Not logged inAn activity-specificity trade-off encoded in human transcription factors
Naderi, Julian; Magalhaes, Alexandre P.; Kibar, Goezde; Stik, Gregoire; Zhang, Yaotian; Mackowiak, Sebastian D.; Wieler, Hannah M.; Rossi, Francesca; Buschow, Rene; Christou-Kent, Marie; Alcoverro-Bertran, Marc; Graf, Thomas; Vingron, Martin; Hnisz, Denes .png)
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SaveBCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cellsLiao, Rui; Wu, Yi; Qin, Le; Jiang, Zhiwu; Gou, Shixue; Zhou, Linfu; Hong, Qilan; Li, Yao; Shi, Jingxuan; Yao, Yao; Lai, Liangxue; Li, Yangqiu; Liu, Pentao; Thiery, Jean Paul; Qin, Dajiang; Graf, Thomas; Liu, Xingguo; Li, Peng Share Save CEBPA phase separation links transcriptional activity and 3D chromatin hubsChristou-Kent, Marie; Cuartero, Sergi; Garcia-Cabau, Carla; Ruehle, Julia; Naderi, Julian; Erber, Julia; Neguembor, Maria Victoria; Plana-Carmona, Marcos; Alcoverro-Bertran, Marc; De Andres-Aguayo, Luisa; Klonizakis, Antonios; Julia-Vilella, Eric; Lynch, Cian; Serrano, Manuel; Hnisz, Denes; Salvatella, Xavier; Graf, Thomas; Stik, Gregoire Share Save 3D chromatin reprogramming primes human memory TH2 cells for rapid recall and pathogenic dysfunctionOnrust-van Schoonhoven, Anne; de Bruijn, Marjolein J. W.; Stikker, Bernard; Brouwer, Rutger W. W.; Braunstahl, Gert-Jan; van IJcken, Wilfred F. J.; Graf, Thomas; Huylebroeck, Danny; Hendriks, Rudi W.; Stik, Gregoire; Stadhouders, Ralph Share Save The trophectoderm acts as a niche for the inner cell mass through C/EBPa-regulated IL-6 signalingPlana-Carmona, Marcos; Stik, Gregoire; Bulteau, Romain; Segura-Morales, Carolina; Alcazar, Noelia; Wyatt, Chris D. R.; Klonizakis, Antonios; de Andres-Aguayo, Luisa; Gasnier, Maxime; Tian, Tian, V; Torcal Garcia, Guillem; Vila-Casadesus, Maria; Plachta, Nicolas; Serrano, Manuel; Francesconi, Mirko; Graf, Thomas Share Save The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte developmentAzagra, Alba; Meler, Ainara; de Barrios, Oriol; Tomas-Daza, Laureano; Collazo, Olga; Monterde, Beatriz; Obiols, Mireia; Rovirosa, Llorenc; Vila-Casadesus, Maria; Cabrera-Pasadas, Monica; Gusi-Vives, Mar; Graf, Thomas; Varela, Ignacio; Sardina, Jose Luis; Javierre, Biola M.; Parra, Maribel Share Save CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cellsSoochit, Widia; Sleutels, Frank; Stik, Gregoire; Bartkuhn, Marek; Basu, Sreya; Hernandez, Silvia C.; Merzouk, Sarra; Vidal, Enrique; Boers, Ruben; Boers, Joachim; van der Reijden, Michael; Geverts, Bart; van Cappellen, Wiggert A.; van den Hout, Mirjam; Ozgur, Zeliha; van IJcken, Wilfred F. J.; Gribnau, Joost; Renkawitz, Rainer; Graf, Thomas; Houtsmuller, Adriaan; Grosveld, Frank; Stadhouders, Ralph; Galjart, Niels Share Save Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterningLebedeva, Tatiana; Aman, Andrew J.; Graf, Thomas; Niedermoser, Isabell; Zimmermann, Bob; Kraus, Yulia; Schatka, Magdalena; Demilly, Adrien; Technau, Ulrich; Genikhovich, Grigory Share Save Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1Vivori, Claudia; Papasaikas, Panagiotis; Stadhouders, Ralph; Di Stefano, Bruno; Rubio, Anna Ribo; Balaguer, Clara Berenguer; Generoso, Serena; Mallol, Anna; Sardina, Jose Luis; Payer, Bernhard; Graf, Thomas; Valcarcel, Juan Share Save Share Save The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiationVizan, Pedro; Gutierrez, Arantxa; Espejo, Isabel; Garcia-Montolio, Marc; Lange, Martin; Carretero, Ana; Lafzi, Atefeh; de Andres-Aguayo, Luisa; Blanco, Enrique; Thambyrajah, Roshana; Graf, Thomas; Heyn, Holger; Bigas, Anna; Di Croce, Luciano Share Save CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory responseStik, Gregoire; Vidal, Enrique; Barrero, Mercedes; Cuartero, Sergi; Vila-Casadesus, Maria; Mendieta-Esteban, Julen; Tian, Tian, V; Choi, Jinmi; Berenguer, Clara; Abad, Amaya; Borsari, Beatrice; le Dily, Francois; Cramer, Patrick; Marti-Renom, Marc A.; Stadhouders, Ralph; Graf, Thomas Share Save Share Save Share Save Whsc1 links pluripotency exit with mesendoderm specificationTian, Tian, V; Di Stefano, Bruno; Stik, Gregoire; Vila-Casadesus, Maria; Luis Sardina, Jose; Vidal, Enrique; Dasti, Alessandro; Segura-Morales, Carolina; De Andres-Aguayo, Luisa; Gomez, Antonio; Goldmann, Johanna; Jaenisch, Rudolf; Graf, Thomas Share Save Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogrammingFrancesconi, Mirko; Di Stefano, Bruno; Berenguer, Clara; de Andres-Aguayo, Luisa; Plana-Carmona, Marcos; Mendez-Lago, Maria; Guillaumet-Adkins, Amy; Rodriguez-Esteban, Gustavo; Gut, Marta; Gut, Ivo G.; Heyn, Holger; Lehner, Ben; Graf, Thomas Share Save Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate (vol 23, pg 727, 2018)Sardina, Jose Luis; Collombet, Samuel; Tian, Tian V.; Gomez, Antonio; Di Stefano, Bruno; Berenguer, Clara; Brumbaugh, Justin; Stadhouders, Ralph; Segura-Morales, Carolina; Gut, Marta; Gut, Ivo G.; Heath, Simon; Aranda, Sergi; Di Croce, Luciano; Hochedlinger, Konrad; Thieffry, Denis; Graf, Thomas Share Save Share Save Share Save 
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