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S

Stijn De Langhe

mayo clinic

43H-index
90Paper Count
6.2KCitation Count
Published Papers 32
Publication Date
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Epithelial-mesenchymal cell competition coordinates fate transitions across tissue compartments during lung development and fibrosis
errNature Communications
IF15.7
err2025-11-21
err0
errOAAI
errKylie Klinkhammer; Rachel Warren; Joseph Knopp; Toan Nguyen; Stijn P. De Langhe
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errSave
A molecular circuit regulates fate plasticity in emerging and adult AT2 cells
errNature Communications
IF15.7
err2025-10-14
err0
errOAAI
errAmitoj S. Sawhney; Brian J. Deskin; Junming Cai; Daniel Gibbard; Gibran Ali; Annika Utoft; Xianmei Qi; Aaron Olson; Hannah Hausman; Liberty Sabol; Shannon Holmberg; Ria Shah; Rachel Warren; Stijn De Langhe; Zintis Inde; Kristopher A. Sarosiek; Evan Lemire; Adam Haber; Liu Wang; Zong Wei; Rui Benedito; Douglas G. Brownfield
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errSave
Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models
errNature Communications
IF15.7
err2025-08-02
err0
errOAAI
errDarcy Elizabeth Wagner; Hani N. Alsafadi; Nilay Mitash; Aurelien Justet; Qianjiang Hu; Ricardo Pineda; Claudia Staab-Weijnitz; Martina Korfei; Nika Gvazava; Kristin Wannemo; Ugochi Onwuka; Molly Mozurak; Adriana Estrada-Bernal; Juan Cala-Garcia; Katrin Mutze; Rita Costa; Deniz Bölükbas; John Stegmayr; Wioletta Skronska-Wasek; Stephan Klee; Chiharu Ota; Hoeke A. Baarsma; Jingtao Wang; John Sembrat; Anne Hilgendorff; Jun Ding; Andreas Günther; Rachel Chambers; Ivan Rosas; Stijn de Langhe; Naftali Kaminski; Mareike Lehmann; Oliver Eickelberg; Melanie Königshoff
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errSave
Renal Neoplasia in Birt-Hogg-Dubé Syndrome: Integrated Histopathologic, Bulk, and Single-cell Transcriptomic Analysis
errEuropean Urology
IF25.2
err2025-04-18
err0
PREAI
errSounak Gupta; Surendra Dasari; Rachel R. Warren; Wei Shen; Rhianna M. Urban; Melissa L. Stanton; Christine M. Lohse; Megan A. Holdren; Megan F. Hoenig; Beth A. Pitel; Stephanie A. Smoley; Stefan W. Nelson; Nate R. Torell; Autumn C. Moon; Leah M. Nelson; Joaquin J. Garcia; Peter C. Lucas; Kevin C. Halling; Benjamin R. Kipp; Stephen A. Boorjian; Stijn P. De Langhe; Lori A. Erickson; Vidit Sharma; John C. Cheville; Bradley C. Leibovich
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errSave
Cell competition drives bronchiolization and pulmonary fibrosis
errNATURE COMMUNICATIONS
IF15.7
err2024-12-05
err0
errOAAI
errWarren, Rachel; Klinkhammer, Kylie; Lyu, Handeng; Knopp, Joseph; Yuan, Tingting; Yao, Changfu; Stripp, Barry; De Langhe, Stijn P.
errShare
errSave
Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis
errELIFE
IF0
err2023-05-11
err17
errOAAI
errWarren, Rachel; Lyu, Handeng; Klinkhammer, Kylie; De Langhe, Stijn P.
