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J

Jeremy Saklatvala

university of oxford

72H-index
303Paper Count
1.6WCitation Count
Published Papers 64
Publication Date
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Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err388
errOAAI
errLasa, M; Mahtani, KR; Finch, A; Brewer, G; Saklatvala, J; Clark, AR
errShare
errSave
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err340
errOAAI
errLasa, M; Abraham, SM; Boucheron, C; Saklatvala, J; Clark, AR
errShare
errSave
Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err434
errOAAI
errMahtani, KR; Brook, M; Dean, JLE; Sully, G; Saklatvala, J; Clark, AR
errShare
errSave
Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err231
errOAAI
errLasa, M; Brook, M; Saklatvala, J; Clark, AR
errShare
errSave
Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err251
errOAAI
errBrook, M; Tchen, CR; Santalucia, T; McIlrath, J; Arthur, JSC; Saklatvala, J; Clark, AR
errShare
errSave
The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err279
errOAAI
errDean, JLE; Wait, R; Mahtani, KR; Sully, G; Clark, AR; Saklatvala, J
errShare
errSave
JNK-DEPENDENT MODULATION OF THE PROTEASE SECRETOME PROFILE OF OSTEOARTHRITIC CARTILAGE
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2018-04-01
err0
errOAAI
errIsmail, H. M.; Troeberg, L.; Vincent, T. L.; Saklatvala, J.
errShare
errSave
WHOLE BLOOD RNA TRANSCRIPTIONAL REGULATION AFTER ACUTE KNEE INJURY IS ASSOCIATED WITH CLINICAL OUTCOMES: EARLY DATA FROM THE KICK STUDY
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2017-04-01
err0
errOAAI
errChanalaris, A.; Willliams, A.; Saklatvala, J.; Vincent, T. L.; Watt, F. E.
errShare
errSave
Rapid Activation of Transforming Growth Factor β-Activated Kinase 1 in Chondrocytes by Phosphorylation and K63-Linked Polyubiquitination Upon Injury to Animal Articular Cartilage
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2017-02-27
err23
errOAAI
errIsmail, Heba M.; Didangelos, Athanasios; Vincent, Tonia L.; Saklatvala, Jeremy
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errSave
Acute Molecular Changes in Synovial Fluid Following Human Knee Injury: Association With Early Clinical Outcomes
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2016-08-25
err70
errOAAI
errWatt, Fiona E.; Paterson, Erin; Freidin, Andrew; Kenny, Mark; Judge, Andrew; Saklatvala, Jeremy; Williams, Andy; Vincent, Tonia L.
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errSave
SYNOVIAL FLUID BIOMARKERS OF THE ACUTE KNEE INJURY RESPONSE ARE ASSOCIATED WITH EARLY CLINICAL OUTCOMES
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2016-06-01
err0
PREAI
errWatt, F. E.; Paterson, E.; Freidin, A.; Kenny, M.; Judge, A.; Saklatvala, J.; Williams, A.; Vincent, T.
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errSave
JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2016-04-27
err49
errOAAI
errIsmail, Heba M.; Miotla-Zarebska, Jadwiga; Troeberg, Linda; Tang, Xiaodi; Stott, Bryony; Yamamoto, Kazuhiro; Nagase, Hideaki; Fosang, Amanda J.; Vincent, Tonia L.; Saklatvala, Jeremy
errShare
errSave
MOLECULAR CHANGES IN SYNOVIAL FLUID FOLLOWING HUMAN KNEE INJURY ARE ASSOCIATED WITH EARLY CLINICAL OUTCOMES
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2016-04-01
err0
errOAAI
errWatt, F. E.; Paterson, E.; Freidin, A.; Kenny, M.; Judge, A.; Saklatvala, J.; Williams, A.; Vincent, T.
errShare
errSave
TNFAIP6 AND SAA1 MRNA LEVELS ARE ELEVATED IN PERIPHERAL BLOOD CELLS FOLLOWING DESTABILISING KNEE INJURIES
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2016-04-01
err0
errOAAI
errChanalaris, A.; Paterson, E.; Freidin, A.; Kenny, M.; Saklatvala, J.; Williams, A.; Watt, F. E.; Vincent, T. L.
errShare
errSave
DIFFERENTIAL INFLAMMATORY GENE EXPRESSION PATTERNS IN JNK2 KNOCKOUT MICE IN RESPONSE TO IL1, CARTILAGE INJURY AND SURGICALLY INDUCED OSTEOARTHRITIS
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2016-04-01
err0
errOAAI
errIsmail, H. M.; Chanalaris, A.; Miotla-Zarebska, J.; Vincent, T. L.; Saklatvala, J.
errShare
errSave
Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin
errJOURNAL OF IMMUNOLOGY
IF3.4
err2015-07-01
err69
errOAAI
errRoss, Ewan A.; Smallie, Tim; Ding, Qize; O'Neil, John D.; Cunliffe, Helen E.; Tang, Tina; Rosner, Dalya R.; Klevernic, Iva; Morrice, Nicholas A.; Monaco, Claudia; Cunningham, Adam F.; Buckley, Christopher D.; Saklatvala, Jeremy; Dean, Jonathan L.; Clark, Andrew R.
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errSave
Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide
errJOURNAL OF IMMUNOLOGY
IF3.4
err2015-07-01
err61
errOAAI
errSmallie, Tim; Ross, Ewan A.; Ammit, Alaina J.; Cunliffe, Helen E.; Tang, Tina; Rosner, Dalya R.; Ridley, Michael L.; Buckley, Christopher D.; Saklatvala, Jeremy; Dean, Jonathan L.; Clark, Andrew R.
errShare
errSave
Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2015-06-26
err73
errOAAI
errIsmail, Heba M.; Yamamoto, Kazuhiro; Vincent, Tonia L.; Nagase, Hideaki; Troeberg, Linda; Saklatvala, Jeremy
errShare
errSave
Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2015-04-01
err68
errOAAI
errGardiner, M. D.; Vincent, T. L.; Driscoll, C.; Burleigh, A.; Bou-Gharios, G.; Saklatvala, J.; Nagase, H.; Chanalaris, A.
errShare
errSave
A SIGNIFICANT ROLE FOR THE JNK PATHWAY IN REGULATING INTERLEUKIN 1 INDUCED-AGGRECAN DEGRADATION IN HUMAN ARTICULAR CHONDROCYTES
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2015-04-01
err1
errOAAI
errIsmail, H. M.; Yamamoto, K.; Vincent, T.; Nagase, H.; Troeberg, L.; Saklatvala, J.
errShare
errSave

Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
L
Luke O'neill
H-index: 143 · Papers: 709
C
Christopher D. Buckley
H-index: 101 · Papers: 736
J
Jonathan A. Cooper
H-index: 100 · Papers: 307
H
Hideaki Nagase
H-index: 97 · Papers: 423
E
Edward A. Clark
H-index: 93 · Papers: 450
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