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Philip Leder

Harvard University

133H-index
472Paper Count
7.4WCitation Count
Published Papers 66
Publication Date
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Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err88
errOAAI
errMartin, S; Leder, P
errShare
errSave
Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err103
errOAAI
errEcsedy, JA; Michaelson, JS; Leder, P
errShare
errSave
Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary gland
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err62
errOAAI
errVollrath, B; Pudney, J; Asa, S; Leder, P; Fitzgerald, K
errShare
errSave
Mutation of the Murine Bloom's syndrome gene produces global genome destabilization
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err41
errOAAI
errChester, Nicholas; Babbe, Holger; Pinkas, Jan; Manning, Charlene; Leder, Philip
errShare
errSave
Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err79
errOAAI
errWeiss, RS; Leder, P; Vaziri, C
errShare
errSave
The Bloom's syndrome helicase is critical for development and function of the αβ T-cell lineage
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err33
errOAAI
errBabbe, Holger; Chester, Nicholas; Leder, Philip; Reizis, Boris
errShare
errSave
A Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen
errPLOS GENETICS
IF3.7
err2009-06-19
err49
errOAAI
errRavi, Dashnamoorthy; Wiles, Amy M.; Bhavani, Selvaraj; Ruan, Jianhua; Leder, Philip; Bishop, Alexander J. R.
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errSave
Formin1 disruption confers oligodactylism and alters Bmp signaling
errHUMAN MOLECULAR GENETICS
IF3.2
err2009-04-20
err46
errOAAI
errZhou, Fen; Leder, Philip; Zuniga, Aimee; Dettenhofer, Markus
errShare
errSave
Genomic Instability Resulting from Blm Deficiency Compromises Development, Maintenance, and Function of the B Cell Lineage
errJOURNAL OF IMMUNOLOGY
IF3.4
err2009-01-01
err28
errOAAI
errBabbe, Holger; McMenamin, Jennifer; Hobeika, Elias; Wang, Jing; Rodig, Scott J.; Reth, Michael; Leder, Philip
errShare
errSave
A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints
errDEVELOPMENTAL CELL
IF8.7
err2008-10-01
err550
errOAAI
errLi, Xiajun; Ito, Mitsuteru; Zhou, Fen; Youngson, Neil; Zuo, Xiaopan; Leder, Philip; Ferguson-Smith, Anne C.
errShare
errSave
Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency
errONCOGENE
IF7.3
err2007-10-22
err1
PREAI
errLeder, A.; McMenamin, J.; Zhou, F.; Moran, J. L.; Beier, D. R.; Leder, P.
errShare
errSave
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2007-05-29
err72
errOAAI
errLu, Jianrong; Ruhf, Marie-Laure; Perrimon, Norbert; Leder, Philip
errShare
errSave
Mitochondriotoxic compounds for cancer therapy
errONCOGENE
IF7.3
err2006-08-07
err136
errOAAI
errFantin, V. R.; Leder, P.
errShare
errSave
Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2
errEXPERIMENTAL CELL RESEARCH
IF3.5
err2006-04-01
err50
PREAI
errZhou, F; Leder, P; Martin, SS
errShare
errSave
A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells
errCANCER RESEARCH
IF16.6
err2005-08-01
err53
errOAAI
errFantin, VR; Berardi, MJ; Babbe, H; Michelman, MV; Manning, CM; Leder, P
errShare
errSave
ζ-/- Thalassemic mice are affected by two modifying loci and display unanticipated somatic recombination leading to inherited variation
errHUMAN MOLECULAR GENETICS
IF3.2
err2005-01-13
err2
errOAAI
errLeder, A; McMenamin, J; Fontaine, K; Bishop, A; Leder, P
errShare
errSave
Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin
errIMMUNITY
IF26.3
err2004-07-01
err224
PREAI
errShigematsu, H; Reizis, B; Iwasaki, H; Mizuno, S; Hu, D; Traver, D; Leder, P; Sakaguchi, N; Akashi, K
errShare
errSave
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth
errONCOGENE
IF7.3
err2004-04-05
err70
PREAI
errMartin, SS; Ridgeway, AG; Pinkas, J; Lu, Y; Reginato, MJ; Koh, EY; Michelman, M; Daley, GQ; Brugge, JS; Leder, P
errShare
errSave
F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell
errCANCER RESEARCH
IF16.6
err2004-01-16
err84
PREAI
errFantin, VR; Leder, P
errShare
errSave
Chromosome instability and tumor predisposition inversely correlate with BLM protein levels
errDNA REPAIR
IF2.7
err2003-12-01
err50
PREAI
errMcDaniel, LD; Chester, N; Watson, M; Borowsky, AD; Leder, P; Schultz, RA
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Michel C. Nussenzweig
H-index: 183 · Papers: 617
S
Stephen J. Elledge
H-index: 172 · Papers: 542
N
Norbert Perrimon
H-index: 154 · Papers: 867
S
Steven M. Greenberg
H-index: 144 · Papers: 902
M
Marc E. Rothenberg
H-index: 137 · Papers: 1.4K
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