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Alan Brash

vanderbilt university
H-index:72
Citation Count:1.7万
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Unusual and atypical cyclooxygenase reactions
Journal of Biological Chemistry
IF3.9
2026-02-050
OAAI
Claus Schneider; Alan R. Brash
The effects of naturally occurring mutations on functionality of oxylipin metabolizing dehydrogenase reductase 9

自然发生的突变对氧脂素代谢脱氢还原酶9功能的影响

Journal of Biological Chemistry
IF3.9
2025-09-110
OAAI
Samuel E. Wirth; Svetlana Pakhomova; Olga V. Belyaeva; William E. Boeglin; Alan R. Brash; Marcia E. Newcomer; Natalia Y. Kedishvili; Kirill M. Popov
The origin of hydroxy-cyclohexenone fatty acids from skin barrier protein and relevance to covalent binding of ceramides

羟基-环己烯酮脂肪酸的来源与皮肤屏障蛋白的关系及其与鞘脂共价结合的相关性

Journal of Lipid Research
IF4.1
2025-06-140
OA
Saori Noguchi; William E. Boeglin; Fumie Nakashima; Donald F. Stec; M. Wade Calcutt; Takuya Takeichi; Masashi Akiyama; Alan R. Brash
Heme-catalyzed degradation of linoleate 9-hydroperoxide (9-HPODE) forms two allylic epoxy-ketones via a proposed pseudo-symmetrical diepoxy radical intermediate
FREE RADICAL RESEARCH
IF2.9
2024-08-040
OA
Noguchi, Saori; Boeglin, William E.; Porter, Ned A.; Brash, Alan R.
Fatty acids of Helicobacter pylori lipoproteins CagT and Lpp20
MICROBIOLOGY SPECTRUM
IF3.8
2024-05-021
OAAI
Mcclain, Mark S.; Boeglin, William E.; Algood, Holly M. Scott; Brash, Alan R.
The Michael addition of thiols to 13-oxo-octadecadienoate (13-oxo-ODE) with implications for LC-MS analysis of glutathione conjugation
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2024-05-010
OAAI
Boeglin, William E.; Stec, Donald F.; Noguchi, Saori; Calcutt, M. Wade; Brash, Alan R.
Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

未能将标准的检测极限或定量极限标准应用于专门的解析介质分析，错误地表征了它们在生物样品中的存在

NATURE COMMUNICATIONS
IF15.7
2023-11-0914
OAAI
O'Donnell, Valerie B.; Schebb, Nils H.; Milne, Ginger L.; Murphy, Michael P.; Thomas, Christopher P.; Steinhilber, Dieter; Gelhaus, Stacy L.; Kuehn, Hartmut; Gelb, Michael H.; Jakobsson, Per-Johan; Blair, Ian A.; Murphy, Robert C.; Freeman, Bruce A.; Brash, Alan R.; Fitzgerald, Garret A.
Evaluation of.-alkynyl-labeled linoleic and arachidonic acids as substrates for recombinant lipoxygenase pathway enzymes

评估。-炔基标记的亚油酸和花生四烯酸作为重组脂氧合酶途径酶的底物

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
IF3.3
2023-09-011
OAAI
Noguchi, Saori; Tallman, Keri A.; Porter, Ned A.; Calcutt, M. Wade; Boeglin, William E.; Brash, Alan R.
Two C18 hydroxy-cyclohexenone fatty acids from mammalian epidermis: Potential relation to 12R-lipoxygenase and covalent binding of ceramides (vol 299, 104739, 2023)
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2023-06-011
OAAI
Brash, Alan R.; Noguchi, Saori; Boeglin, William E.; Calcutt, M. Wade; Stec, Donald F.; Schneider, Claus; Meyer, Jason M.
Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid
JOURNAL OF LIPID RESEARCH
IF4.1
2023-06-011
OAAI
Meyer, Jason M.; Boeglin, William E.; Brash, Alan R.
Dehydrogenase reductase 9 (SDR9C4) and related homologs recognize a broad spectrum of lipid mediator oxylipins as substrates
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2022-01-014
OAAI
Belyaeva, Olga, V; Wirth, Samuel E.; Boeglin, William E.; Karki, Suman; Goggans, Kelli R.; Wendell, Stacy G.; Popov, Kirill M.; Brash, Alan R.; Kedishvili, Natalia Y.
Monolayer autoxidation of arachidonic acid to epoxyeicosatrienoic acids as a model of their potential formation in cell membranes
JOURNAL OF LIPID RESEARCH
IF4.1
2022-01-014
OAAI
Weiny, James A.; Boeglin, William E.; Calcutt, M. Wade; Stec, Donald F.; Brash, Alan R.
Analysis of 12/15-lipoxygenase metabolism of EPA and DHA with special attention to authentication of docosatrienes
JOURNAL OF LIPID RESEARCH
IF4.1
2021-01-0111
OAAI
Jin, Jing; Boeglin, William E.; Brash, Alan R.
Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2021-01-0118
OAAI
Edin, Matthew L.; Yamanashi, Haruto; Boeglin, William E.; Graves, Joan P.; DeGraff, Laura M.; Lih, Fred B.; Zeldin, Darryl C.; Brash, Alan R.
Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions

