Not logged in MOSBY enables multi-omic inference and spatial biomarker discovery from whole slide images Senbabaoglu, Yasin; Prabhakar, Vignesh; Khormali, Aminollah; Eastham, Jeff; Liu, Evan; Warner, Elisa; Nabet, Barzin; Srivastava, Minu; Ballinger, Marcus; Liu, Kai Share Save
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer Taraborrelli, Lucia; Senbabaoglu, Yasin; Wang, Lifen; Lim, Junghyun; Blake, Kerrigan; Kljavin, Noelyn; Gierke, Sarah; Scherl, Alexis; Ziai, James; Mcnamara, Erin; Owyong, Mark; Rao, Shilpa; Calviello, Aslihan Karabacak; Oreper, Daniel; Jhunjhunwala, Suchit; Argiles, Guillem; Bendell, Johanna; Kim, Tae Won; Ciardiello, Fortunato; Wongchenko, Matthew J.; de Sauvage, Frederic J.; Melo, Felipe; Yan, Yibing; West, Nathaniel R.; Murthy, Aditya Share Save
CD8+T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy Huseni, Mahrukh A.; Wang, Lifen; Klementowicz, Joanna E.; Yuen, Kobe; Breart, Beatrice; Orr, Christine; Liu, Li-fen; Li, Yijin; Gupta, Vinita; Li, Congfen; Rishipathak, Deepali; Peng, Jing; Senbabaoglu, Yasin; Modrusan, Zora; Keerthivasan, Shilpa; Madireddi, Shravan; Chen, Ying-Jiun; Fraser, Eleanor J.; Leng, Ning; Hamidi, Habib; Koeppen, Hartmut; Ziai, James; Hashimoto, Kenji; Fasso, Marcella; Williams, Patrick; McDermott, David F.; Rosenberg, Jonathan E.; Powles, Thomas; Emens, Leisha A.; Hegde, Priti S.; Mellman, Ira; Turley, Shannon J.; Wilson, Mark S.; Mariathasan, Sanjeev; Molinero, Luciana; Merchant, Mark; West, Nathaniel R. Share Save
A PAN-CANCER MULTI-OMIC IMMUNE SINGLE-CELL ATLAS FOR CANCER IMMUNOTHERAPY: FOCUS ON CD4+T CELLS Mok, Lydia; Orlando, Andrea; Lehrer, Julian; Stuart, Joshua; Rudqvist, Nils-Petter; Vincent, Benjamin; Monette, Anne; Senbabaoglu, Yasin; Smith, Kellie; Thomas, Paul; Tschernia, Nicholas; Thorsson, Vesteinn; Zappasodi, Roberta; Jonsson, Vanessa Share Save
Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1 Keerthivasan, Shilpa; Senbabaoglu, Yasin; Martinez-Martin, Nadia; Husain, Bushra; Verschueren, Erik; Wong, Anne; Yang, Yeqing Angela; Sun, Yonglian; Pham, Victoria; Hinkle, Trent; Oei, Yoko; Madireddi, Shravan; Corpuz, Racquel; Tam, Lucinda; Carlisle, Samantha; Roose-Girma, Merone; Modrusan, Zora; Ye, Zhengmao; Koerber, James T.; Turley, Shannon J. Share Save
Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response Maculins, Timurs; Verschueren, Erik; Hinkle, Trent; Choi, Meena; Chang, Patrick; Chalouni, Cecile; Rao, Shilpa; Kwon, Youngsu; Lim, Junghyun; Katakam, Anand Kumar; Kunz, Ryan C.; Erickson, Brian K.; Huang, Ting; Tsai, Tsung-Heng; Vitek, Olga; Reichelt, Mike; Senbabaoglu, Yasin; Mckenzie, Brent; Rohde, John R.; Dikic, Ivan; Kirkpatrick, Donald S.; Murthy, Aditya Share Save
Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues Kapoor, Varun N.; Muller, Soren; Keerthivasan, Shilpa; Brown, Markus; Chalouni, Cecile; Storm, Elaine E.; Castiglioni, Alessandra; Lane, Ryan; Nitschke, Maximilian; Dominguez, Claudia X.; Astarita, Jillian L.; Krishnamurty, Akshay T.; Carbone, Catherine B.; Senbabaoglu, Yasin; Wang, Amber W.; Wu, Xiumin; Cremasco, Viviana; Roose-Girma, Merone; Tam, Lucinda; Doerr, Jonas; Chen, Mark Z.; Lee, Wyne P.; Modrusan, Zora; Yang, Yeqing Angela; Bourgon, Richard; Sandoval, Wendy; Shaw, Andrey S.; de Sauvage, Frederic J.; Mellman, Ira; Moussion, Christine; Turley, Shannon J. Share Save
CTLA-4 BLOCKADE PROMOTES TREG GLUCOSE METABOLISM AND REDUCES TREG FUNCTIONAL STABILITY IN GLYCOLYSIS-DEFECTIVE TUMORS Zappasodi, Roberta; Serganova, Inna; Cohen, Ivan; Maeda, Masatomo; Senbabaoglu, Yasin; Shindo, Masahiro; Maniyar, Rachana; Mane, Mayuresh; Leftin, Avigdor; Watson, McLane; Verma, Svena; Lubin, Matthew; Ko, Myat Kyaw; Ghosh, Arnab; Abu-Akeel, Mohsen; Ackerstaff, Ellen; Koutcher, Jason; Ho, Ping-Chih; Delgoffe, Greg; Blasberg, Ronald; Wolchok, Jedd; Merghoub, Taha Share Save
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CTLA-4 blockade drives loss of regulatory T cell functional stability in glycolysis defective tumors Zappasodi, Roberta; Serganova, Inna; Cohen, Ivan; Maeda, Masatomo; Shindo, Masahiro; Senbabaoglu, Yasin; Leftin, Avigdor; Maniyar, Rachana; Verma, Svena; Lubin, Matthew; Ko, Myat Kyaw; Mane, Mayuresh M.; Ghosh, Arnab; Ackerstaff, Ellen; Koutcher, Jason A.; Ho, Ping-Chih; Delgoffe, Greg M.; Blasberg, Ronald; Wolchok, Jedd D.; Merghoub, Taha Share Save
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy Dominguez, Claudia X.; Mueller, Soren; Keerthivasan, Shilpa; Koeppen, Hartmut; Hung, Jeffrey; Gierke, Sarah; Breart, Beatrice; Foreman, Oded; Bainbridge, Travis W.; Castiglioni, Alessandra; Senbabaoglu, Yasin; Modrusan, Zora; Liang, Yuxin; Junttila, Melissa R.; Klijn, Christiaan; Bourgon, Richard; Turley, Shannon J. Share Save
Genomic and Transcriptomic Characterization of Papillary Microcarcinomas With Lateral Neck Lymph Node Metastases Perera, Dilmi; Ghossein, Ronald; Camacho, Niedzica; Senbabaoglu, Yasin; Seshan, Venkatraman; Li, Juan; Bouvier, Nancy; Boucai, Laura; Viale, Agnes; Socci, Nicholas D.; Untch, Brian R.; Gonen, Mithat; Knauf, Jeffrey; Fagin, James A.; Berger, Michael; Tuttle, R. Michael Share Save
A balance of genomic instability, tumor-immune contexture and TGF-β signaling contributing to exclusion of T cells governs response to PD-L1 checkpoint blockade Mariathasan, Sanjeev; Turley, Shannon J.; Nickles, Dorothee; Castiglioni, Alessandra; Yuen, Kobe; Wang, Yulei; Kadel, Edward E.; Koeppen, Hartmut; Astarita, Jillian L.; Cubas, Rafael; Jhunjhunwala, Suchit; Yang, Yagai; Senbabaoglu, Yasin; Mellman, Ira; Chen, Daniel S.; Hegde, Priti; Bourgon, Richard; Powles, Thomas Share Save
