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C

Charles A. Specht

university of massachusetts system

66H-index
245Paper Count
1.2WCitation Count
Published Papers 57
Publication Date
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How post-translational modifications in pathogenic fungi inform pathogenesis and immune responses
errPLoS Pathogens
IF4.9
err2026-05-08
err1
errOAAI
errSahu, Satya Ranjan; Specht, Charles A.; Levitz, Stuart M.
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Vaccine-Mediated Protection of Mice Against African and Asian Clinical Strains of Cryptococcus neoformans
errJournal of Fungi 2025, Vol. 11, Page 886
IF4
err2025-12-16
err0
errOAAI
errDiana Carlson; Ruiying Wang; Zachary Hastings; Lorena V. N. Oliveira; Maureen M. Hester; Nicolle Rodriguez; Gabriel Kristian Pedersen; Jennifer L. Tenor; John R. Perfect; Charles A. Specht; Stuart M. Levitz
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Peripheral blood CD4+ and CD8+ T cell responses to Cryptococcus candidate vaccine antigens in human subjects with and without cryptococcosis
errJournal of Infection
IF11.9
err2025-05-29
err0
errOAAI
errLorena V.N. Oliveira; Jessica C. Hargarten; Ruiying Wang; Diana Carlson; Yoon-Dong Park; Charles A. Specht; Peter R. Williamson; Stuart M. Levitz
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Immunological correlates of protection mediated by a whole organism, Cryptococcus neoformans, vaccine deficient in chitosan
errMBIO
IF4.7
err2024-08-14
err5
errOAAI
errSpecht, Charles A.; Wang, Ruiying; Oliveira, Lorena V. N.; Hester, Maureen M.; Gomez, Christina; Mou, Zhongming; Carlson, Diana; Lee, Chrono K.; Hole, Camaron R.; Lam, Woei C.; Upadhya, Rajendra; Lodge, Jennifer K.; Levitz, Stuart M.
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Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines
errPLOS PATHOGENS
IF4.9
err2024-07-08
err3
errOAAI
errWang, Ruiying; Oliveira, Lorena V. N.; Hester, Maureen M.; Carlson, Diana; Christensen, Dennis; Specht, Charles A.; Levitz, Stuart M.
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errSave
Immune evasion by Cryptococcus gattii in vaccinated mice coinfected with C. neoformans
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-02-26
err3
errOAAI
errHester, Maureen M.; Carlson, Diana; Lodge, Jennifer K.; Levitz, Stuart M.; Specht, Charles A.
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Dysregulated pulmonary inflammatoryinflammatory responses exacerbate the outcome of secondary aspergillosis following
errMBIO
IF4.7
err2023-10-31
err5
errOAAI
errLee, Chrono K.; Oliveira, Lorena V. N.; Akalin, Ali; Specht, Charles A.; Lourenco, Diana; Gomez, Christina L.; Ramirez-Ortiz, Zaida G.; Wang, Jennifer P.; Levitz, Stuart M.
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errSave
One Step Purification-Vaccine Delivery System
errPHARMACEUTICS
IF5.5
err2023-05-01
err6
errOAAI
errSoto, Ernesto R. R.; Specht, Charles A. A.; Lee, Chrono K. K.; Levitz, Stuart M. M.; Ostroff, Gary R. R.
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errSave
Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases
errNPJ VACCINES
IF6.5
err2023-02-02
err10
errOAAI
errWang, Ruiying; Oliveira, Lorena V. N.; Lourenco, Diana; Gomez, Christina L. L.; Lee, Chrono K. K.; Hester, Maureen M. M.; Mou, Zhongming; Ostroff, Gary R. R.; Specht, Charles A. A.; Levitz, Stuart M. M.
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Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-09-28
err8
errOAAI
errHester, Maureen M.; Oliveira, Lorena V. N.; Wang, Ruiying; Mou, Zhongming; Lourenco, Diana; Ostroff, Gary R.; Specht, Charles A.; Levitz, Stuart M.
