Not logged in Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism Liley, James; Newnham, Michael; Bleda, Marta; Bunclark, Katherine; Auger, William; Barbera, Joan Albert; Bogaard, Harm; Delcroix, Marion; Fernandes, Timothy M.; Howard, Luke; Jenkins, David; Lang, Irene; Mayer, Eckhard; Rhodes, Chris; Simpson, Michael; Southgate, Laura; Trembath, Richard; Wharton, John; Wilkins, Martin R.; Graf, Stefan; Morrell, Nicholas; Zaba, Joanna Pepke; Toshner, Mark Share Save
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport Liu, Bin; Azfar, Mujahid; Legchenko, Ekaterina; West, James A.; Martin, Shaun; Van den Haute, Chris; Baekelandt, Veerle; Wharton, John; Howard, Luke; Wilkins, Martin R.; Vangheluwe, Peter; Morrell, Nicholas W.; Upton, Paul D. Share Save
Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension Ulrich, Anna; Wu, Yukyee; Draisma, Harmen; Wharton, John; Swietlik, Emilia M.; Cebola, Ines; Vasilaki, Eleni; Balkhiyarova, Zhanna; Jarvelin, Marjo-Riitta; Auvinen, Juha; Herzig, Karl-Heinz; Coghlan, J. Gerry; Lordan, James; Church, Colin; Howard, Luke S.; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen J.; Kiely, David G.; Condliffe, Robin; Lawrie, Allan; Graf, Stefan; Morrell, Nicholas W.; Wilkins, Martin R.; Prokopenko, Inga; Rhodes, Christopher J. Share Save
Restoration of Foxp31 Regulatory T Cells by HDAC-Dependent Epigenetic Modulation Plays a Pivotal Role in Resolving Pulmonary Arterial Hypertension Pathology Chen, Chien-Nien; Hajji, Nabil; Yeh, Fu-Chiang; Rahman, Sunniyat; Ali, Souad; Wharton, John; Baxan, Nicoleta; Zhao, Lin; Xie, Chong-Yang; Chen, Yi-Guan; Frid, Maria G.; Chelladurai, Prakash; Pullamsetti, Soni Savai; Stenmark, Kurt R.; Wilkins, Martin R.; Zhao, Lan Share Save
First Genotype-Phenotype Study in TBX4 Syndrome Gain-of-Function Mutations Causative for Lung Disease Prapa, Matina; Lago-Docampo, Mauro; Swietlik, Emilia M.; Montani, David; Eyries, Melanie; Humbert, Marc; Welch, Carrie L.; Chung, Wendy K.; Berger, Rolf M. F.; Bogaard, Harm Jan; Danhaive, Olivier; Escribano-Subias, Pilar; Gall, Henning; Girerd, Barbara; Hernandez-Gonzalez, Ignacio; Holden, Simon; Hunt, David; Jansen, Samara M. A.; Kerstjens-Frederikse, Wilhelmina; Kiely, David G.; Lapunzina, Pablo; McDermott, John; Moledina, Shahin; Pepke-Zaba, Joanna; Polwarth, Gary J.; Schotte, Gwen; Tenorio-Castano, Jair; Thompson, A. A. Roger; Wharton, John; Wort, Stephen J.; Megy, Karyn; Mapeta, Rutendo; Treacy, Carmen M.; Martin, Jennifer M.; Li, Wei; Swift, Andrew J.; Upton, Paul D.; Morrell, Nicholas W.; Graf, Stefan; Valverde, Diana Share Save
Correlation between right ventricular dysfunction and plasma protein profile in pulmonary hypertension Constantine, A.; Rhodes, C. J.; Ricci, P.; Li, W.; Price, L. C.; Mccabe, C.; Wharton, J.; Wilkins, M. R.; Howard, L. S.; Dimopoulos, K.; Wort, S. J. Share Save
Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood Kariotis, Sokratis; Jammeh, Emmanuel; Swietlik, Emilia M.; Pickworth, Josephine A.; Rhodes, Christopher J.; Otero, Pablo; Wharton, John; Iremonger, James; Dunning, Mark J.; Pandya, Divya; Mascarenhas, Thomas S.; Errington, Niamh; Thompson, A. A. Roger; Romanoski, Casey E.; Rischard, Franz; Garcia, Joe G. N.; Yuan, Jason X. -J.; An, Tae-Hwi Schwantes; Desai, Ankit A.; Coghlan, Gerry; Lordan, Jim; Corris, Paul A.; Howard, Luke S.; Condliffe, Robin; Kiely, David G.; Church, Colin; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen; Graf, Stefan; Morrell, Nicholas W.; Wilkins, Martin R.; Lawrie, Allan; Wang, Dennis Share Save
An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis Ainscough, Alexander J.; Smith, Timothy J.; Haensel, Maike; Rhodes, Christopher J.; Fellows, Adam; Whitwell, Harry J.; Vasilaki, Eleni; Gray, Kelly; Freeman, Adrian; Howard, Luke S.; Wharton, John; Dunmore, Benjamin; Upton, Paul D.; Wilkins, Martin R.; Edel, Joshua B.; Wojciak-Stothard, Beata Share Save
Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension Harbaum, Lars; Rhodes, Christopher J.; Wharton, John; Lawrie, Allan; Karnes, Jason H.; Desai, Ankit A.; Nichols, William C.; Humbert, Marc; Montani, David; Girerd, Barbara; Sitbon, Olivier; Boehm, Mario; Novoyatleva, Tatyana; Schermuly, Ralph T.; Ghofrani, H. Ardeschir; Toshner, Mark; Kiely, David G.; Howard, Luke S.; Swietlik, Emilia M.; Graf, Stefan; Pietzner, Maik; Morrell, Nicholas W.; Wilkins, Martin R. Share Save
Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension Rhodes, Christopher J.; Wharton, John; Swietlik, Emilia M.; Harbaum, Lars; Girerd, Barbara; Coghlan, J. Gerry; Lordan, James; Church, Colin; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen J.; Kiely, David G.; Condliffe, Robin; Lawrie, Allan; Graf, Stefan; Montani, David; Boucly, Athenais; Sitbon, Olivier; Humbert, Marc; Howard, Luke S.; Morrell, Nicholas W.; Wilkins, Martin R. Share Save
Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2 (vol 4, 1002, 2021) Novoyatleva, Tatyana; Rai, Nabham; Kojonazarov, Baktybek; Veeroju, Swathi; Ben-Batalla, Isabel; Caruso, Paola; Shihan, Mazen; Presser, Nadine; Gotz, Elsa; Lepper, Carina; Herpel, Sebastian; Manaud, Gregoire; Perros, Frederic; Gall, Henning; Ghofrani, Hossein Ardeschir; Weissmann, Norbert; Grimminger, Friedrich; Wharton, John; Wilkins, Martin; Upton, Paul D.; Loges, Sonja; Morrell, Nicholas W.; Seeger, Werner; Schermuly, Ralph T. Share Save
Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood Kariotis, Sokratis; Jammeh, Emmanuel; Swietlik, Emilia M.; Pickworth, Josephine A.; Rhodes, Christopher J.; Otero, Pablo; Wharton, John; Iremonger, James; Dunning, Mark J.; Pandya, Divya; Mascarenhas, Thomas S.; Errington, Niamh; Thompson, A. A. Roger; Romanoski, Casey E.; Rischard, Franz; Garcia, Joe G. N.; Yuan, Jason X. -J.; An, Tae-Hwi Schwantes; Desai, Ankit A.; Coghlan, Gerry; Lordan, Jim; Corris, Paul A.; Howard, Luke S.; Condliffe, Robin; Kiely, David G.; Church, Colin; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen; Graf, Stefan; Morrell, Nicholas W.; Wilkins, Martin R.; Lawrie, Allan; Wang, Dennis; Bleda, Marta; Bleda, Marta; Hadinnapola, Charaka; Haimel, Matthias; Auckland, Kate; Tilly, Tobias; Martin, Jennifer M.; Yates, Katherine; Treacy, Carmen M.; Day, Margaret; Greenhalgh, Alan; Shipley, Debbie; Peacock, Andrew J.; Irvine, Val; Kennedy, Fiona; Moledina, Shahin; MacDonald, Lynsay; Tamvaki, Eleni; Barnes, Anabelle; Cookson, Victoria; Chentouf, Latifa; Ali, Souad; Othman, Shokri; Ranganathan, Lavanya; Gibbs, J. Simon R.; DaCosta, Rosa; Pinguel, Joy; Dormand, Natalie; Parker, Alice; Stokes, Della; Ghedia, Dipa; Tan, Yvonne; Ngcozana, Tanaka; Wanjiku, Ivy; Polwarth, Gary; Mackenzie Ross, Rob V.; Suntharalingam, Jay; Grover, Mark; Kirby, Ali; Grove, Ali; White, Katie; Seatter, Annette; Creaser-Myers, Amanda; Walker, Sara; Roney, Stephen; Elliot, Charles A.; Charalampopoulos, Athanasios; Sabroe, Ian; Hameed, Abdul; Armstrong, Iain; Hamilton, Neil; Rothman, Alex M. K.; Swift, Andrew J.; Wild, James M.; Soubrier, Florent; Eyries, Melanie; Humbert, Marc; Montani, David; Girerd, Barbara; Scelsi, Laura; Ghio, Stefano; Gall, Henning; Ghofrani, Ardi; Bogaard, Harm J.; Noordegraaf, Anton Vonk; Houweling, Arjan C.; Veld, Anna Huis in't; Schotte, Gwen Share Save
Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2 Novoyatleva, Tatyana; Rai, Nabham; Kojonazarov, Baktybek; Veeroju, Swathi; Ben-Batalla, Isabel; Caruso, Paola; Shihan, Mazen; Presser, Nadine; Goetz, Elsa; Lepper, Carina; Herpel, Sebastian; Manaud, Gregoire; Perros, Frederic; Gall, Henning; Ghofrani, Hossein Ardeschir; Weissmann, Norbert; Grimminger, Friedrich; Wharton, John; Wilkins, Martin; Upton, Paul D.; Loges, Sonja; Morrell, Nicholas W.; Seeger, Werner; Schermuly, Ralph T. Share Save
A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach Errington, Niamh; Iremonger, James; Pickworth, Josephine A.; Kariotis, Sokratis; Rhodes, Christopher J.; Rothman, Alexander Mk; Condliffe, Robin; Elliot, Charles A.; Kiely, David G.; Howard, Luke S.; Wharton, John; Thompson, A. A. Roger; Morrell, Nicholas W.; Wilkins, Martin R.; Wang, Dennis; Lawrie, Allan Share Save
Supplementation with Iron in Pulmonary Arterial Hypertension Two Randomized Crossover Trials Howard, Luke S. G. E.; He, Jianguo; Watson, Geoffrey M. J.; Huang, Li; Wharton, John; Luo, Qin; Kiely, David G.; Condliffe, Robin; Pepke-Zaba, Joanna; Morrell, Nicholas W.; Sheares, Karen K.; Ulrich, Anna; Quan, Ruilin; Zhao, Zhihui; Jing, Xiaoli; An, Chenhong; Liu, Zhihong; Xiong, Changming; Robbins, Peter A.; Dawes, Timothy; de Marvao, Antonio; Rhodes, Christopher J.; Richter, Manuel J.; Gall, Henning; Ghofrani, Hossein A.; Zhao, Lan; Huson, Les; Wilkins, Martin R. Share Save
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Bayesian Inference Associates Rare KDR Variants With Specific Phenotypes in Pulmonary Arterial Hypertension Swietlik, Emilia M.; Greene, Daniel; Zhu, Na; Megy, Karyn; Cogliano, Marcella; Rajaram, Smitha; Pandya, Divya; Tilly, Tobias; Lutz, Katie A.; Welch, Carrie C. L.; Pauciulo, Michael W.; Southgate, Laura; Martin, Jennifer M.; Treacy, Carmen M.; Penkett, Christopher J.; Stephens, Jonathan C.; Bogaard, Harm J.; Church, Colin; Coghlan, Gerry; Coleman, Anna W.; Condliffe, Robin; Eichstaedt, Christina A.; Eyries, Melanie; Gall, Henning; Ghio, Stefano; Girerd, Barbara; Grunig, Ekkehard; Holden, Simon; Howard, Luke; Humbert, Marc; Kiely, David G.; Kovacs, Gabor; Lordan, Jim; Machado, Rajiv D.; Ross, Robert V. Mackenzie; McCabe, Colm; Moledina, Shahin; Montani, David; Olschewski, Horst; Pepke-Zaba, Joanna; Price, Laura; Rhodes, Christopher J.; Seeger, Werner; Soubrier, Florent; Suntharalingam, Jay; Toshner, Mark R.; Noordegraaf, Anton Vonk; Wharton, John; Wild, James M.; Wort, Stephen John; Lawrie, Allan; Wilkins, Martin R.; Trembath, Richard C.; Shen, Yufeng; Chung, Wendy K.; Swift, Andrew J.; Nichols, William C.; Morrell, Nicholas W.; Graf, Stefan Share Save
Multi-omic profiling in pulmonary arterial hypertension Otero-Nunez, Pablo; Rhodes, Christopher; Wharton, John; Swietlik, Emilia; Kariotis, Sokratis; Harbaum, Lars; Dunning, Mark; Elinoff, Jason; Errington, Niamh; Thomson, Roger; Iremonger, James; Coghlan, Gerry; Corris, Paul; Howard, Luke; Kiely, David; Church, Colin; Pepke-Zaba, Joanna; Toshner, Mark; Wort, Stephen; Desai, Ankit; Humbert, Marc; Nichols, William; Southgate, Laura; Tregouet, David-Alexandre; Trembath, Richard; Prokopenko, Inga; Graf, Stefan; Morrell, Nicholas; Wang, Dennis; Lawrie, Allan; Wilkins, Martin Share Save
Plasma metabolomics in chronic thromboembolic pulmonary hypertension Swietlik, Emilia; Ghataorhe, Pavandeep; Zalewska, Kasia; Wharton, John; Howard, Luke S.; Taboada, Dolores; Cannon, John E.; Morrell, Nicholas W.; Wilkins, Martin R.; Toshner, Mark R.; Pepke-Zaba, Joanna; Rhodes, Christopher J. Share Save
Plasma metabolomics exhibit response to therapy in chronic thromboembolic pulmonary hypertension Swietlik, Emilia M.; Ghataorhe, Pavandeep; Zalewska, Kasia, I; Wharton, John; Howard, Luke S.; Taboada, Dolores; Cannon, John E.; Morrell, Nicholas W.; Wilkins, Martin R.; Toshner, Mark; Pepke-Zaba, Joanna; Rhodes, Christopher J. Share Save
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