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R

Rutilio H. Clark

just-evotec biologics

10H-index
24Paper Count
539Citation Count
Published Papers 8
Publication Date
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A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV
errStructure
IF4.3
err2025-05-14
err0
errOAAI
errMohammad M. Sajadi; Abdolrahim Abbasi; Zahra Rikhtegaran Tehrani; Christine Siska; Rutilio Clark; Woo Chi; Michael S. Seaman; Dieter Mielke; Kshitij Wagh; Qingbo Liu; Taylor Jumpa; Randal R. Ketchem; Dung N. Nguyen; William D. Tolbert; Brian G. Pierce; Ben Atkinson; Derrick Deming; Megan Sprague; Andrew Asakawa; David Ferrer; Yasmin Dunn; Sarah Calvillo; Rui Yin; Johnathan D. Guest; Bette Korber; Bryan T. Mayer; Alicia H. Sato; Xin Ouyang; Scott Foulke; Parham Habibzadeh; Maryam Karimi; Arash Aslanabadi; Mahsa Hojabri; Saman Saadat; Roza Zareidoodeji; Mateusz Kędzior; Edwin Pozharski; Alonso Heredia; Hegang Chen; David Montefiori; Guido Ferrari; Marzena Pazgier; George K. Lewis; Joseph G. Jardine; Paolo Lusso; Anthony DeVico
errShare
errSave
Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2020-01-01
err11
errOAAI
errKerwin, Bruce A.; Bennett, Chelsey; Brodsky, Yan; Clark, Rutilio; Floyd, J. Alaina; Gillespie, Alison; Mayer, Bryan T.; McClure, Megan; Siska, Christine; Seaman, Michael S.; Seaton, Kelly E.; Shaver, Jeremy; Tomaras, Georgia D.; Yates, Nicole L.; Ketchem, Randal R.
errShare
errSave
CHO cell production and sequence improvement in the 13C6FR1 anti-Ebola antibody
errMABS
IF7.3
err2016-01-13
err14
errOAAI
errPettit, Dean K.; Rogers, Richard S.; Arthur, Kelly; Brodsky, Yan; Clark, Rutilio H.; Crowell, Chris; Ennis, Jane; Gillespie, Alison; Gillespie, Ron; Livingston, Brittney; Nalbandian, Edith; Pace, Danielle; Smidt, Pauline; Pauly, Michael; Timmons, Ken; Trentalange, Michael; Whaley, Kevin J.; Zeitlin, Larry; Thomas, James N.
errShare
errSave
A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-03-01
err103
errOAAI
errLiu, Zhi; Leng, Esther C.; Gunasekaran, Kannan; Pentony, Martin; Shen, Min; Howard, Monique; Stoops, Janelle; Manchulenko, Kathy; Razinkov, Vladimir; Liu, Hua; Fanslow, William; Hu, Zhonghua; Sun, Nancy; Hasegawa, Haruki; Clark, Rutilio; Foltz, Ian N.; Yan, Wei
errShare
errSave
Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs
errMABS
IF7.3
err2014-11-03
err17
errOAAI
errClark, Rutilio H.; Latypov, Ramil F.; De Imus, Cyr; Carter, Jane; Wilson, Zien; Manchulenko, Kathy; Brown, Michael E.; Ketchem, Randal R.
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errSave
Protein electrostatic surface distribution can determine whether calcium oxalate crystal growth is promoted or inhibited
errCALCIFIED TISSUE INTERNATIONAL
IF3.2
err2014-03-17
err35
PREAI
errClark, RH; Campbell, AA; Klumb, LA; Long, CJ; Stayton, PS
errShare
errSave
Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2004-01-20
err111
errOAAI
errSchief, WR; Clark, RH; Crevenna, AH; Howard, J
errShare
errSave
A peptide that inhibits hydroxyapatite growth is in an extended conformation on the crystal surface
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err1998-10-13
err114
errOAAI
errLong, JR; Dindot, JL; Zebroski, H; Kiihne, S; Clark, RH; Campbell, AA; Stayton, PS; Drobny, GP
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
D
David C. Montefiori
H-index: 142 · Papers: 1.2K
B
Bette Korber
H-index: 131 · Papers: 518
M
Michael S. Seaman
H-index: 104 · Papers: 424
J
Jonathon Howard
H-index: 91 · Papers: 381
G
Georgia D. Tomaras
H-index: 87 · Papers: 533
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