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Adriana Heguy

NYU Grossman School of Medicine

84H-index
560Paper Count
3.3WCitation Count
Published Papers 143
Publication Date
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Motif grammar and transcriptional programs decouple CTCF binding from nucleosome phasing to control cell-type-specific chromatin insulation
errCell Reports
IF6.9
err2026-04-29
err0
errOAAI
errCatherine Do; Guimei Jiang; Paul Zappile; Adriana Heguy; Jane A. Skok
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Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer’s Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations
errthe faseb journal
IF0
err2026-04-03
err0
errOAAI
errMelissa J. Alldred; Kyrillos W. Ibrahim; Harshitha Pidikiti; Sang Han Lee; Adriana Heguy; Gabriela Chiosis; Elliott J. Mufson; Grace E. Stutzmann; Stephen D. Ginsberg
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errSave
Multi-omics analysis of a pig-to-human decedent kidney xenotransplant
errNature
IF48.5
err2025-11-13
err0
PREAI
errEloi Schmauch; Brian D. Piening; Alexa K. Dowdell; Maedeh Mohebnasab; Simon H. Williams; Alexey Stukalov; Fred L. Robinson; Robin Bombardi; Ian Jaffe; Karen Khalil; Jacqueline Kim; Imad Aljabban; Tal Eitan; Darragh P. O’Brien; Mercy Rophina; Chan Wang; Alexandra Q. Bartlett; Francesca Zanoni; Jon Albay; David Andrijevic; Berk Maden; Vincent Mauduit; Susanna Vikman; Diana Argibay; Zasha Zayas; Leah Wu; Kiana Moi; Billy Lau; Weimin Zhang; Loren Gragert; Elaina Weldon; Hui Gao; Lauren Hamilton; Larisa Kagermazova; Brendan R. Camellato; Divya Gandla; Riyana Bhatt; Sarah Gao; Rudaynah A. Al-Ali; Alawi H. Habara; Andrew Chang; Shadi Ferdosi; Han M. Chen; Jennifer D. Motter; Fiorella A. Chacon; Scott C. Thomas; Deepak Saxena; Robert L. Fairchild; Alexandre Loupy; Adriana Heguy; Ali Crawford; Serafim Batzoglou; Michael P. Snyder; Asim Siddiqui; Michael V. Holmes; Anita S. Chong; Minna U. Kaikkonen; Suvi Linna-Kuosmanen; David Ayares; Marc Lorber; Anoma Nellore; Edward Y. Skolnik; Aprajita Mattoo; Vasishta S. Tatapudi; Ryan Taft; Massimo Mangiola; Qian Guo; Ramin S. Herati; Jeffrey Stern; Adam Griesemer; Manolis Kellis; Jef D. Boeke; Robert A. Montgomery; Brendan J. Keating
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errSave
Aging, Rather than Genotype, Is the Principal Contributor to Differential Gene Expression Within Targeted Replacement APOE2, APOE3, and APOE4 Mouse Brain
errBrain Sciences 2025, Vol. 15, Page 1117
IF0
err2025-10-17
err0
errOAAI
errAmanda Labuza; Harshitha Pidikiti; Melissa J. Alldred; Kyrillos W. Ibrahim; Katherine Y. Peng; Jonathan Pasato; Adriana Heguy; Paul M. Mathews; Stephen D. Ginsberg
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errSave
Evaluation of the gut microbiome and sex hormones in postmenopausal women with newly diagnosed hormone receptor-positive breast cancer versus healthy women: a prospective case-control study
errJournal of Cancer Research and Clinical Oncology
IF2.8
err2025-10-04
err0
errOAAI
errMaryann Kwa; Grant Hussey; Yelena Novik; Adrian A. Franke; Angelina Volkova; Karina Flores; Martin J. Blaser; James Speyer; Ruth Oratz; Marleen Meyers; Komal Jhaveri; Ezeddin Fadel; Adriana Heguy; Jonas Schluter; Kelly V. Ruggles; Sylvia Adams
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errSave
Frontal cortex pyramidal neuron expression profiles differentiate the prodromal stage from progressive degeneration across the Alzheimer's disease spectrum
errAlzheimer's & Dementia
IF11.1
err2025-07-25
err0
errOAAI
errAmanda Labuza; Melissa J. Alldred; Harshitha Pidikiti; Michael H. Malek-Ahmadi; Sang Han Lee; Adriana Heguy; Paul D. Coleman; Souparna Chakrabarty
errShare
errSave
Profiling lamina specific pyramidal neurons using postmortem human formalin fixed paraffin embedded frontal cortex tissue in combination with digital spatial profiling
errJournal of Neuroscience Methods
IF2.3
err2025-06-03
err0
errOAAI
errAleksandra Stanisavljevic; Kyrillos W. Ibrahim; Philip H. Stavrides; Christopher Bare; Melissa J. Alldred; Adriana Heguy; Ralph A. Nixon; Stephen D. Ginsberg
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errSave
Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease
errFRONTIERS IN MOLECULAR NEUROSCIENCE
IF3.8
err2025-02-26
err0
errOAAI
errAlldred, Melissa J.; Ibrahim, Kyrillos W.; Pidikiti, Harshitha; Lee, Sang Han; Heguy, Adriana; Chiosis, Gabriela; Mufson, Elliott J.; Stutzmann, Grace E.; Ginsberg, Stephen D.
