Not logged inIntegrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function
Barden, Markus; Elsenbroich, Patrick Ronan; Haas, Vivian; Ertelt, Moritz; Pervan, Philip; Velas, Lukas; Gergely, Bence; Szoeor, Arpad; Harrer, Dennis Christoph; Bezler, Valerie; Holzinger, Astrid; Friis, Rasmus Ulslev Wegener; Vereb, Gyorgy; Schuetz, Gerhard J.; Schoeder, Clara T.; Hombach, Andreas A.; Abken, Hinrich .png)
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SaveCAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activationBarden, Markus; Holzinger, Astrid; Velas, Lukas; Mezosi-Csaplar, Marianna; Szoeor, Arpad; Vereb, Gyoergy; Schuetz, Gerhard J.; Hombach, Andreas A.; Abken, Hinrich Share Save Share Save Share Save 
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