人类银屑病病变中亚油酰基-ω-羟基神经酰胺生物合成途径的脂质组学和转录分析

JOURNAL OF LIPID RESEARCH
IF4.1
2021-01-0125
OAAI
Tyrrell, Victoria J.; Ali, Faraz; Boeglin, William E.; Andrews, Robert; Burston, James; Birchall, James C.; Ingram, John R.; Murphy, Robert C.; Piguet, Vincent; Brash, Alan R.; O'Donnell, Valerie B.; Thomas, Christopher P.
SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-01-1361
OA
Takeichi, Takuya; Hirabayashi, Tetsuya; Miyasaka, Yuki; Kawamoto, Akane; Okuno, Yusuke; Taguchi, Shijima; Tanahashi, Kana; Murase, Chiaki; Takama, Hiroyuki; Tanaka, Kosei; Boeglin, William E.; Calcutt, M. Wade; Watanabe, Daisuke; Kono, Michihiro; Muro, Yoshinao; Ishikawa, Junko; Ohno, Tamio; Brash, Alan R.; Akiyama, Masashi
Revising the structure of a new eicosanoid from human platelets to 8,9-11,12-diepoxy-13-hydroxyeicosadienoic acid
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2019-06-013
OAAI
Kornilov, Andrei; Kennedy, Paul D.; Aldrovandi, Maceler; Watson, Andrew J. A.; Hinz, Christine; Harless, Bryan; Colombo, Joseph; Maxey, Kirk M.; Tyrrell, Victoria J.; Simon, Matthew; Aggarwal, Varinder K.; Boeglin, William E.; Brash, Alan R.; Murphy, Robert C.; O'Donnell, Valerie B.
Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope
JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2019-04-0141
OAAI
Crumrine, Debra; Khnykin, Denis; Krieg, Peter; Man, Mao-Qiang; Celli, Anna; Mauro, Theodora M.; Wakefield, Joan S.; Menon, Gopinathan; Mauldin, Elizabeth; Miner, Jeffrey H.; Lin, Meei-Hua; Brash, Alan R.; Sprecher, Eli; Radner, Franz P. W.; Choate, Keith; Roop, Dennis; Uchida, Yoshikazu; Gruber, Robert; Schmuth, Matthias; Elias, Peter M.
Origin and functions of the corneocyte lipid envelope
JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2018-05-010
OAAI
Crumrine, D.; Khnykin, D.; Krieg, P.; Man, M.; Celli, A.; Mauro, T.; Menon, G.; Mauldin, E.; Miner, J.; Brash, A.; Sprecher, E.; Radner, F.; Choate, K.; Roop, D. R.; Uchida, Y.; Gruber, R.; Schmuth, M.; Elias, P.
Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

具有与皮肤屏障功能相关的顺式和反式脂肪酸环氧化物的哺乳动物环氧化物水解酶的催化活性

JOURNAL OF LIPID RESEARCH
IF4.1
2018-04-0127
OAAI
Yamanashi, Haruto; Boeglin, William E.; Morisseau, Christophe; Davis, Robert W.; Sulikowski, Gary A.; Hammock, Bruce D.; Brash, Alan R.

Research Directions

The data has not been retrieved yet.
W
William E. Boeglin
H-index:40Papers:166Citations:5,139
C
Claus Schneider
H-index:62Papers:302Citations:1.2万
郑玉祥 cover
郑玉祥
H-index:33Papers:285Citations:5,056
D
Donald F. Stec
H-index:25Papers:80Citations:1,684
N
Ned A. Porter
H-index:72Papers:490Citations:2.1万
M
M. Wade Calcutt
H-index:30Papers:86Citations:2,516
S
Saori Noguchi
H-index:2Papers:6Citations:12
C
Christopher P. Thomas
H-index:22Papers:53Citations:1,690
V
Valerie B. O’Donnell
H-index:69Papers:235Citations:2.6万
M
Masashi Akiyama
H-index:79Papers:1,038Citations:2.4万