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errSave
Niche-mediated repair of airways is directed in an occupant-dependent manner
errCELL REPORTS
IF6.9
err2022-12-01
err3
errOAAI
errLyu, Handeng; Warren, Rachel; Gao, Shan; Klinkhammer, Kylie; Yuan, Tingting; Zhang, Jin-San; Brownfield, Douglas; Li, Xiaokun; Langhe, Stijn P. De
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errSave
Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration
errCELL REPORTS
IF6.9
err2020-12-01
err27
errOAAI
errMoiseenko, Alena; Vazquez-Armendariz, Ana Ivonne; Kheirollahi, Vahid; Chu, Xuran; Tata, Aleksandra; Rivetti, Stefano; Guenther, Stefan; Lebrigand, Kevin; Herold, Susanne; Braun, Thomas; Mari, Bernard; De Langhe, Stijn; Kwapiszewska, Grazyna; Guenther, Andreas; Chen, Chengshui; Seeger, Werner; Tata, Purushothama Rao; Zhang, Jin-San; Bellusci, Saverio; El Agha, Elie
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errSave
The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy
errTHERANOSTICS
IF13.3
err2020-01-01
err15
errOAAI
errGuo, Qiang; Quan, Meiyu; Dong, Jinglai; Bai, Jing; Wang, Jie; Han, Rui; Wang, Wei; Cai, Yaxin; Lv, Yuqing; Chen, Qianjie; Xu, Huijing; Lyu, Handen; Deng, Liancheng; Zhou, Depu; Xiao, Xueyuan; De langhe, Stijn; Billadeau, Daniel D.; Lou, Zhenkun; Zhang, Jin-San
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errSave
The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy (vol 10, pg 4422, 2020)
errTHERANOSTICS
IF13.3
err2020-01-01
err0
errOAAI
errGuo, Qiang; Quan, Meiyu; Dong, Jinglai; Bai, Jing; Wang, Jie; Han, Rui; Wang, Wei; Cai, Yaxin; Lv, Yu-Qing; Chen, Qianjie; Xu, Huijing; Lyu, Han-Deng; Deng, Liancheng; Zhou, Depu; Xiao, Xueyuan; De Langhe, Stijn; Billadeau, Daniel D.; Lou, Zhenkun; Zhang, Jin-San
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errSave
FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury
errSTEM CELL REPORTS
IF5.1
err2019-05-01
err91
errOAAI
errYuan, Tingting; Volckaert, Thomas; Redente, Elizabeth F.; Hopkins, Seantel; Klinkhammer, Kylie; Wasnick, Roxana; Chao, Cho-Ming; Yuan, Jie; Zhang, Jin-San; Yao, Changfu; Majka, Susan; Stripp, Barry R.; Gunther, Andreas; Riches, David W. H.; Bellusci, Saverio; Thannickal, Victor J.; De Langhe, Stijn P.
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errSave
Developmental pathways in the pathogenesis of lung fibrosis
errMOLECULAR ASPECTS OF MEDICINE
IF10.3
err2019-02-01
err338
errOAAI
errChanda, Diptiman; Otoupalova, Eva; Smith, Samuel R.; Volckaert, Thomas; De Langhe, Stijn P.; Thannickal, Victor J.
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errSave
Protein Tyrosine Phosphatase-N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2018-10-01
err23
errOAAI
errBamberg, Alison; Redente, Elizabeth F.; Groshong, Steve D.; Tuder, Rubin M.; Cool, Carlyne D.; Keith, Rebecca C.; Edelman, Benjamin L.; Black, Bart P.; Cosgrove, Gregory P.; Wynes, Murry W.; Curran-Everett, Douglas; De langhe, Stijn; Ortiz, Luis A.; Thorburn, Andrew; Riches, David W. H.
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errSave
Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells
errDEVELOPMENTAL CELL
IF8.7
err2017-10-01
err98
errOAAI
errVolckaert, Thomas; Yuan, Tingting; Chao, Cho-Ming; Bell, Harold; Sitaula, Alina; Szimmtenings, Luisa; El Agha, Elie; Chanda, Diptiman; Majka, Susan; Bellusci, Saverio; Thannickal, Victor J.; Faessler, Reinhard; De langhe, Stijn P.