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errSave
Hippocampal CA1 Pyramidal NeuronsDisplay Sublayer and Circuitry Dependent Degenerative Expression Profiles in Aged Female Down Syndrome Mice
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2024-08-20
err3
PREAI
errAlldred, Melissa J.; Pidikiti, Harshitha; Ibrahim, Kryillos W.; Lee, Sang Han; Heguy, Adriana; Hoffman, Gabriel E.; Mufson, Elliott J.; Stutzmann, Grace E.; Ginsberg, Stephen D.
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errSave
Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome
errACTA NEUROPATHOLOGICA
IF9.3
err2024-08-06
err2
PREAI
errAlldred, Melissa J.; Pidikiti, Harshitha; Ibrahim, Kyrillos W.; Lee, Sang Han; Heguy, Adriana; Hoffman, Gabriel E.; Roussos, Panos; Wisniewski, Thomas; Wegiel, Jerzy; Stutzmann, Grace E.; Mufson, Elliott J.; Ginsberg, Stephen D.
errShare
errSave
Cellular dynamics in pig-to-human kidney xenotransplantation
errMED
IF11.8
err2024-08-01
err4
errOAAI
errPan, Wanqing; Zhang, Weimin; Zheng, Binghan; Camellato, Brendan R.; Stern, Jeffrey; Lin, Ziyan; Khodadadi-Jamayran, Alireza; Kim, Jacqueline; Sommer, Philip; Khalil, Karen; Weldon, Elaina; Bai, Jiangshan; Zhu, Yinan; Meyn, Peter; Heguy, Adriana; Mangiola, Massimo; Griesemer, Adam; Keating, Brendan J.; Montgomery, Robert A.; Xia, Bo; Boeke, Jef D.
errShare
errSave
MethNet: a robust approach to identify regulatory hubs and their distal targets from cancer data
errNATURE COMMUNICATIONS
IF15.7
err2024-07-17
err0
errOAAI
errSakellaropoulos, Theodore; Do, Catherine; Jiang, Guimei; Cova, Giulia; Meyn, Peter; Dimartino, Dacia; Ramaswami, Sitharam; Heguy, Adriana; Tsirigos, Aristotelis; Skok, Jane A.
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errSave
Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging
errTRAFFIC
IF2.5
err2024-05-22
err1
errOAAI
errPeng, Katherine Y.; Liemisa, Braison; Pasato, Jonathan; D'Acunzo, Pasquale; Pawlik, Monika; Heguy, Adriana; Penikalapati, Sai C.; Labuza, Amanda; Pidikiti, Harshitha; Alldred, Melissa J.; Ginsberg, Stephen D.; Levy, Efrat; Mathews, Paul M.
errShare
errSave
Integrative multi-omics profiling in human decedents receiving pig heart xenografts
errNATURE MEDICINE
IF50
err2024-05-17
err9
PREAI
errSchmauch, Eloi; Piening, Brian; Mohebnasab, Maedeh; Xia, Bo; Zhu, Chenchen; Stern, Jeffrey; Zhang, Weimin; Dowdell, Alexa K.; Kim, Jacqueline I.; Andrijevic, David; Khalil, Karen; Jaffe, Ian S.; Loza, Bao-Li; Gragert, Loren; Camellato, Brendan R.; Oliveira, Michelli F.; O'Brien, Darragh P.; Chen, Han M.; Weldon, Elaina; Gao, Hui; Gandla, Divya; Chang, Andrew; Bhatt, Riyana; Gao, Sarah; Lin, Xiangping; Reddy, Kriyana P.; Kagermazova, Larisa; Habara, Alawi H.; Widawsky, Sophie; Liang, Feng-Xia; Sall, Joseph; Loupy, Alexandre; Heguy, Adriana; Taylor, Sarah E. B.; Zhu, Yinan; Michael, Basil; Jiang, Lihua; Jian, Ruiqi; Chong, Anita S.; Fairchild, Robert L.; Linna-Kuosmanen, Suvi; Kaikkonen, Minna U.; Tatapudi, Vasishta; Lorber, Marc; Ayares, David; Mangiola, Massimo; Narula, Navneet; Moazami, Nader; Pass, Harvey; Herati, Ramin S.; Griesemer, Adam; Kellis, Manolis; Snyder, Michael P.; Montgomery, Robert A.; Boeke, Jef D.; Keating, Brendan J.
