Edwin K. Silverman - Publications, H-index & Citations

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Edwin K. Silverman

Brigham and Women's Hospital

134H-index

1.1KPaper Count

6.9WCitation Count

Published Papers 406

Publication Date

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed

Science

IF45.8

2026-07-16

PREAI

Peter Orchard; Thomas W. Blackwell; Linda Kachuri; Peter J. Castaldi; Michael H. Cho; Stephanie A. Christenson; Peter Durda; Stacey Gabriel; Craig P. Hersh; Scott Huntsman; Seungyong Hwang; Roby Joehanes; Mari Johnson; Xingnan Li; Honghuang Lin; Ching-Ti Liu; Yongmei Liu; Angel C. Y. Mak; Ani W. Manichaikul; David T. Paik; Aabida Saferali; Joshua D. Smith; Kent D. Taylor; Russell P. Tracy; Jiongming Wang; Mingqiang Wang; Joshua S. Weinstock; Jeffrey Weiss; Heather E. Wheeler; Ying Zhou; Sebastian Zöllner; Joseph C. Wu; Luisa Mestroni; Sharon Graw; Matthew R. G. Taylor; Victor E. Ortega; W. Craig Johnson; Weiniu Gan; Goncalo Abecasis; Deborah A. Nickerson; Namrata Gupta; Kristin Ardlie; Prescott G. Woodruff; Russell P. Bowler; Deborah A. Meyers; Alex Reiner; Charles Kooperberg; Elad Ziv; Ramachandran S. Vasan; Martin G. Larson; L. Adrienne Cupples; Edwin K. Silverman; Stephen S. Rich; Nancy Heard-Costa; Hua Tang; Jerome I. Rotter; Albert V. Smith; Daniel Levy; ; ; François Aguet; Laura J. Scott; Laura M. Raffield; Stephen C. J. Parker

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Nasal epithelium and blood transcriptomic signatures associations with smoking and exacerbations

European Respiratory Journal

IF21

2026-02-01

PREAI

Tejwani, Vickram; Sarkar, Arunangshu; Guo, Claire J.; Sajuthi, Satria; Castaldi, Peter; Alexander, Laura E. Crotty; Barjaktarevic, Igor Z.; Comellas, Alejandro P.; Dawson, Jennifer; Demeo, Dawn L.; Hersh, Craig P.; Ruvuna, Lisa; Sharma, Sunita; Silverman, Edwin K.; Pratte, Katherine A.; Seibold, Max; Kechris, Katerina; Bowler, Russell P.

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Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program

american journal of human genetics

IF0

2025-09-18

PREAI

Nannan Wang; Franklin P. Ockerman; Laura Y. Zhou; Megan L. Grove; Taryn Alkis; John Barnard; Russell P. Bowler; Clary B. Clish; Shinhye Chung; Emily Drzymalla; Anne M. Evans; Nora Franceschini; Robert E. Gerszten; Madeline G. Gillman; Scott R. Hutton; Rachel S. Kelly; Charles Kooperberg; Martin G. Larson; Jessica Lasky-Su; Deborah A. Meyers; Prescott G. Woodruff; Alexander P. Reiner; Stephen S. Rich; Jerome I. Rotter; Edwin K. Silverman; Ramachandran S. Vasan; Scott T. Weiss; Kari E. Wong; Alexis C. Wood; Lang Wu; Ronit Yarden; Thomas W. Blackwell; Albert V. Smith; Han Chen; Laura M. Raffield; Bing Yu

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How exposomic tools complement and enrich genomic research

Cell Genomics

IF9

2025-07-24

OAAI

Konstantinos C. Makris; Andrea Baccarelli; Edwin K. Silverman; Robert O. Wright

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Proteomic biomarkers of emphysema-predominant and non-emphysema-predominant chronic obstructive pulmonary disease

eBioMedicine

IF10.8

2025-06-12

OAAI

Yu-Hang Zhang; Peter J. Castaldi; Russell P. Bowler; Katherine A. Pratte; Gregory L. Kinney; Kendra A. Young; Heena Rijhwani; Sharon M. Lutz; Craig P. Hersh; Michael H. Cho; Jarrett D. Morrow; Edwin K. Silverman

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B-cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-05-02

OAAI

Moll, Matthew; Xu, Zhonghui; Boueiz, Adel; Ryu, Min Hyung; Silverman, Edwin K.; Cho, Michael H.; Hersh, Craig P.; Sauler, Maor; Polverino, Francesca; Kinney, Gregory L.; Curtis, Jeffrey L.; Crotty-Alexander, Laura E.; Vollmers, Christopher; Castaldi, Peter J.

