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ONTARGET: Phase 3 randomized, double-blind, placebo-controlled trial evaluating crofelemer for the prophylaxis of diarrhea in adult patients with solid tumors receiving targeted therapies with or without standard chemotherapy Schwartzberg, Lee; Okhuysen, Pablo; Roeland, Eric; Vidal, Gregory; Harnden, Kathleen; Zuniga, Richard; Bosnjak, Snezana; Daggubati, Sreedevi; Bursac, Daliborka Share Save
A Randomized, Double-Blind, Phase 3 Safety and Efficacy Study of Ridinilazole Versus Vancomycin for Treatment of Clostridioides difficile Infection: Clinical Outcomes With Microbiome and Metabolome Correlates of Response Okhuysen, Pablo C.; Ramesh, Mayur S.; Louie, Thomas; Kiknadze, Nino; Torre-Cisneros, Julian; de Oliveira, Claudia Murta; Van Steenkiste, Christophe; Stychneuskaya, Alena; Garey, Kevin W.; Garcia-Diaz, Julia; Li, Jianling; Duperchy, Esther; Chang, Betty Y.; Sukbuntherng, Juthamas; Montoya, Jose G.; Styles, Lori; Clow, Fong; James, Danelle; Dubberke, Erik R.; Wilcox, Mark Share Save
Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial Zhang, Xiaotao; Irajizad, Ehsan; Hoffman, Kristi L.; Fahrmann, Johannes F.; Li, Fangyu; Seo, Yongwoo David; Browman, Gladys J.; Dennison, Jennifer B.; Vykoukal, Jody; Luna, Pamela N.; Siu, Wesley; Wu, Ranran; Murage, Eunice; Ajami, Nadim J.; Mcquade, Jennifer L.; Wargo, Jennifer A.; Long, James P.; Do, Kim-Anh; Lampe, Johanna W.; Basen-Engquist, Karen M.; Okhuysen, Pablo C.; Kopetz, Scott; Hanash, Samir M.; Petrosino, Joseph F.; Scheet, Paul; Daniel, Carrie R. Share Save
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment Schwabkey, Zaker I.; Wiesnoski, Diana H.; Chang, Chia-Chi; Tsai, Wen-Bin; Pham, Dung; Ahmed, Saira S.; Hayase, Tomo; Turrubiates, Miriam R. Ortega; El-Himri, Rawan K.; Sanchez, Christopher A.; Hayase, Eiko; Oquendo, Annette C. Frenk; Miyama, Takahiko; Halsey, Taylor M.; Heckel, Brooke E.; Brown, Alexandria N.; Jin, Yimei; Raybaud, Mathilde; Prasad, Rishika; Flores, Ivonne; McDaniel, Lauren; Chapa, Valerie; Lorenzi, Philip L.; Warmoes, Marc O.; Tan, Lin; Swennes, Alton G.; Fowler, Stephanie; Conner, Margaret; McHugh, Kevin; Graf, Tyler; Jensen, Vanessa B.; Peterson, Christine B.; Do, Kim-Anh; Zhang, Liangliang; Shi, Yushu; Wang, Yinghong; Galloway-Pena, Jessica R.; Okhuysen, Pablo C.; Daniel-MacDougall, Carrie R.; Shono, Yusuke; da Silva, Marina Burgos; Peled, Jonathan U.; van den Brink, Marcel R. M.; Ajami, Nadim; Wargo, Jennifer A.; Reddy, Pavan; Valdivia, Raphael H.; Davey, Lauren; Rondon, Gabriela; Srour, Samer A.; Mehta, Rohtesh S.; Alousi, Amin M.; Shpall, Elizabeth J.; Champlin, Richard E.; Shelburne, Samuel A.; Molldrem, Jeffrey J.; Jamal, Mohamed A.; Karmouch, Jennifer L.; Jeng, Robert R. Share Save
Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure Karpinets, Tatiana V.; Wu, Xiaogang; Solley, Travis; El Alam, Molly B.; Sims, Travis T.; Yoshida-Court, Kyoko; Lynn, Erica; Ahmed-Kaddar, Mustapha; Biegert, Greyson; Yue, Jingyan; Song, Xingzhi; Sun, Huandong; Petrosino, Joseph F.; Mezzari, Melissa P.; Okhuysen, Pablo; Eifel, Patricia J.; Jhingran, Anuja; Lin, Lilie L.; Schmeler, Kathleen M.; Ramondetta, Lois; Ajami, Nadim; Jenq, Robert R.; Futreal, Andrew; Zhang, Jianhua; Klopp, Ann H.; Colbert, Lauren E. Share Save
Fully resolved assembly of Cryptosporidium parvum Menon, Vipin K.; Okhuysen, Pablo C.; Chappell, Cynthia L.; Mahmoud, Medhat; Mahmoud, Medhat; Meng, Qingchang; Doddapaneni, Harsha; Vee, Vanesa; Han, Yi; Salvi, Sejal; Bhamidipati, Sravya; Kottapalli, Kavya; Weissenberger, George; Shen, Hua; Ross, Matthew C.; Hoffman, Kristi L.; Cregeen, Sara Javornik; Muzny, Donna M.; Metcalf, Ginger A.; Gibbs, Richard A.; Petrosino, Joseph F.; Sedlazeck, Fritz J. Share Save