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling Samie, Mohammad; Lim, Junghyun; Verschueren, Erik; Baughman, Joshua M.; Peng, Ivan; Wong, Aaron; Kwon, Youngsu; Senbabaoglu, Yasin; Hackney, Jason A.; Keir, Mary; Mckenzie, Brent; Kirkpatrick, Donald S.; Campagne, Menno van Lookeren; Murthy, Aditya Share Save
Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures (vol 17, 231, 2016) Senbabaoglu, Yasin; Gejman, Ron S.; Winer, Andrew G.; Liu, Ming; Van Allen, Eliezer M.; de Velasco, Guillermo; Miao, Diana; Ostrovnaya, Irina; Drill, Esther; Luna, Augustin; Weinhold, Nils; Lee, William; Manley, Brandon J.; Khalil, Danny N.; Kaffenberger, Samuel D.; Chen, Yingbei; Danilova, Ludmila; Voss, Martin H.; Coleman, Jonathan A.; Russo, Paul; Reuter, Victor E.; Chan, Timothy A.; Cheng, Emily H.; Scheinberg, David A.; Li, Ming O.; Choueiri, Toni K.; Hsieh, James J.; Sander, Chris; Hakimi, A. Ari Share Save
Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures Senbabaoglu, Yasin; Gejman, Ron S.; Winer, Andrew G.; Liu, Ming; Van Allen, Eliezer M.; de Velasco, Guillermo; Miao, Diana; Ostrovnaya, Irina; Drill, Esther; Luna, Augustin; Weinhold, Nils; Lee, William; Manley, Brandon J.; Khalil, Danny N.; Kaffenberger, Samuel D.; Chen, Yingbei; Danilova, Ludmila; Voss, Martin H.; Coleman, Jonathan A.; Russo, Paul; Reuter, Victor E.; Chan, Timothy A.; Cheng, Emily H.; Scheinberg, David A.; Li, Ming O.; Choueiri, Toni K.; Hsieh, James J.; Sander, Chris; Hakimi, A. Ari Share Save
The head and neck cancer immune landscape and its immunotherapeutic implications Mandal, Rajarsi; Senbabaoglu, Yasin; Desrichard, Alexis; Havel, Jonathan J.; Dalin, Martin G.; Riaz, Nadeem; Lee, Ken-Wing; Ganly, Ian; Hakimi, A. Ari; Chan, Timothy A.; Morris, Luc G. T. Share Save
Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma Chen, Fengju; Zhang, Yiqun; Senbabaoglu, Yasin; Ciriello, Giovanni; Yang, Lixing; Reznik, Ed; Shuch, Brian; Micevic, Goran; De Velasco, Guillermo; Shinbrot, Eve; Noble, Michael S.; Lu, Yiling; Covington, Kyle R.; Xi, Liu; Drummond, Jennifer A.; Muzny, Donna; Kang, Hyojin; Lee, Junehawk; Tamboli, Pheroze; Reuter, Victor; Shelley, Carl Simon; Kaipparettu, Benny A.; Bottaro, Donald P.; Godwin, Andrew K.; Gibbs, Richard A.; Getz, Gad; Kucherlapati, Raju; Park, Peter J.; Sander, Chris; Henske, Elizabeth P.; Zhou, Jane H.; Kwiatkowski, David J.; Ho, Thai H.; Choueiri, Toni K.; Hsieh, James J.; Akbani, Rehan; Mills, Gordon B.; Hakimi, A. Ari; Wheeler, David A.; Creighton, Chad J. Share Save
Mitochondrial DNA copy number variation across human cancers Reznik, Ed; Miller, Martin L.; Senbabaoglu, Yasin; Riaz, Nadeem; Sarungbam, Judy; Tickoo, Satish K.; Al-Ahmadie, Hikmat A.; Lee, William; Seshan, Venkatraman E.; Hakimi, A. Ari; Sander, Chris Share Save
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