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SaveMachine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer
Xu, Qingyu; Ma, Ling; Streuer, Alexander; Altrock, Eva; Schmitt, Nanni; Rapp, Felicitas; Klaer, Alessa; Nowak, Verena; Oblaender, Julia; Weimer, Nadine; Palme, Iris; Goel, Melda; Zhu, Hong-hu; Hofmann, Wolf-Karsten; Nowak, Daniel; Riabov, Vladimir Share Save Primary Hematopoietic Cells of Vexas Patients Are Highly Sensitive to Treatment with TAK-243 and PevonedistatDemmerle, Marie; Klaer, Alessa; Streuer, Alexander; Riabov, Vladimir; Altrock, Eva; Rapp, Felicitas; Belzer, Ann-Christin; Klink, Teresa; Hahn, Meret; Hofmann, Franziska; Nowak, Verena; Weimer, Nadine; Oblaender, Julia; Palme, Iris; Goel, Melda; Darwich, Ali; Abba, Mohammed; Metzgeroth, Georgia; Hofmann, Wolf-Karsten; Nowak, Daniel; Schmitt, Nanni Share Save Share Save Titanium induces proinflammatory and tissue-destructive responses in primary human macrophagesGudima, Alexandru; Hesselbarth, David; Li, Guanhao; Riabov, Vladimir; Michel, Julia; Liu, Quan; Schmuttermaier, Christina; Jiao, Zhen; Sticht, Carsten; Jawhar, Ahmed; Obertacke, Udo; Klueter, Harald; Vrana, Nihal Engin; Kzhyshkowska, Julia Share Save Treatment with the apoptosis inhibitor Asunercept reduces clone sizes in patients with lower risk Myelodysplastic NeoplasmsStreuer, Alexander; Jann, Johann-Christoph; Boch, Tobias; Mossner, Maximilian; Riabov, Vladimir; Schmitt, Nanni; Altrock, Eva; Xu, Qingyu; Demmerle, Marie; Nowak, Verena; Oblaender, Julia; Palme, Iris; Weimer, Nadine; Rapp, Felicitas; Metzgeroth, Georgia; Hecht, Anna; Hoeger, Thomas; Merz, Christian; Hofmann, Wolf-Karsten; Nolte, Florian; Nowak, Daniel Share Save ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasmsRiabov, Vladimir; Xu, Qingyu; Schmitt, Nanni; Streuer, Alexander; Ge, Guo; Bolanos, Lyndsey; Wunderlich, Mark; Jann, Johann-Christoph; Wein, Alina; Altrock, Eva; Demmerle, Marie; Mukherjee, Sanjay; Ali, Abdullah Mahmood; Rapp, Felicitas; Nowak, Verena; Weimer, Nadine; Oblaender, Julia; Palme, Iris; Goel, Melda; Jawhar, Ahmed; Darwich, Ali; Wuchter, Patrick; Weiss, Christel; Raza, Azra; Foulks, Jason M.; Starczynowski, Daniel T.; Yang, Feng-Chun; Metzgeroth, Georgia; Steiner, Laurenz; Jawhar, Mohamad; Hofmann, Wolf-Karsten; Nowak, Daniel Share Save Significant improvement of bone marrow-derived MSC expansion from MDS patients by defined xeno-free mediumAltrock, Eva; Sens-Albert, Carla; Hofmann, Franziska; Riabov, Vladimir; Schmitt, Nanni; Xu, Qingyu; Jann, Johann-Christoph; Rapp, Felicitas; Steiner, Laurenz; Streuer, Alexander; Nowak, Verena; Oblaender, Julia; Weimer, Nadine; Palme, Iris; Goel, Melda; Darwich, Ali; Wuchter, Patrick; Metzgeroth, Georgia; Jawhar, Mohamad; Hofmann, Wolf-Karsten; Nowak, Daniel Share Save A Novel GGA-Binding Site Is Required for Intracellular Sorting Mediated by Stabilin-1Zhang, Jingjing; Gratchev, Alexei; Riabov, Vladimir; Mamidi, Srinivas; Schmuttermaier, Christina; Krusell, Liis; Kremmer, Elisabeth; Workman, Gail; Sage, E. Helene; Jalkanen, Sirpa; Goerdt, Sergij; Kzhyshkowska, Julia Share Save Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignanciesXu, Qingyu; Streuer, Alexander; Jann, Johann-Christoph; Altrock, Eva; Schmitt, Nanni; Flach, Johanna; Sens-Albert, Carla; Rapp, Felicitas; Wolf, Julia; Nowak, Verena; Weimer, Nadine; Oblaender, Julia; Palme, Iris; Kuzina, Mariia; Jawhar, Ahmed; Darwich, Ali; Weis, Cleo-Aron; Marx, Alexander; Wuchter, Patrick; Costina, Victor; Jaeger, Evelyn; Sperk, Elena; Neumaier, Michael; Fabarius, Alice; Metzgeroth, Georgia; Nolte, Florian; Steiner, Laurenz; Levkin, Pavel A.; Jawhar, Mohamad; Hofmann, Wolf-Karsten; Riabov, Vladimir; Nowak, Daniel Share Save Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGFLarionova, Irina; Kiselev, Artem; Kazakova, Elena; Liu, Tengfei; Patysheva, Marina; Iamshchikov, Pavel; Liu, Quan; Mossel, Dieuwertje