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errSave
Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2017-05-02
err37
errOAAI
errGaskill, Christa F.; Carrier, Erica J.; Kropski, Jonathan A.; Bloodworth, Nathaniel C.; Menon, Swapna; Foronjy, Robert F.; Taketo, M. Mark; Hong, Charles C.; Austin, Eric D.; West, James D.; Means, Anna L.; Loyd, James E.; Merryman, W. David; Hemnes, Anna R.; De Langhe, Stijn; Blackwell, Timothy S.; Klemm, Dwight J.; Majka, Susan M.
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errSave
Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis (vol 20, pg 261, 2017)
errCELL STEM CELL
IF20.4
err2017-04-01
err53
errOAAI
errEl Agha, Elie; Moiseenko, Alena; Kheirollahi, Vahid; De langhe, Stijn; Crnkovic, Slaven; Kwapiszewska, Grazyna; Szibor, Marten; Kosanovic, Djuro; Schwind, Felix; Schermuly, Ralph T.; Henneke, Ingrid; MacKenzie, BreAnne; Quantius, Jennifer; Herold, Susanne; Ntokou, Aglaia; Ahlbrecht, Katrin; Braun, Thomas; Morty, Rory E.; Guenther, Andreas; Seeger, Werner; Bellusci, Saverio
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errSave
Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis
errCELL STEM CELL
IF20.4
err2017-02-01
err196
errOAAI
errEl Agha, Elie; Moiseenko, Alena; Kheirollahi, Vahid; De langhe, Stijn; Crnkovic, Slaven; Kwapiszewska, Grazyna; Kosanovic, Djuro; Schwind, Felix; Schermuly, Ralph T.; Henneke, Ingrid; MacKenzie, BreAnne; Quantius, Jennifer; Herold, Susanne; Ntokou, Aglaia; Ahlbrecht, Katrin; Morty, Rory E.; Guenther, Andreas; Seeger, Werner; Bellusci, Saverio
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errSave
Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis
errSCIENTIFIC REPORTS
IF3.9
err2016-11-21
err42
errOAAI
errChanda, Diptiman; Kurundkar, Ashish; Rangarajan, Sunad; Locy, Morgan; Bernard, Karen; Sharma, Nirmal S.; Logsdon, Naomi J.; Liu, Hui; Crossman, David K.; Horowitz, Jeffrey C.; De Langhe, Stijn; Thannickal, Victor J.
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errSave
Progenitors of Secondary Crest Myofibroblasts Are Developmentally Committed in Early Lung Mesoderm
errStem Cells
IF3.6
err2015-02-17
err84
errOAAI
errLi, Changgong; Li, Min; Li, Sha; Xing, Yiming; Yang, Chang-Yo; Li, Aimin; Borok, Zea; De langhe, Stijn; Minoo, Parviz
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errSave
Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development
errDEVELOPMENT
IF3.6
err2015-01-01
err81
errOAAI
errAl Alam, Denise; El Agha, Elie; Sakurai, Reiko; Kheirollahi, Vahid; Moiseenko, Alena; Danopoulos, Soula; Shrestha, Amit; Schmoldt, Carole; Quantius, Jennifer; Herold, Susanne; Chao, Cho-Ming; Tiozzo, Caterina; De Langhe, Stijn; Plikus, Maksim V.; Thornton, Matthew; Grubbs, Brendan; Minoo, Parviz; Rehan, Virender K.; Bellusci, Saverio
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Research Directions

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Co-authors
Cooperation Journals
A
Anthony Atala
H-index: 142 · Papers: 2.0K
W
Werner Seeger
H-index: 130 · Papers: 2.4K
M
Makoto M. Taketo
H-index: 128 · Papers: 688
P
Peter M. Henson
H-index: 128 · Papers: 472
R
Reinhard Fässler
H-index: 121 · Papers: 688
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