Not logged in Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease Tchernychev, Boris; Li, Huihui; Lee, Sung-Kyun; Gao, Xin; Ramanarasimhaiah, Raghunath; Liu, Guang; Hall, Katherine C.; Bernier, Sylvie G.; Jones, Juli E.; Feil, Susanne; Feil, Robert; Buys, Emmanuel S.; Graul, Regina M.; Frenette, Paul S.; Masferrer, Jaime L. Share Save
Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit Flores-Costa, Roger; Duran-Guell, Marta; Casulleras, Mireia; Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose; Diaz, Alba; Lozano, Juan J.; Titos, Esther; Hall, Katherine; Sarno, Renee; Masferrer, Jaime L.; Claria, Joan Share Save
Praliciguat inhibits progression of diabetic nephropathy in ZSF1 rats and suppresses inflammation and apoptosis in human renal proximal tubular cells Liu, Guang; Shea, Courtney M.; Jones, Juli E.; Price, Gavrielle M.; Warren, William; Lonie, Elisabeth; Yan, Shu; Currie, Mark G.; Profy, Albert T.; Masferrer, Jaime L.; Zimmer, Daniel P. Share Save
Metabolic Effects of Praliciguat, Empagliflozin, and Their Combination in Rats with Programmed Hypertension and Early Exposure to High-Fat Diet Schwartzkopf, Chad; Ribo, Virginia Reverte; Rodriguez, Francisca; Oltra, Lidia; Moreno Ayuso, Juan Manuel; Llinas, M. Teresa; Nicolas, Alejandro S.; Shea, Courtney; Currie, Mark; Jones, Juli E.; Buys, Emmanuel S.; Masferrer, Jaime; Salazar Aparicio, Francisco Javier Share Save
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Praliciguat, a Clinical-Stage sGC Stimulator, Improves Insulin Sensitivity, Lipid Tolerance, and Energy Utilization in a Mouse Diet-Induced Obesity Model Housed at Thermoneutrality Schwartzkopf, Chad; Hadcock, John; Roux, Julien; Liu, Guang; Shea, Courtney; Currie, Mark; Milne, G. Todd; Masferrer, Jaime; Jones, Juli E. Share Save
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Pharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease Tobin, Jenny, V; Zimmer, Daniel P.; Shea, Courtney; Germano, Peter; Bernier, Sylvie G.; Liu, Guang; Long, Kim; Miyashiro, Joy; Ranganath, Sheila; Jacobson, Sarah; Tang, Kim; Im, G-Yoon Jamie; Sheppeck, James, II; Moore, Joel D.; Sykes, Kristine; Wakefield, James; Sarno, Renee; Banijamali, Ali R.; Profy, Albert T.; Milne, G. Todd; Currie, Mark G.; Masferrer, Jaime L. Share Save
Stimulation of soluble guanylate cyclase inhibited fibrosis and inflammation in human liver microtissues and in an animal model of liver disease Hall, K.; Bernier, S.; Jacobson, S.; Liu, G.; Sarno, R.; Catanzano, V.; Sheppeck, J.; Hadcock, J.; Currie, M.; Masferrer, J. Share Save
The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis Flores-Costa, Roger; Alcaraz-Quiles, Jose; Titos, Esther; Lopez-Vicario, Cristina; Casulleras, Mireia; Duran-Guell, Marta; Rius, Bibiana; Diaz, Alba; Hall, Katherine; Shea, Courtney; Sarno, Renee; Currie, Mark; Masferrer, Jaime L.; Claria, Joan Share Save
The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis Flores-Costa, R.; Alcaraz-Quiles, J.; Titos, E.; Lopez-Vicario, C.; Casulleras, M.; Duran-Gell, M.; Rius, B.; Diaz, A.; Hall, K.; Shea, C.; Sarno, R.; Masferrer, J. L.; Claria, J. Share Save
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IMPACT OF TREATMENTS ON MAJOR IMMUNOLOGIC PATHWAYS IN SLE DEPENDS ON TYPE I INTERFERON SIGNATURE: ANALYSIS FROM BIOMARKERS OF LUPUS DISEASE (BOLD) STUDY Merrill, J. T.; Immermann, F. W.; Zhou, T.; O'Toole, M.; Whitley, M.; Hill, A. A.; Zhang, Y.; von Schack, D.; Reddy, P. S.; Masferrer, J. L.; Kamp, S.; Guthridge, J. M.; Thanou, A.; Wu, P.; Paradis, T.; Mounts, W. M.; James, J. A.; Sridharan, S. T. Share Save
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IMPACT OF BASELINE INTERFERON PATHWAY ACTIVATION ON WIDESPREAD GENE EXPRESSION CHANGES WITH DISEASE FLARE IN LUPUS PATIENTS: INTERIM REPORT FROM THE BOLD (BIOMARKERS OF LUPUS DISEASE) STUDY Seyhan, A.; O'Toole, M.; Zhang, Y.; Immermann, F. W.; Hill, A.; Reddy, P.; Masferrer, J.; Zhou, T.; Mounts, W.; Whitley, M.; Walker, T.; Kamp, S.; James, J.; Sridharan, S.; Merrill, J. T.; Honczarenko, M. Share Save
Anti-PDGF-B monoclonal antibody reduces liver fibrosis development Ogawa, Shinji; Ochi, Takashi; Shimada, Hideaki; Inagaki, Kazuyuki; Fujita, Isami; Nii, Aisuke; Moffat, Mark A.; Katragadda, Madan; Violand, Bernard N.; Arch, Robert H.; Masferrer, Jaime L. Share Save
A Novel Autotaxin Inhibitor Reduces Lysophosphatidic Acid Levels in Plasma and the Site of Inflammation Gierse, James; Thorarensen, Atli; Beltey, Konstantine; Bradshaw-Pierce, Erica; Cortes-Burgos, Luz; Hall, Troii; Johnston, Amy; Murphy, Michael; Nemirovskiy, Olga; Ogawa, Shinji; Pegg, Lyle; Pelc, Matthew; Prinsen, Michael; Schnute, Mark; Wendling, Jay; Wene, Steve; Weinberg, Robin; Wittwer, Arthur; Zweifel, Ben; Masferrer, Jaime Share Save
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