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Identifying chronic obstructive pulmonary disease subtypes using multi-trait genetics

EBIOMEDICINE

IF10.8

2025-03-01

PREAI

Ziyatdinov, Andrey; Hobbs, Brian D.; Kanaan-Izquierdo, Samir; Moll, Matthew; Sakornsakolpat, Phuwanat; Shrine, Nick; Chen, Jing; Song, Kijoung; Bowler, Russell P.; Castaldi, Peter J.; Tobin, Martin D.; Kraft, Peter; Silverman, Edwin K.; Julienne, Hanna; Cho, Michael H.; Aschard, Hugues

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HHIP protein interactions in lung cells provide insight into COPD pathogenesis

HUMAN MOLECULAR GENETICS

IF3.2

2025-02-13

PREAI

Deritei, David; Inuzuka, Hiroyuki; Castaldi, Peter J.; Yun, Jeong Hyun; Xu, Zhonghui; Anamika, Wardatul Jannat; Asara, John M.; Guo, Feng; Zhou, Xiaobo; Glass, Kimberly; Wei, Wenyi; Silverman, Edwin K.

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The Association of Interstitial Lung Abnormalities and Preserved Ratio Impaired Spirometry With Mortality

CHEST

IF8.6

2025-02-11

PREAI

Sean Kalra; Brian Hobbs; Gary M. Hunninghake; Aravind A. Menon; Rachel Putman; Claire Cutting; Hiroto Hatabu; Edwin K. Silverman; Emily Wan; Michael H. Cho; Matthew Moll

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Sex-Biased Regulation of Extracellular Matrix Genes in Chronic Obstructive Pulmonary Disease

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2025-01-01

PREAI

Lopes-Ramos, Camila M.; Shutta, Katherine H.; Ryu, Min Hyung; Huang, Yichen; Saha, Enakshi; Ziniti, John; Chase, Robert; Hobbs, Brian D.; Yun, Jeong H.; Castaldi, Peter; Hersh, Craig P.; Glass, Kimberly; Silverman, Edwin K.; Quackenbush, John; Demeo, Dawn L.

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Computational deconvolution of cell type-specific gene expression in COPD and IPF lungs reveals disease severity associations

BMC GENOMICS

IF3.7

2024-12-18

OAAI

Ryu, Min Hyung; Yun, Jeong H.; Kim, Kangjin; Gentili, Michele; Ghosh, Auyon; Sciurba, Frank; Barwick, Lucas; Limper, Andrew; Criner, Gerard; Brown, Kevin K.; Wise, Robert; Martinez, Fernando J.; Flaherty, Kevin R.; Cho, Michael H.; Castaldi, Peter J.; Demeo, Dawn L.; Silverman, Edwin K.; Hersh, Craig P.; Morrow, Jarrett D.

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Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies

EBIOMEDICINE

IF10.8

2024-12-01

OAAI

Moll, Matthew; Hecker, Julian; Platig, John; Zhang, Jingzhou; Ghosh, Auyon J.; Pratte, Katherine A.; Wang, Rui-Sheng; Hill, Davin; Konigsberg, Iain R.; Chiles, Joe W.; Hersh, Craig P.; Castaldi, Peter J.; Glass, Kimberly; Dy, Jennifer G.; Sin, Don D.; Tal-Singer, Ruth; Mouded, Majd; Rennard, Stephen I.; Anderson, Gary P.; Kinney, Gregory L.; Bowler, Russell P.; Curtis, Jeffrey L.; Mcdonald, Merry-Lynn; Silverman, Edwin K.; Hobbs, Brian D.; Cho, Michael H.

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Lung transcriptomics of emphysema reveal barrier function impairment and macrophage M1-M2 imbalance

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

El Boueiz, Adel; Lu, Robin; Suryadevara, Rahul; Xu, Zhonghui; Jain, Dhawal; Curtis, Jeffrey; Sauler, Maor; Bartholmai, Brian; Silverman, Edwin; Castaldi, Peter

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Pathogenic variants of genes associated with pulmonary arterial hypertension (PAH): Insights from Trans-Omics for Precision Medicine (TOPMed) study participants

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Foris, Vasile; Boueiz, Adel; Kim, Kangjin; Tern, Courtney; Silverman, Edwin K.; Cho, Michael H.

