Not logged inBET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Kim, Dae-Hwan; Sun, Duanchen; Storck, William K.; Leng, Katherine Welker; Jenkins, Chelsea; Coleman, Daniel J.; Sampson, David; Guan, Xiangnan; Kumaraswamy, Anbarasu; Rodansky, Eva S.; Urrutia, Joshua A.; Schwartzman, Jacob A.; Zhang, Chao; Beltran, Himisha; Labrecque, Mark P.; Morrissey, Colm; Lucas, Jared M.; Coleman, Ilsa M.; Nelson, Peter S.; Corey, Eva; Handelman, Samuel K.; Sexton, Jonathan Z.; Aggarwal, Rahul; Abida, Wassim; Feng, Felix Y.; Small, Eric J.; Spratt, Daniel E.; Bankhead, Armand, III; Rao, Arvind; Gesner, Emily M.; Attwell, Sarah; Lakhotia, Sanjay; Campeau, Eric; Yates, Joel A.; Xia, Zheng; Alumkal, Joshi J. .png)
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SaveA Phase Ib/IIa Study of the Pan-BET Inhibitor ZEN-3694 in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate CancerAggarwal, Rahul R.; Schweizer, Michael T.; Nanus, David M.; Pantuck, Allan J.; Heath, Elisabeth, I; Campeau, Eric; Attwell, Sarah; Norek, Karen; Snyder, Margo; Bauman, Lisa; Lakhotia, Sanjay; Feng, Felix Y.; Small, Eric J.; Abida, Wassim; Alumkal, Joshi J. Share Save Overcoming resistance to inhibitors of CDK4/6 and BET in estrogen receptor-positive breast cancerCosin, Marc; Tian, Tian; Oliveros, Winona; Kharenko, Olesya A.; van der Horst, Edward H.; Patel, Reena G.; Calosing, Cyrus; Campeau, Eric; Jahagirdar, Ravi; Lakhotia, Sanjay; Mele, Marta; Palafox, Marta; Arribas, Joaquin; Oliveira, Mafalda; Saura, Cristina; Serra, Violeta; Peiro, Sandra Share Save A Phase Ib/IIa study of the BET bromodomain inhibitor ZEN-3694 in combination with enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC)Aggarwal, Rahul; Abida, Wassim; Schweizer, Michael; Pantuck, Allan; Nanus, David; Heath, Elisabeth; Lakhotia, Sanjay; Hansen, Henrik; Silverman, Michael; Bauman, Lisa; Snyder, Margo; Campeau, Eric; Norek, Karen; Attwell, Sarah; O'Farrell, Marie; Smith, Steve; Wegge, Philip; Jahagirdar, Ravi; Alumkal, Joshi Share Save Modulating BET Bromodomain Inhibitor ZEN-3694 and Enzalutamide Combination Dosing in a Metastatic Prostate Cancer Patient Using CURATE.AI, an Artificial Intelligence PlatformPantuck, Allan J.; Lee, Dong-Keun; Kee, Theodore; Wang, Peter; Lakhotia, Sanjay; Silverman, Michael H.; Mathis, Colleen; Drakaki, Alexandra; Belldegrun, Arie S.; Ho, Chih-Ming; Ho, Dean Share Save Preclinical development and clinical validation of a whole blood pharmacodynamic marker assay for the BET bromodomain inhibitor ZEN-3694 in metastatic castration-resistant prostate cancer (mCRPC) patientsTsujikawa, Laura; Norek, Karen; Calosing, Cyrus; Attwell, Sarah; Gilham, Dean; Sharma, Nimisha; Tobin, Jennifer; Haager, Michelle; Jahagirdar, Ravi; Lakhotia, Sanjay; Hansen, Henrik C.; Campeau, Eric Share Save Share Save Preclinical characterization of ZEN-3694, a novel BET bromodomain inhibitor entering phase I studies for metastatic castration-resistant prostate cancer (mCRPC)Attwell, Sarah; Jahagirdar, Ravi; Norek, Karen; Calosing, Cyrus; Tsujikawa, Laura; Kharenko, Olesya A.; Patel, Reena G.; Gesner, Emily M.; Corey, Eva; Nguyen, Holly M.; Lakhotia, Sanjay; Hansen, Henrik C.; Campeau, Eric Share Save 
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