Niels L. Mulder - Publications, H-index & Citations

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Niels L. Mulder

University Medical Center Groningen

18H-index

92Paper Count

1.4KCitation Count

Published Papers 26

Publication Date

Mice with humanized FXR ligand-binding domain display distinct metabolic responses upon pharmacological FXR stimulation

Journal of Lipid Research

IF4.1

2026-06-25

OAAI

Jinxiao Li; Hilde D. de Vries; Kirill Ustyantsev; Milaine V. Hovingh; Niels L. Mulder; Rick Havinga; Nicolette Huijkman; Sarah Falcone; Krisztina de Bruyn; Ellen Weersing; Niels J. Kloosterhuis; Marieke Smit; Eugene Berezikov; Bart van de Sluis; Henkjan J. Verkade; Folkert Kuipers; Jan Freark de Boer

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Generation and characterization of a mouse model for bile salt export pump deficiency with the p.E297G mutation

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

IF0

2025-10-17

PREAI

Antonia Felzen; Willemien F.J. Hof; Hilde de Vries; Milaine V. Hovingh; Rick Havinga; Niels L. Mulder; Martijn Koehorst; Niels Kloosterhuis; Marieke Smit; Nicolette Huijkman; Bart van de Sluis; Jan Freark de Boer; Folkert Kuipers; Henkjan J. Verkade

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Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70-/- mice

PEDIATRIC RESEARCH

IF3.1

2024-10-02

OAAI

de Vries, Hilde D.; Eijgenraam, Tim R.; Bloks, Vincent W.; Mulder, Niels L.; van Zutphen, Tim; Sillje, Herman H. W.; Kuipers, Folkert; de Boer, Jan Freark

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Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition

CLINICAL SCIENCE

IF7.7

2023-11-10

OAAI

Verkade, Esther; Shen, Wenqiang; Hovingh, Milaine, V; Mulder, Niels L.; de Bruyn, Krisztina; Koehorst, Martijn; de Vries, Hilde D.; Bloks, Vincent W.; Kuipers, Folkert; de Boer, Jan Freark

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Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition

BIOMEDICINES

IF3.9

2023-09-08

OAAI

Palmiotti, Anna; de Vries, Hilde D.; Hovingh, Milaine V.; Koehorst, Martijn; Mulder, Niels L.; Verkade, Esther; Veentjer, Melany K.; van Dijk, Theo H.; Bloks, Vincent W.; Havinga, Rick; Verkade, Henkjan J.; de Boer, Jan Freark; Kuipers, Folkert

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Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids

PEDIATRIC RESEARCH

IF3.1

2022-09-23

OAAI

de Vries, Hilde D.; Palmiotti, Anna; Li, Rumei; Hovingh, Milaine, V; Mulder, Niels L.; Koehorst, Martijn; Bloks, Vincent W.; van Zutphen, Tim; Kuipers, Folkert; de Boer, Jan Freark

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Increased prevalence of intellectual disabilities in higher-intensity mental healthcare settings

BJPSYCH OPEN

IF3.5

2021-04-22

OAAI

Nieuwenhuis, Jeanet G.; Lepping, Peter; Mulder, Niels L.; Nijman, Henk L. I.; Veereschild, Mike; Noorthoorn, Eric O.

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Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1d/- mice

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2021-04-01

OAAI

Guevara, Ana P. Huerta; McGowan, Sara J.; Kazantzis, Melissa; Stallons, Tania Rozgaja; Sano, Tokio; Mulder, Niels L.; Jurdzinski, Angelika; van Dijk, Theo H.; Eggen, Bart J. L.; Jonker, Johan W.; Niedernhofer, Laura J.; Kruit, Janine K.

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Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorption

JOURNAL OF LIPID RESEARCH

IF4.1

2021-01-01

OAAI

Li, Rumei; Palmiotti, Anna; de Vries, Hilde D.; Hovingh, Milaine, V; Koehorst, Martijn; Mulder, Niels L.; Zhang, Yue; Kats, Kim; Bloks, Vincent W.; Fu, Jingyuan; Verkade, Henkjan J.; de Boer, Jan Freark; Kuipers, Folkert

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Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2021-01-01

OAAI

de Boer, Jan Freark; de Vries, Hilde D.; Palmiotti, Anna; Li, Rumei; Doestzada, Marwah; Hoogerland, Joanne A.; Fu, Jingyuan; La Rose, Anouk M.; Westerterp, Marit; Mulder, Niels L.; Hovingh, Milaine, V; Koehorst, Martijn; Kloosterhuis, Niels J.; Wolters, Justina C.; Bloks, Vincent W.; Haas, Joel T.; Dombrowicz, David; Staels, Bart; van de Sluis, Bart; Kuipers, Folkert

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Symposium: Mental health law differences and coercive measures over four countries

EUROPEAN PSYCHIATRY

IF6.7

2020-03-23

PREAI

Noorthoorn, E.; Lepping, P.; Steinert, T.; Flammer, E.; Massood, B.; Mulder, N.

