Not logged in Cooperative Hedgehog/GLI and JAK/STAT signaling drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer Elmer, Dominik P.; Stockmaier, Georg; Grund-Groeschke, Sandra; Strobl, Victoria; Dang, Hieu-Hoa; Wiederstein, Markus; Licha, David; Strobl, Anna; Eglseer, Anna; Sternberg, Christina; Tesanovic, Suzana; Gruber, Wolfgang; Wolff, Florian; Moriggl, Richard; Risch, Angela; Reischl, Roland; Huber, Christian G.; Krenn, Peter W.; Fortelny, Nikolaus; Horejs-Hoeck, Jutta; Aberger, Fritz Share Save
Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells Scheidt, Tamara; Alka, Oliver; Gonczarowska-Jorge, Humberto; Gruber, Wolfgang; Rathje, Florian; Dell'Aica, Margherita; Rurik, Marc; Kohlbacher, Oliver; Zahedi, Rene P.; Aberger, Fritz; Huber, Christian G. Share Save
Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinoma Sternberg, Christina; Gruber, Wolfgang; Eberl, Markus; Tesanovic, Suzana; Stadler, Manuela; Elmer, Dominik P.; Schlederer, Michaela; Grund, Sandra; Roos, Simone; Wolff, Florian; Kaur, Supreet; Mangelberger, Doris; Lehrach, Hans; Hache, Hendrik; Wierling, Christoph; Laimer, Josef; Lackner, Peter; Wiederstein, Markus; Kasper, Maria; Risch, Angela; Petzelbauer, Peter; Moriggl, Richard; Kenner, Lukas; Aberger, Fritz Share Save
Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance Gruber, Wolfgang; Peer, Elisabeth; Elmer, Dominik P.; Sternberg, Christina; Tesanovic, Suzana; del Burgo, Pedro; Coni, Sonia; Canettieri, Gianluca; Neureiter, Daniel; Bartz, Rene; Kohlhof, Hella; Vitt, Daniel; Aberger, Fritz Share Save
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Loss of IL-6/Stat3 signalling drives metastatic prostate cancer in mice and men Pencik, Jan; Schlederer, Michaela; Gruber, Wolfgang; Unger, Christine; Walker, Steven M.; Chalaris, Athena; Marie, Isabelle; Hassler, Melanie R.; Javaheri, Tahereh; Aksoy, Osman; Blayney, Jaine K.; Mazal, Peter; Grebien, Florian; Egger, Gerda; Poli, Valeria; Eferl, Robert; Kennedy, Richard; Fend, Falko; Scharpf, Marcus; Braun, Martin; Perner, Sven; Levy, David E.; Malcolm, Tim; Turner, Suzanne D.; Haitel, Andrea; Susani, Martin; Moazzami, Ali; Rose-Johns, Stefan; Aberger, Fritz; Merkel, Olaf; Moriggl, Richard; Culig, Zoran; Dolznig, Helmut; Kenner, Lukas Share Save
STAT3 regulated ARF expression suppresses prostate cancer metastasis Pencik, Jan; Schlederer, Michaela; Gruber, Wolfgang; Unger, Christine; Walker, Steven M.; Chalaris, Athena; Marie, Isabelle J.; Hassler, Melanie R.; Javaheri, Tahereh; Aksoy, Osman; Blayney, Jaine K.; Prutsch, Nicole; Skucha, Anna; Herac, Merima; Kraemer, Oliver H.; Mazal, Peter; Grebien, Florian; Egger, Gerda; Poli, Valeria; Mikulits, Wolfgang; Eferl, Robert; Esterbauer, Harald; Kennedy, Richard; Fend, Falko; Scharpf, Marcus; Braun, Martin; Perner, Sven; Levy, David E.; Malcolm, Tim; Turner, Suzanne D.; Haitel, Andrea; Susani, Martin; Moazzami, Ali; Rose-John, Stefan; Aberger, Fritz; Merkel, Olaf; Moriggl, Richard; Culig, Zoran; Dolznig, Helmut; Kenner, Lukas Share Save
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis Grabner, Beatrice; Schramek, Daniel; Mueller, Kristina M.; Moll, Herwig P.; Svinka, Jasmin; Hoffmann, Thomas; Bauer, Eva; Blaas, Leander; Hruschka, Natascha; Zboray, Katalin; Stiedl, Patricia; Nivarthi, Harini; Bogner, Edith; Gruber, Wolfgang; Mohr, Thomas; Zwick, Ralf Harun; Kenner, Lukas; Poli, Valeria; Aberger, Fritz; Stoiber, Dagmar; Egger, Gerda; Esterbauer, Harald; Zuber, Johannes; Moriggl, Richard; Eferl, Robert; Gyorffy, Balazs; Penninger, Josef M.; Popper, Helmut; Casanova, Emilio Share Save
IL-6/Stat3 signaling is an indispensable modulator of oncogene-induced cellular senescence Pencik, Jan; Schlederer, Michaela; Hassler, Melanie; Gruber, Wolfgang; Aberger, Fritz; Kennedy, Richard; Walker, Stephen; Rose-John, Stephan; Poli, Valeria; Eferl, Robert; Esterbauer, Harald; Aksoy, Osman; Herac, Merima; Mazal, Peter; Haitel, Andrea; Susani, Martin; Moriggl, Richard; Culig, Zoran; Kenner, Lukas Share Save
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Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis Chari, N. S.; Romano, R. A.; Koster, M. I.; Jaks, V.; Roop, D.; Flores, E. R.; Teglund, S.; Sinha, S.; Gruber, W.; Aberger, F.; Medeiros, L. J.; Toftgard, R.; McDonnell, T. J. Share Save
Inactivation of Patched1 in Mice Leads to Development of Gastrointestinal Stromal-Like Tumors That Express Pdgfrα but Not Kit Pelczar, Penelope; Zibat, Arne; van Dop, Willemijn A.; Heijmans, Jarom; Bleckmann, Annalen; Gruber, Wolfgang; Nitzki, Frauke; Uhmann, Anja; Guijarro, Maria V.; Hernando, Eva; Dittmann, Kai; Wienands, Juergen; Dressel, Ralf; Wojnowski, Leszek; Binder, Claudia; Taguchi, Takahiro; Beissbarth, Tim; Hogendoorn, Pancras C. W.; Antonescu, Cristina R.; Rubin, Brian P.; Schulz-Schaeffer, Walter; Aberger, Fritz; Van den Brink, Gijs R.; Hahn, Heidi Share Save
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