Not logged in SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF- driven age- dependent severe disease with human correlates Bader, Stefanie M.; Cooney, James P.; Sheerin, Dylan; Taiaroa, George; Harty, Leigh; Davidson, Kathryn C.; Mackiewicz, Liana; Dayton, Merle; Wilcox, Stephen; Whitehead, Lachlan; Rogers, Kelly L.; Georgy, Smitha Rose; Coussens, Anna K.; Grimley, Samantha L.; Corbin, Vincent; Pitt, Miranda; Coin, Lachlan; Pickering, Raelene; Thomas, Merlin; Allison, Cody C.; McAuley, Julie; Purcell, Damian F. J.; Doerflinger, Marcel; Pellegrini, Marc Share Save
Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice Hanssen, Nordin M. J.; Tikellis, Chris; Pickering, Raelene J.; Dragoljevic, Dragana; Lee, Man Kit Sam; Block, Tomasz; Scheijen, Jean L. J. M.; Wouters, Kristiaan; Miyata, Toshio; Cooper, Mark E.; Murphy, Andrew J.; Thomas, Merlin C.; Schalkwijk, Casper G. Share Save
Share Save
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice Pymm, Phillip; Adair, Amy; Chan, Li-Jin; Cooney, James P.; Mordant, Francesca L.; Allison, Cody C.; Lopez, Ester; Haycroft, Ebene R.; O'Neill, Matthew T.; Tan, Li Lynn; Dietrich, Melanie H.; Drew, Damien; Doerflinger, Marcel; Dengler, Michael A.; Scott, Nichollas E.; Wheatley, Adam K.; Gherardin, Nicholas A.; Venugopal, Hariprasad; Cromer, Deborah; Davenport, Miles P.; Pickering, Raelene; Godfrey, Dale, I; Purcell, Damian F. J.; Kent, Stephen J.; Chung, Amy W.; Subbarao, Kanta; Pellegrini, Marc; Glukhova, Alisa; Tham, Wai-Hong Share Save
Share Save
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis Flynn, Michelle C.; Kraakman, Michael J.; Tikellis, Christos; Lee, Man K. S.; Hanssen, Nordin M. J.; Kammoun, Helene L.; Pickering, Raelene J.; Dragoljevic, Dragana; Al-Sharea, Annas; Barrett, Tessa J.; Hortle, Fiona; Byrne, Frances L.; Olzomer, Ellen; McCarthy, Domenica A.; Schalkwijk, Casper G.; Forbes, Josephine M.; Hoehn, Kyle; Makowski, Liza; Lancaster, Graeme I.; El-Osta, Assam; Fisher, Edward A.; Goldberg, Ira J.; Cooper, Mark E.; Nagareddy, Prabhakara R.; Thomas, Merlin C.; Murphy, Andrew J. Share Save
Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis Pickering, Raelene J.; Tikellis, Christos; Rosado, Carlos J.; Tsorotes, Despina; Dimitropoulos, Alexandra; Smith, Monique; Huet, Olivier; Seeber, Ruth M.; Abhayawardana, Rekhati; Johnstone, Elizabeth K. M.; Golledge, Jonathan; Wang, Yutang; Jandeleit-Dahm, Karin A.; Cooper, Mark E.; Pfleger, Kevin D. G.; Thomas, Merlin C. Share Save
A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation Mathew, Geetha; Sharma, Arpeeta; Pickering, Raelene J.; Rosado, Carlos J.; Lemarie, Jeremie; Mudgal, Jayesh; Thambi, Magith; Sebastian, Sarine; Jandeleit-Dahm, Karin A.; de Haan, Judy B.; Unnikrishnan, Mazhuvancherry K. Share Save
Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis Brennan, Eoin P.; Mohan, Muthukumar; McClelland, Aaron; de Gaetano, Monica; Tikellis, Christos; Marai, Mariam; Crean, Daniel; Dai, Aozhi; Beuscart, Ophelie; Derouiche, Sinda; Gray, Stephen P.; Pickering, Raelene; Tan, Sih Min; Godson-Treacy, Molly; Sheehan, Stephen; Dowdall, Joseph F.; Barry, Mary; Belton, Orina; Ali-Shah, Syed Tasadaque; Guiry, Patrick J.; Jandeleit-Dahm, Karin; Cooper, Mark E.; Godson, Catherine; Kantharidis, Phillip Share Save
Relationship Between Plasma 8-OH-Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial Thomas, Merlin C.; Woodward, Mark; Li, Qiang; Pickering, Raelene; Tikellis, Christos; Poulter, Neil; Cooper, Mark E.; Marre, Michel; Zoungas, Sophia; Chalmers, John Share Save
Lipoxins Regulate the Early Growth Response-1 Network and Reverse Diabetic Kidney Disease Brennan, Eoin P.; Mohan, Muthukumar; McClelland, Aaron; Tikellis, Christos; Ziemann, Mark; Kaspi, Antony; Gray, Stephen P.; Pickering, Raelene; Tan, Sih Min; Ali-Shah, Syed Tasadaque; Guiry, Patrick J.; El-Osta, Assam; Jandeleit-Dahm, Karin; Cooper, Mark E.; Godson, Catherine; Kantharidis, Phillip Share Save
RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis Hagiwara, Shinji; Sourris, Karly; Ziemann, Mark; Wu Tieqiao; Mohan, Muthukumar; McClelland, Aaron D.; Brennan, Eoin; Forbes, Josephine; Coughlan, Melinda; Harcourt, Brooke; Penfold, Sally; Wang, Bo; Higgins, Gavin; Pickering, Raelene; El-Osta, Assam; Thomas, Merlin C.; Cooper, Mark E.; Kantharidis, Phillip Share Save
Share Save
The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy De Blasio, Miles J.; Ramalingam, Anand; Cao, Anh H.; Prakoso, Darnel; Ye, Ji-Ming; Pickering, Raelene; Watson, Anna M. D.; de Haan, Judy B.; Kaye, David M.; Ritchie, Rebecca H. Share Save
Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis Brennan, Eoin; Wang, Bo; McClelland, Aaron; Mohan, Muthukumar; Marai, Mariam; Beuscart, Ophelie; Derouiche, Sinda; Gray, Stephen; Pickering, Raelene; Tikellis, Chris; de Gaetano, Monica; Barry, Mary; Belton, Orina; Ali-Shah, Syed Tasadaque; Guiry, Patrick; Jandeleit-Dahm, Karin A. M.; Cooper, Mark E.; Godson, Catherine; Kantharidis, Phillip Share Save
Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock Huet, Olivier; Pickering, Raelene J.; Tikellis, Chris; Latouche, Celine; Long, Fenella; Kingwell, Bronwyn; Dickinson, Bryan; Chang, Chris J.; Masters, Seth; Mackay, Fabienne; Cooper, Mark E.; de Haan, Judy B. Share Save
Share Save
Relationship Between Levels of Advanced Glycation End Products and Their Soluble Receptor and Adverse Outcomes in Adults With Type 2 Diabetes Thomas, Merlin C.; Woodward, Mark; Neal, Bruce; Li, Qiang; Pickering, Raelene; Marre, Michel; Williams, Bryan; Perkovic, Vlado; Cooper, Mark E.; Zoungas, Sophia; Chalmers, John; Hillis, Graham S. Share Save
ACE2 deficiency shifts energy metabolism towards glucose utilization Bernardi, Stella; Tikellis, Christos; Candido, Riccardo; Tsorotes, Despina; Pickering, Raelene J.; Bossi, Fleur; Carretta, Renzo; Fabris, Bruno; Cooper, Mark E.; Thomas, Merlin C. Share Save
Share Save