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errSave
Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles
errMBIO
IF4.7
err2022-02-22
err19
errOAAI
errSpecht, Charles A.; Homan, E. Jane; Lee, Chrono K.; Mou, Zhongming; Gomez, Christina L.; Hester, Maureen M.; Abraham, Ambily; Rus, Florentina; Ostroff, Gary R.; Levitz, Stuart M.
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errSave
Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production
errPLOS PATHOGENS
IF4.9
err2021-08-31
err13
errOAAI
errYadav, Bhawna; Specht, Charles A.; Lee, Chrono K.; Pokrovskii, Maria; Huh, Jun R.; Littman, Dan R.; Levitz, Stuart M.
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errSave
Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity
errPLOS PATHOGENS
IF4.9
err2021-03-18
err7
errOAAI
errdos Santos Dias, Lucas; Dobson, Hannah E.; Bakke, Brock Kingstad; Kujoth, Gregory C.; Huang, Junfeng; Kohn, Elaine M.; Taira, Cleison Ledesma; Wang, Huafeng; Supekar, Nitin T.; Fites, J. Scott; Gates, Daisy; Gomez, Christina L.; Specht, Charles A.; Levitz, Stuart M.; Azadi, Parastoo; Li, Lingjun; Suresh, Marulasiddappa; Klein, Bruce S.; Wuthrich, Marcel
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errSave
Vaccines for human fungal diseases: close but still a long way to go
errNPJ VACCINES
IF6.5
err2021-03-03
err87
errOAAI
errOliveira, Lorena V. N.; Wang, Ruiying; Specht, Charles A.; Levitz, Stuart M.
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errSave
The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans
errMBIO
IF4.7
err2019-12-24
err3
errOAAI
errMaybruck, Brian T.; Lam, Woei C.; Specht, Charles A.; Ilagan, Ma. Xenia G.; Donlin, Maureen J.; Lodge, Jennifer K.
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errSave
Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii
errMSPHERE
IF3.1
err2019-10-30
err21
errOAAI
errLam, Woei C.; Upadhya, Rajendra; Specht, Charles A.; Ragsdale, Abigail E.; Hole, Camaron R.; Levitz, Stuart M.; Lodge, Jennifer K.
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errSave
Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis
errMBIO
IF4.7
err2018-12-21
err59
errOAAI
errUpadhya, Rajendra; Baker, Lorina G.; Lam, Woei C.; Specht, Charles A.; Donlin, Maureen J.; Lodge, Jennifer K.
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errSave
Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species
errMBIO
IF4.7
err2017-12-29
err76
errOAAI
errSpecht, Charles A.; Lee, Chrono K.; Huang, Haibin; Hester, Maureen M.; Liu, Jianhua; Luckie, Bridget A.; Santana, Melanie A. Torres; Mirza, Zeynep; Khoshkenar, Payam; Abraham, Ambily; Shen, Zu T.; Lodge, Jennifer K.; Akalin, Ali; Homan, Jane; Ostroff, Gary R.; Levitz, Stuart M.
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errSave
Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma
errPLOS PATHOGENS
IF4.9
err2017-01-17
err79
errOAAI
errGuerra, Evelyn Santos; Lee, Chrono K.; Specht, Charles A.; Yadav, Bhawna; Huang, Haibin; Akalin, Ali; Huh, Jun R.; Mueller, Christian; Levitz, Stuart M.
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errSave
Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat -Killed, Chitosan-Deficient Strain of Cryptococcus neoformans
errMBIO
IF4.7
err2016-07-06
err90
errOAAI
errUpadhya, Rajendra; Lam, Woei C.; Maybruck, Brian; Specht, Charles A.; Levitz, Stuart M.; Lodge, Jennifer K.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Dan R. Littman
H-index: 169 · Papers: 501
A
Arturo Casadevall
H-index: 144 · Papers: 1.5K
L
L. Aravind
H-index: 140 · Papers: 499
J
John R. Perfect
H-index: 121 · Papers: 605
J
José M. C. Ribeiro
H-index: 102 · Papers: 569
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