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Preclinical characterization of the anti-PD-L1 monoclonal antibody LY3300054 Carpenito, Carmine; Li, Yiwen; Wang, George X.; Malabunga, Maria S.; Haidar, Jaafar N.; Forest, Amelie; Murphy, Mary Y.; Hall, Gerald E.; Wang, Cindy; Shen, Leyi; Sonyi, Andreas; Chin, Darin; Pennello, Anthony L.; Inigo, Ivan V.; Surguladze, David; Yao, Yung-mae; Burtrum, Douglas; Novosiadly, Ruslan D.; Persaud, Kris; Ludwig, Dale L.; Kalos, Michael D. Share Save
Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade Holmgaard, Rikke B.; Schaer, David A.; Li, Yanxia; Castaneda, Stephen P.; Murphy, Mary Y.; Xu, Xiaohong; Inigo, Ivan; Dobkin, Julie; Manro, Jason R.; Iversen, Philip W.; Surguladze, David; Hall, Gerald E.; Novosiadly, Ruslan D.; Benhadji, Karim A.; Plowman, Gregory D.; Kalos, Michael; Driscoll, Kyla E. Share Save
Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 (vol 6, 31, 2018) Li, Yiwen; Carpenito, Carmine; Wang, George; Surguladze, David; Forest, Amelie; Malabunga, Maria; Murphy, Mary; Zhang, Yiwei; Sonyi, Andreas; Chin, Darin; Burtrum, Douglas; Inigo, Ivan; Pennello, Anthony; Shen, Leyi; Malherbe, Laurent; Chen, Xinlei; Hall, Gerald; Haidar, Jaafar N.; Ludwig, Dale L.; Novosiadly, Ruslan D.; Kalos, Michael Share Save
Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 Li, Yiwen; Carpenito, Carmine; Wang, George; Surguladze, David; Forest, Amelie; Malabunga, Maria; Murphy, Mary; Zhang, Yiwei; Sonyi, Andreas; Chin, Darin; Burtrum, Douglas; Inigo, Ivan; Pennello, Anthony; Shen, Leyi; Malherbe, Laurent; Chen, Xinlei; Hall, Gerald; Haidar, Jaafar N.; Ludwig, Dale L.; Novosiadly, Ruslan D.; Kalos, Michael Share Save
Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy Holmgaard, Rikke B.; Brachfeld, Alexandra; Gasmi, Billel; Jones, David R.; Mattar, Marissa; Doman, Thompson; Murphy, Mary; Schaer, David; Wolchok, Jedd D.; Merghoub, Taha Share Save
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