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Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height

NATURE COMMUNICATIONS

IF15.7

2024-10-03

OAAI

Hawkes, Gareth; Beaumont, Robin N.; Li, Zilin; Mandla, Ravi; Li, Xihao; Albert, Christine M.; Arnett, Donna K.; Ashley-Koch, Allison E.; Ashrani, Aneel A.; Barnes, Kathleen C.; Boerwinkle, Eric; Brody, Jennifer A.; Carson, April P.; Chami, Nathalie; Chen, Yii-Der Ida; Chung, Mina K.; Curran, Joanne E.; Darbar, Dawood; Ellinor, Patrick T.; Fornage, Myrian; Gordeuk, Victor R.; Guo, Xiuqing; He, Jiang; Hwu, Chii-Min; Kalyani, Rita R.; Kaplan, Robert; Kardia, Sharon L. R.; Kooperberg, Charles; Loos, Ruth J. F.; Lubitz, Steven A.; Minster, Ryan L.; Naseri, Take; Viali, Satupa'itea; Mitchell, Braxton D.; Murabito, Joanne M.; Palmer, Nicholette D.; Psaty, Bruce M.; Redline, Susan; Shoemaker, M. Benjamin; Silverman, Edwin K.; Telen, Marilyn J.; Weiss, Scott T.; Yanek, Lisa R.; Zhou, Hufeng; Liu, Ching-Ti; North, Kari E.; Justice, Anne E.; Locke, Jonathan M.; Owens, Nick; Murray, Anna; Patel, Kashyap; Frayling, Timothy M.; Wright, Caroline F.; Wood, Andrew R.; Lin, Xihong; Manning, Alisa; Weedon, Michael N.

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INTERSTITIAL LUNG ABNORMALITIES AND CORONARY HEART DISEASE IN COPD GENE

CHEST

IF8.6

2024-10-01

PREAI

Cutting, Claire; Rose, Jonathan; Tukpah, AnnMarcia; Wada, Noriaki; Nishino, Mizuki; Moll, Matthew; Cho, Michael; Silverman, Edwin; Washko, George; Kinney, Gregory L.; Hokanson, John; Rossiter, Harry B.; Budoff, Matthew; Hatabu, Hiroto; Hunninghake, Gary M.; Putman, Rachel

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Genetically Predicted Body Mass Index and Mortality in Chronic Obstructive Pulmonary Disease

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2024-10-01

PREAI

Zhang, Jingzhou; Moll, Matthew; Hobbs, Brian D.; Bakke, Per; Regan, Elizabeth A.; Xu, Hanfei; Dupuis, Josee; Chiles, Joe W.; McDonald, Merry-Lynn N.; Divo, Miguel J.; Silverman, Edwin K.; Celli, Bartolome R.; O'Connor, George T.; Cho, Michael H.

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Chitinase 3-like-1 Inhibits Innate Antitumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPa- and CD24-Siglec10-Mediated Phagocytosis

JOURNAL OF IMMUNOLOGY

IF3.4

2024-09-18

PREAI

Ma, Bing; Kamle, Suchitra; Sadanaga, Takayuki; Lee, Chang-Min; Lee, Joyce H.; Yee, Daniel C.; Zhu, Zhou; Silverman, Edwin K.; Demeo, Dawn L.; Choi, Augustine M. K.; Lee, Chun Geun; Elias, Jack A.

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A protein risk score for all-cause and respiratory-specific mortality in non-Hispanic white and African American individuals who smoke

SCIENTIFIC REPORTS

IF3.9

2024-09-04

OAAI

Moll, Matthew; Pratte, Katherine A.; Debban, Catherine L.; Liu, Congjian; Belinsky, Steven A.; Picchi, Maria; Konigsberg, Iain; Tern, Courtney; Rijhwani, Heena; Hobbs, Brian D.; Silverman, Edwin K.; Tesfaigzi, Yohannes; Rich, Stephen S.; Manichaikul, Ani; Rotter, Jerome I.; Bowler, Russel P.; Cho, Michael H.

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Implications of Race Adjustment in Lung-Function Equations

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2024-06-13

OAAI

Diao, J. A.; He, Y.; Khazanchi, R.; Tiako, M. J. Nguemeni; Witonsky, J. I.; Pierson, E.; Rajpurkar, P.; Elhawary, J. R.; Melas-Kyriazi, L.; Yen, A.; Martin, A. R.; Levy, S.; Patel, C. J.; Farhat, M.; Borrell, L. N.; Cho, M. H.; Silverman, E. K.; Burchard, E. G.; Manrai, A. K.

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Research Directions