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Safety and efficacy of fecal microbiota transplantation to treat and prevent recurrent Clostridioides difficile in cancer patients Ali, Hiba; Khurana, Shruti; Ma, Weijie; Peng, Yuanzun; Jiang, Zhi-Dong; DuPont, Herbert; Zhang, Hao Chi; Thomas, Anusha S.; Okhuysen, Pablo; Wang, Yinghong Share Save
Telomere dysfunction activates YAP1 to drive tissue inflammation Chakravarti, Deepavali; Hu, Baoli; Mao, Xizeng; Rashid, Asif; Li, Jiexi; Li, Jun; Liao, Wen-ting; Whitley, Elizabeth M.; Dey, Prasenjit; Hou, Pingping; LaBella, Kyle A.; Chang, Andrew; Wang, Guocan; Spring, Denise J.; Deng, Pingna; Zhao, Di; Liang, Xin; Lan, Zhengdao; Lin, Yiyun; Sarkar, Sharmistha; Terranova, Christopher; Deribe, Yonathan Lissanu; Blutt, Sarah E.; Okhuysen, Pablo; Zhang, Jianhua; Vilar, Eduardo; Nielsen, Ole Haagen; Dupont, Andrew; Younes, Mamoun; Patel, Kalyani R.; Shroyer, Noah F.; Rai, Kunal; Estes, Mary K.; Wang, Y. Alan; Bertuch, Alison A.; DePinho, Ronald A. Share Save
Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients Olvera, Adilene; Carter, Hannah; Rajan, Anubama; Carlin, Lily G.; Yu, Xiaomin; Zeng, Xi-Lei; Shelburne, Samuel; Bhatti, Micah; Blutt, Sarah E.; Shroyer, Noah F.; Jenq, Robert; Estes, Mary K.; Maresso, Anthony; Okhuysen, Pablo C. Share Save
Clostridioides difficile Infection in Cancer and Immunocompromised Patients: Relevance of a Two-step Diagnostic Algorithm and Infecting Ribotypes on Clinical Outcomes Guevara, Eduardo A. Yepez; Aitken, Samuel L.; Olvera, Adilene, V; Carlin, Lily; Fernandes, Kerri E.; Bhatti, Micah M.; Garey, Kevin W.; Adachi, Javier; Okhuysen, Pablo C. Share Save
Neutropenic Enterocolitis: Clinical Features and Outcomes Abu-Sbeih, Hamzah; Ali, Faisal S.; Chen, Ellie; Mallepally, Niharika; Luo, Wenyi; Lu, Yang; Foo, Wai Chin; Qiao, Wei; Okhuysen, Pablo C.; Adachi, Javier A.; Hachem, Ray Y.; Altan, Mehmet; Jenq, Robert R.; Wang, Yinghong Share Save
The BE GONE trial study protocol: a randomized crossover dietary intervention of dry beans targeting the gut microbiome of overweight and obese patients with a history of colorectal polyps or cancer Zhang, Xiaotao; Browman, Gladys; Siu, Wesley; Basen-Engquist, Karen M.; Hanash, Samir M.; Hoffman, Kristi L.; Okhuysen, Pablo C.; Scheet, Paul; Petrosino, Joseph F.; Kopetz, Scott; Daniel, Carrie R. Share Save
Impact of antibiotic therapy on the development and response to treatment of immune checkpoint inhibitor-mediated diarrhea and colitis (vol 7, 242, 2019) Abu-Sbeih, Hamzah; Herrera, Lauren Nicholas; Tang, Tenglong; Altan, Mehmet; Chaftari, Anne-Marie; Okhuysen, Pablo C.; Jenq, Robert R.; Wang, Yinghong Share Save
Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli Kuhlmann, F. Matthew; Martin, John; Hazen, Tracy H.; Vickers, Tim J.; Pashos, Madeline; Okhuysen, Pablo C.; Gomez-Duarte, Oscar G.; Cebelinski, Elizabeth; Boxrud, Dave; del Canto, Felipe; Vidal, Roberto; Qadri, Firdausi; Mitreva, Makedonka; Rasko, David A.; Fleckenstein, James M. Share Save
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Telomere dysfunction is a driver of inflammatory bowel disease Chakravarti, Deepavali; Multani, Asha; Dey, Prasenjit; Hu, Baoli; Zhao, Di; Chang, Kyle; Xizeng, Mao; Wang, Guocan; Terranova, Christoper; Liao, Wen-Ting; Spring, Denise; Hou, Pingping; Zhang, Jianhua; Okhuysen, Pablo; Vilar, Eduardo; Estes, Mary K.; Blutt, Sarah; Wang, Alan; DePinho, Ronald Share Save
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