errShare
errSave
Emergence and dissemination of SARS-CoV-2 XBB.1.5 in New York
errVIRUS EVOLUTION
IF4
err2024-05-07
err1
errOAAI
errGambaro, Fabiana; Duerr, Ralf; Dimartino, Dacia; Marier, Christian; Iturrate, Eduardo; Mulligan, Mark J.; Heguy, Adriana; Dellicour, Simon
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errSave
Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
errNATURE COMMUNICATIONS
IF15.7
err2023-11-08
err4
errOAAI
errDolgalev, Igor; Zhou, Hua; Murrell, Nina; Le, Hortense; Sakellaropoulos, Theodore; Coudray, Nicolas; Zhu, Kelsey; Vasudevaraja, Varshini; Yeaton, Anna; Goparaju, Chandra; Li, Yonghua; Sulaiman, Imran; Tsay, Jun-Chieh J.; Meyn, Peter; Mohamed, Hussein; Sydney, Iris; Shiomi, Tomoe; Ramaswami, Sitharam; Narula, Navneet; Kulicke, Ruth; Davis, Fred P.; Stransky, Nicolas; Smolen, Gromoslaw A.; Cheng, Wei-Yi; Cai, James; Punekar, Salman; Velcheti, Vamsidhar; Sterman, Daniel H.; Poirier, J. T.; Neel, Ben; Wong, Kwok-Kin; Chiriboga, Luis; Heguy, Adriana; Papagiannakopoulos, Thales; Nadorp, Bettina; Snuderl, Matija; Segal, Leopoldo N.; Moreira, Andre L.; Pass, Harvey I.; Tsirigos, Aristotelis
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errSave
Selective adaptation of SARS-CoV-2 Omicron under booster vaccine pressure: a multicentre observational study
errEBIOMEDICINE
IF10.8
err2023-11-01
err7
errOAAI
errDuerr, Ralf; Dimartino, Dacia; Marier, Christian; Zappile, Paul; Wang, Guiqing; Francois, Fritz; Ortigoza, Mila B.; Iturrate, Eduardo; Samanovic, Marie I.; Mulligan, Mark J.; Heguy, Adriana
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errSave
Generation of quality-controled SARS-CoV-2 variant stocks
errNATURE PROTOCOLS
IF16
err2023-10-13
err0
PREAI
errde Vries, Maren; Ciabattoni, Grace O.; Rodriguez-Rodriguez, Bruno A.; Crosse, Keaton M.; Papandrea, Dominick; Samanovic, Marie I.; Dimartino, Dacia; Marier, Christian; Mulligan, Mark J.; Heguy, Adriana; Desvignes, Ludovic; Duerr, Ralf; Dittmann, Meike
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errSave
De novo assembly and annotation of the singing mouse genome
errBMC GENOMICS
IF3.7
err2023-09-26
err0
errOAAI
errSmith, Samantha K.; Frazel, Paul W.; Khodadadi-Jamayran, Alireza; Zappile, Paul; Marier, Christian; Okhovat, Mariam; Brown, Stuart; Long, Michael A.; Heguy, Adriana; Phelps, Steven M.
errShare
errSave
Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment (vol 14, 797, 2023)
errNATURE COMMUNICATIONS
IF15.7
err2023-07-03
err0
errOAAI
errWerba, Gregor; Weissinger, Daniel; Kawaler, Emily A.; Zhao, Ende; Kalfakakou, Despoina; Dhara, Surajit; Wang, Lidong; Lim, Heather B.; Oh, Grace; Jing, Xiaohong; Beri, Nina; Khanna, Lauren; Gonda, Tamas; Oberstein, Paul; Hajdu, Cristina; Loomis, Cynthia; Heguy, Adriana; Sherman, Mara H.; Lund, Amanda W.; Welling, Theodore H.; Dolgalev, Igor; Tsirigos, Aristotelis; Simeone, Diane M.
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errSave

Research Directions

No research directions
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