Not logged in Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau Foster, Kelly; Manca, Matteo; McClure, Kim; Koivula, Pyry; Trojanowski, John Q.; Havas, Daniel; Chancellor, Sarah; Goldstein, Lee; Brunden, Kurt R.; Kraus, Allison; Ahlijanian, Michael K. Share Save
Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice Delizannis, Argyro Thalia; Nonneman, Annelies; Tsering, Wangchen; De Bondt, An; Van den Wyngaert, Ilse; Zhang, Bin; Meymand, Emily; Olufemi, Modupe F.; Koivula, Pyry; Maimaiti, Shaniya; Trojanowski, John Q.; Lee, Virginia M-Y; Brunden, Kurt R. Share Save
Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats Back, Susanne; Necarsulmer, Julie; Whitaker, Leslie R.; Coke, Lamarque M.; Koivula, Pyry; Heathward, Emily J.; Fortuno, Lowella, V; Zhang, Yajun; Yeh, C. Grace; Baldwin, Heather A.; Spencer, Morgan D.; Mejias-Aponte, Carlos A.; Pickel, James; Hoffman, Alexander F.; Spivak, Charles E.; Lupica, Carl R.; Underhill, Suzanne M.; Amara, Susan G.; Domanskyi, Andrii; Anttila, Jenni E.; Airavaara, Mikko; Hope, Bruce T.; Hamra, F. Kent; Richie, Christopher T.; Harvey, Brandon K. Share Save
A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model Zhang, Bin; Yao, Yuemang; Cornec, Anne-Sophie; Oukoloff, Killian; James, Michael J.; Koivula, Pyry; Trojanowski, John Q.; Smith, Amos B., III; Lee, Virginia M. -Y.; Ballatore, Carlo; Brunden, Kurt R. Share Save
Lateral Hypothalamic GABAergic Neurons Encode Reward Predictions that Are Relayed to the Ventral Tegmental Area to Regulate Learning Sharpe, Melissa J.; Marchant, Nathan J.; Whitaker, Leslie R.; Richie, Christopher T.; Zhang, Yajun J.; Campbell, Erin J.; Koivula, Pyry P.; Necarsulmer, Julie C.; Mejias-Aponte, Carlos; Morales, Marisela; Pickel, James; Smith, Jeffrey C.; Niv, Yael; Shaham, Yavin; Harvey, Brandon K.; Schoenbaum, Geoffrey Share Save
Share Save
Neurons Internalize Functionalized Micron-Sized Silicon Dioxide Microspheres Wallace, Veronica J.; Cimbro, Raffaello; Rubio, F. Javier; Fortuno, Lowella V.; Necarsulmer, Julie C.; Koivula, Pyry P.; Henderson, Mark J.; DeBiase, Lindsay M.; Warren, Brandon L.; Harvey, Brandon K.; Hope, Bruce T. Share Save
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