M.; Riabov, Vladimir; Rakina, Militsa; Sergushichev, Alexey; Bezgodova, Natalia; Vtorushin, Sergei; Litviakov, Nikolai; Denisov, Evgeny; Koshkin, Philipp; Pyankov, Denis; Tsyganov, Matvei; Ibragimova, Marina; Cherdyntseva, Nadezhda; Kzhyshkowska, Julia Share Save Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivoJann, Johann-Christoph; Mossner, Maximilian; Riabov, Vladimir; Altrock, Eva; Schmitt, Nanni; Flach, Johanna; Xu, Qingyu; Nowak, Verena; Oblaender, Julia; Palme, Iris; Weimer, Nadine; Streuer, Alexander; Jawhar, Ahmed; Darwich, Ali; Jawhar, Mohammad; Metzgeroth, Georgia; Nolte, Florian; Hofmann, Wolf-Karsten; Nowak, Daniel Share Save Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromesSchmitt, Nanni; Jann, Johann-Christoph; Altrock, Eva; Flach, Johanna; Danner, Justine; Uhlig, Stefanie; Streuer, Alexander; Knaflic, Antje; Riabov, Vladimir; Xu, Qingyu; Mehralivand, Arwin; Palme, Iris; Nowak, Verena; Oblaender, Julia; Weimer, Nadine; Haselmann, Verena; Jawhar, Ahmed; Darwich, Ali; Weis, Cleo-Aron; Marx, Alexander; Steiner, Laurenz; Jawhar, Mohamad; Metzgeroth, Georgia; Boch, Tobias; Nolte, Florian; Hofmann, Wolf-Karsten; Nowak, Daniel Share Save Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutationsFlach, Johanna; Jann, Johann-Christoph; Knaflic, Antje; Riabov, Vladimir; Streuer, Alexander; Altrock, Eva; Xu, Qingyu; Schmitt, Nanni; Oblander, Julia; Nowak, Verena; Danner, Justine; Mehralivand, Arwin; Hofmann, Franziska; Palme, Iris; Jawhar, Ahmed; Wuchter, Patrick; Metzgeroth, Georgia; Nolte, Florian; Hofmann, Wolf-Karsten; Nowak, Daniel Share Save Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic ConditionsMossel, Dieuwertje M.; Moganti, Kondaiah; Riabov, Vladimir; Weiss, Christel; Kopf, Stefan; Cordero, Julio; Dobreva, Gergana; Rots, Marianne G.; Klueter, Harald; Harmsen, Martin C.; Kzhyshkowska, Julia Share Save SI-CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor-associated macrophagesYin, Shuiping; Wang, Nan; Riabov, Vladimir; Mossel, Dieuwertje M.; Larionova, Irina; Schledzewski, Kai; Trofimova, Olga; Sevastyanova, Tatyana; Zajakina, Anna; Schmuttermaier, Christina; Gratchev, Alexei; Flatley, Andrew; Kremmer, Elisabeth; Zavyalova, Marina; Cherdyntseva, Nadezhda; Simon-Keller, Katja; Marx, Alexander; Klueter, Harald; Goerdt, Sergij; Kzhyshkowska, Julia Share Save Tumor-associated macrophages in human breast cancer produce new monocyte attracting and pro-angiogenic factor YKL-39 indicative for increased metastasis after neoadjuvant chemotherapyLiu, Tengfei; Larionova, Irina; Litviakov, Nikolay; Riabov, Vladimir; Zavyalova, Marina; Tsyganov, Matvey; Buldakov, Mikhail; Song, Bin; Moganti, Kondaiah; Kazantseva, Polina; Slonimskaya, Elena; Kremmer, Elisabeth; Flatley, Andrew; Klueter, Harald; Cherdyntseva, Nadezhda; Kzhyshkowska, Julia Share Save IL-4 driven transcription factor FoxQ1 is expressed by monocytes in atopic dermatitis and stimulates monocyte migrationOvsiy, Ilja; Riabov, Vladimir; Manousaridis, Ioannis; Michel, Julia; Moganti, Kondaiah; Yin, Shuiping; Liu, Tengfei; Sticht, Carsten; Kremmer, Elisabeth; Harmsen, Martin C.; Goerdt, Sergij; Gratchev, Alexei; Kzhyshkowska, Julia Share Save Atmospheric pressure plasma assisted immobilization of hyaluronic acid on tissue engineering PLA-based scaffolds and its effect on primary human macrophagesKudryavtseva, Valeriya; Stankevich, Ksenia; Gudima, Alexandu; Kibler, Elina; Zhukov, Yuri; Bolbasov, Evgeniy; Malashicheva, Anna; Zhuravlev, Mikhail; Riabov, Vladimir; Liu, Tengfei; Filimonov, Victor; Remnev, Gennady; Klueter, Harald; Kzhyshkowska, Julia; Tverdokhlebov, Sergei Share Save Generation of anti-inflammatory macrophages for implants and regenerative medicine using self-standing release systems with a phenotype-fixing cytokine cocktail formulationRiabov, Vladimir; Salazar, Fabian; Htwe, Su Su; Gudima, Alexandru; Schmuttermaier, Christina; Barthes, Julien; Knopf-Marques, Helena; Kluter, Harald; Ghaemmaghami, Amir M.; Vrana, Nihal Engin; Kzhyshkowska, Julia Share Save 
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