zavzavadjian, Joelle R.; Santat, Leah A.; Liu, Jamie; Hwang, Jong-Ik; Rebres, Robert; Roach, Tamara; Seaman, William; Simon, Melvin I.; Fraser, Iain D. C.
errShare
errSave