Bengt Samuelsson - Publications, H-index & Citations

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Bengt Samuelsson

Karolinska Institutet

112H-index

565Paper Count

5.4WCitation Count

Published Papers 56

Publication Date

Human leukocytes selectively convert 4S,5S-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-12-15

OAAI

Shay, Ashley E.; Nshimiyimana, Robert; Samuelsson, Bengt; Petasis, Nicos A.; Haeggstrom, Jesper Z.; Serhan, Charles N.

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Modulation of microRNA processing by 5-lipoxygenase

FASEB JOURNAL

IF4.2

2020-11-17

OAAI

Uebbing, Stella; Kreiss, Marius; Scholl, Friederike; Haefner, Ann-Kathrin; Sueruen, Duran; Garscha, Ulrike; Werz, Oliver; Basavarajappa, Devaraj; Samuelsson, Bengt; Radmark, Olof; Suess, Beatrix; Steinhilber, Dieter

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Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-03-27

OAAI

Basavarajappa, Devaraj; Uebbing, Stella; Kreiss, Marius; Lukic, Ana; Suess, Beatrix; Steinhilber, Dieter; Samuelsson, Bengt; Radmark, Olof

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Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1

CANCER LETTERS

IF10.1

2019-03-01

PREAI

Lukic, Ana; Wahlund, Casper J. E.; Gomez, Cristina; Brodin, Daniel; Samuelsson, Bengt; Wheelock, Craig E.; Gabrielsson, Susanne; Radmark, Olof

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Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-02-05

OAAI

Di Gennaro, Antonio; Araujo, Ana Carolina; Busch, Albert; Jin, Hong; Wagsater, Dick; Vorkapic, Emina; Caidahl, Kenneth; Eriksson, Per; Samuelsson, Bengt; Maegdefessel, Lars; Haeggstrom, Jesper Z.

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GM-CSF- and M-CSF-primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures

FASEB JOURNAL

IF4.2

2017-09-19

PREAI

Lukic, Ana; Larssen, Pia; Fauland, Alexander; Samuelsson, Bengt; Wheelock, Craig E.; Gabrielsson, Susanne; Radmark, Olof

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Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-08-21

OAAI

Stsiapanava, Alena; Samuelsson, Bengt; Haeggstrom, Jesper Z.

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Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2017-07-24

OAAI

Pace, Simona; Pergola, Carlo; Dehm, Friederike; Rossi, Antonietta; Gerstmeier, Jana; Troisi, Fabiana; Pein, Helmut; Schaible, Anja M.; Weinigel, Christina; Rummler, Silke; Northoff, Hinnak; Laufer, Stefan; Maier, Thorsten J.; Radmark, Olof; Samuelsson, Bengt; Koeberle, Andreas; Sautebin, Lidia; Werz, Oliver

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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4

JOURNAL OF LIPID RESEARCH

IF4.1

2016-09-01

OAAI

Lukic, Ana; Ji, Jie; Idborg, Helena; Samuelsson, Bengt; Palmberg, Lena; Gabrielsson, Susanne; Radmark, Olof

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A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-01-11

OAAI

Brock, Joseph S.; Hamberg, Mats; Balagunaseelan, Navisraj; Goodman, Michael; Morgenstern, Ralf; Strandback, Emilia; Samuelsson, Bengt; Rinaldo-Matthis, Agnes; Haeggstrom, Jesper Z.

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5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2015-04-01

420

PREAI

Radmark, Olof; Werz, Oliver; Steinhilber, Dieter; Samuelsson, Bengt

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Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-07-17

OAAI

Basavarajappa, Devaraj; Wan, Min; Lukic, Ana; Steinhilber, Dieter; Samuelsson, Bengt; Radmark, Olof

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Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-03-03

OAAI

Stsiapanava, Alena; Olsson, Ulrika; Wan, Min; Kleinschmidt, Thea; Rutishauser, Dorothea; Zubarev, Roman A.; Samuelsson, Bengt; Rinaldo-Matthis, Agnes; Haeggstrom, Jesper Z.

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A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2014-03-01

PREAI

Ryge, Marija Rakonjac; Tanabe, Michiharu; Provost, Patrick; Persson, Bengt; Chen, Xinsheng; Funk, Colin D.; Rinaldo-Matthis, Agnes; Hofmann, Bettina; Steinhilber, Dieter; Watanabe, Takashi; Samuelsson, Bengt; Radmark, Olof

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Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-12-05

OAAI

Haas, Ulrike; Raschperger, Elisabeth; Hamberg, Mats; Samuelsson, Bengt; Tryggvason, Karl; Haeggstrom, Jesper Z.

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Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors

FASEB JOURNAL

IF4.2

2011-01-12

PREAI

Esser, Julia; Gehrmann, Ulf; Salvado, M. Dolores; Wetterholm, Anders; Haeggstrom, Jesper Z.; Samuelsson, Bengt; Gabrielsson, Susanne; Scheynius, Annika; Radmark, Olof

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Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-11-15

OAAI

Di Gennaro, Antonio; Wagsater, Dick; Mayranpaa, Mikko I.; Gabrielsen, Anders; Swedenborg, Jesper; Hamsten, Anders; Samuelsson, Bengt; Eriksson, Per; Haeggstrom, Jesper Z.

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Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer

JOURNAL OF INTERNAL MEDICINE

IF9.2

2010-06-09

OAAI

Radmark, O.; Samuelsson, B.

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Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102

BIOCHEMICAL JOURNAL

IF4.3

2009-12-14

OAAI

Esser, Julia; Rakonjac, Marija; Hofmann, Bettina; Fischer, Lutz; Provost, Patrick; Schneider, Gisbert; Steinhilber, Dieter; Samuelsson, Bengt; Radmark, Olof

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Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-11-03

OAAI

Hanaka, Hiromi; Pawelzik, Sven-Christian; Johnsen, John Inge; Rakonjac, Marija; Terawaki, Kan; Rasmuson, Agnes; Sveinbjornsson, Baldur; Schumacher, Martin C.; Hamberg, Mats; Samuelsson, Bengt; Jakobsson, Per-Johan; Kogner, Per; Radmark, Olof

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Research Directions