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A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

JOURNAL OF LIPID RESEARCH

IF4.1

2020-03-01

108

OAAI

de Boer, Jan Freark; Verkade, Esther; Mulder, Niels L.; de Vries, Hilde D.; Huijkman, Nicolette; Koehorst, Martijn; Boer, Theo; Wolters, Justina C.; Bloks, Vincent W.; van de Sluis, Bart; Kuipers, Folkert

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A HUMAN-LIKE COMPOSITION OF THE CIRCULATING BILE ACID POOL IMPACTS ON PLASMA LDL CHOLESTEROL IN MICE

ATHEROSCLEROSIS

IF5.7

2019-08-01

PREAI

De Boer, J. F.; de Vries, H. D.; Palmiotti, A.; Li, R.; Mulder, N. L.; Hovingh, M. V.; Koehorst, M.; Kloosterhuis, N. J.; Bloks, V. W.; van de Sluis, B.; Kuipers, F.

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Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice

HEPATOLOGY

IF15.8

2019-06-24

OAAI

Hoogerland, Joanne A.; Lei, Yu; Wolters, Justina C.; de Boer, Jan Freark; Bos, Trijnie; Bleeker, Aycha; Mulder, Niels L.; van Dijk, Theo H.; Kuivenhoven, Jan A.; Rajas, Fabienne; Mithieux, Gilles; Haeusler, Rebecca A.; Verkade, Henkjan J.; Bloks, Vincent W.; Kuipers, Folkert; Oosterveer, Maaike H.

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Mental health professionals' knowledge, skills and attitudes on domestic violence and abuse in the Netherlands: cross-sectional study

BJPSYCH OPEN

IF3.5

2019-03-07

OAAI

Ruijne, Roos E.; Kamperman, Astrid M.; Trevillion, Kylee; Garofalo, Carlo; Jongejan, Femke E.; Bogaerts, Stefan; Howard, Louise M.; Mulder, Niels L.

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AAV8-mediated gene transfer of microRNA-132 improves beta cell function in mice fed a high-fat diet

JOURNAL OF ENDOCRINOLOGY

IF3.9

2019-02-01

OAAI

Mulder, Niels L.; Havinga, Rick; Kluiver, Joost; Groen, Albert K.; Kruit, Janine K.

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Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

CELL METABOLISM

IF30.9

2019-02-01

210

OAAI

Guay, Claudiane; Kruit, Janine K.; Rome, Sophie; Menoud, Veronique; Mulder, Niels L.; Jurdzinski, Angelika; Mancarella, Francesca; Sebastiani, Guido; Donda, Alena; Gonzalez, Bryan J.; Jandus, Camilla; Bouzakri, Karim; Pinget, Michel; Boitard, Christian; Romero, Pedro; Dotta, Francesco; Regazzi, Romano

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FXR ACTIVATION NORMALIZES DYSLIPIDEMIA AND ALLEVIATES OBESITY IN WESTERN-TYPE DIET-FED APOE*3-LEIDEN.CETP TRANSGENIC MICE

ATHEROSCLEROSIS

IF5.7

2018-08-01

PREAI

Paalvast, Y.; Zhou, E.; Mulder, N. L.; Koehorst, M.; Boverhof, R.; van Dijk, K. Willems; Rensen, P. C. N.; Kuivenhoven, J. A.; Kremoser, C.; Wang, Y.; Kuipers, F.; Groen, A. K.; de Boer, J. F.

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Treatment results for severe psychiatric illness: which method is best suited to denote the outcome of mental health care?

BMC PSYCHIATRY

IF3.6

2018-07-13

OAAI

de Beurs, Edwin; Blankers, Matthijs; Delespaul, Philippe; van Duijn, Erik; Mulder, Niels; Nugter, Annet; Swildens, Wilma; Tiemens, Bea G.; Theunissen, Jan; van Voorst, Arno F. A.; van Weeghel, Jaap

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Associations between psychiatric symptoms and seclusion use: Clinical implications for care planning

INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING

IF3.3

2017-09-27

PREAI

van de Sande, Roland; Noorthoorn, Eric; Nijman, Henk; Wierdsma, Andre; van de Staak, Cees; Hellendoorn, Edwin; Mulder, Niels

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Research Directions